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J Biomed Mater Res A ; 101(4): 1036-46, 2013 Apr.
Article de Anglais | MEDLINE | ID: mdl-22965488

RÉSUMÉ

In this study, gelatin was blended to proprietary noncytotoxic polyurethanes (PU) derived from vegetable oils with different weight ratios, as material for the preparation of novel biomedical products. The PU/gelatin blends were characterized for their morphology through scanning electron microscopy. Mechanical and thermal properties, chemical interactions between components, degradation behavior, surface properties, cell adhesion, and bioactivity were investigated as a function of the protein content. Higher blend miscibility was observed for the amorphous PUs, derived from oleic acid. Properties of PU/gelatin films were strongly influenced by the concentration of gelatin in the films. Gelatin enhanced the hydrophilicity, bioactivity, and cell adhesion of PUs.


Sujet(s)
Gélatine/composition chimique , Test de matériaux , Membrane artificielle , Acide oléique/composition chimique , Huiles végétales/composition chimique , Polyuréthanes , Animaux , Bovins , Adhérence cellulaire , Souris , Cellules NIH 3T3 , Polyuréthanes/synthèse chimique , Polyuréthanes/composition chimique
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