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1.
JMIR Ment Health ; 11: e49879, 2024 Jul 03.
Article de Anglais | MEDLINE | ID: mdl-38959061

RÉSUMÉ

BACKGROUND: Suicide is a leading cause of death worldwide. Journalistic reporting guidelines were created to curb the impact of unsafe reporting; however, how suicide is framed in news reports may differ by important characteristics such as the circumstances and the decedent's gender. OBJECTIVE: This study aimed to examine the degree to which news media reports of suicides are framed using stigmatized or glorified language and differences in such framing by gender and circumstance of suicide. METHODS: We analyzed 200 news articles regarding suicides and applied the validated Stigma of Suicide Scale to identify stigmatized and glorified language. We assessed linguistic similarity with 2 widely used metrics, cosine similarity and mutual information scores, using a machine learning-based large language model. RESULTS: News reports of male suicides were framed more similarly to stigmatizing (P<.001) and glorifying (P=.005) language than reports of female suicides. Considering the circumstances of suicide, mutual information scores indicated that differences in the use of stigmatizing or glorifying language by gender were most pronounced for articles attributing legal (0.155), relationship (0.268), or mental health problems (0.251) as the cause. CONCLUSIONS: Linguistic differences, by gender, in stigmatizing or glorifying language when reporting suicide may exacerbate suicide disparities.


Sujet(s)
Mass-médias , Stigmate social , Suicide , Humains , Femelle , Mâle , Suicide/psychologie , Suicide/statistiques et données numériques , Mass-médias/statistiques et données numériques , Facteurs sexuels , Adulte
4.
Int J Qual Stud Health Well-being ; 19(1): 2374751, 2024 Dec.
Article de Anglais | MEDLINE | ID: mdl-38954758

RÉSUMÉ

PURPOSE: The suicidal process contains both observable and non-observable phases, and patients have described the process as characterized by loneliness and darkness. Ambulance clinicians encounter patients in all phases of the suicidal process but little is known on what meaning this encounter has to the patients. The aim of this study was to elucidate meanings of encountering ambulance clinicians while being in a suicidal process. METHODS: Data were collected through fifteen individual interviews with eight participants who had lived experiences of encountering ambulance clinicians. Inductive design using phenomenological hermeneutical approach was used. FINDINGS: Patients are impacted by the clinicians, both in how they find their value in the situation, but also in expected trajectory. Three themes; 'Being impacted by representatives of society', 'Being unsure of one´s own value' and 'Regaining hope in moments of togetherness' generated the main theme ´Navigating oneself through the eyes of the other´. CONCLUSION: The way ambulance clinicians communicate impacts how patients navigate themselves in the ambivalence about living or dying, and the encounter either consolidate a feeling of being a burden, or instil hope of an endurable life. Through conversation, clinicians could support the patients in taking the first steps in the journey of recovery.


Sujet(s)
Ambulances , Humains , Femelle , Mâle , Adulte , Adulte d'âge moyen , Recherche qualitative , Solitude/psychologie , Espoir , Communication , Idéation suicidaire , Suicide/psychologie , Attitude du personnel soignant
5.
Sichuan Da Xue Xue Bao Yi Xue Ban ; 55(3): 739-743, 2024 May 20.
Article de Chinois | MEDLINE | ID: mdl-38948291

