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1.
J Imaging ; 10(9)2024 Sep 04.
Article de Anglais | MEDLINE | ID: mdl-39330438

RÉSUMÉ

Breast cancer is the most commonly diagnosed cancer worldwide. The therapy used and its success depend highly on the histology of the tumor. This study aimed to explore the potential of predicting the molecular subtype of breast cancer using radiomic features extracted from screening digital mammography (DM) images. A retrospective study was performed using the OPTIMAM Mammography Image Database (OMI-DB). Four binary classification tasks were performed: luminal A vs. non-luminal A, luminal B vs. non-luminal B, TNBC vs. non-TNBC, and HER2 vs. non-HER2. Feature selection was carried out by Pearson correlation and LASSO. The support vector machine (SVM) and naive Bayes (NB) ML classifiers were used, and their performance was evaluated with the accuracy and the area under the receiver operating characteristic curve (AUC). A total of 186 patients were included in the study: 58 luminal A, 35 luminal B, 52 TNBC, and 41 HER2. The SVM classifier resulted in AUCs during testing of 0.855 for luminal A, 0.812 for luminal B, 0.789 for TNBC, and 0.755 for HER2, respectively. The NB classifier showed AUCs during testing of 0.714 for luminal A, 0.746 for luminal B, 0.593 for TNBC, and 0.714 for HER2. The SVM classifier outperformed NB with statistical significance for luminal A (p = 0.0268) and TNBC (p = 0.0073). Our study showed the potential of radiomics for non-invasive breast cancer subtype classification.

2.
MethodsX ; 13: 102866, 2024 Dec.
Article de Anglais | MEDLINE | ID: mdl-39157818

RÉSUMÉ

Color-blind is a generic disability whereby the affected individuals are not given the opportunity to benefit from the various functions provided by color that would impact humans physically and psychologically. Although this disability is not fatal, it brought plenty of turbulence in the affected individuals' daily activities. This paper aims to develop a system for recognizing and detecting colors of clothes in images, improve accuracy by using advanced algorithms to handle lighting variations, and provide color matching recommendations to assist color-blind individuals in making informed choices when purchasing shirts. The proposed methodology for color recognition involves:•retrieving the RGB values of a given point from the input image and converting them into HSV values.•creating web application integrated with a machine learning model to classify and predict the corresponding color based on the HSV values.•predicting the color name with suggestions of matching colors will be displayed on the interface.

3.
Healthc Technol Lett ; 11(4): 213-217, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-39100505

RÉSUMÉ

Heart attack is a life-threatening condition which is mostly caused due to coronary disease resulting in death in human beings. Detecting the risk of heart diseases is one of the most important problems in medical science that can be prevented and treated with early detection and appropriate medical management; it can also help to predict a large number of medical needs and reduce expenses for treatment. Predicting the occurrence of heart diseases by machine learning (ML) algorithms has become significant work in healthcare industry. This study aims to create a such system that is used for predicting whether a patient is likely to develop heart attacks, by analysing various data sources including electronic health records and clinical diagnosis reports from hospital clinics. ML is used as a process in which computers learn from data in order to make predictions about new datasets. The algorithms created for predictive data analysis are often used for commercial purposes. This paper presents an overview to forecast the likelihood of a heart attack for which many ML methodologies and techniques are applied. In order to improve medical diagnosis, the paper compares various algorithms such as Random Forest, Regression models, K-nearest neighbour imputation (KNN), Naïve Bayes algorithm etc. It is found that the Random Forest algorithm provides a better accuracy of 88.52% in forecasting heart attack risk, which could herald a revolution in the diagnosis and treatment of cardiovascular illnesses.

4.
Sensors (Basel) ; 24(15)2024 Jul 24.
Article de Anglais | MEDLINE | ID: mdl-39123855

RÉSUMÉ

The detection performance of radar is significantly impaired by active jamming and mutual interference from other radars. This paper proposes a radio signal modulation recognition method to accurately recognize these signals, which helps in the jamming cancellation decisions. Based on the ensemble learning stacking algorithm improved by meta-feature enhancement, the proposed method adopts random forests, K-nearest neighbors, and Gaussian naive Bayes as the base-learners, with logistic regression serving as the meta-learner. It takes the multi-domain features of signals as input, which include time-domain features including fuzzy entropy, slope entropy, and Hjorth parameters; frequency-domain features, including spectral entropy; and fractal-domain features, including fractal dimension. The simulation experiment, including seven common signal types of radar and active jamming, was performed for the effectiveness validation and performance evaluation. Results proved the proposed method's performance superiority to other classification methods, as well as its ability to meet the requirements of low signal-to-noise ratio and few-shot learning.

