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1.
Acta Odontol Scand ; 83: 433-440, 2024 Jul 10.
Article de Anglais | MEDLINE | ID: mdl-38982957

RÉSUMÉ

OBJECTIVE: This study aimed to assess perceptions and actions taken by Finnish dental professionals in suspected cases of child physical abuse (CPA) and to describe changes over 10 years. MATERIAL AND METHODS: Data collected from two child abuse and neglect (CAN) surveys among Finnish dental professionals, working in public health care, covering suspicions of CPA and actions taken as well as training on CPA issues, were compared. The chi-squared (χ2) test was used to analyze associations. RESULTS: In total, 625 (2008) and 1,025 (2019) questionnaires were completed. Respondents reported that they suspected CPA more frequently in 2008 than in 2019 (21.0% vs. 8.7%, p < 0.001). Out of all respondents, 1.1% had reported their concern to the police in 2019. Worries about the report's negative consequences to the child at home (44.5% vs. 56.4%, p < 0.001) and to the informer (30.2% vs. 36.3%, p = 0.016) increased between the surveys. The proportion of respondents with previous training on CPA issues increased between the surveys (5.9% vs. 36.4%, p < 0.001). CONCLUSIONS: Recognition of CPA was low and decreased over the years. Furthermore, mandatory reporting to the police was low. Additional education on issues related to CPA is needed.


Sujet(s)
Maltraitance des enfants , Dentistes , Humains , Finlande , Maltraitance des enfants/psychologie , Enquêtes et questionnaires , Mâle , Femelle , Enfant , Dentistes/psychologie , Adulte , Adulte d'âge moyen , Attitude du personnel soignant
2.
Eur J Obstet Gynecol Reprod Biol ; 297: 106-110, 2024 Jun.
Article de Anglais | MEDLINE | ID: mdl-38608352

RÉSUMÉ

OBJECTIVE: To get information on subcutaneous extended-release buprenorphine as opioid maintenance treatment during pregnancy, we compared it to orally administered buprenorphine and buprenorphine-naloxone treatments. We hypothesized that maternal and neonatal outcomes do not differ between the treatment groups. Study design In this population-based cohort study, 60 pregnant individuals receiving non-changed opioid maintenance treatment for opioid use disorder with a buprenorphine product from the time before conception to the time after delivery and their newborns were included. They were divided into three groups based on the pharmacotherapy with subcutaneous extended-release buprenorphine, sublingual buprenorphine, or buprenorphine-naloxone. Statistical analyses were conducted using Fischer's exact tests, ANOVA tests, and Kruskal-Wallis tests. All the statistical tests were two-tailed. RESULTS: The frequency of pregnancy or delivery complications did not significantly differ between the group receiving extended-release buprenorphine and the other groups. During pregnancy, 38 % of the women used illicit drugs concomitantly, with equal frequency in the extended-release buprenorphine group and the other groups. Of the neonates, 93 % were born full-term and 90 % got at least eight Apgar points in one minute age, without significant differences between the groups (p = 0.57). The need for pharmacotherapy for neonatal opioid withdrawal syndrome was the lowest in the extended-release buprenorphine group (25 %) and highest in the sublingual buprenorphine group (67 %). Still, the difference between the treatment groups did not reach statistical significance (p = 0.17). Among all neonates, the breastfed infants were less likely to receive pharmacotherapy for withdrawal symptoms than the formula-fed ones (p = 0.048). CONCLUSIONS: Extended-release buprenorphine with steady drug concentration seems to be a promising pharmacotherapy option during pregnancy for mothers. Maternal health during pregnancy may contribute to the well-being of newborns. Larger trials are urgently needed to confirm these results..


Sujet(s)
Buprénorphine , Préparations à action retardée , Traitement de substitution aux opiacés , Troubles liés aux opiacés , Complications de la grossesse , Humains , Femelle , Grossesse , Adulte , Troubles liés aux opiacés/traitement médicamenteux , Traitement de substitution aux opiacés/méthodes , Nouveau-né , Buprénorphine/administration et posologie , Buprénorphine/usage thérapeutique , Complications de la grossesse/traitement médicamenteux , Administration par voie orale , Syndrome de sevrage néonatal/traitement médicamenteux , Issue de la grossesse , Administration par voie sublinguale , Antagonistes narcotiques/administration et posologie , Antagonistes narcotiques/usage thérapeutique , Analgésiques morphiniques/administration et posologie , Études de cohortes , Jeune adulte , Association de buprénorphine et de naloxone/administration et posologie , Association de buprénorphine et de naloxone/usage thérapeutique
3.
Acta Paediatr ; 113(7): 1579-1591, 2024 Jul.
Article de Anglais | MEDLINE | ID: mdl-38456564