RÉSUMÉ

Objective: This study aims to investigate the agreement between the Huaxi Emotional Index (HEI) and the Nurses' Global Assessment of Suicide Risk (NGASR) in assessing high suicide risk and to explore the predictive value of HEI in identifying high suicide risk among patients with depression. Methods: Convenience sampling was used and 386 inpatients with depression were included in this cross-sectional study. All patients were admitted to the Mental Health Center, West China Hospital between June and December 2023. The inclusion criteria were as follows, a diagnosis of depression according to the International Classification of Diseases, Tenth Revision (ICD-10), age over 18, and completion of both NGASR and HEI assessments. According to the exclusion criteria, depression patients who had other comorbid mental disorders or those who had severe cognitive impairments and were unable to communicate effectively were excluded. The study was approved by the Biomedical Ethics Review Committee of West China Hospital (Approval No. 647, 2021). Demographic data such as age, sex, ethnicity, marital status, and educational attainment were collected using a self-designed questionnaire. Both the HEI and NGASR were applied to evaluate the patients. We conducted statistical analyses with SPSS 27, employing Spearman's rank correlation for correlation analysis, Kappa tests for consistency between the two instruments, and receiver operating characteristic (ROC) curves for evaluating the predictive performance of HEI scores for high suicide risk, with the optimal HEI cutoff value determined on the basis of the Youden Index. Results: The study included 386 depression inpatients with an average age of 32 years and an average length-of-stay of 14 days. Of these participants, 252 were female (65.3%) and 134 were male (34.7%). Regarding ethnicity, most of the participants were Han Chinese (89.4%), Tibetans accounted for 7.3%, and other minorities, 3.3%. Regarding marital status, 51.3% of the participants were married, 41.2% single, 6.5% divorced, and 1.0% widowed. Regarding educational attainment, 26.2% had an undergraduate or graduate education, 20.7% had junior college education, 24.8% had high school or secondary technical school education, and 28.2% had middle school education or less. The NGASR identified 57.3% of the participants as being at high suicide risk, while the HEI identified 53.6% as having severe emotional distress. There was a moderate agreement between the HEI and the NGASR scores, with a Kappa value of 0.518 ( P<0.001), indicating statistically significant differences. At an HEI score of 17, the Youden Index peaked at 0.52, predicting high suicide risk with a specificity of 76.36%, a sensitivity of 76.02%, and an area under the ROC curve of 0.829 (95% CI: 0.787-0.871), demonstrating statistically significant differences. Conclusion: HEI and NGASR demonstrate moderate agreement in assessing high suicide risk among depression patients. The HEI questionnaire effectively predicts high suicide risk in patients with depression, with 17 being the optimal cutoff value for assessing high suicide risk.


Sujet(s)
Dépression , Patients hospitalisés , Suicide , Humains , Femelle , Mâle , Dépression/diagnostic , Dépression/étiologie , Études transversales , Enquêtes et questionnaires , Suicide/psychologie , Suicide/statistiques et données numériques , Chine/épidémiologie , Appréciation des risques/méthodes , Émotions , Adulte , Facteurs de risque , Adulte d'âge moyen , Valeur prédictive des tests
6.
Ann Acad Med Singap ; 53(3): 152-169, 2024 Mar 27.
Article de Anglais | MEDLINE | ID: mdl-38920243

RÉSUMÉ

Introduction: This systematic review is aimed at (1) evaluating the association between media portrayals of suicides and subsequent copycat suicides or attempts among the general public in Asia, (2) understanding the factors associated with copycat suicides and (3) determining the positive impacts of the media reporting of suicides (e.g. increased help-seeking, coping). Method: A systematic review and narrative synthesis of English and Chinese articles from 8 electronic databases (i.e. PsycINFO, MEDLINE, Embase, CINAHL, Web of Science, Ariti, China National Knowledge Infrastructure and OpenGrey) from January 2000 to May 2023 was conducted. Observational studies were included, and the data were analysed through narrative synthesis. The protocol was registered with PROSPERO (CRD42021281535). Results: Among the 32 studies included (n=29 for evidence synthesis) in the review, there is good-quality evidence to show that copycat suicides and suicide attempts increase after media reports of a suicide, regardless of country, celebrity status, study design, type of media, mode of suicide or follow-up period. Females, younger age groups and those sharing similar characteristics as the deceased in publicised suicides (age, gender) were more susceptible to negative impact. Reporting of the mode of death of the deceased increased suicides by the same method among the public. Conclusion: Media portrayals of suicide appear to have a negative impact on copycat suicides at the population level in Asia. Thus, in addition to tighter media control, healthcare systems, professional medical bodies and community outreach services should work collaboratively to promote early help-seeking in those with psychological distress.