5.
J Imaging ; 10(8)2024 Aug 19.
Article de Anglais | MEDLINE | ID: mdl-39194990

RÉSUMÉ

Breast cancer is one of the paramount causes of new cancer cases worldwide annually. It is a malignant neoplasm that develops in the breast cells. The early screening of this disease is essential to prevent its metastasis. A mammogram X-ray image is the most common screening tool practiced currently when this disease is suspected; all the breast lesions identified are not malignant. The invasive fine needle aspiration (FNA) of a breast mass sample is the secondary screening tool to clinically examine cancerous lesions. The visual image analysis of the stained aspirated sample imposes a challenge for the cytologist to identify the malignant cells accurately. The formulation of an artificial intelligence-based objective technique on top of the introspective assessment is essential to avoid misdiagnosis. This paper addresses several artificial intelligence (AI)-based techniques to diagnose breast cancer from the nuclear features of FNA samples. The Wisconsin Breast Cancer dataset (WBCD) from the UCI machine learning repository is applied for this investigation. Significant statistical parameters are measured to evaluate the performance of the proposed techniques. The best detection accuracy of 98.10% is achieved with a two-layer feed-forward neural network (FFNN). Finally, the developed algorithm's performance is compared with some state-of-the-art works in the literature.

6.
SLAS Technol ; 29(4): 100164, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-39033878

RÉSUMÉ

In the face of an aging population, smart healthcare services are now within reach, thanks to the proliferation of high-speed internet and other forms of digital technology. Data problems in smart healthcare, unfortunately, put artificial intelligence in this area to serious limitations. There are several issues, including a lack of standard samples, noisy data interference, and actual data that is missing. A three-stage AI-based data generating strategy is suggested to handle missing datasets, using a small sample dataset obtained from a smart healthcare program community in a specific city: Step one involves generating the dataset's basic attributes using a tree-based generation strategy that takes the original data distribution into account. Step two involves using the Naive Bayes algorithm to create basic indicators of behavioural capability assessment for the samples. Step three builds on stage two and uses a multivariate linear regression method to create evaluation criteria and indicators of high-level behavioural capability. Six problems involving multiple classifications and two tasks using multiple labels are implemented using various neural network-based training strategies on the obtained data to assess the usefulness of the dataset for downstream tasks. To ensure that the data collected is genuine and useful, the experimental data must be analysed and expert knowledge must be included.


Sujet(s)
Intelligence artificielle , Humains , Prestations des soins de santé , Probabilité
7.
Diabetes Obes Metab ; 26(8): 3439-3447, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-38828802

RÉSUMÉ

AIM: To explore biomarkers that can predict the response of type 2 diabetes (T2D) patients to metformin at an early stage to provide better treatment for T2D. METHODS: T2D patients with (responders) or without response (non-responders) to metformin were recruited, and their serum samples were used for metabolomic analysis to identify candidate biomarkers. Moreover, the efficacy of metformin was verified by insulin-resistant mice, and the candidate biomarkers were verified to determine the biomarkers. Five different machine learning methods were used to construct the integrated biomarker profiling (IBP) with the biomarkers to predict the response of T2D patients to metformin. RESULTS: A total of 73 responders and 63 non-responders were recruited, and 88 differential metabolites were identified in the serum samples. After being verified in mice, 19 of the 88 were considered as candidate biomarkers. Next, after metformin regulation, nine candidate biomarkers were confirmed as the biomarkers. After comparing five machine learning models, the nine biomarkers were constructed into the IBP for predicting the response of T2D patients to metformin based on the Naïve Bayes classifier, which was verified with an accuracy of 89.70%. CONCLUSIONS: The IBP composed of nine biomarkers can be used to predict the response of T2D patients to metformin, enabling clinicians to start a combined medication strategy as soon as possible if T2D patients do not respond to metformin.


