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1.
Article de Anglais | MEDLINE | ID: mdl-39200686

RÉSUMÉ

Food insecurity increased during the COVID-19 pandemic, but the impact varied across different age groups during the prolonged public health emergency. This study sought to describe national food insecurity prevalence by adult age group at multiple stages of the pandemic and explore differences by demographic characteristics. Data were from the nationally representative US Census Bureau's Household Pulse Survey from April 2020 to May 2023 (N = 4,153,462). Locally weighted scatterplot smoothing (LOESS) regression analysis identified change points in food insecurity trends, segmenting the timeline into three periods: (1) April 2020-March 2021, (2) April 2021-May 2022, and (3) June 2022-May 2023. Logistic regression models examined associations between age, time period, and self-reported household food insecurity; covariates included demographics, socioeconomic status, household structure, and food support program usage. Overall, 9.3% of respondents experienced food insecurity, ranging from 3.5% among those aged ≥75 to 12.2% for ages 35-44 years. Significant interaction between age group and time period indicated inconsistency in the age-food insecurity association during the pandemic (p < 0.001). From Period 1 to 3, the proportion of food-insecure adults aged ≥65 rose from 9.2% to 13.9%. Across all age groups, higher odds of food insecurity were found among Black, Hispanic/Latino, or Other/Multiracial respondents; those with less than a Bachelor's degree; those with incomes below USD 35,000; those unemployed for reasons other than retirement; and non-homeowners (p < 0.001). The results show that trends and characteristics associated with food insecurity varied across age groups and time periods. Continuous monitoring of food insecurity during emergencies is critical to identify vulnerable populations and timely interventions.


Sujet(s)
COVID-19 , Insécurité alimentaire , Humains , COVID-19/épidémiologie , États-Unis/épidémiologie , Adulte , Adulte d'âge moyen , Sujet âgé , Femelle , Mâle , Jeune adulte , Facteurs âges , Adolescent , Pandémies , Facteurs socioéconomiques , SARS-CoV-2
2.
Future Oncol ; : 1-12, 2024 Jul 29.
Article de Anglais | MEDLINE | ID: mdl-39072442

RÉSUMÉ

Aim: To estimate projected US-based cost and time burden for patients with myelofibrosis and anemia treated with momelotinib compared with danazol. Methods: Cost and time burden were calculated based on the transfusion status of patients in the MOMENTUM trial and estimates extracted from previous studies. Results: Reductions in transfusion associated with momelotinib are projected to result in cost and time savings compared with danazol in transfusion-dependent and transfusion-independent/requiring patients with myelofibrosis, respectively: annual medical costs ($53,143 and $46,455 per person), outpatient transfusion costs ($42,021 and $8,370 per person) and annual time savings (173 and 35 h per person). Conclusion: Fewer transfusions with momelotinib are projected to result in cost and time savings in patients with myelofibrosis and anemia compared with danazol.


Estimated cost & time savings in patients with the blood cancer myelofibrosisMyelofibrosis is a rare blood cancer often associated with bone marrow damage, too few of some types of blood cells and symptoms including tiredness, night sweating, itching and feelings of fullness and pain because of increased spleen size. Patients with anemia (too few red blood cells) may require regular blood transfusions and this is one sign that myelofibrosis is getting worse. MOMENTUM was a Phase III clinical trial showing that the drug momelotinib was safe and effective in patients with myelofibrosis who were previously treated with a type of drug called a JAK inhibitor. In particular, the trial showed that momelotinib reduced the need for transfusions compared with danazol, another drug typically used to treat patients with anemia. Based on this transfusion information from MOMENTUM and other publicly available information about estimated medical costs and patients' time spent in receiving transfusions, the analysis described here shows that a reduction in the number of transfusions with momelotinib compared with danazol is estimated to lead to cost savings as well as reduced patient time spent in transfusion-related travel, preparing and waiting for transfusions and receiving and recovering from transfusions.

