ABSTRACT
A short cut review was conducted to assess if the use of rocuronium in the ED was associated with a decrease in the provision of postintubation sedation. Four papers were identified that presented the best evidence to answer the question. Again the studies, relevant outcomes, results and weaknesses are tabulated. All the identified studies were retrospective and there was a plethora of outcome measures used. When compared with suxamethonium, rocuronium was associated with a delayed initiation and reduced dose of postintubation sedation.
Subject(s)
Hypnotics and Sedatives/administration & dosage , Neuromuscular Blocking Agents/administration & dosage , Rapid Sequence Induction and Intubation/standards , Time Factors , Dose-Response Relationship, Drug , Humans , Hypnotics and Sedatives/therapeutic use , Intubation, Intratracheal/methods , Neuromuscular Blocking Agents/therapeutic use , Rapid Sequence Induction and Intubation/methods , Retrospective Studies , Rocuronium/administration & dosage , Rocuronium/therapeutic use , Succinylcholine/adverse effects , Succinylcholine/therapeutic useABSTRACT
A short cut review of the literature was carried out to establish whether any risk factors would predict the need for endotracheal intubation in undifferentiated adult patients presenting with poisoning/overdose with unknown substance. Five papers presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. It is concluded that further robust studies of large cohorts are needed to answer this difficult question.