Sujet(s)
Marqueurs biologiques , Diabète de type 2 , Hypoglycémiants , Apprentissage machine , Metformine , Metformine/usage thérapeutique , Metformine/pharmacologie , Diabète de type 2/traitement médicamenteux , Diabète de type 2/sang , Humains , Animaux , Hypoglycémiants/usage thérapeutique , Marqueurs biologiques/sang , Souris , Mâle , Femelle , Adulte d'âge moyen , Métabolomique/méthodes , Résultat thérapeutique , Souris de lignée C57BL , Insulinorésistance , Sujet âgé
8.
Diagnostics (Basel) ; 14(9)2024 May 01.
Article de Anglais | MEDLINE | ID: mdl-38732368

RÉSUMÉ

BACKGROUND: At the time of cancer diagnosis, it is crucial to accurately classify malignant gastric tumors and the possibility that patients will survive. OBJECTIVE: This study aims to investigate the feasibility of identifying and applying a new feature extraction technique to predict the survival of gastric cancer patients. METHODS: A retrospective dataset including the computed tomography (CT) images of 135 patients was assembled. Among them, 68 patients survived longer than three years. Several sets of radiomics features were extracted and were incorporated into a machine learning model, and their classification performance was characterized. To improve the classification performance, we further extracted another 27 texture and roughness parameters with 2484 superficial and spatial features to propose a new feature pool. This new feature set was added into the machine learning model and its performance was analyzed. To determine the best model for our experiment, Random Forest (RF) classifier, Support Vector Machine (SVM), K-Nearest Neighbors (KNN), and Naïve Bayes (NB) (four of the most popular machine learning models) were utilized. The models were trained and tested using the five-fold cross-validation method. RESULTS: Using the area under ROC curve (AUC) as an evaluation index, the model that was generated using the new feature pool yields AUC = 0.98 ± 0.01, which was significantly higher than the models created using the traditional radiomics feature set (p < 0.04). RF classifier performed better than the other machine learning models. CONCLUSIONS: This study demonstrated that although radiomics features produced good classification performance, creating new feature sets significantly improved the model performance.

9.
Epilepsy Behav ; 155: 109793, 2024 Jun.
Article de Anglais | MEDLINE | ID: mdl-38669972

RÉSUMÉ

PURPOSE: Epilepsy type, whether focal or generalised, is important in deciding anti-seizure medication (ASM). In resource-limited settings, investigations are usually not available, so a clinical separation is required. We used a naïve Bayes approach to devise an algorithm to do this, and compared its accuracy with algorithms devised by five other machine learning methods. METHODS: We used data on 28 clinical variables from 503 patients attending an epilepsy clinic in India with defined epilepsy type, as determined by an epileptologist with access to clinical, imaging, and EEG data. We adopted a machine learning approach to select the most relevant variables based on mutual information, to train the model on part of the data, and then to evaluate it on the remaining data (testing set). We used a naïve Bayes approach and compared the results in the testing set with those obtained by several other machine learning algorithms by measuring sensitivity, specificity, accuracy, area under the curve, and Cohen's kappa. RESULTS: The six machine learning methods produced broadly similar results. The best naïve Bayes algorithm contained eleven variables, and its accuracy was 92.2% in determining epilepsy type (sensitivity 92.0%, specificity 92.7%). An algorithm incorporating the best eight of these variables was only slightly less accurate - 91.0% (sensitivity 89.6%, and specificity 95.1%) - and easier for clinicians to use. CONCLUSION: A clinical algorithm with eight variables is effective and accurate at separating focal from generalised epilepsy. It should be useful in resource-limited settings, by epilepsy-inexperienced doctors, to help determine epilepsy type and therefore optimal ASMs for individual patients, without the need for EEG or neuroimaging.


Sujet(s)
Algorithmes , Théorème de Bayes , Électroencéphalographie , Épilepsies partielles , Épilepsie généralisée , Apprentissage machine , Humains , Mâle , Femelle , Adulte , Épilepsie généralisée/diagnostic , Électroencéphalographie/méthodes , Épilepsies partielles/diagnostic , Épilepsies partielles/physiopathologie , Adulte d'âge moyen , Jeune adulte , Adolescent , Sensibilité et spécificité , Enfant , Sujet âgé , Inde
10.
Clin Cardiol ; 47(4): e24264, 2024 Apr.
Article de Anglais | MEDLINE | ID: mdl-38563389

