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1.
J Drugs Dermatol ; 20(3): 326-334, 2021 03 01.
Article de Anglais | MEDLINE | ID: mdl-33683073

RÉSUMÉ

BACKGROUND: Lipedema is a chronic, progressive disease that occurs almost exclusively in women and leads to pathological, painful fat growths at the extremities. Only symptomatic therapy can be offered since the etiology of the disease has not yet been clarified. Liposuction in tumescent anesthesia has established itself as a surgical treatment method of choice. The complication rate associated with the procedure and the pharmacological course and safety of treatment in patients with lipedema has not yet been sufficiently studied. The aim of the study was to broaden the evidence on the safety of ambulatory high-volume liposuction in tumescent anesthesia in lipedema patients. Influencing factors of patients (weight, fat content, comorbidities) or the process technique (drug administration, volume of aspirates) should be investigated on the safety and risks of tumescent anesthesia. This was a retrospective data analysis in which data from 27 patients (40 liposuction procedures) treated at the Sandhofer and Barsch lipedema center between 2016 and 2018 were evaluated. The liposuctions were carried out in tumescent anesthesia and using a Power-Assisted Liposuction system. Clinical examinations and regular blood samples were carried out before the procedure, intra- and postoperatively. The procedures lasted an average of 118 minutes and an average of 6111 ml of aspirate was removed. For tumescent anesthesia, patients were given an average lidocaine dose of 34.23 mg/kg body weight and an epinephrine dose of 0.11 mg/kg body weight. No relevant complications associated with drug side effects, hypovolemia or hypervolemia or blood loss were detected. Liposuction under high volume tumescent anesthesia for the treatment of lipedema patients is, even for major intervention, a safe procedure. J Drugs Dermatol. 2021;20(3):326-334. doi:10.36849/JDD.5828.


Sujet(s)
Procédures de chirurgie ambulatoire/effets indésirables , Anesthésie locale/méthodes , Lipectomie/effets indésirables , Lipoedème/chirurgie , Douleur postopératoire/diagnostic , Adulte , Procédures de chirurgie ambulatoire/instrumentation , Procédures de chirurgie ambulatoire/méthodes , Anesthésie locale/effets indésirables , Anesthésiques locaux/administration et posologie , Anesthésiques locaux/effets indésirables , Épinéphrine/administration et posologie , Épinéphrine/effets indésirables , Humains , Injections sous-cutanées , Lidocaïne/administration et posologie , Lidocaïne/effets indésirables , Lipectomie/instrumentation , Lipectomie/méthodes , Adulte d'âge moyen , Mesure de la douleur/statistiques et données numériques , Douleur postopératoire/prévention et contrôle , Études rétrospectives , Résultat thérapeutique
2.
Dermatol Surg ; 46(2): 220-228, 2020 02.
Article de Anglais | MEDLINE | ID: mdl-31356433

RÉSUMÉ

BACKGROUND: Lipedema is a chronic, progressive disorder of subcutaneous adipose tissue that usually affects the lower extremities of women. Also known as "two-body syndrome," the fat accumulations in lipedema are unsightly and painful. The disorder is well-known in Europe but is largely unrecognized and underdiagnosed in the United States. OBJECTIVE: To hold the First International Consensus Conference on Lipedema with the purpose of reviewing current European guidelines and the literature regarding the long-term benefits that have been reported to occur after lymph-sparing liposuction for lipedema using tumescent local anesthesia. METHODS: International experts on liposuction for lipedema were convened as part of the First International Congress on Lipedema in Vienna, Austria, June 9 to 10, 2017. RESULTS: Multiple studies from Germany have reported long-term benefits for as long as 8 years after liposuction for lipedema using tumescent local anesthesia. CONCLUSION: Lymph-sparing liposuction using tumescent local anesthesia is currently the only effective treatment for lipedema.


Sujet(s)
Anesthésie locale/méthodes , Lipectomie/normes , Lipoedème/chirurgie , Douleur liée aux interventions/prévention et contrôle , Guides de bonnes pratiques cliniques comme sujet , Anesthésiques locaux/administration et posologie , Conférences de consensus comme sujet , Évolution de la maladie , Femelle , Humains , Lidocaïne/administration et posologie , Lipectomie/effets indésirables , Lipectomie/méthodes , Lipoedème/diagnostic , Lipoedème/étiologie , Adulte d'âge moyen , Douleur liée aux interventions/étiologie , Planification des soins du patient/normes , Soins postopératoires/méthodes , Soins postopératoires/normes , Graisse sous-cutanée , Résultat thérapeutique
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