Ansiedade, estresse, sintomas de TDAH e desempenho em candidatos no exame da Ordem dos Advogados do Brasil/RS / Anxiety, stress, ADHD symptoms and performance in candidates in the Bar Exam of theBrazilian Bar Association/RS

A ansiedade e o estresse são fatores de risco para o desempenho em concursos públicos. Este estudo buscou verificar associações entre ansiedade, estresse, sintomas de TDAH e desempenho no XVIII Exame de Ordem Unificado da prova da OAB. Participaram 82 bacharéis em Direito, com média de idade de 32,5 anos. A maioria eram mulheres (54,9%), fizeram uso de medicação psiquiátrica (24,4%), repescagem (7,3%), não haviam prestado exame antes (30,5%), de uma a duas vezes (29,3%), de três a cinco vezes (31,7%) e acima de cinco vezes (8,5%). Foram aprovados (56,1%), e nestes, o ISSL apontou presença de estresse (65,2%), na fase da resistência (76,7%) com presença de sintomas psicológicos (70%). O BAI demonstrou ansiedade moderada (21,7%) e severa (13%), presença de sintomas de déficit de atenção (41,7%), de hiperatividade/impulsividade (33,3%) e de ambos (25%). Foram encontradas associações significativas entre idade e desempenho (p=0,021) e a presença de sintomas de estresse e desempenho (p=0,041).

Anxiety and stress are risk factors in public tender performances. This study aimed to verify associations among anxiety, stress, ADHD symptoms and the performance in XVIII Unified Order Exam from OAB test. Eighty-two Law bachelors, at the average age of 32,5 years old, took part in the study. Mosto f them were women (54,9%), made use of psychiatric medication (24,4%), repechage (7,3%), haven't taken the exam before (30,5%), from once to twice (29,3%), from three to five times (31,7%) and more than five times (8,5%). It was approved (56,1%), in which, the LSSI showed the presence of stress (65,2%), in resistance phase (76,7%) with the presence of psychological symptoms (70%). The BAI demonstrated moderate anxiety (21,7%) and severe (13%), had presence of attention disorder symptoms (41,7%), hyperactivity/ impulsiveness (33,3%) and both (25%). It was found significant associations among age and performance (p=0,021) and the presence of stress symptoms and performance (p=0,041).

Abdominopelvic kinesiotherapy for pelvic floor muscle training: a tested proposal in different groups.

INTRODUCTION AND HYPOTHESIS: This video's proposal was to present one of the pelvic floor muscle (PFM) training programs used in our research, and to study the effects of abdominopelvic kinesiotherapy on female PFM function. METHODS: A total of 82 women participated in this study, 11 nulliparous, 13 primiparous pregnant, 20 primiparous postpartum and 38 postmenopausal women, who were evaluated first by digital palpation, then by either electromyography or vaginal dynamometry to investigate their PFM strength, followed by ICIQ UI-SF and ICIQ-OAB to evaluate urinary symptoms. This intervention protocol lasted for 60 min, three times a week, with a total of 10 sessions, and was supervised by a physiotherapist, using a gym ball, according to Marques and collaborators. RESULTS: A significant increase in PFM strength was observed by digital palpation in all groups. This finding was confirmed by electromyography in both pregnant (p = 0.0001) and postpartum (p = 0.0001) groups, as well as in 20 of the 38 women from the postmenopausal group (p = 0.003) then by vaginal dynamometry (p = 0.02) in the rest of the women (18) from the same group, with a concomitant decrease in urinary symptoms (p < 0.05). CONCLUSION: The abdominopelvic kinesiotherapy program promotes an increase in pelvic floor muscle strength and a decrease in urinary symptoms.

The soluble guanylyl cyclase activator BAY 60-2770 ameliorates overactive bladder in obese mice.

PURPOSE: Activators of soluble guanylyl cyclase are of potential interest as treatment for cardiovascular diseases but to our knowledge they have never been proposed to treat overactive bladder. We evaluated the effects of the soluble guanylyl cyclase activator BAY 60-2270 on voiding dysfunction and detrusor overactivity in a mouse model of obesity associated overactive bladder. MATERIALS AND METHODS: C57BL/6 male mice fed for 10 weeks with standard chow or a high fat diet were treated with 1 mg/kg BAY 60-2770 per day for 2 weeks via gavage. Cystometric evaluations were done and responses to contractile agents in isolated bladders were determined. RESULTS: Obese mice showed an irregular micturition pattern characterized by significant increases in voiding and nonvoiding contractions, which were normalized by BAY 60-2770. Carbachol, KCl and CaCl2 produced concentration dependent contractions in isolated bladder strips, which were markedly greater in obese than in lean mice. BAY 60-2770 normalized bladder contractions in the obese group. A 78% increase in reactive oxygen species generation in the bladder tissue of obese mice was observed, which was unaffected by BAY 60-2770. Treatment with BAY 60-2770 generated a tenfold increase in cyclic guanosine monophosphate in the bladders of obese mice without affecting the nucleotide level in the lean group. Protein expression of the soluble guanylyl cyclase α1 and ß1 subunits was decreased 40% in the bladder tissue of obese mice but restored by BAY 60-2770. CONCLUSIONS: Two-week BAY 60-2770 therapy increased cyclic guanosine monophosphate and rescued expression of the soluble guanylyl cyclase α1 and ß1 subunits in bladder tissue, resulting in great amelioration of bladder dysfunction.

