Ocular Sporotrichosis: 26 Cases with Bulbar Involvement in a Hyperendemic Area of Zoonotic Transmission.

PURPOSE: To describe 26 cases of bulbar conjunctival sporotrichosis. METHODS: Review of clinical records of patients with bulbar conjunctivitis due to culture-proven Sporothrix spp. infection, in Rio de Janeiro, from 2007 to 2017. RESULTS: Twenty-six patients were identified. Median age was 25 years. Adults were more affected (53.8%), followed by adolescents (26.9%). There was a predominance of women (73.1%). Twenty-four patients (96%) reported contact with cats with sporotrichosis. Twenty-one patients (80.8%) presented a primary ocular sporotrichosis. Five patients presented associated eyelid lesions, and 21 (80.8%) tarsal conjunctivitis. Parinaud oculoglandular syndrome was observed in 17 (81%) patients. Eight patients (36.4%) reported the use of steroid drops before diagnosis was made. All patients but one were treated with oral itraconazole. Twenty-three patients (88.5%) were completely cured and three (11.5%) were lost to follow-up. Eight patients (34.8%) developed ocular sequelae. CONCLUSION: Bulbar conjunctivitis is an important clinical presentation of ocular sporotrichosis. It can lead to ocular sequelae. Sporotrichosis should be considered in the differential diagnosis of ophthalmic external diseases, especially in patients with cat contact history.

Predictive clinical factors for ocular dryness in patients admitted to the Intensive Care Unit. / Fatores clínicos preditores para o ressecamento ocular em pacientes internados na Unidade de Terapia Intensiva.

OBJECTIVE: To evaluate the predictive clinical factors for ocular dryness and for the nursing diagnosis Risk for dry eye in the ocular surface of hospitalized adult patients in an intensive care unit. METHOD: A cross-sectional study was conducted between January and July 2016, with 206 patients (412 eyes). An inference about the presence of the diagnosis in the evaluated patients was performed by diagnostic nurses. The descriptive and inferential statistics subsidized the data analysis. RESULTS: 47.6% of the patients presented Risk for dry eye, and 52.4% were already diagnosed with ocular dryness. Statistical differences between the ocular dryness diagnosis in the right eye with hyperemia, mucous secretion, eyelid edema and lagophthalmia were identified. In addition, statistical differences were observed between hyperemia and eyelid edema with Risk for dry eye in the left eye and with the nursing diagnosis Risk for dry eye. CONCLUSION: Hyperemia, mucous secretion, eyelid edema and lagophthalmia are the predictive clinical factors for the nursing diagnosis Risk for dry eye and also of ocular dryness in the intensive care unit environment which deserve special attention in the preventive evaluation.

Colgajos o injertos cutáneos para la corrección de defectos palpebrales de gran tamaño / Flaps or cutaneous grafts for the correction of large eyelid defects

Objetivo: Describir los resultados estéticos y funcionales con el uso de colgajos o injertos cutáneos en la corrección de defectos palpebrales de gran tamaño. Métodos: Se realizó un estudio observacional, descriptivo, prospectivo, de 15 pacientes con lesiones tumorales o cicatrizales que provocaron defectos palpebrales de gran tamaño, desde enero a diciembre del año 2016, en la Consulta de Oculoplastia del Instituto Cubano de Oftalmología Ramón Pando Ferrer. Resultados: El 73,3 por ciento de los pacientes fue del sexo masculino y mayores de 60 años. Las lesiones tumorales representaron el 73,3 por ciento y el carcinoma basal el 53,3 por ciento. El párpado inferior fue el más comprometido. En el 60 por ciento de los casos se realizó colgajo cutáneo; de ellos, a 8 pacientes (88,8 por ciento) de tipo Tenzel. En el 73,3 por ciento de los pacientes no se presentaron complicaciones. El hematoma posquirúrgico fue la complicación general más frecuente (25 por ciento). Conclusiones: Los defectos palpebrales de gran tamaño se presentan en mayor cantidad en los pacientes mayores de 60 años, del sexo masculino. Predomina el carcinoma basal en el párpado inferior. La técnica reconstructiva con colgajos e injertos cutáneos resulta efectiva en la mayoría de los casos y se reporta un mínimo de complicaciones(AU)