RÉSUMÉ

BACKGROUND: Recently, patients with type 2 diabetes mellitus (T2DM) have experienced a higher incidence and severer degree of vascular calcification (VC), which leads to an increase in the incidence and mortality of vascular complications in patients with T2DM. HYPOTHESIS: To construct and validate prediction models for the risk of VC in patients with T2DM. METHODS: Twenty-three baseline demographic and clinical characteristics were extracted from the electronic medical record system. Ten clinical features were screened with least absolute shrinkage and selection operator method and were used to develop prediction models based on eight machine learning (ML) algorithms (k-nearest neighbor [k-NN], light gradient boosting machine, logistic regression [LR], multilayer perception [(MLP], Naive Bayes [NB], random forest [RF], support vector machine [SVM], XGBoost [XGB]). Model performance was evaluated using the area under the receiver operating characteristic curve (AUC), accuracy, and precision. RESULTS: A total of 1407 and 352 patients were retrospectively collected in the training and test sets, respectively. Among the eight models, the AUC value in the NB model was higher than the other models (NB: 0.753, LGB: 0.719, LR: 0.749, MLP: 0.715, RF: 0.722, SVM: 0.689, XGB:0.707, p < .05 for all). The k-NN model achieved the highest sensitivity of 0.75 (95% confidence interval [CI]: 0.633-0.857), the MLP model achieved the highest accuracy of 0.81 (95% CI: 0.767-0.852) and specificity of 0.875 (95% CI: 0.836-0.912). CONCLUSIONS: This study developed a predictive model of VC based on ML and clinical features in type 2 diabetic patients. The NB model is a tool with potential to facilitate clinicians in identifying VC in high-risk patients.


Sujet(s)
Diabète de type 2 , Calcification vasculaire , Humains , Diabète de type 2/complications , Diabète de type 2/diagnostic , Diabète de type 2/épidémiologie , Études rétrospectives , Théorème de Bayes , Calcification vasculaire/diagnostic , Calcification vasculaire/épidémiologie , Calcification vasculaire/étiologie , Apprentissage machine
11.
Article de Anglais | MEDLINE | ID: mdl-38411725

RÉSUMÉ

PURPOSE: In China, individuals with substance use disorders (SUD) face severe stigma, but reliable stigma assessment tool is lacking. Therefore, this study aimed to validate the Chinese version of the Substance Use Stigma Mechanism Scale (SU-SMS-C) and set its cut-off point. METHODS: We recruited 1005 individuals with SUDs from Chinese rehabilitation centers. These participants completed a battery of questionnaires that included the SU-SMS-C, The Multidimensional Scale of Perceived Social Support (MSPSS), Center for Epidemiologic Studies Depression Scale (CES-D), General Self-Efficacy Scale (GSES), and Perceived Devaluation and Discrimination (PDD). Confirmatory factor analysis was used to assess the construct validity of the scale. Additionally, the Naive Bayes classifier was used to establish the cut-off point for the SU-SMS-C. We additionally explored the correlation between patient demographic characteristics and stigma. RESULTS: A confirmatory factor analysis was utilized, revealing a second-order five-factor model. Based on the Naive Bayes classifier, the area under the receiver operating characteristic (AUCROC) of 0.746, the cut-off point for the SU-SMS-C was established at 44.5. The prevalence of stigma observed in the study population was 49.05%. Significant disparities were observed in the distribution of stigma across genders, with males experiencing more pronounced stigma than females. Moreover, patients consuming different primary substances reported diverse levels of stigma. Notably, those primarily using heroin endured a higher degree of stigma than users of other substances. CONCLUSION: The study is the first to identify a cut-off point for the SU-SMS-C by Naive Bayes classifier, bridging a major gap in stigma measurement research. SU-SMS-C may help treat and manage SUDs by reducing stigma.