3.
Infect Dis Ther ; 13(5): 965-990, 2024 May.
Article de Anglais | MEDLINE | ID: mdl-38589763

RÉSUMÉ

Human papillomavirus (HPV) is a common sexually transmitted virus that can cause cervical cancer and other diseases. Dynamic transmission models (DTMs) have been developed to evaluate the health and economic impacts of HPV vaccination. These models typically include many parameters, such as natural history of the disease, transmission, demographic, behavioral, and screening. To ensure the accuracy of DTM projections, it is important to parameterize them with the best available evidence. This study aimed to identify and synthesize data needed to parametrize DTMs on the natural history of HPV infection and related diseases. Parameters describing data of interest were grouped by their anatomical location (genital warts, recurrent respiratory papillomatosis, and cervical, anal, vaginal, vulvar, head and neck, and penile cancers), and natural history (progression, regression, death, cure, recurrence, detection), and were identified through a systematic literature review (SLR) and complementary targeted literature reviews (TLRs). The extracted data were then synthesized by pooling parameter values across publications, and summarized using the range of values across studies reporting each parameter and the median value from the most relevant study. Data were extracted and synthesized from 223 studies identified in the SLR and TLRs. Parameters frequently reported pertained to cervical cancer outcomes, while data for other anatomical locations were less available. The synthesis of the data provides a large volume of parameter values to inform HPV DTMs, such as annual progression rates from cervical intraepithelial neoplasia (CIN) 1 to CIN 2+ (median of highest quality estimate 0.0836), CIN 2 to CIN 3+ (0.0418), carcinoma in situ (CIS) 2 to local cancer+ (0.0396), and regional to distant cancer (0.0474). Our findings suggest that while there is a large body of evidence on cervical cancer, parameter values featured substantial heterogeneity across studies, and further studies are needed to better parametrize the non-cervical components of HPV DTMs.

4.
Curr Pharm Teach Learn ; 15(7): 693-698, 2023 07.
Article de Anglais | MEDLINE | ID: mdl-37394356

RÉSUMÉ

BACKGROUND AND PURPOSE: To describe the development and implementation of professional and personal identity formation content in a virtual pre-health pathway program. EDUCATIONAL ACTIVITY AND SETTING: Content within a six-week pre-health program for underrepresented and/or disadvantaged college students was redesigned to a virtual format with enhanced focus on professional and personal identity formation. Sessions on personal identity formation were also enhanced through a partnership with local mental health clinicians specializing in trauma-informed care and culturally relevant practices and strategies. FINDINGS: The 2020 and 2021 programs were restructured to include pharmacy professional identity formation content around the following weekly themes: Roadmap to Pharmacy, What Does it Mean to be a Pharmacist?, Expanding Knowledge of Pharmacy, Gaining Insight and Dispelling Myths, Practicing Knowledge and Exploration, and Moving Forward. These pre-pharmacy components emphasized diversity of career paths, pharmacy-based clinical services, and the pharmacist's role in promoting health equity. Overarching components of interprofessional collaboration coupled with health policy applications further emphasized the professional identity of a pharmacist in the collaborative design and delivery of health care. New personal identity formation sessions were implemented in tandem with this content and centering around the following themes: Supporting Scholars in Self-Authorship, Building a Community among Peers, and Strategies for Coping in Times of Challenge. SUMMARY: This project has the potential to serve as a model for the implementation of both personal and professional identity formation initiatives at other programs to promote pharmacy as a desirable and attainable career to pre-health students.


Sujet(s)
Services pharmaceutiques , Pharmacie , Étudiant pharmacie , Humains , Cadre intersectionnel , Pharmaciens
5.
Article de Anglais | MEDLINE | ID: mdl-37174224

RÉSUMÉ

Central Java, Indonesia, is prone to river and coastal flooding due to climate changes and geological factors. Migration is one possible adaptation to flooding, but research is limited due to lack of longitudinal spatially granular datasets on migration and metrics to identify flood-affected households. The available literature indicates social and economic barriers may limit mobility from flood prone areas. The Indonesian Family Life Survey (IFLS) provides self-reported data on household experiences with natural disasters among 1501 Central Java households followed over two waves (2007 and 2014). We examined how the severity of flooding, defined by household-level impacts captured by the IFLS (death, injury, financial loss, or relocation of a household member), influenced the extent of household movement in Central Java using a generalized ordered logit/partial proportional odds model. Households severely impacted by floods had 75% lower odds of moving farther away compared to those that did not experience floods. The most severely impacted households may be staying within flood-affected areas in Central Java. Public health, nutrition, and economic surveys should include modules focused on household experiences, impacts, and adaptations to facilitate the study of how climate changes are impacting these outcomes.