Sujet(s)
Mass-médias , Suicide , Humains , Suicide/statistiques et données numériques , Suicide/psychologie , Asie/épidémiologie , Tentative de suicide/statistiques et données numériques , Tentative de suicide/psychologie , Comportement de recherche d'aide , Comportement d'imitation , Adaptation psychologique , Facteurs sexuels , Facteurs âges , Femelle
7.
Obesity (Silver Spring) ; 32(7): 1235-1244, 2024 Jul.
Article de Anglais | MEDLINE | ID: mdl-38887179

RÉSUMÉ

Targeting the cannabinoid type 1 receptor (CB1) is a clinically validated antiobesity therapeutic approach. The only such drug approved, rimonabant, was launched in 2006 in Europe but subsequently rejected by the US Food and Drug Administration (FDA) in 2007. The FDA cited the increased risk of suicidality in its opposition to rimonabant's approval, leading to the drug's eventual worldwide withdrawal and the abandonment of this class of therapeutics. Seventeen years later, a new class of CB1-targeting drugs is emerging, but the impact of the 2007 FDA decision remains a formidable obstacle to its clinical development. We revisit the suicidality data presented by the FDA in light of the evolution of suicidality assessment and cross-reference this with the data in the subsequently published clinical trials. We conclude that the publicly available data do not support the FDA's conclusion that the use of rimonabant was associated with an increase in the risk of suicidality.


Sujet(s)
Agents antiobésité , Rimonabant , Suicide , Food and Drug Administration (USA) , Humains , États-Unis/épidémiologie , Agents antiobésité/effets indésirables , Suicide/statistiques et données numériques , Suicide/psychologie , Obésité/psychologie , Récepteur cannabinoïde de type CB1/antagonistes et inhibiteurs , Antagonistes des récepteurs de cannabinoïdes , Agrément de médicaments , Pyrazoles/usage thérapeutique , Pyrazoles/effets indésirables , Pipéridines/usage thérapeutique , Pipéridines/effets indésirables
8.
Med Sci Monit ; 30: e944838, 2024 Jun 20.
Article de Anglais | MEDLINE | ID: mdl-38900715

RÉSUMÉ

In a reality dominated by social media and affected by the recent COVID-19 pandemic, the mental health of people in various age groups has undoubtedly suffered, especially among young people. Statistics confirm that adolescent depression is a significant health problem and is the most common cause of disability in this age group. Research shows the multifactorial basis of this disease entity, placing particular emphasis on the genetic, environmental, and biological background. A family history of depression can increase the risk of developing depression by 4-fold. A teenager, being part of many systems, such as family, school community, and social media co-user, is exposed to many stressors. Maturing youth have a very demanding educational plan to implement, and depression causes a decline in cognitive functions, which are so important in acquiring knowledge. Among many patients, an additional risk is self-harm and suicide, which are part of the clinical picture of depressive disorders. Suicide accounts for about one-third of mortality among youth. We draw attention to the need to increase educational and psychoeducational impacts on adolescent depression, as it is a huge health problem that has an impact on all areas of a young person's life. The trend of depression among adolescents is constantly increasing. The aim of this article is to review the global causes and consequences of the growing number of cases of depression, self-harm, and suicide among children and adolescents, as well as contemporary approaches to management.