RÉSUMÉ

AIM: How maternal opioid maintenance treatment (OMT) affects children is under-researched. This population-based registry study investigated child growth and somatic health following intrauterine exposure to this treatment. METHODS: Children born between 1 March 2011 and 30 May 2021 to mothers who used buprenorphine, buprenorphine-naloxone, or methadone throughout their pregnancies were followed for 2 years at the Helsinki University Hospital, Finland. Appropriate statistical tests were used to compare the treatment groups. RESULTS: Of the 67 neonates, 52% were male, 96% were born full-term and 63% were treated for neonatal opioid withdrawal syndrome. Otherwise, the children were predominantly healthy, although relatively small: 22% were small for gestational age, the methadone group children being the smallest. Foetal exposure to maternal methadone treatment, illicit drugs, hepatitis C and smoking were associated with small for gestational age; the former two were also associated with later slower growth, especially head growth and weight gain (p < 0.001). However, 29% were overweight at 2 years. CONCLUSION: Using child growth as the outcome, we found that buprenorphine-naloxone and buprenorphine-monotherapy had equal effects as forms of maternal OMT. Exposure to multiple risk factors may harm foetal and subsequent growth. We recommend long-term follow-up of children exposed to maternal OMT.


Sujet(s)
Traitement de substitution aux opiacés , Effets différés de l'exposition prénatale à des facteurs de risque , Humains , Femelle , Grossesse , Traitement de substitution aux opiacés/effets indésirables , Mâle , Nouveau-né , Facteurs de risque , Méthadone/effets indésirables , Méthadone/usage thérapeutique , Développement de l'enfant/effets des médicaments et des substances chimiques , Adulte , Enfant d'âge préscolaire , Finlande , Troubles liés aux opiacés , Buprénorphine/effets indésirables , Buprénorphine/usage thérapeutique , Nourrisson , Association de buprénorphine et de naloxone/usage thérapeutique
4.
Acta Odontol Scand ; 81(7): 534-540, 2023 Oct.
Article de Anglais | MEDLINE | ID: mdl-37155363

RÉSUMÉ

OBJECTIVE: This study aimed to assess the experiences, attitudes and knowledge of child abuse and neglect (CAN) among dentists, dental hygienists and dental nurses in Finland. MATERIAL AND METHODS: A web-based CAN survey was sent to 8500 Finnish dental professionals, covering demographic characteristics, dental education, suspicion of CAN, actions taken and reasons for inaction as well as training on CAN issues. The chi-squared (χ2) test was used to analyse associations. RESULTS: In total, 1586 questionnaires with valid data were completed. Among respondents, 25.8% had received at least some undergraduate training and 36.3% had received postgraduate training on child maltreatment issues. In addition, 43% of respondents had at least one suspicion of CAN at some point during their career. Of those, 64.3% did not refer to social services. Training positively associated with the identification of CAN and referral frequencies. Uncertainty about an observation (80.1%) and a lack of knowledge regarding procedures (43.9%) were the most frequently reported barriers. CONCLUSIONS: Finnish dental professionals need more education on child abuse and neglect issues. Competence related to CAN is fundamental to their skills given that all dental professionals regularly work with children and are obligated to report their concerns to proper authorities.


Sujet(s)
Maltraitance des enfants , Dentistes , Enfant , Humains , Finlande , Maltraitance des enfants/diagnostic , Maltraitance des enfants/prévention et contrôle , Orientation vers un spécialiste , Attitude du personnel soignant , Enquêtes et questionnaires , Déclaration obligatoire
5.
Acta Obstet Gynecol Scand ; 102(3): 313-322, 2023 03.
Article de Anglais | MEDLINE | ID: mdl-36562462

