Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic.

Microorganisms cause variety of diseases that constitutes a severe threat to mankind. Due to the upsurge of many infectious diseases, there is a high requirement and demand for the development of safety products finished with antimicrobial properties. The study involves the antimicrobial activity of natural cotton coated with copper iodide capped with Hibiscus rosa-sinensis L. flower extract (CuI-FE) which is rich in anthocyanin, cyanidin-3-sophoroside by ultrasonication method. The coated and uncoated cotton fabric was characterised through XRD, SEM, AFM, tensile strength and UV-Visible spectroscopic techniques. XRD confirmed the formation of CuI particles, SEM showed that CuI-FE was prismatic in shape. The average size of CuI-FE particles was found to be 552.45 nm. Anti-bacterial studies showed copper iodide particles to be a potent antimicrobial agent. AFM images confirmed the rupture of bacterial cell walls in the presence of prismatic CuI-FE. In-vitro cytotoxicity investigation of CuI-FE was performed against cancer and spleen cell lines to evaluate the cell viability. Cytotoxicity analysis revealed the IC50 value of 233.93 µg/mL in the presence of CuI-FE. Molecular docking study was also carried out to understand the interaction of CuI-FE with COVID-19 main protease. This paper has given an insight on the usage of CuI-FE coated on the cotton fabric that has proved to have strong inhibition against the nano ranged bacterial, cancerous cell line and a strong interaction with the COVID-19 protease. Such eco-friendly material will provide a safe environment even after the disposable of medical waste from the infectious diseases like influenza and current pandemic like COVID-19.

Caracterização antibacteriana e fitoquímica de flores de Hibiscus rosa-sinensis L. (mimo-de-vênus) e Hibiscus syriacus L. (hibisco-da-síria) / Antibacterial and phytochemical characterization of flowers of Hibiscus rosa-sinensis L. (treat-of-venus) and Hibiscus syriacus L. (hibiscus-the-syrian)

Hibiscus rosa-sinensis e o Hibiscus syriacus são considerados flores comestíveis e estudos demonstram seu potencial antibacteriano frente a diversos micro-organismos. Este trabalho teve por objetivo analisara Intensidade de Atividade de Inibição (IINIB) e a Inativação Bacteriana (IINAB) in vitro dos extratos alcoólicos das flores dos hibiscos e a relação com os polifenóis e antocianinas revelados. Avaliou-se a ação antibacteriana frente às bactérias de interesse alimentar, Staphylococcus aureus e Salmonella Enteritidis resultando em diferenças significativas entre as médias de IINIB/IINAB, sendo S. aureus a cepa maisresistente para o H. syriacus e S. Enteritidis a mais sensível em ambos os experimentos. Com relação ao H. rosa-sinensis, este foi eficaz para ambas as bactérias. O teor dos compostos fitoquímicos presentes nas plantas constatou que há uma forte correlação positiva com a atividade antibacteriana (r = 0,88),sendo que o H. rosa-sinensis obteve poder antibacteriano maior do que o H. syriacus, presumindo estar relacionado à maior quantidade de polifenóis e antocianinas detectadas no primeiro. Conclui-se que as plantas estudadas têm poder bactericida e bacteriostático podendo agir contra a contaminação bacteriana...

Antibacterial and phytochemical characterization of flowers of Hibiscus rosa-sinensis L. (treat-of-venus) and Hibiscus syriacus L. (hibiscus-the-syrian) / Caracterização antibacteriana e fitoquímica de flores de Hibiscus rosa-sinensis L. (mimo-de-vênus) e Hibiscus syriacus L. (hibisco-da-síria)

Hibiscus rosa-sinensis Hibiscus syriacus and edible flowers are considered and studies demonstrate the potential antibacterial against various microorganisms. This study aimed to analyze the Inhibition of Activity Intensity (IINIB) and the Bacterial Inactivation (IINAB) in vitro of alcoholic extracts of flowers of hibiscus and the relationship with the revealed polyphenols and anthocyanins. We evaluated the front antibacterial action of food interest bacteria, Staphylococcus aureus and Salmonella Enteritidis resulting in significant differences between the mean IINIB/IINAB, S. aureus being the most resistant microorganism strain to H. syriacus and S. Enteritidis was the most sensitive bacteria in both experiments. Concerning the H. rosa-sinensis was effective for both bacteria. The content of phytochemicals compounds found in plants there is a strong positive correlation with the antibacterial activity (r = 0.88), and H. rosa-sinensis obtained antibacterial power greater than H. syriacus, assuming be related to increased amount of polyphenols and anthocyanins detected at first. We conclude that the plants have bactericidal and bacteriostatic studied power may act against bacterial contamination.(AU)

Hibiscus rosa-sinensis e o Hibiscus syriacus são considerados flores comestíveis e estudos demonstram seu potencial antibacteriano frente a diversos micro-organismos. Este trabalho teve por objetivo analisar a Intensidade de Atividade de Inibição (IINIB) e a Inativação Bacteriana (IINAB) in vitro dos extratos alcoólicos das flores dos hibiscos e a relação com os polifenóis e antocianinas revelados. Avaliou-se a ação antibacteriana frente às bactérias de interesse alimentar, Staphylococcus aureus e Salmonella Enteritidis resultando em diferenças significativas entre as médias de IINIB/IINAB, sendo S. aureus a cepa mais resistente para o H. syriacus e S. Enteritidis a mais sensível em ambos os experimentos. Com relação ao H. rosa-sinensis, este foi eficaz para ambas as bactérias. O teor dos compostos fitoquímicos presentes nas plantas constatou que há uma forte correlação positiva com a atividade antibacteriana (r = 0,88), sendo que o H. rosa-sinensis obteve poder antibacteriano maior do que o H. syriacus, presumindo estar relacionado à maior quantidade de polifenóis e antocianinas detectadas no primeiro. Conclui-se que as plantas estudadas têm poder bactericida e bacteriostático podendo agir contra a contaminação bacteriana.(AU)