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1.
Zhonghua Yu Fang Yi Xue Za Zhi ; 54(12): 1495-1498, 2020 Dec 06.
Article de Chinois | MEDLINE | ID: mdl-33333676

RÉSUMÉ

A novel coronavirus pneumonia outbreak in the world. The epidemic of the new coronavirus pneumonia has been preliminarily controlled successfully in China. At this time, how to construct the clinical laboratory in the hospital? This artical puts some forward thoughts, such as improve the construction of biological safety protection ability, detection ability, test platform construction, scientific research ability construction, personnel training and clinical communication ability, etc. These above advices could provide reference for the development direction of the clinical laboratory in post epidemic era.


Sujet(s)
COVID-19 , Épidémies , Chine/épidémiologie , Hôpitaux , Humains , Laboratoires , SARS-CoV-2
2.
Zhonghua Yi Xue Za Zhi ; 99(32): 2522-2526, 2019 Aug 27.
Article de Chinois | MEDLINE | ID: mdl-31484280

RÉSUMÉ

Objective: To retrospectively analyze the characteristics of the electromyography (EMG) study in generalized myasthenia gravis (gMG) patients. Methods: A total of 111 gMG patients were enrolled. Patients were divided into two groups: 36 severe patients discontinuing pyridostigmine bromide (PB) for 8 hours were included in 8 h group, and 75 g MG patients discontinuing PB for at least 18 hours were included in>18 h group. The clinical information and EMG study data were collected and analyzed. Results: There were statistically significant differences in the initial location of the myasthenia muscle (P=0.027), the affected muscle detected by the EMG (P=0.015) and quantitative myasthenia gravis (QMG) score (P<0.01) between the two groups. Comparisons in each group revealed that the highest positive rate of low-frequency repetitive nerve stimulation (RNS) of facial in 8 h group and>18 h group was 94.4% and 60.0%, respectively. Comparisons between the two groups showed that the positive rate of low-frequency RNS in 8 h group was significantly higher than that in>18 h group (94.4% vs 70.7%, χ(2)=8.115, P=0.004). In particular, the positive rate of RNS in facial nerves and the extent of the amplitude decrease under different electrical stimulations (1 Hz, 3 Hz, and 5 Hz) were dramatically higher in the 8 h group (P<0.01). Conclusions: For gMG patients, the facial and accessory nerve detection can improve the positive rate of RNS. Different muscles had various sensitivity to PB, and orbicularis oculi muscle seemed the least sensitive muscle to PB. For suspect MG patients in severe condition, only discontinuing PB medication for 8 h before low-frequency RNS testing can avoid the deterioration and also obtain similar positive rate.


Sujet(s)
Myasthénie , Stimulation électrique , Électromyographie , Muscles de la face , Humains , Études rétrospectives
3.
Geriatr Nurs ; 40(2): 154-159, 2019.
Article de Anglais | MEDLINE | ID: mdl-30173939

RÉSUMÉ

Depression leads to a poorer quality of life (QOL) which is a determinant of healthy ageing. Cost-effective solutions for enhancing QOL in the older population are much needed in China, with its rapidly ageing population. We conducted a randomized controlled trial involving 112 community-dwelling older participants with mild to moderate depression, to evaluate the effect of Tai Chi with music on QOL (57 in intervention group, 55 in control group). WHO Quality of Life-BREF was used to measure QOL at baseline and at every month for three months. Following the adjustments for sociodemographic data, the effect of intervention on QOL was assured (F = 25.145, P < 0.001, ηp2= 0.435, F = 18.696, P < 0.001, ηp2= 0.364, F = 17.473, P< 0.001, ηp2= 0.348, and F = 29.576, P < 0.001, ηp2= 0.475 for physical, psychological, social, and environment domains respectively). This intervention represents an economically viable solution to better QOL and healthy ageing in a highly populous developing nation.


