Inhalation induction with sevoflurane in adult cardiac surgery patients. A case series.

INTRODUCTION: Anesthesia induction through volatile agents is a well-established technique in several fields but not in adult patients undergoing cardiac surgery. Successful inhalation induction requires a poorly soluble, reasonably potent and minimally irritant agent, and the benefits associated to this technique include reduced incidence of hypothermia and hypotension and lower costs when compared to some intravenous anesthetics agents. METHODS: Fifty-six patients undergoing coronary artery bypass grafting were observed at the induction of general anesthesia with sevoflurane in oxygen by facial mask. All patients received 2% sevoflurane in 100% oxygen initially for 30 seconds. The inspired concentration of sevoflurane was increased to 7% until loss of consciousness and then reduced back to 2%. Next, intravenous 0.5 µg/kg sufentanil and 0.1 mg/kg pancuronium were administered. Volume-controlled ventilation was started before tracheal intubation. RESULTS: All 56 patients tolerated the inhalational induction. No patient presented signs of airway irritation. Hypotension occurred in 30 patients and was managed with low dose phenylephrine. CONCLUSIONS: This case series showed that inhalation induction is feasible and safe even in adult patients undergoing cardiac surgery.

Inhalation induction with sevoflurane in adult cardiac surgery patients. A case series

Introduction: Anesthesia induction through volatile agents is a well-established technique in several fields butnot in adult patients undergoing cardiac surgery. Successful inhalation induction requires a poorly soluble, reasonablypotent and minimally irritant agent, and the benefits associated to this technique include reduced incidenceof hypothermia and hypotension and lower costs when compared to some intravenous anesthetics agents.Methods: Fifty-six patients undergoing coronary artery bypass grafting were observed at the induction ofgeneral anesthesia with sevoflurane in oxygen by facial mask. All patients received 2% sevoflurane in 100%oxygen initially for 30 seconds. The inspired concentration of sevoflurane was increased to 7% until loss ofconsciousness and then reduced back to 2%. Next, intravenous 0.5 ìg/kg sufentanil and 0.1 mg/kg pancuroniumwere administered. Volume-controlled ventilation was started before tracheal intubation.Results: All 56 patients tolerated the inhalational induction. No patient presented signs of airway irritation.Hypotension occurred in 30 patients and was managed with low dose phenylephrine.Conclusions: This case series showed that inhalation induction is feasible and safe even in adult patientsundergoing cardiac surgery.