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1.
Arch Dermatol Res ; 316(8): 530, 2024 Aug 17.
Article de Anglais | MEDLINE | ID: mdl-39153084

RÉSUMÉ

Patients' experience accessing dermatologic care is understudied. The purpose of this cross-sectional study was to examine current wait times for new patients to receive dermatological care in NYC. Websites at 58 accredited private and public hospitals in the five boroughs of NYC were reviewed to identify dermatology practices. Office telephone numbers listed on each website were called to collect information pertaining to whether the physician was accepting new patients, type of insurance accepted (public, private, both, or none), and the number of days until a new patient could be seen for an appointment. Data pertaining to the time kept on hold and availability of web-based booking were also collected. Mean waiting time for an appointment was 50 days [standard deviation, SD 66] - nearly 2 months, but the distribution was considerably skewed. The median waiting time was 19.5 days [Interquartile range, IQR 4-60]. The time kept on hold to make the appointment was negligible at about 1 min (63 s, SD = 77) but could take up to ~ 7 min. Two-thirds of dermatologists accepted private, Medicare, and Medicaid insurance (n = 228, 66%); a small number accepted only private insurance (n = 12, 4%) or no insurance at all (n = 16, 5%). The median waiting time for an appointment for the 228 providers that accepted Medicaid was 30.5 days (IQR = 5.0-73.25) while for providers who did not accept Medicaid (n = 116) the median wait time for an appointment was 13.0 days (IQR = 3.0-38.0). Just over half (56%) of the dermatologists allowed for appointments to be booked on their website (n = 193). This research highlights the necessity of incorporating new strategies into routine dermatology appointments in order to increase treatment availability and decrease healthcare inequality.


Sujet(s)
Rendez-vous et plannings , Dermatologues , Listes d'attente , Humains , Études transversales , New York (ville) , Dermatologues/statistiques et données numériques , Facteurs temps , Dermatologie/statistiques et données numériques , États-Unis , Accessibilité des services de santé/statistiques et données numériques , Medicaid (USA)/statistiques et données numériques , Medicare (USA)/statistiques et données numériques
2.
JCO Clin Cancer Inform ; 8: e2400094, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-39159422

RÉSUMÉ

PURPOSE: No consensus about the effectiveness of prostate-specific antigen (PSA) screening exists among clinical guidelines, especially for the elderly. Randomized trials of PSA screening have yielded different results, partly because of variations in adherence, and it is unlikely that new trials will be conducted. Our objective was to estimate the effect of annual PSA screening on prostate cancer (PC) mortality in Medicare beneficiaries age 67-84 years. METHODS: This is a large-scale, population-based, observational study of two screening strategies: annual PSA screening and no screening. We used data from 537,599 US Medicare (2001-2008) beneficiaries age 67-84 years who had a good life expectancy, no previous PC, and no PSA test in the 2 years before baseline. We estimated the 8-year PC mortality and incidence, treatments for PC, and treatment complications of PSA screening. RESULTS: In men age 67-74 years, the estimated difference in 8-year risk of PC death between PSA screening and no screening was -2.3 (95% CI, -4.1 to -1.1) deaths per 1,000 men (a negative risk difference favors screening). Treatment complications were more frequent under PSA screening than under no screening. In men age 75-84 years, risk difference estimates were closer to zero. CONCLUSION: Our estimates suggest that under conventional statistical criteria, annual PSA screening for 8 years is highly compatible with reductions of PC mortality from four to one fewer PC deaths per 1,000 screened men age 67-74 years. As with any study using real-world data, the estimates could be affected by residual confounding.