12.
BMC Med Educ ; 24(1): 74, 2024 Jan 19.
Article de Anglais | MEDLINE | ID: mdl-38243257

RÉSUMÉ

BACKGROUND: Dropout and poor academic performance are persistent problems in medical schools in emerging economies. Identifying at-risk students early and knowing the factors that contribute to their success would be useful for designing educational interventions. Educational Data Mining (EDM) methods can identify students at risk of poor academic progress and dropping out. The main goal of this study was to use machine learning models, Artificial Neural Networks (ANN) and Naïve Bayes (NB), to identify first year medical students that succeed academically, using sociodemographic data and academic history. METHODS: Data from seven cohorts (2011 to 2017) of admitted medical students to the National Autonomous University of Mexico (UNAM) Faculty of Medicine in Mexico City were analysed. Data from 7,976 students (2011 to 2017 cohorts) of the program were included. Information from admission diagnostic exam results, academic history, sociodemographic characteristics and family environment was used. The main dataset included 48 variables. The study followed the general knowledge discovery process: pre-processing, data analysis, and validation. Artificial Neural Networks (ANN) and Naïve Bayes (NB) models were used for data mining analysis. RESULTS: ANNs models had slightly better performance in accuracy, sensitivity, and specificity. Both models had better sensitivity when classifying regular students and better specificity when classifying irregular students. Of the 25 variables with highest predictive value in the Naïve Bayes model, percentage of correct answers in the diagnostic exam was the best variable. CONCLUSIONS: Both ANN and Naïve Bayes methods can be useful for predicting medical students' academic achievement in an undergraduate program, based on information of their prior knowledge and socio-demographic factors. Although ANN offered slightly superior results, Naïve Bayes made it possible to obtain an in-depth analysis of how the different variables influenced the model. The use of educational data mining techniques and machine learning classification techniques have potential in medical education.


Sujet(s)
Étudiant médecine , Humains , Théorème de Bayes , Niveau d'instruction , Accomplissement ,
13.
Appl Spectrosc ; 78(4): 365-375, 2024 Apr.
Article de Anglais | MEDLINE | ID: mdl-38166428

RÉSUMÉ

Chylous blood is the main cause of unqualified and scrapped blood among volunteer blood donors. Therefore, a diagnostic method that can quickly and accurately identify chylous blood before donation is needed. In this study, the GaiaSorter "Gaia" hyperspectral sorter was used to extract 254 bands of plasma images, ranging from 900 nm to 1700 nm. Four different machine learning algorithms were used, including decision tree, Gaussian Naive Bayes (GaussianNB), perceptron, and stochastic gradient descent models. First, the preliminary classification accuracies were compared with the original data, which showed that the effects of the decision tree and GaussianNB models were better; their average accuracies could reach over 90%. Then, the feature dimension reduction was performed on the original data. The results showed that the effects of the decision tree were better with a classification accuracy of 93.33%. the classification of chylous plasma using different chylous indices suggested that the accuracies of the decision trees model both before and after the feature dimension reductions were the best with over 80% accuracy. The results of feature dimension reduction showed that the characteristic bands corresponded to all kinds of plasma, thereby showing their classification and identification potential. By applying the spectral characteristics of plasma to medical technology, this study suggested a rapid and effective method for the identification of chylous plasma and provided a reference for the blood detection technology to achieve the goal of reducing wasting blood resources and improving the work efficiency of the medical staff.


Sujet(s)
Algorithmes , Apprentissage machine , Humains , Théorème de Bayes , , Machine à vecteur de support
14.
Tohoku J Exp Med ; 262(1): 33-41, 2024 Jan 30.
Article de Anglais | MEDLINE | ID: mdl-37914284

RÉSUMÉ

As evidence of risk factors for severe cases of coronavirus disease 2019 (COVID-19) was uncertain in early phases of the pandemic, the development of an efficient predictive model for severe cases to triage high-risk individuals represented an urgent yet challenging issue. It is crucial to select appropriate statistical models when available data and evidence are limited. This study was conducted to assess the accuracy of different statistical models in predicting severe cases using demographic data from patients with COVID-19 prior to the emergence of consequential variants. We analyzed data from 929 consecutive patients diagnosed with COVID-19 prior to March 2021, including their age, sex, body mass index, and past medical histories, and compared areas under the receiver operating characteristic curve (ROC AUC) between different statistical models. The random forest (RF) model, deep learning (DL) models with not too many neurons, and naïve Bayes model exhibited AUC measures of > 0.70 with the validation datasets. The naïve Bayes model performed the best with the AUC measures of > 0.80. The accuracies in RF were more robust with narrower distribution of AUC measures compared to those in DL. The benefit of performing feature selection with a training dataset before building models was seen in some models, but not in all models. In summary, the naïve Bayes and RF models exhibited ideal predictive performance even with limited available data. The benefit of performing feature selection before building models with limited data resources depended on machine learning methods and parameters.