Sujet(s)
Catastrophes , Inondations , Humains , Indonésie , Caractéristiques familiales , Acclimatation
6.
Sensors (Basel) ; 23(8)2023 Apr 12.
Article de Anglais | MEDLINE | ID: mdl-37112248

RÉSUMÉ

The inspection of nuclear power plants is an essential process that occurs during plant outages. During this process, various systems are inspected, including the reactor's fuel channels to ensure that they are safe and reliable for the plant's operation. The inspection of Canada Deuterium Uranium (CANDU®) reactor pressure tubes, which are the core component of the fuel channels and house the reactor fuel bundles, is performed using Ultrasonic Testing (UT). Based on the current process that is followed by Canadian nuclear operators, the UT scans are manually examined by analysts to locate, measure, and characterize pressure tube flaws. This paper proposes solutions for the auto-detection and sizing of pressure tube flaws using two deterministic algorithms, the first uses segmented linear regression, while the second uses the average time of flight (ToF) within ±σ of µ. When compared against a manual analysis stream, the linear regression algorithm and the average ToF achieved an average depth difference of 0.0180 mm and 0.0206 mm, respectively. These results are very close to the depth difference of 0.0156 mm when comparing two manual streams. Therefore, the proposed algorithms can be adopted in production, which can lead to significant cost savings in terms of time and labor.

7.
Sci Total Environ ; 873: 162315, 2023 May 15.
Article de Anglais | MEDLINE | ID: mdl-36805065

RÉSUMÉ

Public climatic data are rapidly growing in volume and complexity at global and national scales but these data remain underutilized for vulnerability assessment. We aim to explore how flood records from Dartmouth Flood Observatory, a global flood monitoring database, can be linked with a national disaster database maintained by the Indonesian National Board for Disaster Management, to aid local vulnerability assessment in Indonesia. We focused on physical damage to structures and agricultural crops from flooding and examined spatiotemporal patterns of a vulnerability metric derived from principal component analysis. We identified the most vulnerable areas based on emerging hot spot analysis and detected sporadic hotspots (i.e. on again then off again) of flooding in Jakarta and West Java. Using our derived metric, we identified oscillating cold spots (i.e. a cold spot that was previously a hot spot) of vulnerability in Banten, Jakarta, West Java, and Central Java. The detection of nonhomogeneous spatiotemporal trends in flooding and vulnerability demonstrate potential usability of public climate data and help to outline directions for novel research.

8.
Article de Anglais | MEDLINE | ID: mdl-35564342

RÉSUMÉ

Earlier identification and removal of contaminated food products is crucial in reducing economic burdens of foodborne outbreaks. Recalls are a safety measure that is deployed to prevent foodborne illnesses. However, few studies have examined temporal trends in recalls or compared risk factors between non-recall and recall outbreaks in the United States, due to disparate and often incomplete surveillance records in publicly reported data. We demonstrated the usability of the electronic Foodborne Outbreak Reporting System (eFORS) and National Outbreak Reporting System (NORS) for describing temporal trends and outbreak risk factors of food recalls in 1998−2019. We examined monthly trends between surveillance systems by using segmented time-series analyses. We compared the risk factors (e.g., multistate outbreak, contamination supply chain stage, pathogen etiology, and food products) of recalls and non-recalls by using logistic regression models. Out of 22,972 outbreaks, 305 (1.3%) resulted in recalls and 9378 (41%) had missing recall information. However, outbreaks with missing recall information decreased at an accelerating rate of ~25%/month in 2004−2009 and at a decelerating rate of ~13%/month after the transition from eFORS to NORS in 2009−2019. Irrespective of the contaminant etiology, multistate outbreaks according to the residence of ill persons had odds 11.00−13.50 times (7.00, 21.60) that of single-state outbreaks resulting in a recall (p < 0.001) when controlling for all risk factors. Electronic reporting has improved the availability of food recall data, yet retrospective investigations of historical records are needed. The investigation of recalls enhances public health professionals' understanding of their annual financial burden and improves outbreak prediction analytics to reduce the likelihood and severity of recalls.