Sujet(s)
Dépistage précoce du cancer , Medicare (USA) , Antigène spécifique de la prostate , Tumeurs de la prostate , Humains , Mâle , Sujet âgé , Antigène spécifique de la prostate/sang , États-Unis/épidémiologie , Tumeurs de la prostate/mortalité , Tumeurs de la prostate/diagnostic , Sujet âgé de 80 ans ou plus , Dépistage précoce du cancer/méthodes , Dépistage de masse/méthodes , Incidence
5.
J Med Econ ; 27(1): 1076-1085, 2024.
Article de Anglais | MEDLINE | ID: mdl-39102473

RÉSUMÉ

AIMS: Fruquintinib is a selective small molecule tyrosine kinase inhibitor of vascular endothelial growth factor receptor (VEGFR)-1, -2, and -3 recently approved in the United States (US) for the treatment of adult patients with metastatic colorectal cancer (CRC) who have previously been treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type and medically appropriate, anti-epidermal growth factor receptor therapy. This study aimed to estimate the 5-year budget impact of fruquintinib from a US payer perspective (commercial and Medicare). MATERIALS AND METHODS: A budget impact model was developed to compare two scenarios: a reference scenario in which patients received regorafenib, trifluridine/tipiracil, or trifluridine/tipiracil with bevacizumab and an alternative scenario in which patients received reference scenario treatments or fruquintinib. Market shares were evenly divided across available options. A 5-year time horizon and a hypothetical health plan of 1 million members was assumed. The model included epidemiological inputs to estimate the eligible population; clinical inputs for treatment duration, progression-free survival, overall survival, and adverse event (AE) frequency; and cost inputs for treatment, AEs, disease management, subsequent therapy, and terminal care costs. Budget impact was reported as total, per member per year (PMPY), and per member per month (PMPM). RESULTS: The model estimated an eligible population of 194 patients (39 per year) over 5 years. In the base case, the estimated 5-year budget impact of fruquintinib was $4,077,073 ($0.82 PMPY and 0.07 PMPM) for a commercial health plan. During the first year, the estimated budget impact was $627,570 ($0.63 PMPY and 0.05 PMPM). Results were robust across sensitivity analyses. PMPM costs from the Medicare perspective were greater than the base-case (commercial) ($0.17 vs. $0.07) due to higher incidence of CRC in that population. CONCLUSIONS: Fruquintinib is associated with a low budget impact for payers based on proposed thresholds in the US.


Fruquintinib is a treatment for metastatic colorectal cancer that has progressed after or not responded to multiple guideline-recommended therapies. This budget impact analysis was conducted to estimate the added costs a health plan would incur over a 5-year period if it chose to cover this therapy. The analysis found that the per plan member per month cost of covering fruquintinib was $0.07 for a United States commercial health plan and $0.17 for Medicare.


Sujet(s)
Protocoles de polychimiothérapie antinéoplasique , Benzofuranes , Bévacizumab , Tumeurs colorectales , Pyridines , Thymine , Humains , Tumeurs colorectales/traitement médicamenteux , Benzofuranes/usage thérapeutique , Benzofuranes/économie , États-Unis , Bévacizumab/usage thérapeutique , Bévacizumab/économie , Protocoles de polychimiothérapie antinéoplasique/usage thérapeutique , Protocoles de polychimiothérapie antinéoplasique/économie , Pyridines/usage thérapeutique , Pyridines/économie , Trifluorothymidine/usage thérapeutique , Trifluorothymidine/économie , Budgets , Quinazolines/usage thérapeutique , Quinazolines/économie , Phénylurées/usage thérapeutique , Phénylurées/économie , Uracile/analogues et dérivés , Uracile/usage thérapeutique , Uracile/économie , Composés organiques du platine/usage thérapeutique , Composés organiques du platine/économie , Analyse coût-bénéfice , Camptothécine/analogues et dérivés , Camptothécine/usage thérapeutique , Camptothécine/économie , Antinéoplasiques/économie , Antinéoplasiques/usage thérapeutique , Irinotécan/usage thérapeutique , Irinotécan/économie , Medicare (USA) , Fluorouracil/usage thérapeutique , Fluorouracil/économie , Oxaliplatine/usage thérapeutique , Oxaliplatine/économie , Récepteurs aux facteurs de croissance endothéliale vasculaire , Modèles économiques , Association médicamenteuse , Pyrrolidines
6.
Epilepsy Res ; 205: 107427, 2024 Sep.
Article de Anglais | MEDLINE | ID: mdl-39116513