Sujet(s)
Dépression/psychologie , Musique , Qualité de vie/psychologie , Tai Chi , Sujet âgé , Chine , Femelle , Humains , Vie autonome , Mâle
4.
Issues Ment Health Nurs ; 39(5): 398-402, 2018 May.
Article de Anglais | MEDLINE | ID: mdl-29436896

RÉSUMÉ

BACKGROUND: The effectiveness of pharmacological treatment may be limited in older persons. Several studies using Tai Chi or music therapy separately confirmed positive effects in the reduction of depressive symptoms. We conducted a cluster randomized controlled trial to evaluate the possible synergistic effect of combined music and Tai Chi on depressive symptoms. METHODS: One hundred and seven older adults with mild to moderate depressive symptoms were recruited from Ya'an city. Fifty-five participants were cluster randomized to combined music and Tai Chi group for three months, while the other fifty-two individuals were randomized to the control group that entailed routine health education delivered monthly by community nurses. The primary outcome of depressive symptoms was measured with the Geriatric Depression Scale (GDS) at baseline and monthly for three months. RESULTS: At three-month follow-up, a statistically significant improvement in depressive symptoms was found in the intervention group compared with control group (F(3,315) = 69.661, P < 0.001). Following adjustments for socio-demographic data, the true effect of intervention on depressive symptoms was significant (F = 41.725, P < 0.01, ηp2 = 0.574). CONCLUSIONS: Combined music and Tai Chi reduced depressive symptoms among community-dwelling older persons. This represents an economically viable solution to the management of depression in highly populous developing nations.


Sujet(s)
Dépression/thérapie , Musicothérapie , Tai Chi , Sujet âgé , Analyse de regroupements , Femelle , Humains , Vie autonome , Mâle , Adulte d'âge moyen
5.
Neuroscience ; 231: 225-32, 2013 Feb 12.
Article de Anglais | MEDLINE | ID: mdl-23232257

RÉSUMÉ

Neurological deficit following cerebral infarction correlates with not only primary injury, but also secondary neuronal apoptosis in remote loci connected to the infarction. Netrin-1 is crucial for axonal guidance by interacting with its receptors, deleted in colorectal cancer (DCC) and uncoordinated gene 5H (UNC5H). DCC and UNC5H are also dependence receptors inducing cell apoptosis when unbound by netrin-1. The present study is to investigate the role of netrin-1 and its receptors in ipsilateral ventroposterior thalamic nucleus (VPN) injury secondary to stroke in hypertensive rats. Renovascular hypertensive Sprague-Dawley rats underwent middle cerebral artery occlusion (MCAO). Continuous intracerebroventricular infusion of netrin-1 (600 ng/d for 7 days) or vehicle (IgG/Fc) was given 24h after MCAO. Neurological function was evaluated by postural reflex 8 and 14 days after MCAO. Then, immunoreactivity was determined in the ipsilateral VPN for NeuN, glial fibrillary acidic protein, netrin-1 and its receptors (DCC and UNC5H2), apoptosis was detected with Terminal deoxynucleotidyl transferase-mediated digoxigenin-dUTP-biotin nick-end labeling (TUNEL) assay, and the expressions of caspase-3, netrin-1, DCC, and UNC5H2 were quantified by western blot analysis. MCAO resulted in the impaired postural reflex after 8 and 14 days, with decreased NeuN marked neurons and increased TUNEL-positive cells, as well as an up-regulation in the levels of cleaved caspase-3 and UNC5H2 protein in the ipsilateral VPN, without significant change in DCC or netrin-1 expression. By exogenous netrin-1 infusion, the number of neurons was increased in the ipsilateral VPN, and both TUNEL-positive cell number and caspase-3 protein level were reduced, while UNC5H2 expression remained unaffected, simultaneously, the impairment of postural reflex was improved. Taken together, the present study indicates that exogenous netrin-1 could rescue neuron loss by attenuating secondary apoptosis in the ipsilateral VPN after focal cerebral infarction, possibly via its receptor UNC5H2, suggesting that relative insufficiency of endogenous netrin-1 be an underlying mechanism of secondary injury in the VPN post stroke.


