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J Neurovirol ; 23(6): 932-934, 2017 12.
Article de Anglais | MEDLINE | ID: mdl-29147884

RÉSUMÉ

Zika virus (ZIKV) is an emerging flavivirus which has been linked to a number of neurologic manifestations such as Guillain-Barré syndrome (GBS), transverse myelitis, and meningo-encephalitis. Ophthalmologic manifestations are increasingly being reported; however, ocular dyskinesias have not been described in this context to date. Herein, we report a case of a 22-year-old female who presented with ocular flutter and associated Guillain-Barré syndrome following acute ZIKV infection. We speculate that although such symptoms may have originated from a direct viral insult, a post-infectious autoimmune mechanism may not be excluded. Physicians should include ZIKV as well as other flaviviruses in their diagnostic workup for all patients with ocular flutter/opsoclonus, after excluding other non-infectious causes of central nervous system pathology. To the best of our knowledge, this is the first report on the association of ocular flutter, GBS, and ZIKV infection.


Sujet(s)
Ataxie/diagnostic , Syndrome de Guillain-Barré/diagnostic , Troubles de la motilité oculaire/diagnostic , Infection par le virus Zika/diagnostic , Aciclovir/usage thérapeutique , Anticorps antiviraux/sang , Antiviraux/usage thérapeutique , Ataxie/traitement médicamenteux , Ataxie/physiopathologie , Ataxie/virologie , Femelle , Syndrome de Guillain-Barré/traitement médicamenteux , Syndrome de Guillain-Barré/physiopathologie , Syndrome de Guillain-Barré/virologie , Humains , Immunoglobulines par voie veineuse/usage thérapeutique , Troubles de la motilité oculaire/traitement médicamenteux , Troubles de la motilité oculaire/physiopathologie , Troubles de la motilité oculaire/virologie , Jeune adulte , Virus Zika/immunologie , Infection par le virus Zika/traitement médicamenteux , Infection par le virus Zika/physiopathologie , Infection par le virus Zika/virologie
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