RÉSUMÉ

OBJECTIVE: We described patterns and trends in ED use among adults with epilepsy in the United States. METHODS: Utilizing inpatient and ED discharge data from seven states, we conducted a cross-sectional analysis to identify adult ED visits diagnosed with epilepsy or seizures from 2010 to 2019. Using ED visit counts and estimates of state-level epilepsy prevalence, we calculated ED visit rates overall and by payer, condition, and year. RESULTS: Our data captured 304,935 ED visits with epilepsy as a primary or secondary diagnosis in 2019. Across the seven states, visit rates ranged between 366 and 726 per 1000 and were higher than rates for adults without epilepsy in all states but one. ED visit rates were highest among Medicare and Medicaid beneficiaries (vs commercial or self-pay). Adults with epilepsy were more likely to be admitted as inpatients. Visits for nervous system disorders were 6.3-8.2 times higher among people with epilepsy, and visits for mental health conditions were 1.2-2.6 times higher. Increases in ED visit rates from 2010 to 2019 among people with epilepsy exceeded increases among adults without by 6.0-27.3 percentage points. CONCLUSION: Adults with epilepsy visit the ED frequently and visit rates have been increasing over time. These results underscore the importance of identifying factors contributing to ED use and designing tailored interventions to improve ambulatory care quality.


Sujet(s)
Service hospitalier d'urgences , Épilepsie , Medicaid (USA) , Humains , Service hospitalier d'urgences/statistiques et données numériques , Études transversales , Épilepsie/épidémiologie , Épilepsie/thérapie , Mâle , Adulte , Femelle , États-Unis/épidémiologie , Adulte d'âge moyen , Sujet âgé , Medicaid (USA)/statistiques et données numériques , Jeune adulte , Medicare (USA)/statistiques et données numériques , Adolescent , Acceptation des soins par les patients/statistiques et données numériques , Hospitalisation/statistiques et données numériques , Hospitalisation/tendances
7.
JAMA Netw Open ; 7(8): e2425627, 2024 Aug 01.
Article de Anglais | MEDLINE | ID: mdl-39150712

RÉSUMÉ

Importance: Reduced institutional postacute care has been associated with savings in alternative payment models. However, organizations may avoid voluntary participation if participation could threaten their own revenues. Objective: To characterize the association between hospital-skilled nursing facility (SNF) integration and participation in Medicare's Bundled Payments for Care Improvement Advanced (BPCI-A) program. Design, Setting, and Participants: This is a cross-sectional analysis of hospital participation in BPCI-A beginning with its launch in 2018. Each SNF-integrated hospital was matched with 2 nonintegrated hospitals for each of 4 episode-specific analyses. Fifteen hospital-level variables were used for matching: beds, case mix index, days, area SNF beds, metropolitan location, ownership, region, system membership, and teaching status. Hospitals were also matched on episode-specific volume, target price, and the interaction of target price and case mix. Episode-specific logistic models were estimated regressing hospital participation on integration and the previously listed variables. The marginal effect of integration on participation was then calculated. Analysis took place from August 2022 to May 2024. Exposure: Hospital-SNF integration, as defined by common ownership and referral patterns and identified using cost reports, Medicare claims, and Provider Enrollment, Chain, and Ownership System records. Additional sources included records of target prices and participation, the Area Health Resources File, and the Compendium of US Health Systems. Main Outcomes and Measures: Participation in BPCI-A. Results: In total, 1524 hospitals met criteria for inclusion in the hip and femur (HFP) analysis, 1825 were included in the major joint replacement of the lower extremity (MJRLE) analysis, 2018 were included in the sepsis analysis, and 1564, were included in the stroke-specific analysis. Across episodes, 191 HFP-eligible hospitals (12.5% of HFP-eligible hospitals), 302 MJRLE-eligible hospitals (16.5%), 327 sepsis-eligible hospitals (16.2%), and 185 sepsis-eligible hospitals (11.8%) were SNF integrated. In total, 79 hospitals (5.2%) participated in the HFP episode, 128 (7.0%) participated in the MJRLE episode, 204 (10.1%) participated in the sepsis episode, and 141 (9.0%) participated in the stroke episode. Integration was associated with a 4.7-percentage point decrease (95% CI, 2.4 to 6.9 percentage points) in participation in the MJRLE episode. There was no association between integration and participation for HFP (0.5-percentage point increase in participation moving from nonintegrated to integrated; 95% CI, -2.9 to 3.8 percentage points), sepsis (1.0-percentage point increase; 95% CI, -2.2 to 4.2 percentage points), and stroke (0.3-percentage point decrease; 95% CI, -3.1 to 3.8 percentage points). Conclusions and Relevance: In this cross-sectional study, there was an uneven association between hospital-SNF integration and participation in Medicare's BPCI-A program. Other factors may be more consistent determinants of selection into voluntary payment reform.


