Organophosphate esters and their metabolites in silver pomfret (Pampus argenteus) of the Vietnamese coastal areas: Spatial-temporal distribution and exposure risk.

A large number of studies on organophosphate esters (tri-OPEs) in marine organisms have not assessed the simultaneous occurrence of tri-OPEs and their metabolites (di-OPEs) in these species. This research investigated the concentration and geographical distribution of 15 tri-OPEs and 7 di-OPEs in 172 samples of Pampus argenteus that were collected annually from 2021 to 2023 at three distinct locations along the Vietnamese coast. As a result, tri-OPEs and di-OPEs were detected in numerous fish samples, indicating their widespread spatial and temporal occurrence in marine fish and pointing out the importance of monitoring their levels. The tri-OPEs and di-OPEs ranged within 2.1-38.9 ng g-1 dry weight (dw) and 3.2-263.4 ng g-1 dw, respectively. The mean concentrations of tri-OPEs ranged from 0.4 (TIPrP) to 5.4 ng g-1 dw (TBOEP), with TBOEP and TEHP having the highest mean values. In addition, the profiles of tri-OPEs in fish exhibited a descending order: Σalkyl OPEs > ΣCl-alkyl OPEs > Σaryl OPEs. The di-OPEs, namely BEHP and DMP, had the highest mean levels, measuring 33.4 ng g-1 dw and 23.8 ng g-1 dw, respectively. Furthermore, there have been significant findings of strong positive correlations between di-OPEs and tri-OPE pairs (p < 0.05). It is worth noting that there is a noticeable difference in the composition of tri-OPEs between the North and other regions. Despite these findings, the presence of OPE-contaminated fish did not pose any health risks to Vietnam's coastal population.

A Comprehensive Evaluation of Dioxins and Furans Occurrence in River Sediments from a Secondary Steel Recycling Craft Village in Northern Vietnam.

This first study investigated the presence of dioxins and furans in river sediments around a craft village in Vietnam, focusing on Secondary Steel Recycling. Sediment samples were collected from various locations along the riverbed near the Da Hoi Secondary Steel Recycling village in Bac Ninh province. The analysis was conducted using a HRGC/HRMS-DFS device, detecting a total of 17 dioxin/furan isomers in all samples, with an average total concentration of 288.86 ng/kg d.w. The concentrations of dioxin/furan congeners showed minimal variation among sediment samples, ranging from 253.9 to 344.2 ng/kg d.w. The predominant compounds in the dioxin group were OCDD, while in the furan group, they were 1,2,3,4,6,7,8-HpCDF and OCDF. The chlorine content in the molecule appeared to be closely related to the concentration of dioxins and their percentage distribution. However, the levels of furan isomers did not vary significantly. The distribution of these compounds was not dependent on the flow direction, as they were mainly found in solid waste and are not water-soluble. Although the hepta and octa congeners had high concentrations, when converted to TEQ values, the tetra and penta groups (for dioxins) and the penta and hexa groups (for furans) contributed more to toxicity. Furthermore, the source of dioxins in sediments at Da Hoi does not only originate from steel recycling production activities but also from other combustion sites. The average total toxicity was 10.92 ng TEQ/kg d.w, ranging from 4.99 to 17.88 ng TEQ/kg d.w, which did not exceed the threshold specified in QCVN 43:2017/BTNMT, the National Technical Regulation on Sediment Quality. Nonetheless, these levels are still concerning. The presence of these toxic substances not only impacts aquatic organisms in the sampled water environment but also poses potential health risks to residents living nearby.

Quantification of parabens in marine fish samples by a rapid, simple, effective sample preparation method.

Parabens (p-hydroxybenzoic acid esters) commonly used preservatives (in cosmetics, pharmaceuticals, and foods) can pose potential effects on environmental health. In this study, seven parabens were quantified in marine fish samples using an ultra-high performance liquid chromatography triple quadrupole mass spectrometer (UHPLC-MS/MS) system. Parabens in the fish samples were extracted and purified by a rapid, simple, and effective procedure comprising sample homogenization with solvent, solid-phase extraction clean-up, and solvent evaporation. Results demonstrated that the recoveries of seven compounds (with relative standard deviation < 15%) were 88-103% in matrix-spike samples and 86-105% in surrogate standards. The method detection limits and method quantification limits of seven parabens were 0.015-0.030 and 0.045-0.090 ng/g-ww (wet weight), respectively. The optimized method was applied to measure the concentration of parabens in the 37 marine fish samples collected from Vietnam coastal waters. The concentration ranges of seven parabens found in round scad and greater lizardfish samples were 6.82-25.3 ng/g ww and 6.21-17.2 ng/g-ww, respectively. Among parabens, methylparaben accounted for the highest contribution in both fish species (43.2 and 44.9%, respectively). Based on the measured concentrations of parabens in marine fish samples, the estimated daily intake was calculated for children and adults with the corresponding values of 0.0477 µg/kg/day and 0.0119 µg/kg/day, respectively. However, the presence of parabens in Vietnamese marine fish may not pose a significant risk to human health.

