Your browser doesn't support javascript.
loading
Montrer: 20 | 50 | 100
Résultats 1 - 1 de 1
Filtrer
Plus de filtres










Base de données
Gamme d'année
1.
Methods Mol Biol ; 2813: 1-17, 2024.
Article de Anglais | MEDLINE | ID: mdl-38888767

RÉSUMÉ

Intracellular pathogens comprise a diverse group of pathogens that all share a required location in a host cell to infect, survive, and replicate. Intracellular location allows pathogens to hide from host immune responses, avoid competition with other pathogens, mediate host cellular functions, replicate safely, and cause infection that is difficult to target with therapeutics. All intracellular pathogens have varying routes of infiltration into host cells and different host cell preferences. For example, bacteria Mycobacterium tuberculosis chooses to invade antigen-presenting cells, which allows them to moderate host antigen presentation to memory cells, whereas rabies virus prefers to invade neurons because they have pre-existing innate immunity protection systems. Regardless of the pathway that each intracellular pathogen follows, all share the capacity to cause disease if they succeed in entering host cells. Here, we give an overview of selected intracellular pathogens and infections they cause, immune responses they induce, and intervention strategies used to treat and control them.


Sujet(s)
Interactions hôte-pathogène , Humains , Animaux , Interactions hôte-pathogène/immunologie , Mycobacterium tuberculosis/immunologie , Mycobacterium tuberculosis/pathogénicité , Immunité innée , Virus de la rage/immunologie , Virus de la rage/pathogénicité
SÉLECTION CITATIONS
DÉTAIL DE RECHERCHE