Sujet(s)
Medicare (USA) , Établissements de soins qualifiés , États-Unis , Humains , Études transversales , Medicare (USA)/économie , Établissements de soins qualifiés/économie , Établissements de soins qualifiés/statistiques et données numériques , Bouquets de soins des patients/économie , Hôpitaux/statistiques et données numériques , Mécanismes de remboursement
8.
Health Care Manage Rev ; 49(4): 254-262, 2024.
Article de Anglais | MEDLINE | ID: mdl-39102338

RÉSUMÉ

BACKGROUND: Rising health care costs and consequent increases in Medicare reimbursements have led to many payment reforms over the years. Implementation of the prospective payment system (PPS) for hospitals in 1983 incentivized hospitals to either purchase skilled nursing facilities (SNFs) or utilize their excess capacity to establish one within the hospital. With PPS reimbursement being applied to SNFs in 1998, prior monetary incentives for hospitals to own an SNF disappeared. However, despite the reduction in numbers, many hospitals continued to operate their hospital-based skilled nursing facilities (HBSNFs). PURPOSE: This study examines the organizational and market-level factors associated with the survival of HBSNFs using the population ecology of organizations framework. METHODOLOGY: Using American Hospital Association survey data, event histories of all U.S. acute care hospitals with an open HBSNF in 1998 were plotted to examine if a hospital closed its HBSNF during a 22-year period (1998-2020). The primary independent variables included hospital size, ownership, total margin, market competition, and Medicare Advantage penetration. The independent and control variables were lagged by 1 year. Cox regressions were conducted to estimate the hazard ratios capturing the risk of HBSNF closure. RESULTS: The results showed that HBSNFs located in large, not-for-profit hospitals and those operating in less competitive markets had greater odds of surviving. PRACTICE IMPLICATIONS: The HBSNF administrators of small, for-profit hospitals and those operating in highly competitive markets could utilize the findings of this study to judiciously allocate slack resources to their HBSNFs to keep those open given the current emphasis on continuity of care by regulatory bodies.


Sujet(s)
Système de paiements préétablis , Établissements de soins qualifiés , Établissements de soins qualifiés/organisation et administration , Humains , États-Unis , Medicare (USA) , Concurrence économique , Hôpitaux/statistiques et données numériques , Propriété
9.
BMC Geriatr ; 24(1): 648, 2024 Aug 01.
Article de Anglais | MEDLINE | ID: mdl-39090545

RÉSUMÉ

BACKGROUND: Physical function is an important indicator of physical health and predicts mortality. This study identified characteristics associated with limitations in Medicare recipients' activities of daily living. METHODS: 2019 Consumer Assessment of Healthcare Providers and Systems Fee-for-Service Medicare Survey data: 79,725 respondents (34% response rate) who were 65 and older and 53% female; 7% Black, 5% Hispanic, 4% Asian American, Native Hawaiian, or other Pacific Islander, 2% Multiracial, 1% American Indian/Alaskan Native; 35% with high school education or less. Walking, getting in and out of chairs, bathing, dressing, toileting, and eating (scored as having no difficulty versus being able to do with difficulty or unable to do) and a scale of these items were regressed on patient characteristics. RESULTS: After adjustment for all characteristics, function limitations were found for those who smoked (effect sizes of significant associations range .04-.13), had chronic health conditions (.02-.33), were 85 years or older (.09-.46), needed assistance completing the survey (.32-1.29), were female (.05-.07), and had low income and assets (.15-.47). CONCLUSIONS: These nationally representative U.S. estimates of physical function characteristics are useful for interventions for vulnerable population subgroups.