Sujet(s)
Maladies d'origine alimentaire , Épidémies de maladies , Maladies d'origine alimentaire/épidémiologie , Maladies d'origine alimentaire/étiologie , Humains , Rappel mnésique , Surveillance de la population , Études rétrospectives , Facteurs de risque , États-Unis/épidémiologie
9.
J Public Health Policy ; 43(2): 185-202, 2022 Jun.
Article de Anglais | MEDLINE | ID: mdl-35614203

RÉSUMÉ

Widespread destruction from the Yemeni Civil War (2014-present) triggered the world's largest cholera outbreak. We compiled a comprehensive health dataset and created dynamic maps to demonstrate spatiotemporal changes in cholera infections and war conflicts. We aligned and merged daily, weekly, and monthly epidemiological bulletins of confirmed cholera infections and daily conflict events and fatality records to create a dataset of weekly time series for Yemen at the governorate level (subnational regions administered by governors) from 4 January 2016 through 29 December 2019. We demonstrated the use of dynamic mapping for tracing the onset and spread of infection and manmade factors that amplify the outbreak. We report curated data and visualization techniques to further uncover associations between infectious disease outbreaks and risk factors and to better coordinate humanitarian aid and relief efforts during complex emergencies.


Sujet(s)
Choléra , Choléra/épidémiologie , Épidémies de maladies , Humains , Facteurs de risque , Facteurs temps , Yémen/épidémiologie
10.
Article de Anglais | MEDLINE | ID: mdl-35270590

RÉSUMÉ

Public health agencies routinely collect time-referenced records to describe and compare foodborne outbreak characteristics. Few studies provide comprehensive metadata to inform researchers of data limitations prior to conducting statistical modeling. We described the completeness of 103 variables for 22,792 outbreaks publicly reported by the United States Centers for Disease Control and Prevention's (US CDC's) electronic Foodborne Outbreak Reporting System (eFORS) and National Outbreak Reporting System (NORS). We compared monthly trends of completeness during eFORS (1998−2008) and NORS (2009−2019) reporting periods using segmented time series analyses adjusted for seasonality. We quantified the overall, annual, and monthly completeness as the percentage of outbreaks with blank records per our study period, calendar year, and study month, respectively. We found that outbreaks of unknown genus (n = 7401), Norovirus (n = 6414), Salmonella (n = 2872), Clostridium (n = 944), and multiple genera (n = 779) accounted for 80.77% of all outbreaks. However, crude completeness ranged from 46.06% to 60.19% across the 103 variables assessed. Variables with the lowest crude completeness (ranging 3.32−6.98%) included pathogen, specimen etiological testing, and secondary transmission traceback information. Variables with low (<35%) average monthly completeness during eFORS increased by 0.33−0.40%/month after transitioning to NORS, most likely due to the expansion of surveillance capacity and coverage within the new reporting system. Examining completeness metrics in outbreak surveillance systems provides essential information on the availability of data for public reuse. These metadata offer important insights for public health statisticians and modelers to precisely monitor and track the geographic spread, event duration, and illness intensity of foodborne outbreaks.


Sujet(s)
Maladies d'origine alimentaire , Norovirus , 31808 , Épidémies de maladies , Maladies d'origine alimentaire/épidémiologie , Maladies d'origine alimentaire/étiologie , Humains , Surveillance de la population , États-Unis/épidémiologie
11.
Epidemiol Infect ; 150: e50, 2022 02 14.
Article de Anglais | MEDLINE | ID: mdl-35249590

RÉSUMÉ

Foodborne and waterborne gastrointestinal infections and their associated outbreaks are preventable, yet still result in significant morbidity, mortality and revenue loss. Many enteric infections demonstrate seasonality, or annual systematic periodic fluctuations in incidence, associated with climatic and environmental factors. Public health professionals use statistical methods and time series models to describe, compare, explain and predict seasonal patterns. However, descriptions and estimates of seasonal features, such as peak timing, depend on how researchers define seasonality for research purposes and how they apply time series methods. In this review, we outline the advantages and limitations of common methods for estimating seasonal peak timing. We provide recommendations improving reporting requirements for disease surveillance systems. Greater attention to how seasonality is defined, modelled, interpreted and reported is necessary to promote reproducible research and strengthen proactive and targeted public health policies, intervention strategies and preparedness plans to dampen the intensity and impacts of seasonal illnesses.


