RÉSUMÉ
BACKGROUND: Brooke-Spiegler syndrome is a well known but rare cutaneous disorder characterized by the presence of multiple trichoepitheliomas and cylindromas. METHODS: Four families with Brooke-Spiegler syndrome are described. RESULTS: Spiradenomas developed on the back in two patients. A CO(2) laser was used to treat facial trichoepitheliomas in two patients with good results. CONCLUSIONS: The large number of facial lesions in this syndrome often produce a significant emotional impact. We believe that it is important to provide patients with a good therapeutic option. CO(2) laser therapy may fill this role.
Sujet(s)
Adénome des glandes sudoripares/chirurgie , Carcinome adénoïde kystique/chirurgie , Thérapie laser , Tumeurs des annexes cutanées/chirurgie , Tumeurs primitives multiples/chirurgie , Syndromes néoplasiques héréditaires/chirurgie , Tumeurs cutanées/chirurgie , Adénome des glandes sudoripares/anatomopathologie , Adulte , Sujet âgé , Carcinome adénoïde kystique/anatomopathologie , Enfant , Face/anatomopathologie , Femelle , Humains , Mâle , Adulte d'âge moyen , Tumeurs des annexes cutanées/anatomopathologie , Tumeurs primitives multiples/anatomopathologie , Syndromes néoplasiques héréditaires/anatomopathologie , Cuir chevelu/anatomopathologie , Tumeurs cutanées/anatomopathologieRÉSUMÉ
BACKGROUND: Pancreatic panniculitis is a rare complication of pancreatic disease. Histopathologic findings are pathognomonic and may be helpful for early diagnosis. METHODS: We present a female kidney transplant recipient, with systemic lupus erythematosus on immunossuppresive therapy, who developed panniculitis. RESULTS: Histological features strongly suggested pancreatic panniculitis and this was confirmed by clinical, laboratory and image findings. CONCLUSION: The characteristic histologic features of pancreatic panniculitis may help to uncover undiagnosed pancreatic disease. Early therapy may avoid ensuing serious complications.
Sujet(s)
Transplantation rénale/effets indésirables , Maladies du pancréas/étiologie , Panniculite/étiologie , Adulte , Femelle , Humains , Maladies du pancréas/anatomopathologie , Panniculite/anatomopathologieRÉSUMÉ
Our study took place in the region of the Copahue Volcano in the Andes Mountain range, 1900 m above sea level. Fifty-five patients who came to the Copahue Thermal Basin Complex (Neuquén, Argentina) for treatment of psoriasis vulgaris were clinically evaluated for participation in this study. Thermal products--waters, mud, and/or algae--were the only therapeutic agents used, except for bland emollients for xerosis. Treatment for brief periods (10 +/- 3 days) resulted in notable improvement.
Sujet(s)
Balnéologie , Psoriasis/thérapie , Argentine , Femelle , Humains , MâleRÉSUMÉ
BACKGROUND AND OBJECTIVES: Burning mouth syndrome (BMS) is a frequent process that produces marked oral dysesthetic symptoms. There is controversy over its etiopathogenesis and diagnosis. Therapeutic results are unsatisfactory. The objectives of this study were: (1) to analyze a possible agreement on the definition of BMS; (2) to analyze its cause; (3) to propose a therapeutic scheme that has been shown to be highly effective in our experience and has not been previously reported. METHODS: Five hundred patients with symptomatology of BMS were retrospectively evaluated with a study protocol, specially designed for this disease. Patients with local or general disease processes that could cause secondary asymptomatic stomatodynia were excluded from the study. RESULTS: Most of the patients evaluated were women over 60 years of age with oral symptoms, including a sensation of heat and burning, and pain, lasting for months or years, and a history of multiple unsuccessful treatments. The patients showed depression associated with anxiety, with evidence of psychiatric disorders in the family. Based on these findings and eliminating symptomatic painful conditions of the mouth that may stimulate this syndrome, we diagnosed a genuine or basic BMS of psychosomatic origin. Therapies used in the treatment of these neurotic conditions were not always useful. Tranylcypromine associated with anxiolytics and hypnotics in low doses plus the support of psychotherapy by the stomatologist were the most effective treatments. CONCLUSIONS: The BMS should be defined as a psychosomatic process causing oral dysesthesias for months or years.
Sujet(s)
Stomatodynie , Adulte , Répartition par âge , Sujet âgé , Sujet âgé de 80 ans ou plus , Anxiolytiques/usage thérapeutique , Antidépresseurs/usage thérapeutique , Antidépresseurs tricycliques/usage thérapeutique , Stomatodynie/épidémiologie , Stomatodynie/étiologie , Stomatodynie/physiopathologie , Stomatodynie/thérapie , Femelle , Humains , Mâle , Adulte d'âge moyen , Pronostic , Études rétrospectives , Répartition par sexe , Facteurs socioéconomiquesSujet(s)
Candidose cutanée/traitement médicamenteux , Fluconazole/usage thérapeutique , Kétoconazole/usage thérapeutique , Pied d'athlète/traitement médicamenteux , Teigne/traitement médicamenteux , Adulte , Candida/isolement et purification , Candidose cutanée/microbiologie , Méthode en double aveugle , Femelle , Fluconazole/administration et posologie , Fluconazole/effets indésirables , Études de suivi , Humains , Kétoconazole/administration et posologie , Kétoconazole/effets indésirables , Mâle , Placebo , Récidive , Induction de rémission , Surinfection/diagnostic , Teigne/microbiologie , Pied d'athlète/microbiologie , Trichophyton/isolement et purificationSujet(s)
Ecthyma/microbiologie , Infections à Pseudomonas/anatomopathologie , Pseudomonas aeruginosa , Dermatoses bactériennes/anatomopathologie , Adulte , Enfant d'âge préscolaire , Diabète de type 1 , Dermatoses faciales/microbiologie , Femelle , Gangrène , Humains , Mâle , Cou/anatomopathologie , Maladies du nez/microbiologie , Leucémie-lymphome lymphoblastique à précurseurs B et TRÉSUMÉ
Two patients who developed porphyria cutanea tarda, six and eight years after a successful renal transplantation are reported. There was no history, in either of them, of alcohol abuse, blood transfusion, iron or estrogen therapy and any hemodialysis in the last years. There is no evidence to support that a renal allograft is capable to develop porphyria cutanea tarda. Nevertheless, it would be interesting to consider its possible influence, due to the longer survival of these patients.