Objective: To describe the esthetic and functional results of the use of flaps or cutaneous grafts for the correction of large eyelid defects. Method: A prospective, descriptive and observational study of 15 patients with tumoral or scar lesions that caused large eyelid defects was conducted from January to December, 2016 in the Oculoplasty Service of Ramon Pando Ferrer Cuban Institute of Ophthalmology. Results: In the study, 73.3 percent of patients were males aged over 60 years. Tumoral lesions were present in 73.3 percent of patients whereas basal carcinoma was found in 53.3 percent. The lower eyelid was the most affected. Sixty percent of cases were corrected with cutaneous flap, eight of them (88.8 percent) with Tenzel-type flap. No complications were seen in 73.3 percent of patients. Postsurgical hematoma was the most common complication (25 percent). Conclusions: Large eyelid defects were observed in a higher number of male patients aged 60 years. Basal carcinoma in the lower eyelid predominated. The reconstructive technique using flaps or cutaneous grafts proved to be effective in most of the cases, with minimal complications(AU)

Carcinoma de glándulas sebáceas del párpado / Sebaceous gland carcinoma of the eyelid

Los principales tumores malignos que afectan los párpados en orden de frecuencia son el carcinoma basocelular, el carcinoma de glándulas sebáceas, el carcinoma de células escamosas y el melanoma maligno. El carcinoma de glándulas sebáceas es una neoplasia originada en las glándulas sebáceas con predilección por cabeza y cuello, especialmente por las glándulas de Meibomio, aunque también puede afectar a las glándulas de Zeiss o ambas y su sitio de mayor presentación es en el párpado superior. Se presenta un paciente masculino de 46 años de edad quien presenta lesión pediculada y vascularizada en párpado inferior izquierdo posterior al drenaje de un supuesto chalazión. Se realiza rasurado de la lesión y recidiva por segunda ocasión. El carcinoma de células sebáceas se maneja con resección amplia y reconstrucción con técnica de Hughes(AU)

The main malignant tumors affecting the eyelids in an order of frequency are basal cell carcinoma, sebaceous gland carcinoma, squamous cell carcinoma and malignant melanoma. Sebaceous gland carcinoma is a neoplasm originating in sebaceous glands predominantly from the head and neck, particularly meibomian glands, though it may also affect the glands of Zeis or both, and its most common site of presentation is the upper eyelid. A 46-year-old male patient presents with a pediculated vascularized lesion on his lower left eyelid after drainage of a supposed chalazion. The lesion was shaved off and reoccurred a second time. Sebaceous cell carcinoma is managed with broad resection and reconstruction by Hughes' technique(AU)

Frequência de ocorrência das afecções dos anexos oculares e do olho externo / Frequency of occurrence of affections of the adnexa and external eye

RESUMO Objetivo: Observar a frequência de ocorrência das afecções que acometem os anexos oculares e o olho externo, assim como descrever o perfil demográfico dos portadores, na região centro oeste do estado de São Paulo. Métodos: Estudo prospectivo, populacional e aleatorizado, no qual foram avaliadas 11.000 pessoas da região centro-oeste do Estado de São Paulo, nos anos de 2004/2005, por meio de consultas oftalmológicas e utilizando uma unidade móvel. Foi realizado exame oftalmológico completo. Os dados foram transferidos para tabela Excel, utilizando-se para o presente estudo dados referentes aos anexos e doenças do olho externo. A frequência de ocorrência dos problemas detectados foi analisada estatisticamente. Resultados: Foram detectadas 1.581 (14,6%) afecções de anexos ou do olho externo, sendo as mais frequentes o pterígio (9,4%), o hordéolo (0,8%) e as alterações do posicionamento palpebral (1,7%) (ectrópio, ptose e triquíase). Trauma, ectrópio e pterígio foram estatisticamente mais frequentes na população masculina. Conclusão: Das afecções pesquisadas, a de maior ocorrência na população foi o pterígio, seguido das alterações inflamatórias e do posicionamento palpebral.

ABSTRACT Purpose: To observe the frequency of occurrence of affections involving the adnexa or the external eye, as well as to describe the demographic profile of patients. Methods: A prospective, population based, randomized study was done in the Midwest region of the state of São Paulo, in the years 2004/2005. Using a Mobile Ophthalmic Unit we evaluated 11,000 people. A comprehensive eye exam was performed. Data were transferred to excel table and for this study we used information relating to annexes and external eye diseases. The frequency of occurrence of the problems detected was statistically analyzed. Results: We identified 1,581(14.4%) disorders in the adnexa or in the external eye. The most common disorders were pterygium (9.4%), hordeolum (0.8%) and changes in eyelid position (1.7%) (ectropion, ptosis and trichiasis). Trauma, ectropion and pterygium were statistically more frequent in the male population. Conclusion: Of the surveyed disorders the most frequent in the population was pterygium, followed by inflammatory changes and alterations in the eyelid position.

Sporotrichosis in the Ocular Adnexa: 21 Cases in an Endemic Area in Peru and Review of the Literature.