Sujet(s)
Activités de la vie quotidienne , Régimes de rémunération à l'acte , Medicare (USA) , Autorapport , Humains , Femelle , Mâle , États-Unis/épidémiologie , Sujet âgé , Sujet âgé de 80 ans ou plus
10.
J Natl Cancer Inst Monogr ; 2024(65): 118-122, 2024 Aug 01.
Article de Anglais | MEDLINE | ID: mdl-39102882

RÉSUMÉ

The Surveillance, Epidemiology, and End Results (SEER) Program, an authoritative source of cancer statistics in the United States, has been funded by the National Cancer Institute (NCI) since 1973. The goals of SEER include measuring the cancer burden in the United States, making the results available, and supporting cancer research. These goals render products that serve as resources for different audiences, such as cancer registrars, researchers, and the public. Cancer registrars have access to a dedicated tab on the SEER website for questions, assistance with cancer coding, and training and technical resources such as SEER*Rx and SEER Data Management System (SEER*DMS). For researchers, SEER provides access to databases and software such as SEER*Stat and other linked databases such as SEER-Medicare that may offer answers to emerging issues in the field of cancer outcomes, cancer burden, health disparities, healthcare access, diagnosis, and prevention. The public can access cancer materials such as the SEER Cancer Stat Facts sheets, SEER*Explorer, and Did You Know? video series to learn more about cancer. SEER continues to update its resources with and ahead of legislation such as the Plain Writing Act and 21st Century Integrated Digital Experience Act (IDEA) to improve both clarity and user experience. Moving forward, SEER continues to promote awareness of SEER resources, remains accessible and understandable across all audiences, and standardizes how new resources are shared with these groups. The longstanding commitment to making cancer resources available is fundamental to the value of SEER, as evidenced by testimonials from members of various audience types.


Sujet(s)
Tumeurs , Programme SEER , Humains , Programme SEER/statistiques et données numériques , États-Unis/épidémiologie , Tumeurs/épidémiologie , Tumeurs/thérapie , National Cancer Institute (USA) , Medicare (USA) , Bases de données factuelles
11.
Health Aff (Millwood) ; 43(8): 1061-1066, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-39102600

RÉSUMÉ

With care coordination, problem solving, and an array of services, a model program helps dually eligible Medicare and Medicaid patients and their caregivers cope with dementia challenges.


Sujet(s)
Aidants , Démence , Medicaid (USA) , Medicare (USA) , Humains , Démence/thérapie , États-Unis , Aidants/psychologie , Sujet âgé , Femelle , Mâle , Détermination de l'admissibilité
12.
Health Aff (Millwood) ; 43(8): 1100-1108, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-39102602

RÉSUMÉ

The Centers for Medicare and Medicaid Services has placed growing emphasis on social drivers of health, but little is known about how accountable care organizations (ACOs) aim to meet the needs of vulnerable patients. During September-December 2022, we interviewed leaders of forty-nine ACOs participating in the Medicare Shared Savings Program (MSSP). Participants were asked about strategies to identify socially vulnerable patients, programs that addressed their needs, and Medicare reforms that could support their efforts. Seven themes emerged: ACOs were in the early stages of collecting social needs data; leaders were frustrated by an incomplete ability to act on such data; ACOs tended to stratify patients by medical, rather than social, risk; some ACOs have introduced pilot programs to address challenges, including social isolation and drug costs; programs were often payer agnostic; rural ACOs faced unique challenges; and Medicare reforms related to reimbursement, logistical support, quality metrics, and patient benefits could support ACO efforts. These findings suggest that the MSSP alone has not been sufficient to promote consistent investment in social needs provision at most ACOs. Policy makers may want to consider more direct support and incentives for health care organizations, or greater investment in non-health care sectors, to help socially vulnerable patients.


Sujet(s)
Accountable care organizations (USA) , Medicare (USA) , Populations vulnérables , Humains , États-Unis , Leadership , Mâle , Femelle , Entretiens comme sujet
13.
Health Aff (Millwood) ; 43(8): 1067-1072, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-39102608

RÉSUMÉ

For people dually eligible for Medicare and Medicaid, one integrated care plan option is coming to an end. States are planning what to offer next.


