RÉSUMÉ
The seeds of Clitoria fairchildiana provided a new rotenoid, 6-hydroxy-2,3,9-trimethoxy-[1]benzopyrano[3,4-b][1]benzopyran-12(6H)-one. The structural elucidation was performed using detailed analyses of H- and 13C-NMR spectra including 2DNMR spectroscopic techniques (1H-13CHETCOR) and by comparison with spectrometric data from the literature. The anti-inflammatory activity was investigated using a capillary permeability assay.
Sujet(s)
Anti-inflammatoires/composition chimique , Clitoria/composition chimique , Roténone/analogues et dérivés , Graines/composition chimique , Animaux , Anti-inflammatoires/isolement et purification , Anti-inflammatoires/pharmacologie , Mâle , Souris , Souris de lignée BALB C , Modèles chimiques , Structure moléculaire , Roténone/composition chimique , Roténone/isolement et purification , Roténone/pharmacologieRÉSUMÉ
An attempt to clarify the taxonomy, the biogeography and the ethnobotany of the fishing poisons of Guiana and adjacent countries is presented. Collections have been made for every drug and field-notes concerning all ethnic groups of Guiana. Data are compared with published sources, particularly those of the past centuries. Ichthyotoxic plants have been classified into three groups: rotenone-yielding plants (Lonchocarpus, Derris, Tephrosia), saponin-yielding plants (Sapindaceae), and the "kunami" group of plants (Compositae, Euphorbiaceae). For each drug the vernacular names, the synonyms still used, the most notable morphological characteristics are specified, as well as ethnological observations and active constituents when known. Drugs and fishing-related techniques were selected long ago by Amerindians then often diffused through Amazonian countries by mixed-blood populations.