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1.
Psychol Trauma ; 2024 Jun 27.
Article de Anglais | MEDLINE | ID: mdl-38934942

RÉSUMÉ

BACKGROUND: War and forced migration expose refugees to trauma and ongoing stress, often contributing to long-term psychological consequences. Typically, trauma exposure is assessed cumulatively; yet, trauma type may better predict psychological outcomes. This study examined the differential impact of cumulative trauma and trauma subtypes (victimization, death threat, accidental/injury) on postmigration trajectories of posttraumatic stress and anxiety in refugees. METHOD: Seventy-seven Syrian (88.3%) and Iraqi (9.1%) adult refugees self-reported prior trauma exposure and psychological symptoms at time of arrival in the United States and 2 years post. Linear mixed-effects modeling was performed to assess for associations between trauma variables and symptom trajectories. Models using cumulative trauma as a predictor were compared to models including the three trauma subtype variables as predictors, using pseudo-R² values to compare variance explained between the two methods of trauma measurement. RESULTS: Linear mixed-effects modeling indicated that prior exposure to victimization predicted progressively worsening posttraumatic stress disorder (PTSD) symptoms over time postmigration (b = .97, SE = .45, t = 2.14, p = .036). Cumulative trauma also predicted increasing PTSD symptoms (b = .124, SE = .06, t = 2.09, p = .041), but explained less variance than victimization (9% vs. 18.1%). Direct effects of cumulative trauma (p = .009) and victimization (p = .002) on anxiety severity emerged; however, anxiety symptoms did not change over time depending on prior trauma exposure. Accidents/injuries and death threats did not predict PTSD or anxiety. CONCLUSIONS: These findings can be leveraged toward focused identification of those at highest risk for progressive illness postmigration, thus providing empirical guidance for allocation of interventions and resources for refugees. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

2.
J Am Acad Child Adolesc Psychiatry ; 63(7): 681-683, 2024 Jul.
Article de Anglais | MEDLINE | ID: mdl-38570011

RÉSUMÉ

PLAIN LANGUAGE SUMMARY: In this article, the author reflects upon recent advancements in artificial intelligence (AI) technologies have led to profound discussions about AI's role in scientific research and education. AI technologies are now capable of summarizing and analyzing large volumes of data, creating presentations, and even drafting parts of scientific papers and grants with minimal human input. With their exponential ongoing advancements, they will become even more capable in doing these tasks. As boundaries between humans and AI blurs, serious questions arise about the future roles, responsibilities, and identity of academic researchers, intellectual property, publishing and grantsmanship, and equity in the world of AI potentiated research.


Sujet(s)
Intelligence artificielle , Humains , Écriture , Recherche biomédicale/normes
3.
Int J Soc Psychiatry ; 70(5): 915-925, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-38605592