Sujet(s)
Apoptose/effets des médicaments et des substances chimiques , Infarctus encéphalique/métabolisme , Hypertension rénovasculaire/métabolisme , Facteurs de croissance nerveuse/pharmacologie , Neurones/effets des médicaments et des substances chimiques , Noyaux du thalamus/effets des médicaments et des substances chimiques , Protéines suppresseurs de tumeurs/pharmacologie , Animaux , Antigènes nucléaires/métabolisme , Apoptose/physiologie , Infarctus encéphalique/complications , Récepteur DCC , Protéine gliofibrillaire acide/métabolisme , Hypertension rénovasculaire/complications , Mâle , Facteurs de croissance nerveuse/métabolisme , Protéines de tissu nerveux/métabolisme , Nétrine-1 , Neurones/métabolisme , Rats , Rat Sprague-Dawley , Récepteurs de surface cellulaire/métabolisme , Noyaux du thalamus/métabolisme , Protéines suppresseurs de tumeurs/métabolisme , Régulation positive/effets des médicaments et des substances chimiques , Régulation positive/physiologie
6.
J Hazard Mater ; 172(2-3): 1424-9, 2009 Dec 30.
Article de Anglais | MEDLINE | ID: mdl-19716230

RÉSUMÉ

A novel photodegradable polyethylene-goethite (PE-goethite) composite film was prepared by embedding the goethite into the commercial polyethylene. The degradation of PE-goethite composite films was investigated under ultraviolet light irradiation. The photodegradation activity of the PE plastic was determined by monitoring its weight loss, scanning electron microscopic (SEM) analysis and FT-IR spectroscopy. The weight of PE-goethite (1 wt%) sample steadily decreased and led to the total 16% reduction in 300 h under UV-light intensity for 1 mW/cm(2). Through SEM observation there were some cavities around the goethite powder in the composite films, but there were few changes except some surface chalking phenomenon in pure PE film. The degradation rate could be controlled by changing the concentration of goethite particles in PE plastic. The degradation of composite plastic initiated on PE-goethite interface and then extended into polymer matrix induced by the diffusion of the reactive oxygen species generated on goethite particle surface. The photocatalytic degradation mechanism of the composite films was briefly discussed.


Sujet(s)
Composés du fer/composition chimique , Processus photochimiques , Polyéthylènes/composition chimique , Rayons ultraviolets , Assainissement et restauration de l'environnement/méthodes , Composés du fer/effets des radiations , Cinétique , Minéraux , Polyéthylènes/effets des radiations , Espèces réactives de l'oxygène/composition chimique
7.
Chromosoma ; 114(1): 28-38, 2005 May.
Article de Anglais | MEDLINE | ID: mdl-15827746

RÉSUMÉ

A minilibrary was constructed from DOP-PCR products using microdissected Y-chromosomes of Indian muntjac as DNA templates. Two microclones designated as IM-Y4-52 and IM-Y5-7 were obtained from negative screening of all three cervid satellite DNAs (satellites I, II, and IV). These two microclones were 295 and 382 bp in size, respectively, and shared approximately 70% sequence homology. Southern blot analysis showed that the IM-Y4-52 clone was repetitive in nature with an approximately 0.32-kb register in HaeIII digest. Sequence comparison revealed no similarities to DNA sequences deposited in the GenBank database, suggesting that the microclone sequences were from a novel satellite DNA family designated as cervid satellite V. A subclone of an Indian muntjac BAC clone which screened positive for IM-Y4-52 had a 3,325-bp insert containing six intact monomers, four deleted monomers, and two partial monomers. The consensus sequence of the monomer was 328 bp in length and shared more than 80% sequence homology with every intact monomer. A zoo blot study using IM-Y4-52 as a probe showed that the strong hybridization with EcoRI digested male genomic DNA of Indian muntjac, Formosan muntjac, Chinese muntjac, sambar deer, and Chinese water deer. Female genomic DNA of Indian muntjac, Chinese water deer, and Formosan muntjac also showed positive hybridization patterns. Satellite V was found to specifically localize to the Y heterochromatin region of the muntjacs, sambar deer, and Chinese water deer and to chromosome 3 of Indian muntjac and the X-chromosome of Chinese water deer.