Sujet(s)
COVID-19 , Pandémies , Humains , Théorème de Bayes , COVID-19/épidémiologie , Indice de masse corporelle , Neurones
15.
J Neurosci Methods ; 403: 110026, 2024 03.
Article de Anglais | MEDLINE | ID: mdl-38029972

RÉSUMÉ

BACKGROUND: Self-grooming behavior in rodents serves as a valuable behavioral index for investigating stereotyped and perseverative responses. Most current grooming analyses rely on video observation, which lacks standardization, efficiency, and quantitative information about force. To address these limitations, we developed an automated paradigm to analyze grooming using a force-plate actometer. NEW METHOD: Grooming behavior is quantified by calculating ratios of relevant movement power spectral bands. These ratios are input into a naïve Bayes classifier, trained with manual video observations. The effectiveness of this method was tested using CIN-d mice, an animal model developed through early-life depletion of striatal cholinergic interneurons (CIN-d) and featuring prolonged grooming responses to acute stressors. Behavioral monitoring was simultaneously conducted on the force-place actometer and by video recording. RESULTS: The naïve Bayes approach achieved 93.7% accurate classification and an area under the receiver operating characteristic curve of 0.894. We confirmed that male CIN-d mice displayed significantly longer grooming durations than controls. However, this elevation was not correlated with increases in grooming force. Notably, the dopaminergic antagonist haloperidol reduced grooming force and duration. COMPARISON WITH EXISTING METHODS: In contrast to observation-based approaches, our method affords rapid, unbiased, and automated assessment of grooming duration, frequency, and force. CONCLUSIONS: Our novel approach enables fast and accurate automated detection of grooming behaviors. This method holds promise for high-throughput assessments of grooming stereotypies in animal models of neuropsychiatric disorders.


Sujet(s)
Comportement animal , Mouvement , Souris , Mâle , Animaux , Comportement animal/physiologie , Soins du pelage/physiologie , Théorème de Bayes , Halopéridol/pharmacologie , Rodentia
16.
Modern Hospital ; (6): 424-427, 2024.
Article de Chinois | WPRIM (Pacifique Occidental) | ID: wpr-1022296

RÉSUMÉ

Focusing on the issue that the naive Bayes model(NBM)in outpatient intelligent diagnosis,it is not effective to distinguish between different types of symptoms involved in a different range of subjects.An improved algorithm for the naive Bayes method is proposed,Introducing IDF factor,Provide different weights for different symptom types.First of all,based on authoritative medical literature,Collected and sorted the related corpus of diagnostics as a training data set,Then,based on the naive Bayes method,the priori probability and the class conditional probability are calculated,Trained the IDF factors for differ-ent symptoms,Finally,IDF factor is introduced to different combination of symptoms in classification judgment,to smoothed the different types of symptoms.In the accuracy comparison experiment of intelligent diagnosis,the recall rate of the improved algo-rithm is up about 11%,obviously higher than the naive Bayes method.

17.
Comput Methods Biomech Biomed Engin ; 27(3): 338-346, 2024 Mar.
Article de Anglais | MEDLINE | ID: mdl-36877167

RÉSUMÉ

Heart disease is one of the most dangerous diseases in the world. People with these diseases, most of them end up losing their lives. Therefore, machine learning algorithms have proven to be useful in this sense to help decision-making and prediction from the large amount of data generated by the healthcare sector. In this work, we have proposed a novel method that allows increasing the performance of the classical random forest technique so that this technique can be used for the prediction of heart disease with its better performance. We used in this study other classifiers such as classical random forest, support vector machine, decision tree, Naïve Bayes, and XGBoost. This work was done in the heart dataset Cleveland. According to the experimental results, the accuracy of the proposed model is better than that of other classifiers with 83.5%.This study contributed to the optimization of the random forest technique as well as gave solid knowledge of the formation of this technique.


Sujet(s)
Cardiopathies , Forêts aléatoires , Humains , Théorème de Bayes , Algorithmes , Apprentissage machine , Machine à vecteur de support
18.
Fa Yi Xue Za Zhi ; 39(5): 447-451, 2023 Oct 25.
Article de Anglais, Chinois | MEDLINE | ID: mdl-38006263