RÉSUMÉ

INTRODUCTION: Current WHO guidelines recommend using methadone or buprenorphine as maintenance treatments for maternal opioid use disorder. However, buprenorphine-naloxone, with a lower abuse risk than buprenorphine monotherapy or methadone, offers a potentially beneficial alternative, but scientific evidence on its effects on pregnancies, fetuses, and newborns is scarce. This paper compares the outcomes of the pregnancies, deliveries, and newborns of women on buprenorphine-naloxone, buprenorphine, or methadone maintenance treatments. According to the hypothesis, as a maintenance treatment, buprenorphine-naloxone does not have more adverse effects than buprenorphine, whereas methadone is more complicated. MATERIAL AND METHODS: In this population-based study, 172 pregnant women on medical-assisted treatments were followed-up at Helsinki University Women's Hospital (Finland). Women receiving the same opioid maintenance treatment from conception to delivery and their newborns were included. Consequently, 67 mother-child dyads met the final inclusion criteria. They were divided into three groups based on their opioid pharmacotherapy. The outcomes were compared among the groups and, where applicable, with the Finnish population. RESULTS: The buprenorphine-naloxone and buprenorphine groups showed similar outcomes and did not significantly differ from each other in terms of maternal health during pregnancies, deliveries, or newborns. Illicit drug use during the pregnancy was common in all groups, but in the methadone group it was most common (p = 0.001). Most neonates (96%) were born full-term with good Apgar scores. They were of relatively small birth size, with those in the methadone group tending to be the smallest. Of the neonates 63% needed pharmacological treatment for neonatal opioid withdrawal syndrome. The need was lower in the buprenorphine-based groups than in the methadone group (p = 0.029). CONCLUSIONS: Buprenorphine-naloxone seems to be as safe for pharmacotherapy for maternal opioid use disorder as buprenorphine monotherapy for both mother and newborn. Hence it could be a choice for oral opioid maintenance treatment during pregnancy, but larger studies are needed before changing the official recommendations. Women on methadone treatment carry multifactorial risks and require particularly cautious follow up. Furthermore, illicit drug use is common in all treatment groups and needs to be considered for all patients with opioid use disorder.


Sujet(s)
Buprénorphine , Substances illicites , Troubles liés aux opiacés , Complications de la grossesse , Femelle , Nouveau-né , Humains , Grossesse , Méthadone/usage thérapeutique , Buprénorphine/usage thérapeutique , Association de buprénorphine et de naloxone/usage thérapeutique , Analgésiques morphiniques/effets indésirables , Complications de la grossesse/traitement médicamenteux , Troubles liés aux opiacés/traitement médicamenteux , Troubles liés aux opiacés/épidémiologie , Parturition , Mères
6.
Acta Obstet Gynecol Scand ; 85(2): 188-94, 2006.
Article de Anglais | MEDLINE | ID: mdl-16532913

RÉSUMÉ

BACKGROUND: We investigated whether patient-controlled epidural analgesia in labor with bupivacaine and fentanyl provides more satisfaction to mothers than intermittent bolus epidural analgesia or patient-controlled epidural analgesia with plain bupivacaine. METHODS: Ninety mothers with term, uncomplicated pregnancies were randomized to receive intermittent bolus epidural analgesia (bupivacaine + fentanyl), patient-controlled epidural analgesia (bupivacaine + fentanyl), or patient-controlled epidural analgesia (bupivacaine). Pain during labor was evaluated with a visual analog scale. Obstetric and neonatal outcomes were recorded. After delivery, the mothers were given a questionnaire covering the following themes: experience of labor pain, feeling of control, fears and expectations associated with pregnancy/with delivery/with becoming a mother, as well as pain, physical condition and emotions after delivery. To elaborate on these answers, 30 mothers were further randomized to a semistructured interview, in which the same topics were discussed. The main outcome measure was maternal satisfaction. RESULTS: The intermittent bolus epidural analgesia group felt they could influence labor most (p = 0.03), and in the interview they expressed most satisfaction. In this group, the total drug utilization was smallest (bupivacaine: p <0.0001 comparing all groups, fentanyl: p = 0.03 comparing the two fentanyl-receiving groups). No differences in pain occurred. Vomiting (p = 0.04) and pruritus (p <0.0001) were more common or more severe in the groups receiving fentanyl. CONCLUSIONS: We found no advantages for patient-controlled epidural analgesia over intermittent bolus epidural analgesia in terms of maternal satisfaction.


Sujet(s)
Analgésie péridurale/méthodes , Analgésie obstétricale/méthodes , Analgésie autocontrôlée , Anesthésiques intraveineux/administration et posologie , Anesthésiques locaux/administration et posologie , Bupivacaïne/administration et posologie , Fentanyl/administration et posologie , Travail obstétrical , Satisfaction des patients , Adulte , Femelle , Humains , Entretiens comme sujet , Mesure de la douleur , Grossesse
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