Sujet(s)
ADN satellite , Muntiacus/génétique , Chromosome Y/génétique , Animaux , Séquence nucléotidique , Évolution biologique , Chromosomes/ultrastructure , Femelle , Hybridation fluorescente in situ , Caryotypage , Mâle , Microdissection , Modèles génétiques , Séquences répétées d'acides nucléiques , Similitude de séquences d'acides nucléiques
8.
Cytogenet Genome Res ; 105(1): 100-6, 2004.
Article de Anglais | MEDLINE | ID: mdl-15218264

RÉSUMÉ

Due to their high sequence diversity even among closely related species, satellite DNA sequences can be a useful molecular marker for phylogenetic and taxonomic analyses. To characterize the satellite DNA in the genome of a native muntjac species of Taiwan, the Formosan muntjac, satellite DNA clones representing three different cervid satellite DNA families from this species were isolated and analyzed. Genomic organization study of these satellite DNAs was also undertaken. Three Formosan muntjac satellite DNA clones were obtained and designated as FM-satI (1,391 bp), FM-satII (1,143 bp) and FM-satIV (1,103 bp), and found to share approximately 82, 81 and 98% sequence homology with the Chinese muntjac satellite I clone (C5), Indian muntjac satellite II clone (Mmv-0.7) and Chinese muntjac satellite IV clone (MR-1.0), respectively. These three satellite DNA families are organized in a pter<--FM-satII-FM-satIV-FM-satI-->qter orientation in the centromeric region with satII closely associated with the telomeric sequences. Satellite DNA sequence comparison, in combination with chromosome data concludes that the Formosan muntjac is likely a subspecies of M. reevesi, closely related to the Chinese muntjac. With the kinetochore satellite II DNA co-localizing with the telomeric sequences, the Formosan muntjac chromosomes could be truly telocentric.


Sujet(s)
ADN satellite , Muntiacus/génétique , Animaux , Séquence nucléotidique , Technique de Southern , Lignée cellulaire , Centromère , Zébrage chromosomique , ADN satellite/génétique , ADN satellite/isolement et purification , Hybridation fluorescente in situ , Caryotypage , Données de séquences moléculaires , Cartographie physique de chromosome , Similitude de séquences d'acides nucléiques , Spécificité d'espèce
10.
Am J Physiol ; 277(3): H1081-8, 1999 09.
Article de Anglais | MEDLINE | ID: mdl-10484431

RÉSUMÉ

We have previously found that nicotine blocked multiple K+ currents, including the rapid component of delayed rectifier K+ currents (IKr), by interacting directly with the channels. To shed some light on the mechanisms of interaction between nicotine and channels, we performed detailed analysis on the human ether-à-go-go-related gene (HERG) channels, which are believed to be equivalent to the native I(Kr) when expressed in Xenopus oocytes. Nicotine suppressed the HERG channels in a concentration-dependent manner with greater potency with voltage protocols, which favor channel inactivation. Nicotine caused dramatic shifts of the voltage-dependent inactivation curve to more negative potentials and accelerated the inactivation process. Conversely, maneuvers that weakened the channel inactivation gating considerably relieved the blockade. Elevating the extracellular K+ concentration from 5 to 20 mM increased the nicotine concentration (by approximately 100-fold) needed to achieve the same degree of inhibition. Moreover, nicotine lost its ability to block the HERG channels when a single mutation was introduced to a residue located after transmembrane domain 6 (S631A) to remove the rapid channel inactivation. Our data suggest that the inactivation gating determines nicotine blockade of the HERG channels.


