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5.
Front Nutr ; 10: 1156995, 2023.
Article de Anglais | MEDLINE | ID: mdl-37215211

RÉSUMÉ

Background: Obesity is complicated by low-grade chronic inflammation characterised by increases in inflammatory proteins and cells in peripheral blood. It has been known that omega-3 fatty acids (FA) like eicosapentaenoic (EPA) and docosahexaenoic (DHA) could modulate the inflammatory process and improve metabolic markers. Objective: This study aimed to determine the effect of high-dose omega-3 FA on metabolic and inflammatory markers among patients with obesity and healthy volunteers. Methods: This prospective study included 12 women with obesity (body mass index [BMI] ≥ 35.0 kg/m2) and 12 healthy women (BMI < 24.0 kg/m2) who were supplemented with a dose of 4.8 g/day (3.2 g EPA plus 1.6 g DHA) for 3 months followed by no treatment for 1 month. Plasma metabolic and inflammatory markers and levels of mRNA transcripts of CD4+ T lymphocyte subsets were determined monthly. Results: None of the participants exhibited changes in weight or body composition after study completion. EPA and DHA supplementation improved metabolic (insulin, Homeostatic Model Assessment of Insulin Resistance [HOMA-IR], triglyceride [TG]/ high-density lipoprotein [HDL] ratio, TG, and arachidonic acid [AA]/EPA ratio) and tumor necrosis factor-alpha (TNF-α). Moreover, the levels of mRNA transcripts of T CD4+ lymphocyte subsets (TBX21, IFNG, GATA-3, interleukin [IL]-4, FOXP3, IL-10 IL-6, and TNF-α), were down-regulated during the intervention phase. After 1 month without supplementation, only insulin, HOMA-IR and the mRNA transcripts remained low, whereas all other markers returned to their levels before supplementation. Conclusion: Supplementation with high-dose omega-3 FAs could modulate metabolism and inflammation in patients with obesity without weight loss or changes in body composition. However, these modulatory effects were ephemeral and with clear differential effects: short-duration on metabolism and long-lasting on inflammation.

8.
Diabetes Care ; 46(Suppl 1): S191-S202, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507634

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète , Endocrinologie , Insuffisance rénale chronique , Humains , Norme de soins , Diabète/thérapie , Insuffisance rénale chronique/thérapie , Sociétés médicales , Normes de référence
9.
Diabetes Care ; 46(Suppl 1): S41-S48, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507633

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète de type 2 , Diabète , Endocrinologie , Humains , Diabète de type 2/prévention et contrôle , Norme de soins , Comorbidité , Diabète/thérapie , Sociétés médicales , Normes de référence
10.
Diabetes Care ; 46(Suppl 1): S111-S127, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507635

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète , Endocrinologie , Humains , Norme de soins , Diabète/thérapie , Sociétés médicales , Normes de référence
11.
Diabetes Care ; 46(Suppl 1): S158-S190, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507632

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Maladies cardiovasculaires , Diabète , Endocrinologie , Humains , Maladies cardiovasculaires/thérapie , Norme de soins , Diabète/thérapie , Sociétés médicales , Normes de référence
12.
Diabetes Care ; 46(Suppl 1): S203-S215, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507636

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète , Endocrinologie , Neuropathies périphériques , Rétinopathies , Humains , Norme de soins , Diabète/thérapie , Sociétés médicales , Normes de référence
13.
Diabetes Care ; 46(Supple 1): S10-S18, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507639

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète , Endocrinologie , Humains , Norme de soins , Amélioration de la qualité , Diabète/thérapie , Sociétés médicales , Normes de référence
14.
Diabetes Care ; 46(Suppl 1): S128-S139, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507637

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète de type 2 , Diabète , Endocrinologie , Humains , Diabète de type 2/prévention et contrôle , Norme de soins , Obésité/prévention et contrôle , Diabète/thérapie , Sociétés médicales , Normes de référence
15.
Diabetes Care ; 46(Suppl 1): S216-S229, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507638

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète , Endocrinologie , Humains , Sujet âgé , Norme de soins , Diabète/thérapie , Sociétés médicales , Normes de référence
17.
Diabetes Care ; 46(Suppl 1): S279-S280, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507643

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète , Endocrinologie , Humains , Norme de soins , Diabète/thérapie , Sociétés médicales , Normes de référence
18.
Diabetes Care ; 46(Suppl 1): S267-S278, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507644

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète , Endocrinologie , Humains , Norme de soins , Diabète/thérapie , Hôpitaux , Sociétés médicales , Normes de référence
19.
Diabetes Care ; 46(Suppl 1): S230-S253, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507640

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète , Endocrinologie , Enfant , Adolescent , Humains , Norme de soins , Diabète/thérapie , Sociétés médicales , Normes de référence
20.
Diabetes Care ; 46(Suppl 1): S254-S266, 2023 01 01.
Article de Anglais | MEDLINE | ID: mdl-36507645

RÉSUMÉ

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.


Sujet(s)
Diabète , Endocrinologie , Grossesse , Femelle , Humains , Norme de soins , Diabète/thérapie , Sociétés médicales , Normes de référence
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