RÉSUMÉ

IMPORTANCE: The ongoing Russian invasion of Ukraine marks a critical juncture in a series of events posing severe threat to the health of Ukrainian citizens. While recent reports reveal higher rates of PTSD in Ukrainian refugees following Russia's invasion - data for Ukrainians remaining at the warfront is inherently difficult to access. A primarily elderly demographic, Ukrainians in previously Russian-occupied areas near the front (UPROANF) are at particular risk. DESIGN: Data was sourced from screening questionnaires administered between March 2022 and July 2023 by mobile health clinics providing services to UPROANF. SETTING: Previously occupied villages in Eastern and Southern Ukraine. PARTICIPANTS: UPROANF attending clinics completed voluntary self-report surveys reporting demographics, prior health diagnoses, and PTSD symptom severity (n = 450; Meanage = 53.66; 72.0% female). EXPOSURE: Participants were exposed to Russian occupation of Ukrainian villages. MAIN OUTCOME AND MEASURES: The PTSD Checklist for the DSM-V (PCL-5) with recommended diagnostic threshold (i.e. 31) was utilized to assess PTSD prevalence and symptom severity. ANCOVA was used to examine hypothesized positive associations between (1) HTN and (2) loneliness and PTSD symptoms (cumulative and by symptom cluster). RESULTS: Between 47.8% and 51.33% screened positive for PTSD. Though cumulative PTSD symptoms did not differ based on HTN diagnostic status, those with HTN reported significantly higher PTSD re-experiencing symptoms (b = 1.25, SE = 0.60, p = .046). Loneliness was significantly associated with more severe cumulative PTSD symptoms (b = 1.29, SE = 0.31, p < .001), re-experiencing (b = 0.47, SE = 0.12, p < .001), avoidance (b = .18, SE = 0.08, p = .038), and hypervigilance (b = 0.29, SE = 0.13, p = .036). CONCLUSIONS AND RELEVANCE: PTSD prevalence was higher than other war-exposed populations. Findings highlight the urgent mental health burden among UPROANF, emphasizing the need for integrated care models addressing both trauma and physical health. Given the significance of loneliness as a risk factor, findings suggest the potential for group-based, mind-body interventions to holistically address the physical, mental, and social needs of this highly traumatized, underserved population.


Sujet(s)
Troubles de stress post-traumatique , Humains , Ukraine/épidémiologie , Troubles de stress post-traumatique/épidémiologie , Femelle , Mâle , Adulte d'âge moyen , Prévalence , Adulte , Sujet âgé , Russie/épidémiologie , Enquêtes et questionnaires , Réfugiés/psychologie , Réfugiés/statistiques et données numériques
4.
Compr Psychoneuroendocrinol ; 16: 100217, 2023 Nov.
Article de Anglais | MEDLINE | ID: mdl-38108032

RÉSUMÉ

Refugees and internally displaced people comprise one percent of the world population. Forced migration involves a multitude of ongoing stressful and traumatic experiences, often resulting in lasting psychological symptoms for people resettling as refugees. Despite these risks, the underrepresentation of refugee populations in research-particularly in biological sciences-has impeded the allocation of effective resources and the development of novel interventions for these groups. This paper identifies and addresses key methodological challenges to successfully and appropriately conducting research with refugee and internally displaced communities, many of which have served as barriers to improving research representation for these populations. Methodological challenges discussed include language and literacy barriers; political fears; differing cultural dynamics between participants and researchers; and others. We provide practical recommendations for overcoming each challenge, often sourced from our experience conducting multi-year studies and interventions in refugee mental health. Several key strategies include the recruitment of researchers and research assistants from similar cultural and linguistic backgrounds as participants; providing detailed, ongoing communication about informed consent; avoiding assumptions regarding participants' understanding of concepts that may vary based on culture or experience (e.g., "voluntary" research; confidentiality); and adopting flexible data collection procedures compatible with participants' needs and restrictions. Finally, we discuss the role of the researcher in regard to cultural competencies and partnering with the refugee community. Given the increasing global population of refugees, the strategies discussed in this paper are suggested in order to encourage future research in this underrepresented population and empower investigators to logistically carry out studies with refugees.