Sujet(s)
Transporteurs de cations , Protéines de liaison à l'ADN , Ouverture et fermeture des portes des canaux ioniques/effets des médicaments et des substances chimiques , Ouverture et fermeture des portes des canaux ioniques/physiologie , Nicotine/pharmacologie , Agonistes nicotiniques/pharmacologie , Canaux potassiques voltage-dépendants , Canaux potassiques/physiologie , Transactivateurs , Animaux , Relation dose-effet des médicaments , Canal potassique ERG1 , Canaux potassiques éther-à-go-go , Humains , Techniques de patch-clamp , Régulateur transcriptionnel ERG , Xenopus laevis
11.
Vet Hum Toxicol ; 41(4): 242-5, 1999 Aug.
Article de Anglais | MEDLINE | ID: mdl-10434380

RÉSUMÉ

The causes of Datura intoxication include medication overdose, misuse of edible vegetables, deliberate abuse as a hallucinogen, homicidal or robbery and accidental intoxication from contaminated food. We report an incident of 14 people with Datura intoxication caused by ingesting wild Datura suaveolans for food. The incubation period was 15 to 30 min. The symptoms/signs were dizziness, dry mouth, flushed skin, palpitation, nausea, drowsiness, tachycardia, blurred vision, mydriasis, hyperthermia, disorientation, vomiting, agitation, delirium, urine retention, hypertension and coma. Three patients were hospitalized for 2-3 days. Thirteen persons received supportive fluid therapy. One patient did not receive medical therapy, he induced vomiting and drank a lot of water. Four patients presented with delirium/coma and 3 received physostigmine therapy with good response. One patient was intubated because of coma and respiratory depression. Three persons needed Foley catheterization for urine retention or coma status. One patient had a complication of urinary tract infection and antibiotic management. All patients recovered with no sequelae.


Sujet(s)
Datura stramonium/intoxication , Feuilles de plante/intoxication , Plantes médicinales , Végétaux toxiques , Légumes , Adulte , Enfant , Anticholinestérasiques/usage thérapeutique , Femelle , Humains , Mâle , Adulte d'âge moyen , Physostigmine/usage thérapeutique
12.
Acupunct Electrother Res ; 17(4): 249-58, 1992.
Article de Anglais | MEDLINE | ID: mdl-1362035

RÉSUMÉ

In Huang Di Nei Jing Su Wen, among the materials which heretofore have no English translation, there are three Chapters on pain. One of them was devoted entirely to the low back pain. This is certainly an indication of its importance even more than 2,300 years ago. Since it still plagues us nowadays, we have translated that Chapter of this medical classic to see what we can learn from the ancients. We attempted to second guess the ancients in the diagnosis of the various sets of symptoms, in the light of western medicine. We discussed the difficulties in interpreting the archaic text. We pointed out that there were associations of the Mais (i.e., the Meridians) with various sets of symptoms but the loci of puncture were rather vaguely described and had no names. We inserted our selections of currently used acupoints to match the described loci. We would like to solicit our readers' comments.


Sujet(s)
Thérapie par acupuncture/histoire , Lombalgie/histoire , Médecine traditionnelle chinoise/histoire , Histoire ancienne , Humains , Lombalgie/thérapie
13.
Acupunct Electrother Res ; 17(3): 195-208, 1992.
Article de Anglais | MEDLINE | ID: mdl-1357925