PURPOSE: To describe the clinical and epidemiologic characteristics of sporotrichosis in ocular adnexa and give an insight into factors associated with this condition. DESIGN: Retrospective case series and literature review. METHODS: We retrospectively reviewed all cases of sporotrichosis in ocular adnexa between 2004 and 2014 in the Santa Teresa Clinic of Abancay, Peru and reviewed all case reports of sporotrichosis in ocular adnexa in the literature. RESULTS: We reviewed records of 21 patients with sporotrichosis in ocular adnexa; 12 (57.1%) of them were male and their median age surrounded 9 years. In our series, 19 patients had lesions in the eyelids and 2 in the eyebrows. The lymphocutaneous form occurred in 62% of them. Ten patients (47.6%) were cured with potassium iodide. Among 65 patients with sporotrichosis in ocular adnexa (our 21 patients and 44 from the literature), the average age was 9 years, and 78% were ≤15 years of age; 54% were male. The lesions were more frequent on the eyelids (n = 53 [82%]), followed by the lacrimal gland (n = 5), conjunctiva (n = 4), and eyebrows (n = 3). The lymphocutaneous clinical form (54%) was the most frequent. Fifty patients were cured: 31 of them with potassium iodide, 16 with itraconazole, and 3 with a combination including potassium iodide, itraconazole, and fluconazole. Twenty-nine patients (44.6%) resided in a hyperendemic region, and 5 patients reported contact with cats that had sporotrichosis. CONCLUSIONS: Sporotrichosis in ocular adnexa is associated with children ≤15 years of age, and in 82% of these cases the disease is limited to the eyelids.

Alterações palpebrais: frequência de ocorrência e perfil dos portadores em amostra populacional brasileira / Eyelid disorders: frequency of occurrence and profile of carriers in a Brazilian population sample

Objetivo: Apresentar a frequência de ocorrência das alterações palpebrais em uma amostra populacional brasileira, assim como as características de seus portadores. Métodos: Estudo transversal utilizando amostra populacional aleatorizada, realizado nos anos de 2004/2005, em nove cidades da região centro-oeste do estado de São Paulo. Foram examinadas 7654 pessoas sendo os participantes avaliados segundo variáveis demográficas e exame oftalmológico completo. As alterações palpebrais foram avaliadas por meio de exame externo usando lanterna e lâmpada de fenda. Os dados obtidos foram analisados estatisticamente. Resultados: As alterações palpebrais como a triquíase e o ectrópio foram mais relacionadas às características homens, brancos, queixa de redução de acuidade visual para perto. Foi realizado tratamento cirúrgico em 72,7% das triquíases detectadas, assim como 28,5% dos ectrópios. Já os casos de ptose palpebral foram relacionados ao sexo feminino, brancas, com queixa de diminuição da acuidade visual para perto e 26,3% necessitaram de cirurgia. Entrópio foi detectado em um caso, masculino, branco e epibléfaro foi observado em um indivíduo do sexo feminino, parda. Conclusão: A alteração palpebral mais presente na população geral brasileira é a triquíase, seguida da ptose palpebral e do ectrópio. Os autores chamam a atenção para o fato de os portadores não possuírem queixas relacionadas às alterações palpebrais.

Purpose: to show the frequency of occurrence of the eyelid disorders in a Brazilian population sample, as well as the characteristics of the carriers. Methods: a transversal study using a random population sample was carried out in the years 2004/2005, involving nine cities of the middle west region of the State of São Paulo - Brazil. We had 7654 participants which were evaluated according to demographic variables and complete ophthalmological examination. The eyelid disorders were detected using a lantern and slit lamp. Data were statistically analyzed. Results: eyelid disorders such as of trichiasis and ectropion were more related to the characteristics men, whites, complaining of reduced near visual acuity and 72.7% of trichiasis underwent surgical treatment, as well as 28.5% of patients with ectropion. Ptosis was related to the females, whites, complaining of reduced near visual acuity and 26.3% required surgery. Entropion was detected only in one case, male, white and a case of epiblepharon was observed in a female, brown. Conclusion: the most frequent palpebral disorder observed in the Brazilian general population is trichiasis, followed by ptosis and ectropion. The authors call attention to the fact that carriers do not have complaints related to the eyelid disorders.