5.
Psychol Trauma ; 2023 Nov 30.
Article de Anglais | MEDLINE | ID: mdl-38032625

RÉSUMÉ

OBJECTIVE: Trauma exposure-a contributor to psychological risk for refugee youth-is typically assessed using cumulative indices; however, recent findings indicate that trauma type may better predict psychological outcomes. This study investigated the utility of two methods of classifying trauma exposure-cumulative trauma and exposure to specific types of trauma (i.e., trauma subtypes)-in predicting the severity of symptoms related to posttraumatic stress disorder (PTSD) and anxiety for refugee youth. METHOD: 96 Syrian and Iraqi youth resettled as refugees in the United States self-reported trauma exposure and psychological symptoms. Multiple regression was used to assess the variance in symptom severity explained by specific trauma subtypes (i.e., victimization, death threat, and accidental/injury) as compared to cumulative trauma scores. RESULTS: Multiple regression models predicting PTSD revealed cumulative trauma (b = 0.07; p = .004) and death threat trauma (b = 0.16; p = .001) as significant predictors of PTSD symptom severity; notably, death threat trauma was the only subtype associated with PTSD and explained more variance than cumulative trauma scores (10.3% and 8.4%, respectively). Cumulative trauma, but no specific trauma subtype, was associated with anxiety (b = .03; p = .043); however, this relation did not survive correction for multiple comparisons. CONCLUSION: Focused trauma assessment-particularly consideration of death threat trauma and cumulative trauma exposures-may be useful in evaluating the risk of PTSD symptoms in refugee youth, whereas symptoms related to anxiety may be driven by other factors. These findings can be leveraged toward focused identification of youth at highest risk for PTSD symptoms, to improve prevention and early intervention efforts. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

6.
Avicenna J Med ; 13(2): 82-88, 2023 Apr.
Article de Anglais | MEDLINE | ID: mdl-37435556

RÉSUMÉ

Background Posttraumatic stress disorder (PTSD) is associated with disturbed sleep. However, the impact of sleep disturbances and PTSD symptomology in refugee populations is not well known. This study examined how PTSD-related sleep symptoms and overall sleep quality were impacted by previous and current traumatic and stressful experiences. Methods Adult Syrian refugees living in Southeast Michigan were assessed via scheduled in-home interviews. Overall sleep quality was measured using the Pittsburgh Sleep Quality Index. PTSD-related sleep disturbances were measured using the Pittsburgh Sleep Quality Index Addendum. The presence of PTSD symptomatology was assessed via self-report using the Posttraumatic Stress Disorder Checklist. The Life Events Checklist for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition-5 screened for prior traumatic events experienced and the Postmigration Living Difficulties Questionnaire was assessed for postmigration stressors. Correlational analysis was conducted between overall sleep quality, PTSD symptom severity, and previous trauma experienced. A stepwise linear regression analysis was conducted to examine the role of overall sleep quality, PTSD-specific sleep disturbances, current living difficulties, and the number of preimmigration traumatic events directly experienced or witnessed due to the presence of overall PTSD symptomology. Results A total of 53 adults completed the study. PTSD-disturbed sleep was found to be positively associated with overall poor sleep quality ( r = 0.42, p < 0.01), PTSD symptomology ( r = 0.65, p < 0.01), and current living difficulties ( r = 0.37, p < 0.05). The PTSD-related sleep disturbances (B = 0.66, p < 0.01) and postmigration living difficulties (B = 0.44, p < 0.01) were found to be the strongest predictors of PTSD symptoms. Conclusion Disturbed sleep is strongly associated with current stressful experiences and PTSD symptomology among Syrian refugees.

7.
Int J Soc Psychiatry ; 69(7): 1833-1836, 2023 Nov.
Article de Anglais | MEDLINE | ID: mdl-37278010

RÉSUMÉ

BACKGROUND: War and natural disasters lead to forced migration - and increased risk of adverse psychological outcomes - in approximately 1% of the global population. Though recent years have brought a greater understanding of the consequences of war exposure on mental health outcomes for refugee children, little is known about the longitudinal and developmental impact of these experiences on youth. AIMS: The aim of this study was to assess the effect of direct exposure to war and/or combat on trajectories of symptoms related to anxiety and post-traumatic stress disorder (PTSD) in Syrian and Iraqi refugee youth following resettlement. Prevalence of possible anxiety disorders and PTSD was also assessed. METHOD: Participants included accompanied refugee youth resettled in the state of Michigan in the U.S. (n = 74). Youth filled out self-report measures of trauma exposure, anxiety symptoms, and PTSD symptoms upon arrival and 2 years later. Linear mixed-effects modeling was used to assess the effect of war exposure over time. RESULTS: Upon arrival, 38% screened positive for an anxiety disorder and 4.1% met diagnostic thresholds for PTSD. While war exposure did not predict changes to PTSD symptom trajectories (p = .481), anxiety symptoms increased over time among children reporting war exposure (B = 10.13, SE = 4.22, t = 2.40, p = .019). CONCLUSIONS: Our findings suggest that without appropriate interventions, anxiety- and trauma-related symptoms often do not decrease. Further, exposure to war trauma may lead to progressive worsening of symptoms. These findings suggest that assessing for type of trauma exposure, rather than focusing solely on migration status, may inform focused attention and interventions among trauma-exposed children resettling as refugees.