Sujet(s)
COVID-19 , Dépression , Pandémies , Médias sociaux , Adolescent , Humains , COVID-19/épidémiologie , COVID-19/psychologie , Dépression/épidémiologie , Trouble dépressif/épidémiologie , Santé mentale , SARS-CoV-2 , Comportement auto-agressif/épidémiologie , Comportement auto-agressif/psychologie , Suicide/psychologie , Enfant
9.
Article de Anglais | MEDLINE | ID: mdl-38929047

RÉSUMÉ

The suicide rates in Guyana, Suriname and Trinidad and Tobago are among the highest in the Americas, containing significant Indo-Caribbean populations that are suggested to be most vulnerable to suicide. This systematic review analyzes the existing literature and identifies knowledge gaps in risk and protective factors against suicide in these countries. The literature search conducted followed PRISMA guidelines using the PubMed and APA PsycInfo databases. The PRISMA flow diagram illustrated that eight scholarly papers were eligible for inclusion. Included literature examined stratified data focused on the aforementioned countries, as well as their Indo-Caribbean adolescent populations. Excluded literature did not mention suicidality, adolescents, Indo-Caribbeans, or the focal countries or was focused on the Jonestown mass murder-suicide event. The studies encompassed 6581 individuals. Identified risk factors include social stigma regarding suicide, mental health resource scarcity, and difficult socioeconomic conditions. The identified protective factors for youth include religious/spiritual practices and group activities. Limitations include database quantity, risk of publication bias, and the small sample for each study. A prevailing social stigma regarding suicide was identified. Greater research is needed relating to effects of suicide legislation, bereavement experiences, sociocultural contexts, geography, migration patterns, and culturally compatible interventions to aid future suicide prevention efforts. The protocol was registered with PROSPERO (CRD42023417494).


Sujet(s)
Suicide , Humains , Adolescent , Suicide/statistiques et données numériques , Suicide/psychologie , Facteurs de risque , Idéation suicidaire
10.
Soc Cogn Affect Neurosci ; 19(1)2024 Jul 02.
Article de Anglais | MEDLINE | ID: mdl-38874947

RÉSUMÉ

Aggression and impulsivity are linked to suicidal behaviors, but their relationship to the suicidal crisis remains unclear. This magnetoencephalography (MEG) study investigated the link between aggression, impulsivity, and resting-state MEG power and connectivity. Four risk groups were enrolled: high-risk (HR; n = 14), who had a recent suicidal crisis; lower-risk (LR; n = 41), who had a history of suicide attempts but no suicide attempt or ideation in the past year; clinical control (CC; n = 38), who had anxiety/mood disorders but no suicidal history; and minimal risk (MR; n = 28), who had no psychiatric/suicidal history. No difference in resting-state MEG power was observed between the groups. Individuals in the HR group with high self-reported aggression and impulsivity scores had reduced MEG power in regions responsible for sensory/emotion regulation vs. those in the HR group with low scores. The HR group also showed downregulated bidirectional glutamatergic feedback between the precuneus (PRE) and insula (INS) compared to the LR, CC, and MR groups. High self-reported impulsivity was linked to reduced PRE to INS feedback, whereas high risk-taking impulsivity was linked to upregulated INS to postcentral gyrus (PCG) and PCG to INS feedback. These preliminary findings suggest that glutamatergic-mediated sensory and emotion-regulation processes may function as potential suicide risk markers.


Sujet(s)
Agressivité , Comportement impulsif , Magnétoencéphalographie , Humains , Comportement impulsif/physiologie , Mâle , Magnétoencéphalographie/méthodes , Femelle , Agressivité/physiologie , Agressivité/psychologie , Adulte , Jeune adulte , Suicide/psychologie , Idéation suicidaire , Tentative de suicide/psychologie , Cortex somatosensoriel/physiologie , Adolescent
11.
Rev Med Liege ; 79(5-6): 319-325, 2024 Jun.
Article de Français | MEDLINE | ID: mdl-38869118

RÉSUMÉ

Suicide is a public health problem that affects people throughout their lives: from childhood to adolescence, and from adulthood to old age. Numerous risk factors for suicide have been identified, not only at the level of the individual, but also at the level of the family, the community and society as a whole. These factors include the existence of a mental health problem, in particular depression and substance abuse. At the clinical level, it is important to try to spot the signs of impending suicide and organize an appropriate care strategy. But there are also protective factors against suicide at individual, societal and cultural levels. There are many strategies for preventing suicide. These approaches range from raising awareness of the problem of suicide among the general population and destigmatizing mental illnesses, to more targeted measures for people at risk of suicide: actively treating depression, training healthcare professionals to identify individuals at risk, developing telephone helplines, setting up peer-help programs and developing post-hospitalisation follow-up programs.


