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J Pediatric Infect Dis Soc ; 12(3): 169-172, 2023 Apr 18.
Article de Anglais | MEDLINE | ID: mdl-36537278

RÉSUMÉ

We performed an observational cohort study to assess associations between genetic factors of dengue fever (DF) severity in children in the Dominican Republic. A total of 488 participants had serologically confirmed DF. We replicated the association between the IFIH1 gene (rs1990760) and severe DF (n = 80/488, p = 0.006) and identified novel associations needing further investigation.


Sujet(s)
Dengue , Dengue sévère , Humains , Enfant , Dengue/diagnostic , Dengue/épidémiologie , République dominicaine/épidémiologie , Études de cohortes , Génomique
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