RÉSUMÉ
Hypothyroidism usually presents insidiously with symptoms such as fatigue, cold intolerance, and weight gain. Less common findings include myalgia, arthralgia, and joint effusion. In the patient described here, a triathlete, interpretation of early signs and symptoms as typical tendinitis led to months of treatment failure. Considering hypothyroidism in the differential diagnosis for patients who have overuse syndromes can expedite treatment. Definitive diagnosis rests on testing of serum thyroid hormone levels. Treatment, which is usually quickly effective, consists of gradually adjusted thyroid hormone replacement.
RÉSUMÉ
Passive-protection tests were conducted in mice with antisera from rabbits immunized with formalinized or heat-killed cells or with an alcohol-precipitated fraction from the slime layer. Protection was conferred by antisera against the heatstable antigens and correlated well with agglutinin levels. Specificity was found to relate closely to the heat-stable "O" serotypes as defined by Verder and Evans.