Sujet(s)
Prestation intégrée de soins de santé , Medicaid (USA) , Medicare (USA) , États-Unis , Humains , Détermination de l'admissibilité , Double éligibilité à Medicaid et Medicare
14.
BMC Health Serv Res ; 24(1): 916, 2024 Aug 10.
Article de Anglais | MEDLINE | ID: mdl-39123233

RÉSUMÉ

BACKGROUND: Many studies have described barriers to gender-affirming surgery (GAS) in Canada; however, few have explored why these barriers persist. To address this knowledge gap, we sought to describe documents related to public health insurance (Medicare) for GAS to identify the types of procedures covered, variations in coverage across provinces and territories, and changes in policy over time. METHODS: We conducted a descriptive cross-sectional study using an environmental scan approach. We queried 23 government websites, the Google search engine, and an online legal database between July 2022 and April 2024 to gather gray literature documents related to GAS and Medicare. Variables from relevant documents were compiled to create a present, at-glance overview of GAS Medicare coverage for all provinces and territories and a timeline of policy changes across Canada.  RESULTS: Eight provinces and three territories had documents or websites related to GAS Medicare coverage (85%). We identified 15 GAS procedures that were covered variably across Canada. Yukon (n = 14) covered the most types of GAS, while Quebec and Saskatchewan covered the least (n = 6). Mastectomy and genital surgeries were covered across Canada, but other GAS were rarely covered. Five provinces and territories provided coverage for travel-related costs. Our GAS Medicare timeline showed differential expansion of GAS coverage in Canada over the last 25 years. CONCLUSIONS : We provide previously unreported information regarding GAS Medicare coverage in Canada. We hope our findings will help patients and healthcare providers navigate a complicated public healthcare system. We also highlight barriers within GAS Medicare documents and make recommendations to alleviate those barriers.


Sujet(s)
Chirurgie de changement de sexe , Humains , Canada , Études transversales , Femelle , Chirurgie de changement de sexe/économie , Mâle , Politique de santé , Programmes nationaux de santé , Medicare (USA)/économie , Couverture d'assurance/statistiques et données numériques
15.
Am Fam Physician ; 110(2): online, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-39172668

RÉSUMÉ

Family medicine is financially undervalued compared with other medical specialties, and reimbursement fails to recognize the valuable longitudinal care provided to patients. According to one estimate, a primary care physician earns approximately $80,000 less than a subspecialist peer in Medicare reimbursement over a one-year period.1 This gap persists despite primary care physicians addressing higher numbers of medical concerns during office visits. To address continuity, the Centers for Medicare and Medicaid Services created the G2211 code in 2019 to compensate for the "visit complexity inherent to evaluation and management associated with medical care services."2 The G2211 code was implemented in January 2024.


Sujet(s)
Continuité des soins , Medicare (USA) , Soins de santé primaires , Humains , États-Unis , Soins de santé primaires/économie , Continuité des soins/économie , Medicare (USA)/économie , , Médecine de famille/économie
16.
PLoS One ; 19(8): e0309222, 2024.
Article de Anglais | MEDLINE | ID: mdl-39172922

