RÉSUMÉ
Albert Einstein's insight that it is impossible to distinguish a local experiment in a "freely falling elevator" from one in free space led to the development of the theory of general relativity. The wave nature of matter manifests itself in a striking way in Bose-Einstein condensates, where millions of atoms lose their identity and can be described by a single macroscopic wave function. We combine these two topics and report the preparation and observation of a Bose-Einstein condensate during free fall in a 146-meter-tall evacuated drop tower. During the expansion over 1 second, the atoms form a giant coherent matter wave that is delocalized on a millimeter scale, which represents a promising source for matter-wave interferometry to test the universality of free fall with quantum matter.
Sujet(s)
Anémie/parasitologie , Moelle osseuse/parasitologie , Filarioses/parasitologie , Wuchereria bancrofti/isolement et purification , Anémie/étiologie , Anémie/anatomopathologie , Anémie aplasique/complications , Anémie aplasique/anatomopathologie , Animaux , Issue fatale , Femelle , Filarioses/complications , Filarioses/diagnostic , Hépatomégalie/étiologie , Humains , Cirrhose alcoolique/complications , Paludisme/complications , Mâle , Microfilaria , Adulte d'âge moyenRÉSUMÉ
Serum unconjugated bilirubin (UCB) levels > 205.2 mumol/L were present in 120 of 143 cases of neonatal hyperbilirubinaemia. Sixty-five per cent (78/120) cases showed bilirubin crystals in the neutrophils of Leishman's stained smears from EDTA blood. The proportion of crystal positive (CP) neutrophils was higher in septicaemia than in Haemolytic Disease of Newborn (HDN). Mortality rate was significantly higher (P < 0.001) in CP septicaemic cases when compared with those which were crystal negative (CN).
Sujet(s)
Bilirubine/analyse , Ictère néonatal/sang , Ictère néonatal/diagnostic , Granulocytes neutrophiles/composition chimique , Anémie hémolytique congénitale/sang , Anémie hémolytique congénitale/diagnostic , Anémie hémolytique congénitale/mortalité , Bilirubine/composition chimique , Bilirubine/métabolisme , Cristallisation , Femelle , Humains , Nouveau-né , Ictère néonatal/mortalité , Mâle , Pronostic , Sepsie/sang , Sepsie/mortalité , Taux de survieRÉSUMÉ
Different sugar-grafted liposomes were prepared and tested against experimental leishmaniasis in vivo using the classical drug pentamidine isethionate and its methoxy derivative. Both the drugs, when encapsulated in sugar-grafted liposomes were found to be more potent in comparison to normal liposome-encapsulated drug or to the free drug. Moreover, the mannose-grafted liposomes were adjudged to be the best in lowering of spleen parasite load in comparison with those bearing glucose or galactose. When encapsulated in mannose-grafted liposomes the therapeutic efficacy of pentamidine isethionate was found to be better than that of its methoxy derivative, although the latter seemed to be less toxic than the pentamidine isethionate itself.
