RÉSUMÉ
Background: The obstructive sleep apnea syndrome (OSA) is a highly prevalent condition. In Spain and other countries, only 5%-9% of patients with OSA have been diagnosed and treated. The lack of accessibility to diagnosis is considered the main cause of this situation through easy-to-use screening instruments, it is necessary to check their validity and reliability in the context where they are to be used. Objective: To validate the Spanish translation of the Berlin questionnaire for screening for moderate or severe OSA in patients aged 40 years or more detected in primary care. Methods: A descriptive observational study, with a first qualitative phase of transcultural adaptation to Spanish using the translation-back-translation method. Setting: primary care level of the Spanish National Health System. A total of 255 patients recruited from 7 healthcare centers completed the study. The Berlin questionnaire was administered to the recruited patients, and subsequently, a respiratory polygraphy was performed to confirm the diagnosis of OSA. The concurrent criterion validity of the questionnaire and its reliability in terms of internal consistency and reproducibility (intra-observer agreement) were analyzed. Results: The patients' mean age was 54.76 years (SD: 6.57; 95% CI: 53.53-54.99), and 54.12% were men (95% CI: 47.96-60.27). We found that 61.57% (95% CI: 55.57-67.57) presented OSA (apnea-hypopnea index-AHI >5), and 45.5% (95% CI: 17.05-57.92) presented moderate or severe (AHI >15) OSA. The Berlin questionnaire, with a cut-off point of 4.5, showed a sensitivity of 76.77% (95% CI: 67.94-85.59), a specificity of 74.49% (95% CI: 65.35-83.63), a positive predictive value of 75.25% (95% CI: 66.34-84.16), a negative predictive value of 76.04% (95% CI: 66.98-85.10), and an area under the curve of 0.786 (95% CI: 0.721-0.851). Cronbach's alpha coefficient was 0.730 (95% CI: 0.668-0.784), and the Kappa index was 0.739 (95% CI, 0.384-1.000). Conclusion: The Spanish adaptation of the Berlin questionnaire has good validity and reliability as a test for the diagnostic screening of moderate or severe OSA in patients aged 40 years or older. The findings of our study confirm that primary care physicians should use such screening tools to predict OSA.
RÉSUMÉ
Rationale: Sleep apnea-hypopnea syndrome (OSA) is a highly prevalent disease and has been related to cardiovascular diseases and occupational and traffic accidents. Currently, it is estimated that there is a significant underdiagnosis of OSA, mainly due to the difficulty accessing the tests for that purpose. Objective: To determine the usefulness of the Spanish version of the STOP-Bang questionnaire (SBQ) for screening for moderate or severe OSA in the adult population attending primary care. Methods: A descriptive observational multicenter study was conducted. Through an opportunistic search, (patients over 18 years old), were recruited in seven primary care centers. The SBQ was applied to them and home respiratory polygraphy (HRP) was subsequently performed to confirm the diagnosis of OSA. The criterion validity of the SBQ was analyzed, comparing the score obtained by the SBQ with the apnea-hypopnea index (AHI) obtained by RP, establishing the diagnosis of OSA for an AHI>5. The reliability of the questionnaire was evaluated. Results: A total of 255 subjects, 54.1% men, with a mean age of 54.76 ± 10 years, were recruited in the study. The results showed that 61.57% (95% Confidence Interval: 55.57-67.57) of the subjects presented OSA, presenting 22.75% (17.57-57.92) a mild OSA (530) (11.54-20.62). The Kuder and Richardson coefficient was 0.623 (0.335-0.788) and Cohen's Kappa coefficient was 0.871 (0.520-1.00; p < 0.001). For moderate/severe OSA screening (AHI>15) the SBQ obtained an ROC curve of 0.769 (0.704-0.833) that with an optimal cutoff of 3, achieved a sensitivity of 84.85% (77.28-92.42) and a specificity of 55.10% (44.74-65.46). Conclusions: The SBQ is very effective for detecting moderate/severe OSA. Its psychometric properties are similar to those obtained in studies on other populations. Because of its ease of use, the SBQ is a very useful tool for primary health care professionals.
Sujet(s)
Syndrome d'apnées obstructives du sommeil , Adolescent , Adulte , Femelle , Humains , Mâle , Adulte d'âge moyen , Polysomnographie/méthodes , Soins de santé primaires , Reproductibilité des résultats , Syndrome d'apnées obstructives du sommeil/diagnostic , Enquêtes et questionnairesRÉSUMÉ
OBJECTIVE: The goal of this study was to assess the effectiveness of opportunistic screening through pulse palpation in the early detection of atrial fibrillation in subjects aged≥65 years versus detection through an active search for patients with symptoms and/or complications and sequelae associated. MATERIAL AND METHODS: This was a cluster randomized controlled trial performed in 48 primary care centers of the Spanish National Healthcare System. A total of 368 physicians and nurses were randomized. The researchers in the experimental group (EG) performed opportunistic screening for auricular fibrillation, whereas the researchers in the control group (CG) actively searched for symptomatic patients. An ECG was performed on patients found to have an irregular heartbeat to confirm the diagnosis of auricular fibrillation. RESULTS: A total of 5,465 patients with a mean age of 75.61 years were recruited for the EG, and 1,525 patients with a mean age of 74.07 years were recruited for the CG. Of these, 58.6% were female, without significant differences between groups. Pulse was irregular in 4.3 and 15.0% of the patients in the EG and the CG, respectively (P<.001). A total of 164 new cases of atrial fibrillation were detected (2.3%), 1.1% in the EG and 6.7% in the CG (adjusted OR: 0.29; 95% CI 0.18-0.45). CONCLUSIONS: Case finding for atrial fibrillation in patients aged≥65 years with symptoms or signs suggestive of atrial fibrillation is a more effective strategy than opportunistic screening through pulse palpation in asymptomatic patients. TRIAL REGISTRATION: The trial is registered in ClinicalTrials.gov (NCT01291953; February 8, 2011).