Sujet(s)
Épidémies de maladies , Maladies gastro-intestinales , Maladies gastro-intestinales/épidémiologie , Humains , Incidence , Saisons , Facteurs temps
12.
Adv Nutr ; 13(3): 748-757, 2022 06 01.
Article de Anglais | MEDLINE | ID: mdl-35254406

RÉSUMÉ

The rapid expansion of food and nutrition information requires new ways of data sharing and dissemination. Interactive platforms integrating data portals and visualization dashboards have been effectively utilized to describe, monitor, and track information related to food and nutrition; however, a comprehensive evaluation of emerging interactive systems is lacking. We conducted a systematic review on publicly available dashboards using a set of 48 evaluation metrics for data integrity, completeness, granularity, visualization quality, and interactivity based on 4 major principles: evidence, efficiency, emphasis, and ethics. We evaluated 13 dashboards, summarized their characteristics, strengths, and limitations, and provided guidelines for developing nutrition dashboards. We applied mixed effects models to summarize evaluation results adjusted for interrater variability. The proposed metrics and evaluation principles help to improve data standardization and harmonization, dashboard performance and usability, broaden information and knowledge sharing among researchers, practitioners, and decision makers in the field of food and nutrition, and accelerate data literacy and communication.

13.
Article de Anglais | MEDLINE | ID: mdl-35162344

RÉSUMÉ

Critical temporal changes such as weekly fluctuations in surveillance systems often reflect changes in laboratory testing capacity, access to testing or healthcare facilities, or testing preferences. Many studies have noted but few have described day-of-the-week (DoW) effects in SARS-CoV-2 surveillance over the major waves of the novel coronavirus 2019 pandemic (COVID-19). We examined DoW effects by non-pharmaceutical intervention phases adjusting for wave-specific signatures using the John Hopkins University's (JHU's) Center for Systems Science and Engineering (CSSE) COVID-19 data repository from 2 March 2020 through 7 November 2021 in Middlesex County, Massachusetts, USA. We cross-referenced JHU's data with Massachusetts Department of Public Health (MDPH) COVID-19 records to reconcile inconsistent reporting. We created a calendar of statewide non-pharmaceutical intervention phases and defined the critical periods and timepoints of outbreak signatures for reported tests, cases, and deaths using Kolmogorov-Zurbenko adaptive filters. We determined that daily death counts had no DoW effects; tests were twice as likely to be reported on weekdays than weekends with decreasing effect sizes across intervention phases. Cases were also twice as likely to be reported on Tuesdays-Fridays (RR = 1.90-2.69 [95%CI: 1.38-4.08]) in the most stringent phases and half as likely to be reported on Mondays and Tuesdays (RR = 0.51-0.93 [0.44, 0.97]) in less stringent phases compared to Sundays; indicating temporal changes in laboratory testing practices and use of healthcare facilities. Understanding the DoW effects in daily surveillance records is valuable to better anticipate fluctuations in SARS-CoV-2 testing and manage appropriate workflow. We encourage health authorities to establish standardized reporting protocols.


Sujet(s)
COVID-19 , Dépistage de la COVID-19 , Humains , Massachusetts/épidémiologie , Pandémies , SARS-CoV-2
14.
Article de Anglais | MEDLINE | ID: mdl-34516374

RÉSUMÉ

Nuclear reactor inspections are critical to ensure the safety and reliability of a nuclear facility's operation. In Canada, ultrasonic testing (UT) is used to inspect the health of pressure tubes that are part of Canada's Deuterium Uranium (CANDU) reactor's fuel channels. Currently, analysis of UT scans is performed by manual visualization and measurement to locate, characterize, and disposition flaws. Therefore, there is motivation to develop an automated method that is fast and accurate. In this article, a proof of concept (PoC) that automates the detection of flaws in nuclear fuel channel UT scans using a convolutional neural network (CNN) is presented. The CNN model was trained after constructing a dataset using historical UT scans and the corresponding inspection results. The requirement for this prototype was to identify the location of at least a portion of each flaw in UT scans while minimizing false positives (FPs). The proposed CNN model achieves this target by automatically identifying at least a portion of each flaw where further manual analysis is performed to identify the width, the length, and the type of the flaw.