RÉSUMÉ

OBJECTIVES: To establish the menstrual blood identification model based on Naïve Bayes and multivariate logistic regression methods by using specific mRNA markers in menstrual blood detection technology combined with statistical methods, and to quantitatively distinguish menstrual blood from other body fluids. METHODS: Body fluids including 86 menstrual blood, 48 peripheral blood, 48 vaginal secretions, 24 semen and 24 saliva samples were collected. RNA of the samples was extracted and cDNA was obtained by reverse transcription. Five menstrual blood-specific markers including members of the matrix metalloproteinase (MMP) family MMP3, MMP7, MMP11, progestogens associated endometrial protein (PAEP) and stanniocalcin-1 (STC1) were amplified and analyzed by electrophoresis. The results were analyzed by Naïve Bayes and multivariate logistic regression. RESULTS: The accuracy of the classification model constructed was 88.37% by Naïve Bayes and 91.86% by multivariate logistic regression. In non-menstrual blood samples, the distinguishing accuracy of peripheral blood, saliva and semen was generally higher than 90%, while the distinguishing accuracy of vaginal secretions was lower, which were 16.67% and 33.33%, respectively. CONCLUSIONS: The mRNA detection technology combined with statistical methods can be used to establish a classification and discrimination model for menstrual blood, which can distignuish the menstrual blood and other body fluids, and quantitative description of analysis results, which has a certain application value in body fluid stain identification.


Sujet(s)
Liquides biologiques , Menstruation , Femelle , Humains , ARN messager/génétique , ARN messager/métabolisme , Théorème de Bayes , Modèles logistiques , Salive , Sperme , Génétique légale/méthodes
19.
Biomimetics (Basel) ; 8(6)2023 Sep 28.
Article de Anglais | MEDLINE | ID: mdl-37887588

RÉSUMÉ

During the pandemic of the coronavirus disease (COVID-19), statistics showed that the number of affected cases differed from one country to another and also from one city to another. Therefore, in this paper, we provide an enhanced model for predicting COVID-19 samples in different regions of Saudi Arabia (high-altitude and sea-level areas). The model is developed using several stages and was successfully trained and tested using two datasets that were collected from Taif city (high-altitude area) and Jeddah city (sea-level area) in Saudi Arabia. Binary particle swarm optimization (BPSO) is used in this study for making feature selections using three different machine learning models, i.e., the random forest model, gradient boosting model, and naive Bayes model. A number of predicting evaluation metrics including accuracy, training score, testing score, F-measure, recall, precision, and receiver operating characteristic (ROC) curve were calculated to verify the performance of the three machine learning models on these datasets. The experimental results demonstrated that the gradient boosting model gives better results than the random forest and naive Bayes models with an accuracy of 94.6% using the Taif city dataset. For the dataset of Jeddah city, the results demonstrated that the random forest model outperforms the gradient boosting and naive Bayes models with an accuracy of 95.5%. The dataset of Jeddah city achieved better results than the dataset of Taif city in Saudi Arabia using the enhanced model for the term of accuracy.

20.
PeerJ Comput Sci ; 9: e1626, 2023.
Article de Anglais | MEDLINE | ID: mdl-37869454

RÉSUMÉ

Electronic Health Records (EHRs) play a vital role in the healthcare domain for the patient survival system. They can include detailed information such as medical histories, medications, allergies, immunizations, vital signs, and more. It can help to reduce medical errors, improve patient safety, and increase efficiency in healthcare delivery. EHR approaches are proven to be an efficient and successful way of sharing patients' personal health information. These kinds of highly sensitive information are vulnerable to privacy and security associated threats. As a result, new solutions must develop to meet the privacy and security concerns in health information systems. Blockchain technology has the potential to revolutionize the way electronic health records (EHRs) are stored, accessed, and utilized by healthcare providers. By utilizing a distributed ledger, blockchain technology can help ensure that data is immutable and secure from tampering. In this article, a Hyperledger consortium network has been developed for sharing health records with enhanced privacy and security. The attribute based access control (ABAC) mechanism is used for controlling access to electronic health records. The use of ABAC on the network provides EHRs with an extra layer of security and control, ensuring that only authorized users have access to sensitive data. By using attributes such as user identity, role, and health condition, it is possible to precisely control access to records on blockchain. Besides, a Gaussian naïve Bayes algorithm has been integrated with this consortium network for prediction of cardiovascular disease. The prediction of cardiovascular is difficult due to its correlated risk factors. This system is beneficial for both patients and physicians as it allows physicians to quickly identify high-risk patients and easily provide them with patient severity level using feature weight prediction algorithms. Dynamic emergency access control privileges are used for the emergency team and will be withdrawn once the emergency has been resolved, depending on the severity score. The system is implemented with the following medical datasets: the heart disease dataset, the Pima Indian diabetes dataset, the stroke prediction dataset, and the body fat prediction dataset. The above datasets are obtained from the Kaggle repository. This system evaluates system performance by simulating various operations using the Hyperledger Caliper benchmarking tool. The performance metrics such as latency, transaction rate, resource utilization, etc. are measured and compared with the benchmark.

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