Le suicide est un problème de santé publique qui touche les personnes tout au long de leur vie : de l'enfance à l'adolescence, et de l'âge adulte aux personnes âgées. De nombreux facteurs de risque de suicide ont été identifiés non seulement au niveau de l'individu, mais également au niveau de la famille, de la communauté et de la société. Parmi ceux-ci, citons l'existence d'une pathologie mentale, en particulier la dépression et les abus de substances. Au niveau clinique, il importe d'essayer de repérer les signes de suicide imminent et de mettre en place une stratégie adéquate. Mais il existe également des facteurs de protection contre le suicide au niveau individuel, sociétal, ou culturel. Nombreuses sont les stratégies de prévention du suicide. Cela va de la sensibilisation de la population générale à la problématique du suicide et la déstigmatisation des pathologies mentales, à des mesures plus ciblées pour le public à risque de suicide : traiter activement la dépression, former les professionnels de la santé à identifier les individus à risque, développer des lignes téléphoniques d'urgence, mettre en place des programmes de «pair-aidance¼ et développer des programmes de suivi post-hospitalisation.


Sujet(s)
Prévention du suicide , Humains , Facteurs de risque , Suicide/psychologie
12.
Front Public Health ; 12: 1378481, 2024.
Article de Anglais | MEDLINE | ID: mdl-38873323

RÉSUMÉ

Introduction: Suicide is a significant public health problem, impacting individuals, families and communities worldwide. Effective suicide prevention requires a comprehensive approach with diverse integrated interventions and collaboration across sectors, stakeholders and professions. This study aims to identify challenges, gaps and success factors in current suicide prevention efforts in Germany, Austria and Switzerland, providing specific recommendations for advancement. Methods: We conducted online, semi-structured interviews with 36 suicide prevention experts from Germany, Austria and Switzerland, incorporating perspectives from policy, science and practice. Interviews were conducted between September 2022 and February 2023, audio-recorded, transcribed verbatim and analyzed using the Framework method. Results: Despite progress in national strategies and coordinated efforts for suicide prevention, challenges such as resource scarcity, stigma and structural issues in psychiatric and psychotherapeutic care persist. The interviewees identified several areas for advancement, including developing targeted prevention measures for men and older people, strengthening collaboration across sectors, stakeholders and professions, and increasing the involvement of individuals with lived experience. While the COVID-19 pandemic has exacerbated challenges in psychiatric and psychotherapeutic care, it has concurrently strengthened interest in suicide prevention among policymakers and the media. Discussion: National suicide prevention strategies play a crucial role in setting priorities, raising public awareness, and guiding action. However, since most suicide prevention efforts are still predominantly health sector-driven, a more comprehensive approach is needed to promote the involvement of all relevant actors and address suicidality as a collective societal responsibility. Tailoring prevention programs for risk groups like older people and men is important, as these populations show high suicide rates and face a lack of targeted interventions. Our study underscores the importance to continuously monitor, refine and strengthen collaborative and evidence-based suicide prevention efforts.


