RÉSUMÉ
The investigation on Salvia przewalskii Maxim was carried out to find the relationship of the constituents and their pharmacological activities. The isolation and purification were performed by various chromatographies such as silica gel, Sephadex LH-20, RP-C18 column chromatography, etc. Further investigation on the fraction of the 95% ethanol extract of Salvia przewalskii Maxim yielded przewalskin Y-1 (1), anhydride of tanshinone-II A (2), sugiol (3), epicryptoacetalide (4), cryptoacetalide (5), arucadiol (6), 1-dehydromiltirone (7), miltirone (8), cryptotanshinone (9), tanshinone II A (10) and isotanshinone-I (11). Their structures were elucidated by the spectral analysis such as NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry). Compound 1 is a new compound. Compounds 4 and 5 are mirror isomers (1 : 3). Compounds 4, 5, 6, 8, 11 were isolated from Salvia przewalskii Maxim for the first time.
Sujet(s)
Diterpènes/isolement et purification , Médicaments issus de plantes chinoises/isolement et purification , Plantes médicinales/composition chimique , Salvia/composition chimique , Diterpènes/composition chimique , Médicaments issus de plantes chinoises/composition chimique , Structure moléculaire , Phénanthrènes/composition chimique , Phénanthrènes/isolement et purificationRÉSUMÉ
Two new phenolic compounds, 5-hydroxy-2-[2-(4-hydroxyphenyl) acetyl]-3-methoxylbenzoic acid (1) and (2S,3S)-3,7,8,3',4'-pentahydroxyflavane (2), were obtained from the aqueous extract of Acacia catechu, along with four known compounds identified as rhamnetin (3), 4-hydroxyphenyl ethanol (4), 3,3',5,5',7-pentahydroxyflavane (5), and fisetinidol (6). Their structures were determined on the basis of spectroscopic analysis. Free radical-scavenging activities of the new compounds were evaluated.
Sujet(s)
Acacia/composition chimique , Benzoates/isolement et purification , Médicaments issus de plantes chinoises/isolement et purification , Flavonoïdes/isolement et purification , Piégeurs de radicaux libres/isolement et purification , Phénols/isolement et purification , Benzoates/composition chimique , Benzoates/pharmacologie , Médicaments issus de plantes chinoises/composition chimique , Médicaments issus de plantes chinoises/pharmacologie , Flavonoïdes/composition chimique , Flavonoïdes/pharmacologie , Piégeurs de radicaux libres/composition chimique , Piégeurs de radicaux libres/pharmacologie , Structure moléculaire , Phénols/composition chimique , Phénols/pharmacologie , Quercétine/analogues et dérivés , Quercétine/composition chimique , EauRÉSUMÉ
OBJECTIVE: To study the chemical constituents from Faeces bombycis. METHOD: Isolation and purification were carried out on silic gel, Sephadex LH-20 and RP-18 column chromatography. The chemical structures of the constituents were elucidated on the basis of physicochemical properties and spectral data. RESULT: Fifteen compounds were identified as 3S, 5R-dihydroxy-6R, 7-megstigmadien-9-one (1), 3S, 5R-dihydroxy-6S, 7-megstigmadien-9-one (2), (6R, 9R)-3-oxo-alpha-ionol-beta-D-glucopyranoside (3), (6R, 9S)-3-oxo-alpha-ionol-beta-D-glucopyranoside (4), blumenol C glucoside (5), byzantionoside B (6), alangionoside L (7), lutein (8), pipecolic acid (9), betaine (10), alanine (11), glutamic acid (12), phenylalanine (13), leucine (14), isoleucine (15). CONCLUSION: All the compounds were separated from Faeces bombycis for the first time.
