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1.
Am J Trop Med Hyg ; 97(4_Suppl): 21-27, 2017 Oct.
Article de Anglais | MEDLINE | ID: mdl-29064354

RÉSUMÉ

Before the 2010 devastating earthquake and cholera outbreak, Haiti's public health laboratory systems were weak and services were limited. There was no national laboratory strategic plan and only minimal coordination across the laboratory network. Laboratory capacity was further weakened by the destruction of over 25 laboratories and testing sites at the departmental and peripheral levels and the loss of life among the laboratory health-care workers. However, since 2010, tremendous progress has been made in building stronger laboratory infrastructure and training a qualified public health laboratory workforce across the country, allowing for decentralization of access to quality-assured services. Major achievements include development and implementation of a national laboratory strategic plan with a formalized and strengthened laboratory network; introduction of automation of testing to ensure better quality of results and diversify the menu of tests to effectively respond to outbreaks; expansion of molecular testing for tuberculosis, human immunodeficiency virus, malaria, diarrheal and respiratory diseases; establishment of laboratory-based surveillance of epidemic-prone diseases; and improvement of the overall quality of testing. Nonetheless, the progress and gains made remain fragile and require the full ownership and continuous investment from the Haitian government to sustain these successes and achievements.


Sujet(s)
Choléra , Services de laboratoire d'analyses médicales , Catastrophes , Tremblements de terre , Épidémies , Laboratoires , Santé publique , Choléra/épidémiologie , Dysenterie/diagnostic , Dysenterie/épidémiologie , Infections à VIH/diagnostic , Infections à VIH/épidémiologie , Haïti/épidémiologie , Humains , Paludisme/diagnostic , Paludisme/épidémiologie , Techniques de diagnostic moléculaire , Tuberculose/diagnostic , Tuberculose/épidémiologie
2.
Am J Trop Med Hyg ; 86(4): 573-9, 2012 Apr.
Article de Anglais | MEDLINE | ID: mdl-22492138

RÉSUMÉ

Laboratory capacity in the developing world frequently lacks quality management systems (QMS) such as good clinical laboratory practices, proper safety precautions, and adequate facilities; impacting the ability to conduct biomedical research where it is needed most. As the regulatory climate changes globally, higher quality laboratory support is needed to protect study volunteers and to accurately assess biological parameters. The University of Bamako and its partners have undertaken a comprehensive QMS plan to improve quality and productivity using the Clinical and Laboratory Standards Institute standards and guidelines. The clinical laboratory passed the College of American Pathologists inspection in April 2010, and received full accreditation in June 2010. Our efforts to implement high-quality standards have been valuable for evaluating safety and immunogenicity of malaria vaccine candidates in Mali. Other disease-specific research groups in resource-limited settings may benefit by incorporating similar training initiatives, QMS methods, and continual improvement practices to ensure best practices.


Sujet(s)
Agrément , Techniques de laboratoire clinique/normes , Laboratoires/normes , Afrique subsaharienne , Recherche biomédicale , Essais cliniques comme sujet , Test ELISA/méthodes , Humains , Laboratoires/organisation et administration , Mali , Reproductibilité des résultats , Management par la qualité/méthodes
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