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1.
Voen Med Zh ; 338(2): 18-24, 2017 02.
Article in Russian | MEDLINE | ID: mdl-30593090

ABSTRACT

Comparative evaluation of effectivennes and safety of the local hemostatic agents in the experiment. On the model side damage the femoral artery of pigs we performed a comperative test of modern local hemostatic agents (LHA): bandages on the basis of chitosan <> (TG), eGemofleks Combat> (GC), (GB) bandages on kaolin-based <> (CG), and the usual bandage 10 cm x 3 m (control group). 25 animals were divided equally into 5 groups. After 45 seconds of bleeding from 6-mm side wound of femoral artery was used LHA with a three-minute external compression and wound edges approximation. In the case of the continuation-bleeding wounds performed re-tamponade with the second package of the LHA. Hemostasis after applying the first packet never recorded in the CG group, occurred in I out of 5 animals in the groups TG and GC, 2 of 5 animals in the group GB and the control group (p>0,05). Application of two packages LHA in the TG group, GB and the control group was effective in 3 of 5 animals and in groups CG and GC - in 2 of 5 animals (p>0,05). Mortality did not differ significantly between the groups. Thus, the conventional bandage wound with ordinary tamponade in this model is not less effective than current LHA.


Subject(s)
Bandages , Femoral Artery/injuries , Hemorrhage/therapy , Hemostatics/therapeutic use , Animals , Drug Evaluation, Preclinical , Female , Hemostatics/adverse effects , Humans , Male , Swine
2.
Khirurgiia (Mosk) ; (11): 37-41, 2005.
Article in Russian | MEDLINE | ID: mdl-16352992

ABSTRACT

The experience with 233 stomach resections in "difficult" ulcers is analyzed. The main cause of complications and lethality after these surgeries is duodenal stump sutures insufficiency seen in 17 (7.3%) patients, and in 10 (4.3%) patients it was the cause of death. Original duodenal stump cover was performed in 86 patients. There were no cases of suture insufficiency, two patients died of pneumonia and hepatic failure.


Subject(s)
Duodenum/surgery , Gastrectomy/methods , Postoperative Complications/epidemiology , Stomach Ulcer/surgery , Aged , Female , Humans , Liver Diseases/etiology , Liver Diseases/mortality , Male , Middle Aged , Pneumonia/etiology , Pneumonia/mortality , Postoperative Hemorrhage/mortality , Survival Rate
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