Self-reported interoception, worries and protective behaviors during the COVID-19 pandemic: a longitudinal study

Background Protective behaviors were essential for minimizing the spread of the virus during the coronavirus disease 2019 (COVID-19) pandemic. It is often assumed that awareness of bodily sensations (interoception) can improve decision-making and facilitate adaptive behavior. Objective This paper investigates cross-sectional and longitudinal relationships between different aspects of self-reported interoception, trait anxiety, COVID-related worry, and health protective behaviors. Methods The study was conducted on a community sample of 265 adults. The two data collection phases took place online, before (baseline) and during the second wave of the COVID-19 pandemic in Hungary. Results Contrary to our expectations, neither cross-sectional nor longitudinal associations were found between protective behaviors and indicators of self-reported interoception. However, worry at baseline predicted protective behaviors during the second wave, even after controlling for socio-economical characteristics and protective behaviors at baseline. Conclusion Our results highlight the adaptivity of health-related worry when behavioral steps to avoid threats are known and available. Also, higher level of perceived interoception did not appear to be health protective under these circumstances. (AU)

Onset and Severity of Early Disruptive Behavioral Disorders in Treatment-Seeking Substance Use Disorder Patients with and without Attention-Deficit/Hyperactivity Disorder.

AIMS: This study addressed the age of onset of conduct disorder (CD) and oppositional defiant disorder (ODD) in treatment-seeking substance use disorder (SUD) patients with and without adult attention-deficit/hyperactivity disorder (ADHD) and its association with early onset of SUD. METHODS: We examined data from the 2nd International ADHD in Substance Use Disorders Prevalence Study, including 400 adults in SUD treatment from Puerto Rico, Hungary, and Australia. ADHD, SUD, and CD/ODD were assessed with the Conners Adult ADHD Diagnostic Interview for DSM-IV, the MINI International Neuropsychiatric Interview, and the K-SADS, respectively. Cox regression analyses modeled time to emergence of CD/ODD separately for SUD patients with and without adult ADHD. Linear regression models examined associations between age of onset of SUD and presence of ADHD and adjusted for sex, age, and country. To assess the mediating role of CD/ODD on the association of ADHD with onset of SUD, adjusted regression models were estimated. RESULTS: Treatment-seeking SUD patients with ADHD presented an earlier onset of CD/ODD compared with those without ADHD. CD/ODD symptom loads were higher among the SUD and ADHD group. Age of first substance use and SUD were significantly earlier in SUD patients with ADHD, and these findings remained significant after adjustment for demographics and coexisting CD/ODD. CONCLUSIONS: ADHD is associated with earlier onset of SUD as well as with an earlier onset of more frequent and more severe disruptive behavioral disorders. These findings may inform preventive interventions to mitigate adverse consequences of ADHD.

Prevalence of osteoporosis and osteopenia in men and premenopausal women with celiac disease: a systematic review.

BACKGROUND: Celiac disease (CD) is known as a reason of metabolic osteopathy. Progression of non-invasive methods such as bone densitometry has shown that an important ratio of CD cases is faced with impaired bone mass and such cases are prone to bone fractures. Variety of low bone mineral density in CD is probably because of ignored confounding factors such as age, menopause, and drug. The aim of our study was to systematically review the osteoporosis and osteopenia incidences among premenopausal females and males with CD. METHODS: This systematic review was done based on preferred reporting items for systematic reviews (PRISMA) guidelines. PubMed and Scopus and Cochran databases were searched according to the relevant medical subject headings (MeSH) of CD and bone mineral density until 2018. Prevalence of osteopenia and osteoporosis were used as effect size for meta-analysis. Cochrane Q (p < 0.05) and I2 index were presented to reveal the heterogeneity. RESULTS: 54 eligible full text reviews were included and nineteen selected for data extraction. Eleven articles didn't have our inclusion criteria and had ignored confounding factors like age and menopause, and we excluded; data extraction was done in eight studies. A total of 563 premenopausal women and men who were from, UK, Brazil, India, Hungary, and Poland were included. The pooled prevalence of osteoporosis was 14.4% [95%CI: 9-20.5%] (Cochrane Q = 7.889, p = 0.96, I2 = 49.29%), and osteopenia was 39.6% [31.1-48.8%] (Cochrane Q = 14.24, p = 0.07, I2 = 71.92%), respectively. CONCLUSION: Our findings suggest that bone loss is more prevalent in celiac disease and can be associated with increased risk of fracture. However, but results are pooled prevalence and we need more case -control studies with more sample size and consideration of confounding factors.

