Metastatic Adenoid Cystic Carcinoma of the Bartholin Gland.

ABSTRACT: Adenoid cystic carcinoma (ACC) of the Bartholin gland is an exceedingly rare neoplasm. A 56-year-old woman with remote ACC resection (plus neoadjuvant chemoradiation and adjuvant chemotherapy) presented to an outside institution with shortness of breath. CT showed bilateral pulmonary nodules and mediastinal lymphadenopathy. With high clinical suspicion for metastatic disease, 18 F-FDG PET/CT was performed and showed scattered nodules with mild FDG uptake along with FDG-avid mediastinal, bilateral hilar, and bilateral cervical chain lymphadenopathy. Lung biopsy of a hypermetabolic nodule confirmed metastatic ACC.

Bartholin gland carcinoma in a young female: a rare disease in an unusual age group.

Primary Bartholin gland carcinoma (BGC) is an extremely rare disease. It typically presents in elderly women. It can be confused with Bartholin gland cyst, which is a benign condition leading to a delay in diagnosis and treatment. We are presenting a case report of BGC in a 35-year-old woman, which has created a diagnostic as well as therapeutic dilemma.

Solitary Vulvar Involvement of Ovarian Non-Hodgkin Lymphoma Mimicking Bartholin's Abscess on 18F-FDG PET/CT.

ABSTRACT: A 49-year-old woman was diagnosed with diffuse large B-cell lymphoma of the left ovary. Two months after the hysterectomy and bilateral salpingo-oophorectomy operation, the patient was referred to 18F-FDG PET/CT for staging. A mass lesion measuring 2.8 × 3 cm with intense 18F-FDG uptake was observed at right labium majus, which could be considered as a Bartholin's cyst or abscess. The lesion was excised, and non-Hodgkin lymphoma involvement of vulva was revealed by histopathology.

Surgical Treatment for Locally Advanced Adenoid Cystic Carcinoma of the Bartholin's Gland: A Case Report.

Adenoid cystic carcinoma (ACC) of the Bartholin's gland (BACC) is an extremely rare malignancy of the vulva. The characteristics of BACC include slow tumor growth and aggressive invasion, especially with perineural involvement. A 64-year-old Japanese woman complained of a mass and pain in the perineum. A 3 cm-sized mass was palpated inside of the labia majora. Diagnostic imaging demonstrated the tumor invading the anus and urethra. The patient underwent total pelvic exenteration with radical vulvectomy. Pathological findings revealed that the tumor was BACC. The surgical margin was positive for tumor cells, which necessitated adjuvant radiotherapy. No serious complications were associated with the surgery and radiotherapy. There is no clear consensus on to the proper surgical intervention in BACC. Achieving tumor-free surgical margins is desired to avoid recurrence. However, such attempts have often failed in reported BACC cases with extended surgical resection. Nevertheless, given the aggressive nature of BACC, extensive surgery including total pelvic exenteration is justified, particularly with promising reported efficacy of adjuvant radiotherapy on BACC prognosis.

Asymptomatic Bartholin Cyst: Evaluation With Multidetector Row Computed Tomography.

OBJECTIVE: The aim of this study was to determine the frequency, morphology, and attenuation characteristics of Bartholin cysts on multidetector computed tomography (MDCT) in asymptomatic women. METHODS: A total of 3280 consecutive MDCT examinations were assessed for Bartholin cysts. The diagnosis was based on shape, contrast enhancement, and anatomical location. Age, laterality, size, and attenuation patterns were recorded. Scans from patients with paravaginal-related symptoms were excluded, and any available follow-up MDCT scans or magnetic resonance images were evaluated. RESULTS: Asymptomatic Bartholin cysts were seen in 17 patients (0.52%) (mean age, 56 years). The mean maximum cyst diameter was 21.8 mm. High-attenuation cysts comprised 47% of cases, all in older (≥50 years) patients. Follow-up MDCT scans showed minimal changes over time. CONCLUSIONS: High-attenuation Bartholin cysts are more common than previously thought and are usually seen in older women. The size and attenuation of Bartholin cysts show only minimal changes over time.

MR findings of a giant Bartholin's duct cyst.

We describe the case of a 63-year-old woman with a large Bartholin's duct cyst that showed high signal intensity on T1- and T2-weighted magnetic resonance (MR) images. Although Bartholin's duct cyst is the most frequent cystic lesion of the vulva, such a giant cyst is rare.

Ultrasound imaging of Bartholin's cysts.

In a prospective, randomized study, Bartholin's cysts were depicted in 36 patients by means of ultrasound imaging. Patients were requested to return for a follow-up US examination after surgery. We were able to show that Bartholin's cysts can easily be expressed with ultrasonographic techniques. In clinical practice, this approach may not only help to improve diagnostics, but may also make therapy measurable and, for the first time, objectifiable.

Sonographic findings in Bartholin's gland hamartoma.

We report the case of a postmenopausal patient presenting with bilateral solid Bartholin's gland lesions. The clinical and sonographic features suggested a nonaggressive process, allowing the surgeon to choose excisional biopsy of 1 of the lesions rather than radical excision to establish the diagnosis of a Bartholin's gland hamartoma. To our knowledge, this is the first sonographic description of a benign solid Bartholin's gland lesion.

Bartholinitis after vulvovaginal surgery.

OBJECTIVES: The object of the study was to determine whether obstruction of the Bartholin gland duct after vulvovaginal surgery is a cause of Bartholin gland infections or cysts. STUDY DESIGN: The records of patients with vulvovaginal surgical procedures performed by me between 1983 and 1997 were reviewed for evidence of a Bartholin gland infection or cyst formation. RESULTS: A postoperative Bartholin gland infection occurred in 2 of 217 patients with posterior colporrhaphy (with or without vault suspension) and 1 of 14 patients with partial vestibulectomy for vestibulitis. No patient had a chronic Bartholin cyst develop. CONCLUSIONS: Bartholin gland infections and Bartholin cysts are uncommon occurrences after surgical procedures that have the potential to obstruct the Bartholin duct.

Magnetic resonance imaging and computed tomography appearance of asymptomatic paravaginal cysts.

The magnetic resonance imaging (MRI) and computed tomography (CT) appearance of 18 paravaginal cysts was reviewed. On MRI, serious cysts were hypointense on T1-weighted and hyperintense on T2-weighted images. Cysts presumed to contain proteinaceous material were hyperintense on T1-weighted and T2-weighted sequences while hemorrhagic cysts exhibited varying stages of hemorrhage. On CT, a high attenuation cyst was presumed to contain proteinaceous material or hemorrhage. MRI and CT examination may reveal paravaginal cysts; their varied appearance must be recognized to avoid confusion with other lesions.