Sujet(s)
Malformations dues aux médicaments et aux drogues/épidémiologie , Anticonvulsivants/effets indésirables , Épilepsie/traitement médicamenteux , Complications de la grossesse/traitement médicamenteux , Effets différés de l'exposition prénatale à des facteurs de risque/épidémiologie , Malformations dues aux médicaments et aux drogues/étiologie , Anticonvulsivants/administration et posologie , Enfant d'âge préscolaire , Épilepsie/physiopathologie , Femelle , Humains , Nourrisson , Grossesse , Complications de la grossesse/physiopathologie , Effets différés de l'exposition prénatale à des facteurs de risque/étiologieSujet(s)
Grippe humaine/microbiologie , Grippe humaine/prévention et contrôle , Muqueuse nasale/microbiologie , Infections de l'appareil respiratoire/microbiologie , Infections de l'appareil respiratoire/prévention et contrôle , Maladie aigüe , Aérosols , Enfant , Humains , Vaccins antigrippaux/administration et posologie , Grippe humaine/virologie , Solution isotonique/usage thérapeutique , Muqueuse nasale/virologie , Infections de l'appareil respiratoire/virologieSujet(s)
Lymphocytes B/immunologie , Déficits immunitaires/diagnostic , Lymphocytes T/immunologie , Adjuvants immunologiques/administration et posologie , Production d'anticorps , Lymphocytes B/anatomopathologie , Association thérapeutique , Humains , Déficits immunitaires/immunologie , Déficits immunitaires/thérapie , Immunothérapie , Nouveau-né , Numération des leucocytes/effets des médicaments et des substances chimiques , Peptides/administration et posologie , Lymphocytes T/anatomopathologie , Extrait thymus/administration et posologieRÉSUMÉ
The content of purine compounds in red blood cells was measured and compared in 21 neonates with a history of chronic intrauterine hypoxia, depending on the condition at birth and the early period of adaptation. The content of purine compounds in whole blood was measured at the moment of birth and on days 1, 3 and 5 of life. It has been disclosed that the pattern of purine metabolism abnormality in funic red blood cells makes it possible to predict the course of the early period of adaptation. Changes in the content of hypoxanthine and inosine monophosphate appeared to be most remarkable.
Sujet(s)
Érythrocytes/métabolisme , Hypoxie foetale/sang , Nouveau-né/sang , Purinones/sang , Maladie chronique , Femelle , Humains , Grossesse , Facteurs tempsRÉSUMÉ
The authors describe the results of studying lipid peroxidation, total antioxidant activity of plasma and the content of essential trace elements (iron, copper, zinc and selenium) in 35 healthy neonates and in 32 with intrauterine hypotrophy, grades I-III, at birth and the course of the early neonatal period. It has been found that in the neonates with a history of intrauterine hypotrophy, activation of lipid peroxidation resulted in the decrease of plasma antioxidant activity and in the changes of the concentration of essential trace elements.
Sujet(s)
Retard de croissance intra-utérin/métabolisme , Nouveau-né/métabolisme , Peroxydation lipidique , Oligoéléments/sang , Femelle , Humains , Malonaldéhyde/sang , Grossesse , Valeurs de référenceSujet(s)
Enseignement médical/tendances , Rôle médical , Psychodrame , Jeu de rôle , Rôle , Enseignement/méthodes , URSSRÉSUMÉ
Emission analysis with the use of induced plasma was employed to measure the content of 9 bioelements (potassium, sodium, calcium, magnesium, phosphorus, iron, copper, zinc and selenium) in the blood serum of 82 neonates with a history of chronic intrauterine hypoxia and in 19 normal children at birth and in the course of early adaptation. It has been shown that the content of bioelements in the blood of normal neonates was marked by a number of characteristic features reflecting to a considerable degree the processes of metabolic adaptation of the children to the intrauterine life. The neonates with a history of hypoxia demonstrated the unbalance of bioelements most pronounced by day 3 of life. The treatment instituted did not make the content of bioelements in the neonates' blood return to normal.