Sujet(s)
Fibrillation auriculaire/diagnostic , Dépistage de masse/méthodes , Sujet âgé , Sujet âgé de 80 ans ou plus , Diagnostic précoce , Électrocardiographie , Femelle , Rythme cardiaque , Humains , Modèles logistiques , Mâle , Analyse multifactorielle , Palpation , Soins de santé primairesRÉSUMÉ
Objetivo: El objetivo de este estudio fue evaluar la eficacia del cribado oportunista a través de la palpación del pulso para la detección de fibrilación auricular en sujetos asintomáticos de edad ≥ 65 años frente a la búsqueda activa de pacientes de la misma edad con síntomas y/o complicaciones y secuelas asociadas. Material y métodos: Se realizó un ensayo clínico controlado aleatorizado por clúster en 48 centros de atención primaria del Sistema Nacional de Salud español. Se aleatorizó a un total de 368 médicos y enfermeras. Los investigadores del grupo experimental (GE) realizaron el cribado oportunista para la fibrilación auricular, mientras que los investigadores del grupo control (GC) realizaron una búsqueda activa en pacientes sintomáticos. Se realizó un ECG en los pacientes que tenían un pulso irregular para confirmar el diagnóstico de fibrilación auricular. Resultados: Un total de 5.465 pacientes con una edad media de 75,61 fueron seleccionados para el GE y 1.525 pacientes para el GC, con una edad media de 74,07 años. El 58,6% eran mujeres, sin diferencias significativas entre los grupos. El pulso era irregular en el 4,3 y el 15% de los pacientes del GE y el GC, respectivamente (p < 0,001). Se detectaron un total de 164 nuevos casos de fibrilación auricular (2,3%), el 1,1% en el GE y el 6,7% en el GC (OR ajustada 0,29; IC 95% 0,18-0,45). Conclusiones: La búsqueda activa, a través de la palpación del pulso, de fibrilación auricular en pacientes de edad ≥ 65 años con síntomas o signos indicativos es una estrategia más eficaz que el cribado oportunista en pacientes asintomáticos. Registro del ensayo clínico: Registrado en ClinicalTrials.gov (NCT01291953; 8 de febrero de 2011) (AU)
Objective: The goal of this study was to assess the effectiveness of opportunistic screening through pulse palpation in the early detection of atrial fibrillation in subjects aged ≥ 65 years versus detection through an active search for patients with symptoms and/or complications and sequelae associated. Material and methods: This was a cluster randomized controlled trial performed in 48 primary care centers of the Spanish National Healthcare System. A total of 368 physicians and nurses were randomized. The researchers in the experimental group (EG) performed opportunistic screening for auricular fibrillation, whereas the researchers in the control group (CG) actively searched for symptomatic patients. An ECG was performed on patients found to have an irregular heartbeat to confirm the diagnosis of auricular fibrillation. Results: A total of 5,465 patients with a mean age of 75.61 years were recruited for the EG, and 1,525 patients with a mean age of 74.07 years were recruited for the CG. Of these, 58.6% were female, without significant differences between groups. Pulse was irregular in 4.3 and 15.0% of the patients in the EG and the CG, respectively (P < .001). A total of 164 new cases of atrial fibrillation were detected (2.3%), 1.1% in the EG and 6.7% in the CG (adjusted OR: 0.29; 95% CI 0.18-0.45). Conclusions: Case finding for atrial fibrillation in patients aged ≥ 65 years with symptoms or signs suggestive of atrial fibrillation is a more effective strategy than opportunistic screening through pulse palpation in asymptomatic patients. Trial registration: The trial is registered in ClinicalTrials.gov (NCT01291953; February 8, 2011) (AU)
Sujet(s)
Humains , Fibrillation auriculaire/épidémiologie , Dépistage de masse/méthodes , Troubles du rythme cardiaque/épidémiologie , Échantillonnage en Grappes , Maladies asymptomatiques/épidémiologie , Études cas-témoins , PoulsRÉSUMÉ
En los últimos años, los cambios en la demanda de asistencia sanitaria relacionada con la patología mamaria, y en concreto con el cáncer de mama, unidos a las nuevas tendencias diagnósticas y terapéuticas, han impulsado el desarrollo de equipos multidisciplinarios dedicados a esta enfermedad. En la mayoría de los centros sanitarios que atienden patología mamaria se han creado unidades multidisciplinarias de mama siguiendo las directrices de determinadas instituciones y sociedades científicas. En el presente trabajo se revisan las recomendaciones más importantes al respecto, se valoran la experiencia y los aspectos organizativos que han permitido adaptarse a esta nueva situación, y se plantean estrategias futuras (AU)
In recent years, demand changes in health care related to breast disease, and in particular with breast cancer, together with new diagnostic and therapeutic trends, have driven the development of multidisciplinary teams dedicated to this condition. Multidisciplinary units for treating breast diseases have been established in most of health centers under the guidance of certain institutions and scientific societies. This paper reviews the most important recommendations for these units, and evaluates the experience and organizational aspects that have allowed them to adapt to this new situation, and proposes future strategies (AU)