RÉSUMÉ
BACKGROUND: Gastric carcinoma (GC) with second primary malignancy (SPM) is the most frequent combination within the multiple primary malignancies (MPM) group. The presentation of a GC associated with a synchronized SPM in the kidney is extremely rare and unusual. This study presents a rare case of synchronous tumors, describes the main associated risk factors, and emphasizes the need to rule out SPM. MAIN BODY: We present the case of a 63-year-old Hispanic woman with a history of smoking, weight loss, and gastrointestinal (GI) bleeding. GC was diagnosed by endoscopy, and during her workup for metastatic disease, a synchronous SPM was noted in the left kidney. The patient underwent resection of both tumors with a satisfactory postoperative course. A systematic review of the literature was performed using the Medline/PubMed, Science Direct, Scopus, and Google Scholar databases. A search of the literature yielded 13 relevant articles, in which the following main risk factors were reported: the treatment utilized, the grade and clinical stage, histopathological report, and in some cases survival. It is concluded that advanced age (> 60 years) and smoking are the main associated risk factors. CONCLUSION: Gastric carcinoma is the second most frequent neoplasm of the GI tract and the main neoplasm that presents a SPM. MPM screening is recommended in patients with gastric cancer. The clinical discovery of MPM of renal origin is rare and hence the importance of the current report.
Sujet(s)
Néphrocarcinome , Tumeurs du rein , Tumeurs primitives multiples , Seconde tumeur primitive , Tumeurs de l'estomac , Néphrocarcinome/imagerie diagnostique , Néphrocarcinome/chirurgie , Femelle , Humains , Tumeurs du rein/imagerie diagnostique , Tumeurs du rein/chirurgie , Adulte d'âge moyen , Tumeurs primitives multiples/chirurgie , Tumeurs de l'estomac/diagnostic , Tumeurs de l'estomac/chirurgieRÉSUMÉ
The vertical activity distribution and inventories of (239+240)Pu profile and Hg were determined in Sagua la Grande estuary, Cuba. The shape of the (239+240)Pu profile in the core column resembled very closely the history of atmospheric nuclear weapons' testing, and the maximum deposition in 1963 was recorded in the sediment core history. The (239+240)Pu activity concentrations in the surface layer sediments varied from 0.163 to 0.611 mBq g(-1). The inventory of (239+240)Pu was 42 ± 5.6 Bq m(-2), a value close to that expected from direct global fallout. Using the (239+240)Pu as a chronomarker the mass sedimentation rate in the area for the last 60 years was calculated, reaching values of 0.173 g cm(-2) y(-1). The mercury profile reflects the history of anthropogenic pollution in the estuary and perfectly describes the operation of the mercury-cell chlor-alkali plant, for production of NaOH, which began operations in 1980. The inventory of Hg was 2.42 ± 0.19 µg cm(-2). These results contribute to the scarce regional database for pollutants and anthropogenic radionuclides in the Caribbean marine environment, particularly in relation to (239+240)Pu.
Sujet(s)
Sédiments géologiques/composition chimique , Mercure/analyse , Plutonium/analyse , Polluants chimiques de l'eau/analyse , Polluants radioactifs de l'eau/analyse , Cuba , Contrôle des radiationsRÉSUMÉ
Levels of 137Cs in total atmospheric deposition have been measured in the Cienfuegos region (Cuba) between 1994 and 2002. Samples were collected every three months, evaporated to dryness to obtain residual samples, and measured by gamma spectrometry. The 137Cs mean concentration in total deposition was 0.24 Bq m(-2) and data ranged between < 0.05 and 0.62 Bq m(-2). Precipitation rates and raintime have proved to be the most important factors controlling the concentration and depositional flux of 137Cs in the atmosphere over Cienfuegos, showing a high correlation coefficient (R = 0.93).