Sujet(s)
COVID-19 , Recherche qualitative , Prévention du suicide , Humains , Autriche , Suisse , Allemagne , Mâle , Femelle , COVID-19/prévention et contrôle , COVID-19/épidémiologie , Adulte , Entretiens comme sujet , Adulte d'âge moyen , Suicide/statistiques et données numériques , Suicide/psychologie
13.
BMC Psychiatry ; 24(1): 444, 2024 Jun 14.
Article de Anglais | MEDLINE | ID: mdl-38877487

RÉSUMÉ

BACKGROUND: Suicide prevention media campaigns are one way of reaching people at increased suicide risk who would otherwise not seek help. This is the first study of a Norwegian campaign directed both at individuals at risk for suicide and at their social network. METHODS: We evaluated a media campaign consisting of outdoor posters, feature articles, film clips, and online banners in print, digital, and social media spread across the Mid-Norway region in late autumn 2022. This campaign material consisted of information about how to seek help for suicide thoughts and mental health problems and how to help a friend in similar situations. Before and after this campaign, 1149 adult individuals living in Mid-Norway participated in a survey on attitudes to suicide, mental ill health, and help-seeking. RESULTS: There were only marginal changes in attitudes and help-seeking literacy after the campaign. This result was sustained when controlling for age, sex, and campaign visibility. For males, there were a few changes in the negative direction, i.e. lack of willingness to seek help from family and friends, after the campaign. CONCLUSION: We conclude that the campaign did not seem to have the desired effect and suggest ways of improving future regional Norwegian media campaigns.


Sujet(s)
Mass-médias , Prévention du suicide , Humains , Mâle , Norvège , Femelle , Adulte , Adulte d'âge moyen , Jeune adulte , Comportement de recherche d'aide , Promotion de la santé/méthodes , Connaissances, attitudes et pratiques en santé , Adolescent , Médias sociaux , Sujet âgé , Acceptation des soins par les patients/psychologie , Suicide/psychologie , Enquêtes et questionnaires
14.
Cell Rep Med ; 5(6): 101613, 2024 Jun 18.
Article de Anglais | MEDLINE | ID: mdl-38897169

RÉSUMÉ

The gender paradox in suicide research refers to the phenomenon that while males report higher suicide mortality, females suffer more from suicidal thoughts, leading to higher suicidal risks. This paradox may lead to the misconception that female suicides do not require as much attention. Therefore, there is an urgent need for researchers to shift their perspectives from the current male-centric approach to more inclusive knowledge for female suicidality. Following this, the current commentary emphasizes the importance of identifying and addressing the crucial but overlooked psychosocial factors underlying female suicidality. In addition, the ecological framework is employed as a guiding tool for exploring the intricate interplay of biological, psychological, societal, and cultural factors that are associated with female suicidality, thereby allowing researchers and stakeholders to develop more effective prevention and intervention strategies tailored to women's needs. Overall, this commentary calls for more refined and equitable approaches to suicide prevention that address the needs of individuals for all gender identities.


Sujet(s)
Prévention du suicide , Suicide , Humains , Femelle , Suicide/psychologie , Mâle , Idéation suicidaire , Facteurs sexuels , Facteurs de risque
15.
PeerJ ; 12: e17468, 2024.
Article de Anglais | MEDLINE | ID: mdl-38827287

RÉSUMÉ

The aim of this study was to evaluate the effectiveness of ChatGPT-3.5 and ChatGPT-4 in incorporating critical risk factors, namely history of depression and access to weapons, into suicide risk assessments. Both models assessed suicide risk using scenarios that featured individuals with and without a history of depression and access to weapons. The models estimated the likelihood of suicidal thoughts, suicide attempts, serious suicide attempts, and suicide-related mortality on a Likert scale. A multivariate three-way ANOVA analysis with Bonferroni post hoc tests was conducted to examine the impact of the forementioned independent factors (history of depression and access to weapons) on these outcome variables. Both models identified history of depression as a significant suicide risk factor. ChatGPT-4 demonstrated a more nuanced understanding of the relationship between depression, access to weapons, and suicide risk. In contrast, ChatGPT-3.5 displayed limited insight into this complex relationship. ChatGPT-4 consistently assigned higher severity ratings to suicide-related variables than did ChatGPT-3.5. The study highlights the potential of these two models, particularly ChatGPT-4, to enhance suicide risk assessment by considering complex risk factors.