Genetic and environmental influence on thyroid gland volume and thickness of thyroid isthmus: a twin study

Objectives Decreased thyroid volume has been related to increased prevalence of thyroid cancer. Subjects and methods One hundred and fourteen Hungarian adult twin pairs (69 monozygotic, 45 dizygotic) with or without known thyroid disorders underwent thyroid ultrasound. Thickness of the thyroid isthmus was measured at the thickest portion of the gland in the midline using electronic calipers at the time of scanning. Volume of the thyroid lobe was computed according to the following formula: thyroid height*width*depth*correction factor (0.63). Results Age-, sex-, body mass index- and smoking-adjusted heritability of the thickness of thyroid isthmus was 50% (95% confidence interval [CI], 35 to 66%). Neither left nor right thyroid volume showed additive genetic effects, but shared environments were 68% (95% CI, 48 to 80%) and 79% (95% CI, 72 to 87%), respectively. Magnitudes of monozygotic and dizygotic co-twin correlations were not substantially impacted by the correction of covariates of body mass index and smoking. Unshared environmental effects showed a moderate influence on dependent parameters (24-50%). Conclusions Our analysis support that familial factors are important for thyroid measures in a general twin population. A larger sample size is needed to show whether this is because of common environmental (e.g. intrauterine effects, regional nutrition habits, iodine supply) or genetic effects.

Genetic and environmental influence on thyroid gland volume and thickness of thyroid isthmus: a twin study.

OBJECTIVES: Decreased thyroid volume has been related to increased prevalence of thyroid cancer. SUBJECTS AND METHODS: One hundred and fourteen Hungarian adult twin pairs (69 monozygotic, 45 dizygotic) with or without known thyroid disorders underwent thyroid ultrasound. Thickness of the thyroid isthmus was measured at the thickest portion of the gland in the midline using electronic calipers at the time of scanning. Volume of the thyroid lobe was computed according to the following formula: thyroid height*width*depth*correction factor (0.63). RESULTS: Age-, sex-, body mass index- and smoking-adjusted heritability of the thickness of thyroid isthmus was 50% (95% confidence interval [CI], 35 to 66%). Neither left nor right thyroid volume showed additive genetic effects, but shared environments were 68% (95% CI, 48 to 80%) and 79% (95% CI, 72 to 87%), respectively. Magnitudes of monozygotic and dizygotic co-twin correlations were not substantially impacted by the correction of covariates of body mass index and smoking. Unshared environmental effects showed a moderate influence on dependent parameters (24-50%). CONCLUSIONS: Our analysis support that familial factors are important for thyroid measures in a general twin population. A larger sample size is needed to show whether this is because of common environmental (e.g. intrauterine effects, regional nutrition habits, iodine supply) or genetic effects.

Serious eye injuries caused by bottles containing carbonated drinks.

AIM: To analyse serious eye injuries caused by bottles containing pressurised drinks. METHODS: Retrospective review of the databases of US, Hungarian, and Mexican eye injury registries. RESULTS: In the combined database (12 889 injuries), 90 cases (0.7%) were caused by bottle tops or glass splinters. The incidence varied widely: 0.3% (United States), 3.1% (Hungary), and 0.9% (Mexico), as did the agent. Champagne bottle corks were responsible in 20% (United States), 71% (Hungary; p<0.0001), and 0% (Mexico). Most eyes improved, but 26% remained legally blind. CONCLUSIONS: The presence of warning labels on champagne bottles appears to reduce cork related eye injuries, as does using plastic bottles and caps.

Epidemic cycles in agricultural populations: a cross-cultural study.

A cross-cultural analysis of mortality patterns is of interest to biological anthropologists and genetic epidemiologists. In this paper, we examine four agricultural populations from Costa Rica, Hungary, and the United States in order to determine if they suffered from a cyclical distribution of epidemics. When possible, we look at the mortality time series of adults and children separately. Of the 2 series, only 2 show significant epidemic cycles. Both are in the Hungarian groups and both affect subadults. Otherwise, the Costa Rica, U.S., and adult series of the Hungarian groups do not show any periodicity of mortality peaks. Our results indicate that epidemic cycles are not as ubiquitous in small agricultural groups as the literature would suggest.

[Prevalence of Carabelli's cusp in children 7-18 years old]. / A Carabelli-csücsök elófordulásának gyakorisága 7-18 éves gyerekeken.

The purpose of the study was to examine the prevalence of the Carabelli's cusp in children aged 7-18. 326 dental plaster casts of children undergoing orthodontic treatment in our department were examined. The incidence and degree of expression were investigated in the first upper permanent molars and scored according to Dahlberg's eight grade scale classification. Dental morphological characteristics provide information on phylogenic and genetic studies and understanding variations within and among species. Our results showed that the total incidence of the cusp was 65.34%.

Periodic abstinence and calendar method use in Hungary, Peru, the Philippines, and Sri Lanka.

Focus group research was conducted in four countries to understand how couples who use calendar methods determine when they are at risk of pregnancy, what behavior they adopt during the fertile phase, and whether or not they are satisfied with their method. Calendar and periodic abstinence method users do not all know how to make correct calendar calculations of the fertile period, report being sexually active during the fertile period, and desire a more comprehensive approach to sexual behavior during the fertile period. Men's roles in the methods should be enhanced, and credible resources in the community should be enlisted to improve education, information, and communication.