RÉSUMÉ

We treated 61 cases of psoriasis with acupuncture, including 25 patients with complications of joint involvement and two cases with scleroderma additionally. All of the patients had failed to respond to their prior conventional western medical management. 25 patients were males and 36 were females. Their ages ranged from 22 to 84 years, with an average of about 52 years. There was no significant difference of the average ages between the sexes. Most of them (about 61%) had quite extensive involvement of the body. The average of duration of their illness was over 16 years, ranging from two to 65 years. They received an average of about nine sessions of acupuncture treatment, ranging from one to 15. Almost one third (19) of them had eleven to thirteen sessions. With the acupuncture treatment, about one-half (30) of the 61 patients had complete or almost complete clearance of the skin lesions. About a quarter (14 patients) of them had a clearance of about two thirds of the skin lesions. Eight of them had a clearance of one third of the skin lesions. Nine patients had minimal or no improvement. Our experience indicates that acupuncture is induced an effective therapeutic modality for psoriasis, particularly when the western medical management is unsuccessful. We speculated about the possible involvement of the cutaneous reticuloendothelial system in the clearance of the skin lesions.


Sujet(s)
Thérapie par acupuncture , Psoriasis/thérapie , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Loi du khi-deux , Femelle , Humains , Mâle , Adulte d'âge moyen , Études rétrospectives , Indice de gravité de la maladie
14.
Acupunct Electrother Res ; 17(1): 7-14, 1992.
Article de Anglais | MEDLINE | ID: mdl-1351340

RÉSUMÉ

Five Xing is an important integral in the traditional theoretic basis of acupuncture and traditional Chinese medicine. The word Xing has been translated as Element. However, it actually denotes movement and activity. The word element implies a stationary state. Some of the evidence in ancient Chinese literature was reviewed to support the hypothesis that Five Xing were originally meant to be the Five Xing Xin (Moving Stars, i.e., Planets). By the 4th century B.C., associations of the Stars with human events gradually evolved. However, between the 4th and the 6th century A.D., when the Taoist scholar-physicians expanded the Five Xing into abstractive concepts, they used the five basic materials as their representatives. Since they were basically alchemists and not astronomers, they apparently minimized the relationship between the Five Moving Stars and the human illnesses. It is, therefore, proposed that the usage of the word Element be discontinued and the word Xing be employed as is.


Sujet(s)
Thérapie par acupuncture/histoire , Astronomie/histoire , Terminologie comme sujet , Chine , Histoire ancienne , Humains
15.
Acupunct Electrother Res ; 16(3-4): 135-42, 1991.
Article de Anglais | MEDLINE | ID: mdl-1685622

RÉSUMÉ

Herpes simplex is a common skin disorder. There is no effective cure. The recent introduction of drugs, such as acyclovir, is indeed a great advance in its therapeutics. However, these drugs may only modestly reduce the length of an attack, but do not lengthen the remission nor prevent recurrences. Our very limited experience in two cases of herpes oral-labialis and three cases of herpes genitalis with acupuncture treatment seemed to indicate the possibility of a marked reduction of an episode, a lengthening of the remission, and a prevention of recurrences. We hope our report would encourage our colleagues to try acupuncture in the clinical management of herpes cases and to study its immunologic effects.


Sujet(s)
Thérapie par acupuncture/normes , Herpès génital/thérapie , Herpès labial/thérapie , Points d'acupuncture , Adulte , Femelle , Herpès génital/diagnostic , Herpès labial/diagnostic , Humains , Adulte d'âge moyen , Récidive
16.
Acupunct Electrother Res ; 13(1): 31-9, 1988.
Article de Anglais | MEDLINE | ID: mdl-2898197

RÉSUMÉ

Poison ivy contact dermatitis is fairly common in the suburbia of this country among amateur gardeners and children. It commonly inflicts its poison on the exposed parts of the limbs. The vesicular or bullous skin lesions are quite disturbingly itchy. Scratching the itchy lesions often spreads the condition by transplanting the remanent resinous toxin to other parts of the body. Though they are usually self-limiting, the intense itch is the main motivation for a patient to seek medical care. The conventional treatment is basically ineffective. During the summer of 1987 we treated four such cases of dermatitis with acupuncture upon their request to mollify their unbearable itch. They originally consulted with us for other problems. There were three males and one female. Their ages were between 29 and 63. Three cases were relatively mild and the fourth one was fairly severe. In the milder cases, their itch subsided in a few hours and skin lesions were healed in about two days after one treatment. In the severe case the itch subsided in about two days and most of the skin lesions dried up in four days after the first treatment and were healed almost completely after three sessions of acupuncture treatment. The plausible anti-inflammatory mechanism of acupuncture with the involvement of ACTH and/or cortisol was discussed.