Sujet(s)
Réfugiés , Troubles de stress post-traumatique , Enfant , Humains , Adolescent , Réfugiés/psychologie , Syrie , Iraq/épidémiologie , Troubles de stress post-traumatique/épidémiologie , Troubles de stress post-traumatique/étiologie , Exposition à la guerre/effets indésirables
8.
Dev Psychobiol ; 65(4): e22385, 2023 05.
Article de Anglais | MEDLINE | ID: mdl-37073587

RÉSUMÉ

Fear-potentiated startle (FPS) can be used to measure fear and safety learning-behaviors affected by trauma that may map onto posttraumatic stress disorder (PTSD). Therefore, FPS could be a candidate biomarker of trauma-related psychopathology and a potential identifier of trauma-exposed youth in need of focused treatment. We enrolled n = 71 (35 females, Mage  = 12.7 years) Syrian youth exposed to civilian war trauma. Eyeblink electromyogram (EMG) data from a differential conditioning FPS paradigm were obtained 2.5 years after resettlement. Youth provided self-report of trauma exposure (Harvard Trauma Questionnaire) and PTSD symptoms (UCLA PTSD Reaction Index). While FPS during conditioning was not associated with symptoms, associations with psychopathology emerged in fear extinction. Probable PTSD was associated with FPS in the last block of extinction, such that FPS to threat cue was significantly greater in the PTSD+ group compared to the PTSD- group at the end of extinction (F = 6.25, p = .015). As with adults, we observed a deficit in extinction learning but not fear conditioning in youth with PTSD. These results support the use of trauma-informed cognitive behavioral therapy based on the learning principles of extinction in youth with PTSD.


Sujet(s)
Réfugiés , Troubles de stress post-traumatique , Adulte , Femelle , Humains , Adolescent , Enfant , Extinction (psychologie) , Conditionnement classique , Peur , Réflexe de sursaut
9.
Arts Psychother ; 832023 Apr.
Article de Anglais | MEDLINE | ID: mdl-37006325

RÉSUMÉ

This paper describes a program informed by art therapy and Photovoice approaches and techniques aimed at helping new immigrant and refugee teens to navigate personal and cultural identities by reflecting on their experiences as new residents in the US. Photovoice is a photography and social action method that encourages participants to photograph aspects of their daily lives, reflect on their meaning and significance and galvanize necessary changes. The program began in February 2020 at the Arab-American National Museum (AANM), but was adapted for an online format and re-framed towards a reflection on the COVID-19 pandemic. Broad questions teens explored included: What is good? What is challenging? What is sustaining during challenging times? What needs to change? and What about your culture and background are you proud of and wish to share with other US residents? Highlights of the sessions demonstrate how art therapy interventions paralleled photography-assigned themes of self, home, and community and encouraged group interaction and mutual support. A virtual museum exhibition culminated the program and reached community leaders. Self-reports from select participants highlight changes in posttraumatic stress, anxiety, and somatic symptoms over the course of programming.

