A lipohydroxyacid-containing shampoo improves scalp condition and quality of life in patients with seborrheic dermatitis and light-to-moderate scalp psoriasis.

BACKGROUND: Dandruff is a common scalp disorder affecting almost half of the post-pubertal population of any ethnicity and both genders. It is one of the major reasons for patients to consult a dermatologist and it is the cause of significant psychological and social distress. AIMS: The aim of this open study was to evaluate the benefit of a 4-week treatment with a shampoo containing 0.1% lipohydroxyacid (LHA) and 1.3% salicylic acid on the scalp condition and on the quality of life of 275 volunteers with seborrheic dermatitis (SD) (n = 226) or light-to-moderate scalp psoriasis (SP) (n = 49). METHODS: The clinical benefit of the treatment was assessed by scoring the following parameters, i.e., severity of the dermatosis, scaling, itching, excoriations, and superficial burning sensation. The impact on the quality of life was assessed using the Scalpdex, a questionnaire specially developed by Chen et al. for patients with scalp dermatitis, which includes 23 questions regarding the symptoms, functioning and emotions affected by scalp dermatosis. RESULTS: The shampoo used in this study was well tolerated. After a 4-week treatment, dermatologists noticed a significant clinical improvement of all the scalp parameters evaluated (i.e., the composite lesional score was improved in 91% and 77% of the patients with SD or SP respectively). The symptoms, functioning and emotions scores of quality of life were also significantly improved in relation to the improvement of scalp condition. CONCLUSION: This study not only allowed a better understanding of the SD and SP patient's profile but also demonstrated that the shampoo evaluated is a convenient, efficient, safe, and well-tolerated cosmetic treatment of SD and light-to-moderate SP improving greatly the quality of life of the treated patients.

Microinjerto de cabellos y de vellos: sus múltiples indicaciones / Vellus and hair micrografts: Indications

El progreso de los tratamientos actuales, permite proponer una terapéutica médica o quirúrgica adaptada a la importancia de la caída del cabello y de la calvicie para cada paciente. El microinjerto de unidades foliculares y de mini microinjertos es un progreso técnico fundamental. Esta técnica, permite una recuperación capilar definitiva de las calvicies de ciertas regiones pilosas del hombre y de la mujer y aporta de manera simple e indolora, cabellos donde la emergencia por grupos de uno a tres es perfectamente natural. La diferencia entre los receptores androgénicos de las regiones occipitales y de las otras regiones, explica el carácter definitivo del crecimiento de los cabellos reimplantados. El grado de calvicie de una alopecia androgenética masculina o femenina puede ser evaluado de acuerdo a una clasificación estática (Hamilton, Ludwig) o ser medido y seguido con más precisión, con una clasificación dinámica plurifactorial (Bouhanna). Todas ías indicaciones actuales de microinjertos son: - Las alopecias androgenéticas masculinas de los estadios III a VII - Las alopecias androgenéticas femeninas de los estadios I a III - El llenado de las entradas en los transexuales - Las alopecias cicatriciales - Las alopecias de las cejas - Las cicatrices de la barba y del bigote - La alopecia del pubis

Advances in treatments of androgenetic alopecia have led to the development of novel medical or surgical therapies adapted to the severity of hair loss and balding. Follicular units or tiny micrograft hair transplants are a fundamental technical progress. This technique leads to the simple and painless permanent restoration of hair in male and female baldness It provides the patient with a group of 1 to 3 hairs, emerging from a single orifice. The difference between androgenetic receptors of occipital areas and those of other areas explains the permanent nature of the implanted hairs growth. The degree of male or female androgenetic alopecia can be determined according to Hamilton's static classification or Ludwig's Classification, or it can be measured and monitored more accurately with Bouhanna's Dynamic Multifactorial Classification. The current indications of micrograft transplantation are: - Male androgenetic alopecia (Hamilton 111 to VII) - Female androgenetic alopecia (Ludwig 1 to 111) - Frontal recession hair transplantation in transsexuals - Cicatricial alopecia - Alopecia of the eyebrows - Bald spots of the beard and moustache - Alopecia of the pubis