International variation in the incidence of hip fractures: cross-national project on osteoporosis for the World Health Organization Program for Research on Aging.

A cross-national study of hip fracture incidence was carried out in five geographic areas--Beijing, China; Budapest, Hungary; Hong Kong; Porto Alegre, Brazil; and Reykjavik, Iceland--during the years 1990-1992. Cases of hip fracture among women and men of age 20 years and older were identified using hospital discharge data in conjunction with medical records, operating room logs, and radiology logs. Estimated incidence rates varied widely, with Beijing reporting the lowest rates (age-adjusted rate per 100,000 population for men 20 years and older = 45.4; women = 39.6) and Reykjavik the highest rates (man = 141.3; women = 274.1). Rates were higher for women than for men in every area except Beijing. In every area except Budapest, review of the operating room or radiology logs identified additional cases that were not reported in the discharge list, increasing the estimated number of hip fractures by 11% to 62%, depending on the area. Review of medical records identified miscoding of hip fractures (ICD 9820) as 'shaft of femur and other femur fractures' (ICD 9821) in the discharge lists of every area except Budapest, increasing the estimated number of hip fractures by 1% to 30%. The final estimates of hip fracture incidence taking into account all investigated sources of undercount and overcount ranged from 15% lower to 89% higher than an estimate based on the discharge diagnoses alone. Although these results indicate substantial limitations in relying on hospital discharge data alone to estimate hip fracture incidence rates, the extent of errors found in the discharge lists is smaller than the large international variation found here and previously reported in incidence rates. The findings support the conclusion that the differences reported among countries mainly reflect genuine variation in the hip fracture incidence rates.

[Cardiovascular diseases. Comments on early mortality in Brazil]. / Doenças cardiovasculares. Comentários sobre a mortalidade precoce no Brasil.

PURPOSE: To compare age specific mortality rates from acute myocardial infarction and cerebrovascular diseases in Brazilian cities with equivalent death rates in other countries. METHODS: Data on Brazilian deaths were obtained from the Health Ministry's Mortality Information System. Data for other countries were obtained from a World Health Organization specialized publication. RESULTS: Nearly 50% of ischemic heart disease deaths among males occurred in men under 65. The equivalent proportion in other countries was 25%. The acute myocardial infarction death rate among men aged 35-44 was 3 times greater than in North America. The Brazilian cardiovascular disease death rates were also higher then in other countries. CONCLUSION: Contrary to what is usually believed, it is not only among old people that cardiovascular diseases are an important cause of death. This suggests that there is a need for specifically designed investigations that take account of the peculiarities of the Brazilian situation, as well as for urgent implementation of targetted risk factor control programs.

Doenças cardiovasculares: comentários sobre a mortalidade precoce no Brasil / Cardiovascular Diseases. Comments on Early Mortality in Brazil

Objetivo - Comparar coeficientes de mortalidade por infarto agudo do miocárdio (IAM) e doenças cerebrovasculares, específicos por idade em capitais situadas em regiöes metropolitanas do Brasil, às taxas de outros países. Métodos - Os dados de mortalidade das capitais brasileiras foram obtidos a partir do Sistema de Informaçäo de Mortalidade, do Ministério da Saúde. Os óbitos e taxas de mortalidade relativos aos outros países foram obtidos a partir de publicaçäo especializada da Organizaçäo Mundial de Saúde. Resultados - Nas capitais estudadas, cerca de 50 por cento dos ósbitos masculinos por doença isquêmica do coraçäo ocorreram no grupo etário menor de 65 anos de idade, enquanto em outros países, esta proporçäo situou-se em torno dos 25 por cento. O risco de morrer por IAM nos homens, entre 35 e 44 anos, foi 3 vezes mior do que o norte-americano. Os coeficientes de mortalidade por doenças cerebrovasculares também apresentaram maior magnitude em nosso meio, comparando-se aos outros países estudados. Conclusäo - Ao contrário do que se imagina, as enfermidades cardiovasculares näo constituem, no Brasil, causa de óbito importante apenas nos grupos mais idosos. Estes resultados sugerem a necessidade de investigaçäo específica em nosso meio, bem como a urgência da implantaçäo de programas de controle

The prevalence of oral health problems in participants of the 1992 Olympic Games in Barcelona.

The Olympic Games are the focus of attention for millions of people in the world and provide the pinnacle of sporting excellence. The health and welfare of the participating sportsmen and women is paramount for successful competition and this must include oral health. The purpose of this paper is to describe a study undertaken at the Barcelona Olympic Games in 1992 into the attendance patterns and oral health of patients visiting the dental clinic provided in the Olympic Village. Recommendations are made for the conduct of future dental care facilities at Olympic Games and the collection of data.