10.
Int J Soc Psychiatry ; 69(5): 1268-1276, 2023 08.
Article de Anglais | MEDLINE | ID: mdl-36866463

RÉSUMÉ

BACKGROUND: Syrian and Iraqi refugees are a growing segment of the U.S. population, and although exposure to war and violence has been linked to psychological distress in individual refugees, few studies have examined the distress in married couples. METHODS: Using a cross-sectional design, a convenience sample of 101 Syrian and Iraqi refugee couples was recruited from a community agency. The purpose of this study was to (1) examine the relationships between perceived adversity and psychological distress (PTSD, anxiety, and depressive symptoms) among individual study participants; and (2) determine whether these relationships were correlated to their spouses' perceived adversity and psychological distress. RESULTS: The bivariate correlation analysis showed strong positive correlations between PTSD and depression/anxiety for wives (r = .79; p < .001) and for husbands (r = .74; p < .001). There were also low- to mid-range positive cross-associations between husbands' and wives' PTSD (r = .34; p = .001) and depression/anxiety (r = .43; p < .001). Finally, we found a significant positive association between husbands' and wives' perception of adversity (r = .44; p < .001). Interestingly, the husbands' perception of adversity was positively associated with their PTSD (r = .30; p = .02) and depression/ anxiety scores (r = .26; p = .04) as well as with their wives' depression/ anxiety scores (r = .23; p = .08). In contrast, the wives' perception of adversity was not associated with either their own or their spouses' psychological distress. CONCLUSION: Our findings suggest that war, trauma, and stress of migration impact the couple as a unit, possibly due to shared experiences, and the impact of one partner's stress on the other. Addressing these perceptions and personal interpretations of the adverse experiences via cognitive therapy approaches could help reduce not only stress in the individual but also that of their partner.


Sujet(s)
Détresse psychologique , Réfugiés , Humains , États-Unis , Études transversales , Mariage/psychologie , Conjoints/psychologie
12.
J Immigr Minor Health ; 25(2): 274-281, 2023 Apr.
Article de Anglais | MEDLINE | ID: mdl-36260186

RÉSUMÉ

Pre-migration trauma, a psychological risk factor for refugees, is often measured using cumulative indices. However, recent research suggests that trauma subtypes, rather than cumulative trauma, may better predict psychological outcomes. This study investigated the predictive utility of trauma subtypes in the assessment of refugee mental health. Multiple regression was used to determine whether cumulative trauma or trauma subtypes explained more variance in depression, anxiety, and post-traumatic stress disorder (PTSD) symptom scores in 70 Syrian and Iraqi refugees. Subtype models performed better than cumulative trauma models for PTSD (cumulative R2 = 0.138; subtype R2 = 0.32), anxiety (cumulative R2 = 0.061; subtype R2 = 0.246), and depression (cumulative R2 = 0.041; subtype R2 = 0.184). Victimization was the only subtype significantly associated with PTSD (p < 0.001; r2 = 0.210), anxiety (p < 0.001; r2 = 0.162), and depression (p = 0.002; r2 = 0.140). Cumulative trauma was predictive of PTSD symptoms only (p = 0.003; r2 = 0.125). Trauma subtypes were more informative than cumulative trauma, indicating their utility for improving predictive efforts in research and clinical contexts.


Sujet(s)
Réfugiés , Troubles de stress post-traumatique , Humains , Réfugiés/psychologie , Dépression , Troubles de stress post-traumatique/diagnostic , Troubles de stress post-traumatique/psychologie , Anxiété ,
13.
Eur J Psychotraumatol ; 13(2): 2104009, 2022.
Article de Anglais | MEDLINE | ID: mdl-35959204

