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Exp Biol Med (Maywood)
; 245(8): 748-757, 2020 04.
Article
de Anglais
| MEDLINE
| ID: mdl-32183553
RÉSUMÉ
IMPACT STATEMENT: The incidence of HFpEF continues to increase and â¼2/3 of the patient population are post-menopausal women. Unfortunately, most studies focus on the use of male animal models of remodeling. In this study, however, using female rats to set a model of pre-HFpEF, we provide insights to possible mechanisms that contribute to HFpEF development in humans that will lead us to a better understanding of the underlying pathophysiology of HFpEF.