Sujet(s)
Humains , Mâle , Adulte , Transplantation rénale , Porphyrie cutanée tardive/étiologie , Dialyse rénale/effets indésirables , Hydroxychloroquine , Porphyrie cutanée tardive/diagnostic , Porphyrie cutanée tardive/traitement médicamenteux , Facteurs tempsRÉSUMÉ
Two patients who developed porphyria cutanea tarda, six and eight years after a successful renal transplantation are reported. There was no history, in either of them, of alcohol abuse, blood transfusion, iron or estrogen therapy and any hemodialysis in the last years. There is no evidence to support that a renal allograft is capable to develop porphyria cutanea tarda. Nevertheless, it would be interesting to consider its possible influence, due to the longer survival of these patients.(Au)
Sujet(s)
Humains , Mâle , Adulte , Transplantation rénale , Porphyrie cutanée tardive/étiologie , Hydroxychloroquine/usage thérapeutique , Porphyrie cutanée tardive/diagnostic , Porphyrie cutanée tardive/traitement médicamenteux , Dialyse rénale/effets indésirables , Facteurs tempsRÉSUMÉ
Two patients who developed porphyria cutanea tarda, six and eight years after a successful renal transplantation are reported. There was no history, in either of them, of alcohol abuse, blood transfusion, iron or estrogen therapy and any hemodialysis in the last years. There is no evidence to support that a renal allograft is capable to develop porphyria cutanea tarda. Nevertheless, it would be interesting to consider its possible influence, due to the longer survival of these patients.
Sujet(s)
Transplantation rénale , Porphyrie cutanée tardive/étiologie , Adulte , Humains , Hydroxychloroquine/usage thérapeutique , Mâle , Porphyrie cutanée tardive/diagnostic , Porphyrie cutanée tardive/traitement médicamenteux , Dialyse rénale/effets indésirables , Facteurs tempsRÉSUMÉ
Two patients who developed porphyria cutanea tarda, six and eight years after a successful renal transplantation are reported. There was no history, in either of them, of alcohol abuse, blood transfusion, iron or estrogen therapy and any hemodialysis in the last years. There is no evidence to support that a renal allograft is capable to develop porphyria cutanea tarda. Nevertheless, it would be interesting to consider its possible influence, due to the longer survival of these patients.
RÉSUMÉ
Se presentan dos casos de PANC de 15 y 68 años respectivamente pertenecientes al sexo masculino. El caso 1 presenta nódulos, livedo reticular y racemoso con adelgazamiento, astenia y anemia sin compromiso visceral ostensible. Evoluciona con involución de lesiones cutáneas y síntomas generales luego de un breve período de administración de corticoesteroides por via general. Se halla assintomático en la actualidad sin corticoterapia. El caso 2 presenta livedo racemoso y reticular con áreas atróficas y nódulos ocasionales. Se trata con antiinflamatorios no esteroides y no tiene evolución posterior conocida. Se resumen las características que permiten diferenciar formas predominantemente cutáneas de las sistémicas cuyo tratamiento y pronóstico difieren, sosteniendo la idea de un espectro continuo semejante a lo del lupus eritematoso
Sujet(s)
Adolescent , Sujet âgé , Humains , Mâle , Polyartérite noueuse/diagnostic , Peau , Acide acétylsalicylique/usage thérapeutique , Cyclophosphamide/usage thérapeutique , Diagnostic différentiel , Piroxicam/usage thérapeutique , Polyartérite noueuse/traitement médicamenteux , PronosticRÉSUMÉ
Se presentan dos casos de PANC de 15 y 68 años respectivamente pertenecientes al sexo masculino. El caso 1 presenta nódulos, livedo reticular y racemoso con adelgazamiento, astenia y anemia sin compromiso visceral ostensible. Evoluciona con involución de lesiones cutáneas y síntomas generales luego de un breve período de administración de corticoesteroides por via general. Se halla assintomático en la actualidad sin corticoterapia. El caso 2 presenta livedo racemoso y reticular con áreas atróficas y nódulos ocasionales. Se trata con antiinflamatorios no esteroides y no tiene evolución posterior conocida. Se resumen las características que permiten diferenciar formas predominantemente cutáneas de las sistémicas cuyo tratamiento y pronóstico difieren, sosteniendo la idea de un espectro continuo semejante a lo del lupus eritematoso (AU)