RÉSUMÉ

Russian invasion of Ukraine has led to one of the largest refugee crises in recent history. Many internally displaced Ukrainians and refugees will need care for PTSD, anxiety, and depression. Here I will suggest practical steps to reduce long-term impact of trauma and stress on refugees' mental and physical health, and functioning. These include mental health first aid in acute phase of arrival, education of mental health and navigating healthcare system in the host countries. As well, training of manualized trauma-focused therapy and intervention methods in the host countries, focused education for physicians on psychopharmacological interventions for common mental health issues among refugees (PTSD, depression, anxiety), and utilization of videoconferencing for treatment, and consultation and supervision for providers. Highlights: Many internally displaced Ukrainians and refugees will need care for PTSD, anxiety, and depression to prevent long-term disability and health consequences.There are challenges in receiving the needed care including stigma, lack of awareness by patients and providers, lack of resources, and lack of skills in trauma-focused treatments.In this article, suggestions are made on how to overcome these obstacles, that include mental health first aid upon arrival, education for refugees and those serving them, training providers at different layers, and remote treatment and counselling/supervision services.


La invasión rusa a Ucrania ha provocado una de las mayores crisis de refugiados en la historia actual. Muchos ucranianos desplazados internamente y refugiados necesitarán de atención por TEPT, ansiedad y depresión. Aquí sugeriré pasos prácticos para reducir el impacto a largo plazo del trauma y estrés en la salud mental y física y funcionamiento de los refugiados. Estos incluyen primeros auxilios en la salud mental en la fase aguda de llegada, educación en salud mental y orientación en el sistema de servicios de salud en los países de acogida. Además, capacitación en terapia centrada en trauma manualizada y métodos de intervención en los países de acogida, educación focalizada para los médicos en intervenciones psicofarmacológicas para problemas de salud mental comunes entre los refugiados (TEPT, depresión, ansiedad) y utilización de videoconferencias para el tratamiento y consulta y supervisión para los proveedores.


Sujet(s)
Réfugiés , Troubles de stress post-traumatique , Anxiété/psychologie , Humains , Santé mentale , Psychothérapie , Réfugiés/psychologie , Troubles de stress post-traumatique/thérapie
14.
Eur J Psychotraumatol ; 13(1): 2083375, 2022.
Article de Anglais | MEDLINE | ID: mdl-35713586

RÉSUMÉ

Background: Posttraumatic stress symptoms (PTSS) include a constellation of physical and emotional profiles that youth exposed to trauma may experience. An estimated 20% of youth are exposed to trauma, and in refugee populations, up to 54% experience posttraumatic stress. Given the physical and mental health consequences associated with trauma exposure and subsequent psychopathology, identifying biomarkers of symptom severity is a top research priority.Objective: Previous research in adults found that skin conductance responses to trauma interview predicted current and future PTSS. We extended this method to refugee youth exposed to civilian war trauma and forced migration, to examine associations between PTSS and skin conductance in this uniquely vulnerable child and adolescent population.Methods: 86 refugee youth ages 7-17 years completed a trauma interview and assessment of self-reported PTSS. The mobile eSense app on a iPad was used to obtain continuous recordings of skin conductance level (SCL) during a trauma interview (trauma SCL). Skin conductance response (SCR) was calculated by subtracting the baseline SCL from the maximum amplitude of the trauma SCL.Results: SCL during trauma was significantly greater than baseline SCL, Trauma exposure was significantly associated with SCR to trauma interview, R2 = .084, p = .042. SCR to trauma interview was positively correlated with reexperiencing (R2 = .127, p = .028), and hyperarousal symptoms (R 2 = .123, p = .048).Conclusions: The present study provides evidence for feasibility of SCR to trauma interview as a candidate biomarker of PTSS in youth. This is the first study to look at SCR to trauma interview in youth resettled as refugees and is part of the limited but growing body of research to look at biomarkers in refugee cohorts more broadly. As the number of forcibly displaced persons surges, early detection and prevention of trauma-related psychology is becoming more important than ever. HIGHLIGHTS: Using the mobile eSense app, we demonstrate that skin conductance is measurable in a variety of research settings and that skin conductance response may be a biological indicator of trauma and related psychopathology - namely re-experiencing symptoms - in youth resettled as refugees.