Occurrence, distribution, and risk assessment of halogenated organic pollutants (HOPs) in marine fish muscle: The case study of Vietnam.

Halogenated organic pollutants (HOPs), including polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), and chlorophenols (CPs), were identified in three marine fish species in Vietnam. Total PCBs, OCPs, and CPs concentrations ranged from 4.5 to 711.6 ng g-1 lipid weight (lw), 69.9-2360 ng g-1 lw, and 208.1-3941.2 ng g-1 lw, respectively. CPs were the most frequently detected pollutants in the marine environment of Vietnam of the three HOPs studied, followed by OCPs and PCBs. There are significant differences in HOPs between three types of seafood in Vietnam, including yellowstripe scad, Indian mackerel, and silver pomfret in this study. Notably, the types and amounts of HOPs found in the fish were differently influenced by the economic and industrial activities of the sampled areas. Despite these findings, the consumption of HOP-contaminated fish from the study areas was found not to pose any significant health risks to Vietnam's coastal population.

Occurrence and risk of human exposure to organophosphate flame retardants in indoor air and dust in Hanoi, Vietnam.

The presence and distribution of thirteen organophosphate flame retardants (OPFRs) were investigated in indoor air and dust samples collected in Hanoi, Vietnam. The total OPFRs (Æ©OPFRs) concentrations in indoor air and dust samples were 42.3-358 ng m-3 (median 101 ng m-3) and 1290-17,500 ng g-1 (median 7580 ng g-1), respectively. The profile of OPFRs in both indoor air and dust indicated that tris(1-chloro-2-propyl) phosphate (TCIPP) was the most dominant compound with a median concentration of 75.3 ng m-3 and 3620 ng g-1, contributing 75.2% and 46.1% to Æ©OPFRs concentrations in indoor air and dust, respectively, followed by tris(2-butoxyethyl) phosphate (TBOEP), with a median concentration of 16.3 ng m-3 and 2500 ng g-1, contributing 14.1% and 33.6% to Æ©OPFRs concentrations in indoor air and dust, respectively. The levels of OPFRs in the indoor air samples and corresponding indoor dust samples showed a strong positive correlation. The total estimated daily intakes (EDItotal) of Æ©OPFRs (via air inhalation, dust ingestion, and dermal absorption) for adults and toddlers under the median and high exposure scenarios were 36.7 and 160 ng kg-1 d-1, and 266 and 1270 ng kg-1 d-1, respectively. Among the investigated exposure pathways, dermal absorption was a primary exposure pathway to OPFRs for both toddlers and adults. The hazard quotients (HQ) ranged from 5.31 × 10-8 to 6.47 × 10-2 (<1), and the lifetime cancer risks (LCR) were from 2.05 × 10-11 to 7.37 × 10-8 (<10-6), indicating that human health risks from exposure to OPFRs in indoor environments are not significant.

Heavy metals in cultured oysters (Saccostrea glomerata) and clams (Meretrix lyrata) from the northern coastal area of Vietnam.

Oysters and clams are abundant and popularly consumed seafood in Viet Nam. These bivalves were proved to be suitable bioindicators to assess the heavy metal accumulation in the aquatic environment. The study is to investigate heavy metals such as As, Cd, Hg and Pb in the cultured oysters Saccostrea glomerata and clams Meretrix lyrata collected in VanDon - Quang Ninh, and CatBa - Hai Phong. The results showed that the metal heavy concentrations in the oysters Saccostrea glomerata and clams Meretrix lyrata presented in the order of As > Cd > Pb > Hg. The most polluted concentration with As among four heavy metals studied in six sampling sites was 2.81 ± 1.07 and 1.6 ± 0.62 mg/kg wet weight for clams and oysters, respectively. Investigated heavy metals in cultured oysters and clams indicated potential risks for human health in future by assessment of the heavy metals.

Ischemic Colitis Presented as Pseudomembranous Colitis: An Untypical Case from Vietnam.

Ischemic colitis (IC) is an underreported chronic disease characterized by the hypoperfusion of the bowel mucosa. The diagnosis and treatment may be challenging because its clinical course resembles other colitis or even colorectal malignancies. This paper reports an untypical case to underline the diversity of IC manifestation. A 68-year-old man with several comorbidities was admitted because of abdominal pain with a 6-month duration and a mass in the left lower quadrant. Colonoscopy revealed erosive pseudomembranous colitis narrowed colon segments with ulcerated mucosa mimicking colorectal cancer and inflammatory bowel disease. The stool cultures and Clostridium difficile toxin tests were negative. After the failure of conservative therapy, the Hartmann procedure with temporary ileostomy was performed uneventfully. The histological results of the surgical specimens revealed IC with focal pseudomembranous areas.

Geographical origin traceability of Sengcu rice using elemental markers and multivariate analysis.

