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PLoS Negl Trop Dis ; 13(5): e0007399, 2019 05.
Article de Anglais | MEDLINE | ID: mdl-31095570

RÉSUMÉ

BACKGROUND: Imported strongyloidiasis is increasingly being diagnosed in non-endemic areas. The aim of this study was to describe the epidemiological, clinical and microbiological characteristics of patients with imported strongyloidiasis in Spain. METHODOLOGY: This is an observational retrospective study that included all patients diagnosed of strongyloidiasis registered in the +REDIVI Collaborative Network from 2009 to 2017. Demographic, epidemiological and clinical information was collected from the +REDIVI database, and extra information regarding microbiological techniques, treatment and follow-up was requested to participant centers. FINDINGS: Overall, 1245 cases were included. Most of them were immigrants (66.9%), and South America was the most frequent area of origin. Detection of larvae in stool samples was observed in 21.9% of the patients, and serological tests allowed making the diagnosis in the rest of the cases. Eosinophilia was present in 82.2% of cases. Treatment with ivermectin (compared with albendazole) was the most strongly associated factor to achieve the cure (OR 2.34). CONCLUSIONS: Given the long latency of the infection and the risk of developing a severe presentation, screening of S. stercoralis infection should be mandatory in patients coming from or had traveling to endemic areas, especially in those with immunosuppressant conditions.


Sujet(s)
Anthelminthiques/usage thérapeutique , Strongyloïdose/épidémiologie , Adolescent , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Albendazole/usage thérapeutique , Animaux , Enfant , Enfant d'âge préscolaire , Émigrants et immigrants/statistiques et données numériques , Éosinophilie/étiologie , Femelle , Humains , Nourrisson , Ivermectine/usage thérapeutique , Mâle , Adulte d'âge moyen , Études rétrospectives , Amérique du Sud , Espagne/épidémiologie , Strongyloides stercoralis/effets des médicaments et des substances chimiques , Strongyloides stercoralis/isolement et purification , Strongyloides stercoralis/physiologie , Strongyloïdose/complications , Strongyloïdose/diagnostic , Strongyloïdose/parasitologie , Voyage , Jeune adulte
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