Correlation between body mass index and overactive bladder symptoms in pre-menopausal women / Correlação entre índice de massa corporal e sintomas de bexiga hiperativa em mulheres no menacme

Objective: The aim of the study was to establish a correlation between Overactive Bladder (OAB) symptoms and Body Mass Index (BMI) in women aged 20-45. Methods: We interviewed 1.050 women aged 20-45 in the area of Campinas, Brazil, to investigate the prevalence of overactive bladder symptoms. In this study, we used the ICIQ-OAB questionnaire (ICS standard), in its validated portuguese version and a specific questionnaire for the demographics, which includes information about BMI. Results: Overall, women with BMI ≥30 presented a significantly higher score than women with a lower BMI (18.5 - 24.9) (p=0.0066). In the analysis of individual symptoms, no significant differences were found regarding urinary frequency (p=0.5469). Women with BMI ≥30 presented more nocturia than women with BMI ranging between 18.5 and 24.9 (p=0.0154). Women in the group of BMI 25 - 29.9 presented more urgency than women with BMI 18.5 - 24.9 (p=0.0278). Significant difference was also found regarding urge-incontinence; women with BMI 25 - 29.9 presented a higher score than women in the group 18.5 - 24.9 (p= 0.0017). Analysis was also performed on the visual analogue scale regarding how much each symptom bothers the women (quality of life). There were no significant differences regarding frequency, nocturia or urgency but urgency incontinence bother was significant. Women with BMI 25 - 29.9 were more bothered by incontinence than women with BMI 18.5 - 24.9 (p=0.002). Conclusion: In conclusion, this study reinforces the correlation between BMI and OAB symptoms. Obese women present more OAB symptoms than non-obese women. .

Objetivo: O objetivo do estudo foi estabelecer uma correlação entre os sintomas de bexiga hiperativa e índice de massa corporal (IMC) em mulheres com idades entre 20 e 45 anos. Métodos: Foram entrevistadas 1.050 mulheres com idades entre 20 e 45 anos na região de Campinas, Brasil, para investigar a prevalência de sintomas de bexiga hiperativa. Neste estudo, foi utilizado o questionário ICIQ-OAB (padrão ICS), em sua versão validada em português e um questionário específico para os dados demográficos, que inclui informações sobre o IMC. Resultados: As mulheres com IMC ≥ 30 apresentaram uma pontuação significativamente maior do que as mulheres com IMC mais baixo (18,5 a 24,9); p = 0,0066. Na análise dos sintomas individuais, não foram encontradas diferenças significativas em relação a frequência urinária (p = 0,5469). Mulheres com IMC ≥ 30 apresentaram mais noctúria do que as mulheres com IMC variando entre 18,5 e 24,9 (p = 0,0154). As mulheres no grupo de IMC 25 a 29,9 apresentaram mais urgência do que as mulheres com IMC 18,5 a 24,9 (p = 0,0278). Também foi encontrada diferença significativa em relação à incontinência de urgência. As mulheres com IMC 25 a 29,9 apresentaram pontuação maior do que as mulheres no grupo 18,5 a 24,9 (p = 0,0017). A análise também foi realizada na escala analógica visual sobre quanto cada sintoma incomoda as mulheres (qualidade de vida). Não houve diferenças significativas em relação a frequência, noctúria e urgência, mas o incômodo causado pela incontinência de urgência foi significativo. Mulheres com IMC 25 a 29,9 foram mais incomodadas com a incontinência do que as mulheres com IMC 18,5 a 24,9 (p = 0,002). Conclusão: Em conclusão, este ...

Posterior tibial nerve stimulation vs parasacral transcutaneous neuromodulation for overactive bladder in children.

PURPOSE: Parasacral transcutaneous electrical nerve stimulation and posterior tibial nerve stimulation have emerged as effective methods to treat overactive bladder in children. However, to our knowledge no study has compared the 2 methods. We evaluated the results of parasacral transcutaneous electrical nerve stimulation and posterior tibial nerve stimulation in children with overactive bladder. MATERIALS AND METHODS: We prospectively studied children with overactive bladder without dysfunctional voiding. Success of treatment was evaluated by visual analogue scale and dysfunctional voiding symptom score, and by level of improvement of each specific symptom. Parasacral transcutaneous electrical nerve stimulation was performed 3 times weekly and posterior tibial nerve stimulation was performed once weekly. RESULTS: A total of 22 consecutive patients were treated with posterior tibial nerve stimulation and 37 with parasacral transcutaneous electrical nerve stimulation. There was no difference between the 2 groups regarding demographic characteristics or types of symptoms. Concerning the evaluation by visual analogue scale, complete resolution of symptoms was seen in 70% of the group undergoing parasacral transcutaneous electrical nerve stimulation and in 9% of the group undergoing posterior tibial nerve stimulation (p = 0.02). When the groups were compared, there was no statistically significant difference (p = 0.55). The frequency of persistence of urgency and diurnal urinary incontinence was nearly double in the group undergoing posterior tibial nerve stimulation. However, this difference was not statistically significant. CONCLUSIONS: We found that parasacral transcutaneous electrical nerve stimulation is more effective in resolving overactive bladder symptoms, which matches parental perception. However, there were no statistically significant differences in the evaluation by dysfunctional voiding symptom score, or in complete resolution of urgency or diurnal incontinence.