RÉSUMÉ

PURPOSE: To study the effects of benign prostatic hyperplasia treatments, namely: alpha-adrenergic receptor blockers, 5-alpha-reductase inhibitors and phosphodiesterase-5 inhibitors on the risk of Parkinson's disease, Alzheimer's disease and mortality. MATERIALS AND METHODS: All male Medicare enrollees aged 65 or above who were diagnosed with benign prostatic hyperplasia and received one of the study drugs between 2007-2020 were followed-up for the three outcomes. We used Cox regression analysis to assess the relative risk of each of the outcomes for each study drug compared to the most prescribed drug, tamsulosin, while controlling for demographic, socioeconomic and comorbidity factors. RESULTS AND CONCLUSIONS: The study analyzed 1.1 million patients for a mean follow-up period of 3.1 years from being prescribed one of the study drugs. For all outcomes, patients on tamsulosin were used as the reference for comparison. For mortality, alfuzosin was associated with 27% risk reduction (HR 0.73, 95%CI 0.68-0.78), and doxazosin with 6% risk reduction (HR 0.94, 95%CI 0.91-0.97). For Parkinson's disease, terazosin was associated with 26% risk reduction (HR 0.74, 95%CI 0.66-0.83), and doxazosin with 21% risk reduction (HR 0.79, 95%CI 0.72-0.88). For Alzheimer's disease, terazosin was associated with 27% risk reduction (HR 0.73, 95%CI 0.65-0.82), and doxazosin with 16% risk reduction (HR 0.84, 95%CI 0.76-0.92). Tadalafil was associated with risk reduction (27-40%) in all 3 outcomes. More research is needed to elucidate the underlying mechanisms of these observations. Given the availability of safer alternatives for treating benign prostatic hyperplasia, caution should be exercised when using tamsulosin in elderly patients, especially those with an increased risk of developing neurodegenerative diseases.


Sujet(s)
Maladie d'Alzheimer , Medicare (USA) , Maladie de Parkinson , Hyperplasie de la prostate , Tamsulosine , Humains , Mâle , Tamsulosine/usage thérapeutique , Tamsulosine/effets indésirables , Sujet âgé , Hyperplasie de la prostate/traitement médicamenteux , Hyperplasie de la prostate/mortalité , Hyperplasie de la prostate/épidémiologie , Maladie d'Alzheimer/traitement médicamenteux , Maladie d'Alzheimer/mortalité , Maladie d'Alzheimer/épidémiologie , Medicare (USA)/statistiques et données numériques , États-Unis/épidémiologie , Maladie de Parkinson/traitement médicamenteux , Maladie de Parkinson/mortalité , Maladie de Parkinson/épidémiologie , Sujet âgé de 80 ans ou plus , Études de cohortes , Antagonistes des récepteurs alpha-1 adrénergiques/usage thérapeutique , Antagonistes des récepteurs alpha-1 adrénergiques/effets indésirables , Inhibiteurs de la 5-alpha réductase/usage thérapeutique , Inhibiteurs de la 5-alpha réductase/effets indésirables , Inhibiteurs de la phosphodiestérase-5/usage thérapeutique , Inhibiteurs de la phosphodiestérase-5/effets indésirables
17.
Emerg Infect Dis ; 30(9): 1926-1929, 2024 Sep.
Article de Anglais | MEDLINE | ID: mdl-39174032

RÉSUMÉ

We used Medicare data to identify >88,000 adults >65 years of age diagnosed and treated for Lyme disease during 2016-2019 in the United States. Most diagnoses occurred among residents of high-incidence states, in summer, and among men. Incidence of diagnoses was substantially higher than that reported through public health surveillance.


Sujet(s)
Maladie de Lyme , Humains , Maladie de Lyme/épidémiologie , Maladie de Lyme/diagnostic , États-Unis/épidémiologie , Sujet âgé , Mâle , Femelle , Sujet âgé de 80 ans ou plus , Incidence , Medicare (USA) , Histoire du 21ème siècle , Saisons
19.
JAMA Netw Open ; 7(8): e2428964, 2024 Aug 01.
Article de Anglais | MEDLINE | ID: mdl-39158909