Sujet(s)
Dépression , Suicide , Humains , Appréciation des risques , Mâle , Femelle , Adulte , Suicide/psychologie , Dépression/psychologie , Dépression/épidémiologie , Facteurs de risque , Idéation suicidaire , Armes , Adulte d'âge moyen , Jeune adulte , Tentative de suicide/psychologie , Tentative de suicide/statistiques et données numériques , Prévention du suicide
16.
Neurology ; 103(1): e209397, 2024 Jul 09.
Article de Anglais | MEDLINE | ID: mdl-38833656

RÉSUMÉ

BACKGROUND AND OBJECTIVES: Individuals with epilepsy have increased risk of suicidal ideation (SI) and behaviors when compared with the general population. This relationship has remained largely unexplored in adolescents. We investigated the prevalence of suicidality in adolescents with newly diagnosed focal epilepsy within 4 months of treatment initiation and over the following 36 months. METHODS: This was a post hoc analysis of the enrollment and follow-up data from the Human Epilepsy Project, an international, multi-institutional study that enrolled participants between 2012 and 2017. Participants enrolled were 11-17 years of age within 4 months of treatment initiation for focal epilepsy. We used data from the Columbia Suicide Severity Rating Scale (C-SSRS), administered at enrollment and over the 36-month follow-up period, along with data from medical records. RESULTS: A total of 66 adolescent participants were enrolled and completed the C-SSRS. At enrollment, 14 (21%) had any lifetime SI and 5 (8%) had any lifetime suicidal behaviors (SBs). Over the following 36 months, 6 adolescents reported new onset SI and 5 adolescents reported new onset SB. Thus, the lifetime prevalence of SI within this population increased from 21% to 30% (14-20 adolescents), and the lifetime prevalence of SB increased from 8% to 15% (5-10). DISCUSSION: The prevalence of suicidality in adolescents with newly diagnosed focal epilepsy reported in our study is consistent with previous findings of significant suicidality observed in epilepsy. We identify adolescents as an at-risk population at the time of epilepsy diagnosis and in the following years.


Sujet(s)
Épilepsies partielles , Idéation suicidaire , Humains , Adolescent , Mâle , Femelle , Épilepsies partielles/épidémiologie , Épilepsies partielles/psychologie , Épilepsies partielles/diagnostic , Prévalence , Enfant , Études de suivi , Suicide/statistiques et données numériques , Suicide/psychologie
18.
Int J Mol Sci ; 25(11)2024 May 25.
Article de Anglais | MEDLINE | ID: mdl-38891940

RÉSUMÉ

Suicide is a major public health priority, and its molecular mechanisms appear to be related to glial abnormalities and specific transcriptional changes. This study aimed to identify and synthesize evidence of the relationship between glial dysfunction and suicidal behavior to understand the neurobiology of suicide. As of 26 January 2024, 46 articles that met the inclusion criteria were identified by searching PubMed and ISI Web of Science. Most postmortem studies, including 30 brain regions, have determined no density or number of total Nissl-glial cell changes in suicidal patients with major psychiatric disorders. There were 17 astrocytic, 14 microglial, and 9 oligodendroglial studies using specific markers of each glial cell and further on their specific gene expression. Those studies suggest that astrocytic and oligodendroglial cells lost but activated microglia in suicides with affective disorder, bipolar disorders, major depression disorders, or schizophrenia in comparison with non-suicided patients and non-psychiatric controls. Although the data from previous studies remain complex and cannot fully explain the effects of glial cell dysfunction related to suicidal behaviors, they provide risk directions potentially leading to suicide prevention.


