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Eur Ann Allergy Clin Immunol ; 52(3): 104-111, 2020 05.
Article de Anglais | MEDLINE | ID: mdl-31702121

RÉSUMÉ

Summary: Objective.There are different diagnostic criteria for the diagnosis of Allergic bronchopulmonary aspergillosis (ABPA) in CF patients. In this present study we evaluated the prevalence of ABPA in Iranian CF patients by two more usual diagnostic criteria as ISHAM working criteria (A) and CF Foundation Consensus Conference criteria (B). Methods.Eighty-six CF patients were included in the study. All CF patients underwent for Aspergillus skin prick test (AST), Aspergillus-specific IgE (sIgEAf) and Aspergillus-specific IgG (sIgGAf), total IgE. The ABPA prevalence was estimated by two diagnostic criteria, (A) and (B) and compared. Results. The frequency of positive AST, total IgE, sIgEAf and sIgGAf were 47 (54.6%), 9 (10.5%), 42 (48.8%) and 67 (77.9%), respectively. The obtained rate of ABPA prevalence (10.5%) was identical in two diagnostic criteria A and B (kappa value of 1.000). Conclusions.The applied diagnostic criteria had no significant effect on the reported rate of ABPA prevalence.


Sujet(s)
Aspergillose bronchopulmonaire allergique/épidémiologie , Aspergillus fumigatus/physiologie , Mucoviscidose/épidémiologie , Adolescent , Adulte , Enfant , Enfant d'âge préscolaire , Mucoviscidose/diagnostic , Femelle , Humains , Immunoglobuline E/sang , Nourrisson , Iran/épidémiologie , Mâle , Prévalence , Tests cutanés , Jeune adulte
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