Aspectos epidemiológicos das lesões pseudoneoplásicas e benignas da pálpebra na região de Botucatu - São Paulo / Eyelid pseudoneoplasic and benign lesions at Botucatu region - epidemiological aspects

Objetivo: Conhecer as características das lesões palpebrais pseudoneoplásicas e benignas em nossa região. Local: Faculdade de Medicina de Botucatu - São Paulo. Método: Estudou-se a ocorrência das lesões palpebrais pseudoneplásicas, benignas da pele e dos anexos, na Faculdade de Medicina de Botucatu - UNESP, no período de 1989 a 1999, avaliando-se a idade, o sexo, a faixa etária, a localização da lesão e os diagnósticos clínico e histopatológico. Resultados: No período estudado, foram removidas e tiveram confirmação diagnóstica, através de exame histopatológico, 311 lesões: 169 (54,34 por cento) lesões pseudoneoplásicas, 114 (36,66 por cento) lesões benignas da pele e 28 (9,00 por cento) lesões benignas derivadas de anexos cutâneos. A maioria dos pacientes apresentava mais de 40 anos (66,88 por cento) e o sexo feminino foi o mais acometido (65,27 por cento). As lesões pseudoneoplásicas e as benignas predominaram na pálpebra superior, enquanto as lesões anexiais não apresentaram localização preferencial. Conclusão: Encontramos 54,34 por cento de lesões pseudoneoplásicas, 36,66 por cento de lesões benignas da pele e 9,00 por cento de lesões benignas derivadas de anexos cutâneos. As mulheres foram as mais acometidas e a localização mais freqüente foi a pálpebra superior. O exame anatomo-patológico foi importante para a determinação do diagnóstico correto e deve ser realizado mesmo que a suspeita seja de lesão benigna.

Prevalence of bacteria in the conjunctival sac and on the eyelid margin of clinically normal cats.

Samples from the palpebral conjunctive, third eyelid and eyelid margin from 50 asymptomatic cats were analysed. Sixty-seven per cent of the samples showed bacterial growth with a high predominance of the genus Staphylococcus (97.8 per cent). The most frequent species was S epidermidis (45.7 per cent), followed by S simulans (23.9 per cent), S auricularis (17.4 per cent) and S saprophyticus (6.5 per cent). Three samples of S aureus (6.5 per cent) and one of Pseudomonas aeruginosa (2.1 per cent) were also identified. The role of these microorganisms in the eyes of cats is discussed and the importance of the new species Staphylococcus felis is stressed.

Ocular findings in Down's syndrome.

PURPOSE: To identify the most common ocular findings in a pediatric group of patients with Down's syndrome. METHODS: A total of 152 children with Down's syndrome between two months and 18 years of age prospectively underwent ocular examination, including visual acuity assessment, slit-lamp biomicroscopy, ocular motility, cycloplegic retinoscopy, and ophthalmoscopy. RESULTS: Ocular findings in decreasing prevalence were the following: upward slanting of the palpebral fissure with the outer canthus 2 mm or higher than the inner canthus (82%), epicanthal folds (61%), astigmatism (60%), iris abnormalities (52%), strabismus (38%), lacrimal system obstruction (30%), blepharitis (30%), retinal abnormalities (28%), hyperopia (26%), amblyopia (26%), nystagmus (18%), cataract (13%), and myopia (13%). Visual acuity was assessed, and the Teller acuity cards were the most useful method of examination. The patients younger than five years old had a higher prevalence of hyperopia than did those in other age groups; patients between five and 12 years old had a higher prevalence of astigmatism; and patients older than 12 years of age had more iris abnormalities, strabismus, and cataract. Myopia and myopic astigmatism were more common in the patients with cardiac malformations. CONCLUSION: The early diagnosis of the ocular abnormalities in patients with Down's syndrome, by using Teller acuity cards in assessing visual acuity facilitates the treatment of refractive errors, strabismus, and amblyopia and may minimize handicaps.

Lesöes benignas e pseudo neoplasicas da palpebra na Faculdade de Medicina de Botucatu / Lid benign and pseudoneoplastic lesions in Botucatu Medical School

Estudou-se a ocorrência de lesöes pseudoneoplásicas e lesöes benignas da pele e anexos palpebrais na Faculdade de Medicina de Botucatu de 1978 a 1988. Encontrou-se 128 casos que tiveram confirmaçäo diagnóstica através de exame histopatológico: 81 (63,28//) lesöes pseudoneoplásicas, 31 (24,21//) lesöes benignas da pele e 16 (12,50//) lesöes benignas de anexos cutâneos. Nos 3 grupos de lesöes o sexo feminino foi o mais acometido. Lesöes pseudoneoplásicas e benignas da pele ocorreram mais na pálpebra superior e lesöes anexiais, näo tiveram localizaçäo preferencial. Os autores chamam a atençäo para a importância de submeter o material excisado a exame histopatológico, pois o diagnóstico clínico foi incorreto em muitos casos