Sujet(s)
Thérapie par acupuncture , Dermatite de contact au Rhus toxicodendron/thérapie , Adulte , Femelle , Humains , Mâle , Adulte d'âge moyen
17.
Acupunct Electrother Res ; 10(1-2): 41-66, 1985.
Article de Anglais | MEDLINE | ID: mdl-2861721

RÉSUMÉ

The re-introduction of acupuncture into the United States rekindled the interest in the management of chronic pain. Thermography has been shown to be a simple, non-invasive, reliable, and objective method to study pain. Our investigation included 81 patients with a variety of chronic pain conditions, one pain-free patients with left hemiparesis, and two normal subjects as controls. When pain was alleviated by acupuncture, thermography consistently demonstrated an increase of the infra-red radiation (IRR) of the affected parts of the body. Even though a patient might not report any reduction of pain, an elevation of the IRR of the affected site by acupuncture might imply the patient's denial of such an occurrence subconsciously or consciously. Acupuncture applied to pain-free patients tended to cause either no remarkable change of the infra-red pattern, or sometimes a slight decrease of the IRR if they experienced discomfort from needling. If normal thermographic patterns were observed in a patient with subjective pain, it practically excludes an actual existence of the complaint. The cooling effect of needling discomfort could be due to vasovagal over-activities. In conclusion, our investigation seemed to confirm that thermography indeed offered a simple, non-invasive, objective technique to study chronic pain and to provide an accurate measure of the effectiveness of acupuncture.


Sujet(s)
Thérapie par acupuncture , Température cutanée , Thermographie/instrumentation , Adulte , Facteurs âges , Sujet âgé , Maladie chronique , Femelle , Humains , Rayons infrarouges , Mâle , Adulte d'âge moyen , Gestion de la douleur , Facteurs sexuels
19.
Yale J Biol Med ; 51(1): 55-65, 1978.
Article de Anglais | MEDLINE | ID: mdl-209630

RÉSUMÉ

The controversy about acupuncture is familiar to us since its recent reintroduction into this country. Much of its philosophical concepts were taken at their face values as the bases for condemnation. Since I last reviewed these antiquated concepts in the light of modern medicine, much has developed. It seems that if the effects of acupuncture were transmitted along the peripheral nerves to the central nervous system, it would be more effective if applied segmentally to the site of noxious stimulation. Disruption of extralamniscal pathways would abolish its analgesic effect. The distant and nonsegmentally located acupuncture points exert their influences through the integrative efforts of the reticular formation and the thalamus. The demonstration of transmissibility of acupuncture analgesia through blood and cerebrospinal fluid in animals implicates the involvement of humoral factors. Since such an effect can be suppressed by naloxone or by hypophysectomy, endorphins are thought to be involved. Such laboratory evidences indeed begin to shed some light on a possible neurohumoral mechanism of acupuncture. The differences between acupuncture and hypnosis are discussed. Acupuncture points were compared with referred pain, trigger points and motor points of the skeletal muscles. Its possible uses for other than pain, such as drug addiction, alcoholism, etc. are also reviewed.


Sujet(s)
Thérapie par acupuncture , Douleur/physiopathologie , Analgésie , Animaux , Chimie du cerveau , Endorphines/pharmacologie , Haplorhini , Humains , Anesthésie hypnotique , Naloxone/pharmacologie , Voies nerveuses/physiologie , Lapins , Température cutanée , Transmission synaptique
20.
Conn Med ; 38(1): 39-42, 1974 Jan.
Article de Anglais | MEDLINE | ID: mdl-4813668
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