Sujet(s)
Réfugiés , Troubles de stress post-traumatique , Adolescent , Adulte , Marqueurs biologiques , Enfant , Émotions , Humains , Psychopathologie , Réfugiés/psychologie , Troubles de stress post-traumatique/diagnostic
15.
J Am Acad Child Adolesc Psychiatry ; 61(11): 1322-1326, 2022 11.
Article de Anglais | MEDLINE | ID: mdl-35716921

RÉSUMÉ

At the Stress, Trauma and Anxiety Research Clinic (STARC) at Wayne State University in Detroit, we are currently amid data collection for a longitudinal prospective study of Syrian refugee children and their parents. Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, our goal is to understand the impact of exposure to war trauma and the stress of migration on symptoms of posttraumatic stress disorder, anxiety, and depression, as well as the neurobiological, epigenetic, and environmental correlates of risk and resilience. Like many research groups around the world, the COVID-19 pandemic brought our work to a screeching halt. Researchers who, like us, were engaged in human subjects research were left grappling with the question of how to continue their work while ensuring the safety of both research staff and participants, and while maintaining scientific integrity. In March 2020, our institution halted all in-person human subjects research that did not have direct benefits to participants, which continued until October, when research activity was resumed subject to implementation of modified procedures. Over the past 2 years, we have pivoted, adapted, and flexed, ultimately making changes that have allowed us to continue successful data collection throughout the pandemic. This article will discuss the specific challenges of working with ethnically minoritized and immigrant populations during the pandemic, the adaptations that we implemented to enable safe and effective data collection, as well as the new knowledge that we can apply to future research protocols.


Sujet(s)
COVID-19 , Réfugiés , Enfant , Humains , Pandémies , Populations vulnérables , Études prospectives
16.
Article de Anglais | MEDLINE | ID: mdl-35580738

RÉSUMÉ

Conflict and climate change continue to displace millions of people, who experience unique trauma and stressors as they resettle in host countries. Both children and adults who are forcibly displaced, or choose to migrate, experience posttraumatic stress disorder, anxiety, depression, and other mental health conditions at higher rates than the general population. This may be attributed to severe, cumulative stress and trauma (largely interpersonal traumas); discrimination and harassment in host countries; and structural barriers to accessing and addressing mental health concerns, including clinician availability, language barriers, cultural differences, geographic accessibility, health care access, and stigma. Despite high exposure to and clinical impact of such experiences, and despite representing 1% of the world population, forcibly displaced people are underrepresented in neuroscientific research. The availability of such literature and research findings is significant in understanding the unique genetic and cultural aspects of trauma- and stress-related mental health, advocacy, reducing stigma, informing prevention, and treatment. The present work aimed to explore how the field of neuroscience can address mental health equity for individuals who have been uprooted in relation to land, with a focus on refugee populations. We offer practical suggestions on how to improve research in this area and narrow the gap in knowledge.


Sujet(s)
Psychiatrie biologique , Neurosciences , Enfant , Humains
17.
Drug Alcohol Depend ; 234: 109430, 2022 05 01.
Article de Anglais | MEDLINE | ID: mdl-35367939

RÉSUMÉ

PURPOSE: Posttraumatic Stress Disorder (PTSD) is associated with increased alcohol use and alcohol use disorder (AUD), which are all moderately heritable. Studies suggest the genetic association between PTSD and alcohol use differs from that of PTSD and AUD, but further analysis is needed. BASIC PROCEDURES: We used genomic Structural Equation Modeling (genomicSEM) to analyze summary statistics from large-scale genome-wide association studies (GWAS) of European Ancestry participants to investigate the genetic relationships between PTSD (both diagnosis and re-experiencing symptom severity) and a range of alcohol use and AUD phenotypes. MAIN FINDINGS: When we differentiated genetic factors for alcohol use and AUD we observed improved model fit relative to models with all alcohol-related indicators loading onto a single factor. The genetic correlations (rG) of PTSD were quite discrepant for the alcohol use and AUD factors. This was true when modeled as a three-correlated-factor model (PTSD-AUD rG:.36, p < .001; PTSD-alcohol use rG: -0.17, p < .001) and as a Bifactor model, in which the common and unique portions of alcohol phenotypes were pulled out into an AUD-specific factor (rG with PTSD:.40, p < .001), AU-specific factor (rG with PTSD: -0.57, p < .001), and a common alcohol factor (rG with PTSD:.16, NS). PRINCIPAL CONCLUSIONS: These results indicate the genetic architecture of alcohol use and AUD are differentially associated with PTSD. When the portions of variance unique to alcohol use and AUD are extracted, their genetic associations with PTSD vary substantially, suggesting different genetic architectures of alcohol phenotypes in people with PTSD.