Sujet(s)
Apprentissage profond , 29935 , Reproductibilité des résultats , Tomodensitométrie , Science des ultrasons
15.
Int Stat Rev ; 90(Suppl 1): S82-S95, 2022 Dec.
Article de Anglais | MEDLINE | ID: mdl-38607896

RÉSUMÉ

The confluence of growing analytic capacities and global surveillance systems for seasonal infections has created new opportunities to further develop statistical methodology and advance the understanding of the global disease dynamics. We developed a framework to characterise the seasonality of infectious diseases for publicly available global health surveillance data. Specifically, we aimed to estimate the seasonal characteristics and their uncertainty using mixed effects models with harmonic components and the δ-method and develop multi-panel visualisations to present complex interplay of seasonal peaks across geographic locations. We compiled a set of 2 422 weekly time series of 14 reported outcomes for 173 Member States from the World Health Organization's (WHO) international influenza virological surveillance system, FluNet, from 02 January 1995 through 20 June 2021. We produced an analecta of data visualisations to describe global travelling waves of influenza while addressing issues of data completeness and credibility. Our results offer directions for further improvements in data collection, reporting, analysis and development of statistical methodology and predictive approaches.

16.
J Med Internet Res ; 23(12): e26988, 2021 12 06.
Article de Anglais | MEDLINE | ID: mdl-34874885

RÉSUMÉ

BACKGROUND: Self-monitoring food intake is a cornerstone of national recommendations for health, but existing apps for this purpose are burdensome for users and researchers, which limits use. OBJECTIVE: We developed and pilot tested a new app (COCO Nutritionist) that combines speech understanding technology with technologies for mapping foods to appropriate food composition codes in national databases, for lower-burden and automated nutritional analysis of self-reported dietary intake. METHODS: COCO was compared with the multiple-pass, interviewer-administered 24-hour recall method for assessment of energy intake. COCO was used for 5 consecutive days, and 24-hour dietary recalls were obtained for two of the days. Participants were 35 women and men with a mean age of 28 (range 20-58) years and mean BMI of 24 (range 17-48) kg/m2. RESULTS: There was no significant difference in energy intake between values obtained by COCO and 24-hour recall for days when both methods were used (mean 2092, SD 1044 kcal versus mean 2030, SD 687 kcal, P=.70). There were also no significant differences between the methods for percent of energy from protein, carbohydrate, and fat (P=.27-.89), and no trend in energy intake obtained with COCO over the entire 5-day study period (P=.19). CONCLUSIONS: This first demonstration of a dietary assessment method using natural spoken language to map reported foods to food composition codes demonstrates a promising new approach to automate assessments of dietary intake.


Sujet(s)
Régime alimentaire , Langage , Adulte , Consommation alimentaire , Ration calorique , Femelle , Humains , Mâle , Adulte d'âge moyen , Autorapport , Jeune adulte
17.
Article de Anglais | MEDLINE | ID: mdl-34299881

RÉSUMÉ

Military field hospitals typically provide essential medical care in combat zones. In recent years, the United States (US) Army has deployed these facilities to assist domestic humanitarian emergency and natural disaster response efforts. As part of the nation's whole-of-government approach to the coronavirus disease (COVID-19) pandemic, directed by the Federal Emergency Management Agency and the Department of Health and Human Services, during New York City's (NYC) initial surge of COVID-19, from 26 March to 1 May 2020, the US Army erected the Javits New York Medical Station (JNYMS) field hospital to support the city's overwhelmed healthcare system. The JNYMS tasked a nutrition operations team (NuOp) to provide patient meals and clinical nutrition evaluations to convalescent COVID-19 patients. However, few guidelines were available for conducting emergency nutrition and dietary response efforts prior to the field hospital's opening. In this case study, we summarize the experiences of the NuOp at the JNYMS field hospital, to disseminate the best practices for future field hospital deployments. We then explain the challenges in service performance, due to information, personnel, supply, and equipment shortages. We conclude by describing the nutrition service protocols that have been implemented to overcome these challenges, including creating a standardized recordkeeping system for patient nutrition information, developing a meal tracking system to forecast meal requirements with food service contractors, and establishing a training and staffing model for military-to-civilian command transition. We highlight the need for a standardized humanitarian emergency nutrition service response framework and propose a Nutrition Response Toolkit for Humanitarian Crises, which offers low-cost, easily adaptable operational protocols for implementation in future field hospital deployments.