RÉSUMÉ

Importance: Despite advances in treatment and care quality for patients hospitalized with heart failure (HF), minimal improvement in mortality has been observed after HF hospitalization since 2010. Objective: To evaluate trends in mortality rates across specific intervals after hospitalization. Design, Setting, and Participants: This cohort study evaluated a random sample of Medicare fee-for-service beneficiaries with incident HF hospitalization from January 1, 2008, to December 31, 2018. Data were analyzed from February 2023 to May 2024. Main Outcomes and Measures: Unadjusted mortality rates were calculated by dividing the number of all-cause deaths by the number of patients with incident HF hospitalization for the following periods: in-hospital, 30 days (0-30 days after hospital discharge), short term (31 days to 1 year after discharge), intermediate term (1-2 years after discharge), and long term (2-3 years after discharge). Each period was considered separately (ie, patients who died during one period were not counted in subsequent periods). Annual unadjusted and risk-adjusted mortality ratios were calculated (using logistic regression to account for differences in patient characteristics), defined as observed mortality divided by expected mortality based on 2008 rates. Results: A total of 1 256 041 patients (mean [SD] age, 83.0 [7.6] years; 56.0% female; 86.0% White) were hospitalized with incident HF. There was a substantial decrease in the mortality ratio for the in-hospital period (unadjusted ratio, 0.77; 95% CI, 0.67-0.77; risk-adjusted ratio, 0.74; 95% CI, 0.71-0.76). For subsequent periods, mortality ratios increased through 2013 and then decreased through 2018, resulting in no reductions in unadjusted postdischarge mortality during the full study period (30-day mortality ratio, 0.94; 95% CI, 0.82-1.06; short-term mortality ratio, 1.02; 95% CI, 0.87-1.17; intermediate-term mortality ratio, 0.99; 95% CI, 0.79-1.19; and long-term mortality ratio, 0.96; 95% CI, 0.76-1.16) and small reductions in risk-adjusted postdischarge mortality during the full study period (30-day mortality ratio, 0.88; 95% CI, 0.86-0.90; short-term mortality ratio, 0.94; 95% CI, 0.94-0.95; intermediate-term mortality ratio, 0.94; 95% CI, 0.92-0.95; and long-term mortality ratio, 0.95; 95% CI, 0.93-0.96). Conclusions and Relevance: In this study of Medicare fee-for-service beneficiaries, there was a substantial decrease in in-hospital mortality for patients hospitalized with incident HF from 2008 to 2018, but little to no reduction in mortality for subsequent periods up to 3 years after hospitalization. These results suggest opportunities to improve longitudinal outpatient care for patients with HF after hospital discharge.


Sujet(s)
Défaillance cardiaque , Hospitalisation , Medicare (USA) , Humains , Défaillance cardiaque/mortalité , Défaillance cardiaque/thérapie , États-Unis/épidémiologie , Femelle , Mâle , Medicare (USA)/statistiques et données numériques , Sujet âgé , Hospitalisation/statistiques et données numériques , Hospitalisation/tendances , Sujet âgé de 80 ans ou plus , Études de cohortes , Mortalité hospitalière/tendances
20.
Transl Vis Sci Technol ; 13(8): 34, 2024 Aug 01.
Article de Anglais | MEDLINE | ID: mdl-39172483

RÉSUMÉ

Purpose: Inflammatory and infectious eye diseases are an important cause of visual impairment in patients older than 65 years of age. Health care disparities for eye care are present for general eye care. However, there is lack of national data on health disparities regarding eye care use for inflammatory and infectious eye diseases. Our study examines the effect of gender and race on eye care in patients with inflammatory and infectious eye diseases who are equal or greater than 65 years of age. Methods: We have used Medicare data to examine the effect gender and race on use of eye care services in patients with inflammatory and infectious eye diseases for 2014 to 2018. Medicare is a national insurance program administered by the government of United States to insure people age 65 years or older. Owing to its high enrollment, those in Medicare are representative of the U.S. population aged 65 and older. Results: We found that females have higher use for Medicare for inflammatory and infectious eye diseases across all races from 2014 to 2018. On examining the effect of race, African Americans have lower use as compared with Whites. People of Asian descent have the highest use, followed by Hispanic people. Conclusions: Health care disparities exist for eye care use for inflammatory and infectious eye diseases for patients 65 years of age and older. Future studies are required to address these disparities to provide equitable eye care. Translational Relevance: Identification of eye care disparities is the first step to addressing these disparities.


Sujet(s)
Disparités d'accès aux soins , Medicare (USA) , Humains , États-Unis/épidémiologie , Medicare (USA)/statistiques et données numériques , Sujet âgé , Femelle , Mâle , Disparités d'accès aux soins/statistiques et données numériques , Disparités d'accès aux soins/ethnologie , Sujet âgé de 80 ans ou plus , Infections de l'oeil/thérapie , Maladies de l'oeil/ethnologie , Maladies de l'oeil/thérapie , Maladies de l'oeil/épidémiologie , Inflammation/épidémiologie
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