Sujet(s)
Alcoolisme , Troubles de stress post-traumatique , Consommation d'alcool/génétique , Alcoolisme/génétique , Étude d'association pangénomique , Humains , Analyse de structure latente , Troubles de stress post-traumatique/génétique
18.
AMA J Ethics ; 24(2): E111-119, 2022 02 01.
Article de Anglais, Espagnol | MEDLINE | ID: mdl-35324097

RÉSUMÉ

A clinician's standard primary role is to treat and monitor their patients' health and to be their ally. Clinicians with obligations to patients and to organizations, however, must also assess patients for nontherapeutic purposes (eg, readiness to resume work). These 2 obligations can conflict, and, when they do, clinicians must balance their duties to patients and to society. We propose criteria clinicians should consider when determining a patient's readiness to return to work and offer recommendations for interpreting factors that influence this decision.


La función principal de un médico es tratar y controlar la salud de sus pacientes, además de ser su aliado. Sin embargo, los médicos que tienen obligaciones con los pacientes y con las organizaciones también deben evaluar a los pacientes con fines no terapéuticos (p. ej., su disposición a reincorporarse al trabajo). Estas dos obligaciones pueden entrar en conflicto y, cuando lo hacen, los médicos deben equilibrar sus deberes con los pacientes y con la sociedad. Proponemos los criterios que los médicos deberían tener en cuenta al determinar si un paciente está preparado para volver al trabajo y ofrecemos recomendaciones para interpretar los factores que influyen en esta decisión.


Sujet(s)
Reprise du travail , Humains
19.
MCN Am J Matern Child Nurs ; 47(2): 92-99, 2022.
Article de Anglais | MEDLINE | ID: mdl-35202011

RÉSUMÉ

PURPOSE: The purpose of this study was to examine the relationships between acculturative stress, perceived stress, social support, and postpartum depression (PPD) symptoms among immigrant Arab American couples. METHODS: Using a cross-sectional design, 30 Arab American immigrant couples were enrolled. During home visits, couples completed the demographic information, the Multi-Dimensional Acculturative Stress Inventory, Perceived Stress, the Multidimensional Scale of Perceived Social Support among Arab Women, and the Edinburgh Postnatal Depression Scale. Data were analyzed using bivariate linear regression and Pearson correlation. RESULTS: In bivariate regressions, paternal and maternal acculturative stress was moderately associated with maternal PPD symptoms (r = .39, and .46, respectively; p < .05). Maternal perceived stress (r = .70, P < .01) was strongly associated with PPD and maternal perceived social support was moderately associated with PPD (r = -.42, p < .05). Maternal and paternal acculturative stress was strongly correlated (r = .61, p < .001). CONCLUSION: Couple's acculturative stress and mother's perceived stress were positively associated with mother's PPD symptoms. Our findings suggest the need to develop a culturally appropriate procedure to assess couple's stress that may affect immigrant women at high risk for PPD.


Sujet(s)
Dépression du postpartum , Émigrants et immigrants , Arabes , Études transversales , Dépression , Dépression du postpartum/diagnostic , Pères , Femelle , Humains , Mâle , Période du postpartum , Facteurs de risque , États-Unis
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