Sujet(s)
COVID-19 , Humains , État de New York , New York (ville) , Pandémies , SARS-CoV-2 , États-Unis , Effectif
18.
Sci Rep ; 11(1): 795, 2021 01 12.
Article de Anglais | MEDLINE | ID: mdl-33437025

RÉSUMÉ

For several decades, the World Health Organization has collected, maintained, and distributed invaluable country-specific disease surveillance data that allow experts to develop new analytical tools for disease tracking and forecasting. To capture the extent of available data within these sources, we proposed a completeness metric based on the effective time series length. Using FluNet records for 29 Pan-American countries from 2005 to 2019, we explored whether completeness was associated with health expenditure indicators adjusting for surveillance system heterogeneity. We observed steady improvements in completeness by 4.2-6.3% annually, especially after the A(H1N1)-2009 pandemic, when 24 countries reached > 95% completeness. Doubling in decadal health expenditure per capita was associated with ~ 7% increase in overall completeness. The proposed metric could navigate experts in assessing open access data quality and quantity for conducting credible statistical analyses, estimating disease trends, and developing outbreak forecasting systems.


Sujet(s)
Grippe humaine/épidémiologie , Orthomyxoviridae/isolement et purification , Accès à l'information , Amériques/épidémiologie , Exactitude des données , Collecte de données/économie , Collecte de données/méthodes , Épidémies de maladies , Humains , Grippe humaine/diagnostic , Grippe humaine/économie , Grippe humaine/prévention et contrôle , Organisation mondiale de la santé
19.
Article de Anglais | MEDLINE | ID: mdl-35010649

RÉSUMÉ

The Global Task Force on Cholera Control (GTFCC) created a strategy for early outbreak detection, hotspot identification, and resource mobilization coordination in response to the Yemeni cholera epidemic. This strategy requires a systematic approach for defining and classifying outbreak signatures, or the profile of an epidemic curve and its features. We used publicly available data to quantify outbreak features of the ongoing cholera epidemic in Yemen and clustered governorates using an adaptive time series methodology. We characterized outbreak signatures and identified clusters using a weekly time series of cholera rates in 20 Yemeni governorates and nationally from 4 September 2016 through 29 December 2019 as reported by the World Health Organization (WHO). We quantified critical points and periods using Kolmogorov-Zurbenko adaptive filter methodology. We assigned governorates into six clusters sharing similar outbreak signatures, according to similarities in critical points, critical periods, and the magnitude of peak rates. We identified four national outbreak waves beginning on 12 September 2016, 6 March 2017, 28 May 2018, and 28 January 2019. Among six identified clusters, we classified a core regional hotspot in Sana'a, Sana'a City, and Al-Hudaydah-the expected origin of the national outbreak. The five additional clusters differed in Wave 2 and Wave 3 peak frequency, timing, magnitude, and geographic location. As of 29 December 2019, no governorates had returned to pre-Wave 1 levels. The detected similarity in outbreak signatures suggests potentially shared environmental and human-made drivers of infection; the heterogeneity in outbreak signatures implies the potential traveling waves outwards from the core regional hotspot that could be governed by factors that deserve further investigation.


Sujet(s)
Choléra , Épidémies , Choléra/épidémiologie , Villes , Épidémies de maladies , Humains , Organisation mondiale de la santé
20.
Sci Data ; 7(1): 346, 2020 10 13.
Article de Anglais | MEDLINE | ID: mdl-33051470

RÉSUMÉ

Disease surveillance systems worldwide face increasing pressure to maintain and distribute data in usable formats supplemented with effective visualizations to enable actionable policy and programming responses. Annual reports and interactive portals provide access to surveillance data and visualizations depicting temporal trends and seasonal patterns of diseases. Analyses and visuals are typically limited to reporting the annual time series and the month with the highest number of cases per year. Yet, detecting potential disease outbreaks and supporting public health interventions requires detailed spatiotemporal comparisons to characterize spatiotemporal patterns of illness across diseases and locations. The Centers for Disease Control and Prevention's (CDC) FoodNet Fast provides population-based foodborne-disease surveillance records and visualizations for select counties across the US. We offer suggestions on how current FoodNet Fast data organization and visual analytics can be improved to facilitate data interpretation, decision-making, and communication of features related to trend and seasonality. The resulting compilation, or analecta, of 436 visualizations of records and codes are openly available online.


Sujet(s)
Épidémies de maladies , Maladies d'origine alimentaire/épidémiologie , Saisons , Jeux de données comme sujet , Humains , Surveillance de la population , États-Unis/épidémiologie
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