Sujet(s)
Marqueurs biologiques , Encéphale , Névroglie , Suicide , Humains , Névroglie/métabolisme , Névroglie/anatomopathologie , Suicide/psychologie , Encéphale/métabolisme , Encéphale/anatomopathologie , Autopsie , Idéation suicidaire , Trouble bipolaire/métabolisme , Trouble bipolaire/anatomopathologie
19.
BMC Public Health ; 24(1): 1571, 2024 Jun 11.
Article de Anglais | MEDLINE | ID: mdl-38862974

RÉSUMÉ

BACKGROUND: Rates of self-harm and suicide are rising for young people globally and many implicate social media in this problem. To address this concern and to increase the confidence of adults to communicate safely about suicide and social media with young people, the #chatsafe Guide for Parents and Carers was developed in Australia. With significant uptake of the resource among Australian adults, the aim of the current study was to update and contextualise the #chatsafe Guide for Parents and Carers for audiences in 15 countries globally. To improve the relevance of this resource for parents and carers in these countries, the present study sought to understand the concerns held by parents, carers and suicide prevention professionals around the world about these topics and to explore the extent to which a resource such as #chatsafe would be helpful within their communities. METHODS: Seven focus groups were conducted via Zoom with parents, carers and suicide prevention professionals (n = 40) from 15 countries. Transcribed data were coded and thematically analysed using both inductive and deductive processes. RESULTS: Six themes are reported: (1) Two scary 'S' words; (2) Country and culture impact who talks (or is silent) about self-harm and suicide; (3) The need for a protective social ecosystem; (4) #chatsafe is a tool that can help parents, carers and young people worldwide; (5) #chatsafe should consider local context and end users to improve its relevance for parents and carers worldwide; and (6) A range of marketing and dissemination strategies are needed to reach adults with #chatsafe information. Findings of this study informed the update and contextualisation of the #chatsafe Guide for Parents and Carers for adult audiences in 15 countries. CONCLUSIONS: The findings from this study underscore a universal need for psychoeducation initiatives that provide adults with the skills and knowledge to support the mental health of young people, both online and offline, and that resources like #chastafe can play an important role in providing reliable information about these topics to adults across a range of cultures and contexts.


Sujet(s)
Aidants , Groupes de discussion , Parents , Recherche qualitative , Médias sociaux , Humains , Parents/psychologie , Aidants/psychologie , Aidants/statistiques et données numériques , Adulte , Mâle , Femelle , Australie , Médias sociaux/statistiques et données numériques , Comportement auto-agressif/prévention et contrôle , Prévention du suicide , Adulte d'âge moyen , Adolescent , Jeune adulte , Soutien social , Suicide/psychologie , Suicide/statistiques et données numériques
20.
Psychiatry Res ; 338: 115978, 2024 Aug.
Article de Anglais | MEDLINE | ID: mdl-38823163

RÉSUMÉ

This study examined trajectories of suicide-risk and their relationship to symptoms, recovery, and quality of life over time. Data was obtained from the Recovery after an Initial Schizophrenia Episode Early Treatment Program (RAISE-ETP) study. 404 individuals with first-episode psychosis (FEP) completed measures of suicide-risk, depression, positive symptoms, recovery, and quality of life at baseline, 6mo, 12mo, 18mo, and 24mo. Latent class analysis was used to identify temporal trajectories of suicide-risk. General linear mixed models for repeated measures were used to examine the relationship between the latent trajectories of suicide-risk and clinical variables. Results identified three latent trajectories of suicide-risk (low-risk, worsening, and improving). The low-risk and improving classes experienced improvements in depression, positive symptoms, quality of life, and recovery over time. The worsening class experienced improvements in positive symptoms and quality of life, but no change in depression or recovery. These results suggest that some individuals with FEP are at risk for persistent depression and worsening suicide-risk during treatment despite experiencing improvements in positive symptoms and quality of life. These findings have important clinical implications, as persistent depression and worsening suicide-risk might be masked by the primary focus on positive symptoms and quality of life in most FEP clinics.


Sujet(s)
Dépression , Troubles psychotiques , Qualité de vie , Humains , Troubles psychotiques/psychologie , Femelle , Mâle , Adulte , Jeune adulte , Dépression/psychologie , Adolescent , Suicide/psychologie , Suicide/statistiques et données numériques , Schizophrénie
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