1.
Mol Divers
; 25(2): 1123-1130, 2021 May.
Article
in English
| MEDLINE
| ID: mdl-32076910
ABSTRACT
Some 5-substituted 3-aminopyrazoles were used for the synthesis of isoindolo[2,1-c]pyrazolo[1,5-a]quinazoline and pyrazolo[5',1':2,3]pyrimido[6,1-a]isoindol derivatives via a mild and efficient one-pot three-component reaction with 2-formylbenzoic acid and different CH-acids under solvent-free condition.
Subject(s)
Isoindoles/chemical synthesis , Pyrazoles/chemical synthesis , Quinazolines/chemical synthesis , Catalysis , Green Chemistry Technology , Pyrazoles/chemistry
2.
Mol Divers
; 24(3): 753-761, 2020 Aug.
Article
in English
| MEDLINE
| ID: mdl-31321647
ABSTRACT
A novel one-pot four-component reaction of an aldehyde, malononitrile, hydrazine and 4,4-dimethyl-3-oxopentanenitrile is described. As regio- and chemoselective products, 7-amino-2-(tert-butyl)-5-aryl-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carbonitriles are formed during the course of the reaction.