RÉSUMÉ
Objective To compare the recurrence rate and long-term follow-up angiographic findings between stent-assisted coil embolization and simple coil embolization in treating large and giant intracranial aneurysms.Methods The clinical data and imaging materials of a total of 90 patients with large and giant intracranial aneurysms (>10 mm,91 aneurysms in total),who were admitted to authors' hospital during the period from January 2004 to January 2016 to receive interventional embolization therapy,were retrospectively analyzed.Of the 90 patients,52 patients (52 lesions in total) received simple coil embolization (SCE group)and 38 patients (39 lesions in total) received stent-assisted coil embolization (SACE group).Postoperative recurrence rates of aneurysm were compared between the two groups,and recurrence risk factors were analyzed.Results The whole postoperative recurrence rate of aneurysm and re-treatment rate were 38.5%(35/91) and 20.9%(19/91) respectively;the recurrence rate and re-treatment rate of SACE group were 35.9% (14/39) and 17.9% (7/39) respectively,while those of SCE group were 40.4% (21/52) and 23.1% (12/52) respectively;the differences between the two groups were not statistically significant (P>0.05).Multivariate logistic regression indicated that the recurrence risk factors of large or giant intracranial aneurysms included rupture of aneurysm (OR=0.284,95%CI=0.083-0.978,P=0.046),simple coil embolization (OR=5.03,95% CI=1.04-24.44,P=0.045),concurrent hypertension (OR =0.13,95% CI=0.036-0.51,P=0.003)and long time after operation (OR=1.002,95%CI=1.001-1.003,P=0.002).Conclusion Compared with simple coil embolization,stent-assisted coil embolization can reduce the recurrence rate of aneurysm.Rupture of aneurysm,simple coil embolization,long time after operation and concurrent hypertension are independent risk factors for recurrence of aneurysm after transcatheter arterial embolization.