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Gynecol Obstet Fertil ; 38(3): 183-92, 2010 Mar.
Article de Français | MEDLINE | ID: mdl-20153682

RÉSUMÉ

High risk may be defined as either an absolute risk greater than 20 % or a relative risk greater than 4. Concerning breast and ovarian cancer, high risk patients include carriers of a constitutive deleterious mutation of BRCA1 or BRCA2 genes, patients with a significant family history of breast or ovarian cancer, and patients who have been diagnosed a benign breast lesion with a high risk of degeneration, i.e. atypical hyperplasia. Following up such patients relies on specific strategies. A center including a large panel of physicians involved in the various modalities for patients' management (geneticians, radiologists, gynecologists, plastic surgeons, pathologists, endocrinologists, psychologists, medical oncologists) has been created at Tenon Hospital with this purpose. The collaboration of these different specialists with the referent physician of the patient allows for the definition and the implementation of a patient-centered follow-up continuously updated to take into account the different periods of a woman's life, according to best practices recommendations and the evolving state-of-the art.


Sujet(s)
Tumeurs du sein/prévention et contrôle , Unités hospitalières/organisation et administration , Tumeurs de l'ovaire/prévention et contrôle , Spécialisation , Région mammaire/anatomopathologie , Maladies du sein/anatomopathologie , Tumeurs du sein/génétique , Tumeurs du sein/anatomopathologie , Femelle , France , Gène BRCA1 , Gène BRCA2 , Prédisposition génétique à une maladie , Humains , Hyperplasie , Mutation , Tumeurs de l'ovaire/génétique , Médecins , Orientation vers un spécialiste , Facteurs de risque
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