Multi-element analysis combined with chemometric method has been used to investigate the distinguish between Sengcu rice and other types of rice origins in Vietnam. In Sengcu rice, As, Ba Sr, Pb, Ca, Se were confirmed as the key elements for geographical traceability among three fields of Lao Cai, whereas Al, Ca, Fe, Mg, Ag, As were major factors to distinguish between Sengcu and other types of rice. Based on linear discriminant analysis and partial least squares-discriminant analysis model, overall correct identification rates distinguishing between Sengcu and other types of rice were approximately 100% in both training and validation test. Moreover, to distinguish geographical origin of Sengcu rice samples, these rates vary from 80% to 99%. These results suggest the presence of food adulteration illustrated in the latter.

A survey of parabens in aquatic environments in Hanoi, Vietnam and its implications for human exposure and ecological risk.

Seven parabens including methylparaben (MeP), ethylparaben (EtP), propylparaben (PrP), iso-propylparaben (iPrP), butylparaben (BuP), benzylparaben (BzP), and heptylparaben (HepP) were determined in bottled water, tap water, river water, lake water, and wastewater samples collected from Hanoi, Vietnam, using solid phase extraction (SPE) followed by ultrahigh performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The highest total concentration of parabens were measured in wastewater (range, 27.3-1050 ng/L; mean/median, 268/175 ng/L), followed by lake water (range, 18.0-254 ng/L; mean/median, 51.7/58.5 ng/L), river water (range, 16.5-52.1 ng/L; mean/median, 32.1/42.6 ng/L), tap water (range, 5.01-54.3 ng/L; mean/median, 28.6/41.1 ng/L), and bottled water (range, 1.56-39.9 ng/L; mean/median, 6.92/9.19 ng/L). Methylparaben and propylparaben were the predominant compounds found in all samples. The mean estimated human exposure dose of parabens through drinking bottled water was 0.27 ng/kg-bw/day, which is 6 orders of magnitude below the safety threshold recommended by the Joint FAO/WHO Expert Committee on Food Additive in 1974 (10 mg/kg-bw/day). Concentrations of parabens measured in river water, lake water, and wastewater samples were assessed to pose low to moderate ecological risks to aquatic organisms (0.1 < RQ < 1). Methyl, ethyl, and propyl parabens exhibited significant correlations in water samples.

A Combination of Chromatography with Tandem Mass Spectrometry Systems (UPLC-MS/MS and GC-MS/MS), Modified QuEChERS Extraction and Mixed-Mode SPE Clean-Up Method for the Analysis of 656 Pesticide Residues in Rice.

The emerging ungovernable application of pesticides in rice farming has attracted public concerns as these hazardous chemicals leave long-lasting environmental impacts and cause severe health effects. Here, an optimized analytical method was proposed for the measurement of 656 pesticide residues in rice samples collected in Vietnam. We utilized chromatography with tandem mass spectrometry systems (UPLC-MS/MS and GC-MS/MS) combined with a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction method and adopted a mixed-mode SPE clean-up method for the analysis. The results showed that a total of 341 and 315 compounds were determined by UPLC- and GC-MS/MS, respectively. Usage of 10 mL MeCN, 5 mL H2O and 1% glacial acetic acid as extraction solvent outperformed other mixtures in purifying the analytes from the sample matrix. Besides, pressure swing adsorption connected to a C18 cartridge with C18 placed on top exhibited remarkably more extracted compounds of high recovery which resulted in 299 and 318 compounds with recovery ranging from 70 to 120% in GC- and UPLC-MS/MS, respectively. Our optimized protocols also resulted in maximal limits of quantification of 10 µg Kg-1 in both MS methods with repeatability and reproducibility less than 20%. Application of validated method on 20 rice samples collected in Hanoi, Vietnam showed that 14 samples were contaminated with at least one pesticide, and insecticide was the most detected group. Overall, the compliance of all method validation parameters to SANTE/12682/2019 Guideline demonstrates that this protocol can be employed for the effective management of Vietnam's rice in accordance with international requirements.

Desalination and removal of pesticides from surface water in Mekong Delta by coupling electrodialysis and nanofiltration.

The shortage of drinking water is a major problem in the rural areas of the Mekong Delta, especially, when surface water, a main local direct drinking water source is being threatened by pesticide pollution and salinity intrusion. A hybrid process coupling electrodialysis (ED) and nanofiltration (NF) is proposed as an effective process easy to setup in a small plant to treat complex matrix with high salinity and pesticide concentration as is the Mekong Delta surface water. Performance of the ED-NF integration was evaluated with synthetic solutions based on the comparison with a single NF step generally used for pesticide removal. Both energy consumption and water product quality were considered to assess process efficiency. The ED stage was designed to ensure a 50% removal of salinity before applying NF. As expected, the NF rejection is better in the hybrid process than in a case of a single NF step, especially for pesticide rejection. The integration of a NF stage operated with NF270 membrane consumes less energy than that with NF90 membrane but its efficiency was observed not high enough to respect the Vietnamese guidelines. Using NF90, the optimal recovery rate of the NF stage varies from 30 to 50% depending on the salt content in the feed.