The effects of Facebook and Instagram on the 2020 election: A deactivation experiment.

We study the effect of Facebook and Instagram access on political beliefs, attitudes, and behavior by randomizing a subset of 19,857 Facebook users and 15,585 Instagram users to deactivate their accounts for 6 wk before the 2020 U.S. election. We report four key findings. First, both Facebook and Instagram deactivation reduced an index of political participation (driven mainly by reduced participation online). Second, Facebook deactivation had no significant effect on an index of knowledge, but secondary analyses suggest that it reduced knowledge of general news while possibly also decreasing belief in misinformation circulating online. Third, Facebook deactivation may have reduced self-reported net votes for Trump, though this effect does not meet our preregistered significance threshold. Finally, the effects of both Facebook and Instagram deactivation on affective and issue polarization, perceived legitimacy of the election, candidate favorability, and voter turnout were all precisely estimated and close to zero.

Interventions to Mitigate Financial Toxicity in Adult Patients with Cancer in the United States: A Scoping Review.

Financial toxicity adversely affects quality of life and treatment outcomes for patients with cancer. This scoping review examined interventions aimed at mitigating financial toxicity in adult patients with cancer and their effectiveness. We utilized five bibliographical databases to identify studies that met our inclusion criteria. The review included studies conducted among adult patients with cancer in the United States and published in English between January 2011 to March 2023. The review identified eight studies that met the inclusion criteria. Each of the studies discussed the implementation of interventions at the patient/provider and/or health system level. Collectively, the findings from this scoping review highlight both the limited number of published studies that are aimed at mitigating financial toxicity and the need to create and assess interventions that directly impact financial toxicity in demographically diverse populations of adult patients with cancer.

Temporal fenestration in a Procolophon trigoniceps specimen (Procolophonoidea) from the Lower Triassic of Brazil.

The parareptiles diversified widely during the Permian and persisted in Pangean ecosystems until the end of the Triassic. However, most parareptiles succumbed to the Permian-Triassic extinction, leading to the exclusive survival of procolophonoids. Procolophonoidea stands out as one of the most diverse parareptile clades, with about 40 species across Pangean land masses. The Early Triassic species Procolophon trigoniceps is known from South Africa, Antarctica, and Brazil. The majority of cranial materials of this procolophonoid are described as anapsid in temporal morphology, however, some skulls discovered in South Africa were found to exhibit temporal fenestration. Once thought to have systematic significance for the genus Procolophon, temporal fenestration was lately proposed to be an anomalous or pathological feature in P. trigoniceps. In this study, we describe new cranial material of P. trigoniceps from the Sanga do Cabral Formation of Brazil that clearly displays temporal fenestration. Aside from the fenestra, the specimen closely resembles more complete Brazilian P. trigoniceps skulls. The recurrent presence of the feature and the varying morphologies exhibited by the temporal fenestrae of P. trigoniceps may substantiate its characterization as an anomalous trait within the species. Furthermore, the occurrence of temporal fenestration in P. trigoniceps specimens from both South America and South Africa underscores parallels between these two Early Triassic ecosystems.

Images dataset of beef meat samples with different shelf life.

Three different cuts of meat samples: inside skirt, knuckles, and sirloin were picture captioned on the first and fifth day after purchase. From each type of meat cut, ten pictures were taken at the beginning and the end of the studied shelf life, obtaining 60 different images. The images were taken under control variables in a black acrylic cabin. In addition to the original images, we proportionate another set of 60 processed images. The latter were obtained after color calibration and meat segmentation. All these images could be used for future experiments where the color in meat should be analyzed.

Papiloma humano según la percepción de estudiantes universitarios / Human papilloma according to the perception of university students

El objetivo del presente estudio fue determinar el conocimiento sobre el Virus del Papiloma Humano (VPH) en estudiantes universitarios de la ciudad de Guayaquil, Se realizó una investigación con alcance descriptivo y transaccional, con una población constituida por 3000 estudiantes universitarios, y una muestra probabilística de 332. La técnica empleada fué la encuesta y el instrumento de recolección de la información, un cuestionario con 15 preguntas. El conocimiento de esta enfermedad se determinó mediante una escala de valoración en las siguientes categorías: Insuficiente: de 1-3; Regular: 4-6; Bueno: 7-9; Muy Bueno; 10-12 y Excelente: 13-15. Se realizó la prueba de Kolmogorov- Smirnov para determinar la normalidad de la distribución de datos y la prueba del Chi-cuadrado para la comprobación de las hipótesis planteadas, los datos se procesaron con el paquete estadístico SPSS 21,0. Se concluye que existe una asociación significativa entre el grado de conocimiento del papiloma humano con la edad y el sexo de los estudiantes universitarios(AU)

The objective of the present study was to determine the knowledge about the Human Papilloma Virus (HPV) in university students in the city of Guayaquil. An investigation with a descriptive and cross-sectional scope was carried out, with a population made up of 3000 university students, and a probabilistic sample of 332. The technique used was the survey and the data collection instrument, a questionnaire with 15 questions. Knowledge of this disease was determined using an assessment scale in the following categories: Insufficient: 1-3; Regular: 4-6; Good: 7-9; Very good; 10-12 and Excellent: 13-15. The Kolmogorov-Smirnov test was performed to determine the normality of the data distribution and the Chi-square test to verify the hypotheses proposed, the data was processed with the SPSS 25.0 statistical package. It is concluded that there is a significant association between the degree of knowledge of the human papilloma with the age and sex of university students(AU)

Digging deeper into colonial palaeontological practices in modern day Mexico and Brazil.

Scientific practices stemming from colonialism, whereby middle- and low-income countries supply data for high-income countries and the contributions of local expertise are devalued, are still prevalent today in the field of palaeontology. In response to these unjust practices, countries such as Mexico and Brazil adopted protective laws and regulations during the twentieth century to preserve their palaeontological heritage. However, scientific colonialism is still reflected in many publications describing fossil specimens recovered from these countries. Here, we present examples of 'palaeontological colonialism' from publications on Jurassic-Cretaceous fossils from NE Mexico and NE Brazil spanning the last three decades. Common issues that we identified in these publications are the absence of both fieldwork and export permit declarations and the lack of local experts among authorships. In Mexico, access to many fossil specimens is restricted on account of these specimens being housed in private collections, whereas a high number of studies on Brazilian fossils are based on specimens illegally reposited in foreign collections, particularly in Germany and Japan. Finally, we outline and discuss the wider academic and social impacts of these research practices, and propose exhaustive recommendations to scientists, journals, museums, research institutions and government and funding agencies in order to overcome these practices.

Platelets modulate CD4+ T-cell function in COVID-19 through a PD-L1 dependent mechanism.

Severe COVID-19 is associated with a systemic inflammatory response and progressive CD4+ T-cell lymphopenia and dysfunction. We evaluated whether platelets might contribute to CD4+ T-cell dysfunction in COVID-19. We observed a high frequency of CD4+ T cell-platelet aggregates in COVID-19 inpatients that inversely correlated with lymphocyte counts. Platelets from COVID-19 inpatients but not from healthy donors (HD) inhibited the upregulation of CD25 expression and tumour necrosis factor (TNF)-α production by CD4+ T cells. In addition, interferon (IFN)-γ production was increased by platelets from HD but not from COVID-19 inpatients. A high expression of PD-L1 was found in platelets from COVID-19 patients to be inversely correlated with IFN-γ production by activated CD4+ T cells cocultured with platelets. We also found that a PD-L1-blocking antibody significantly restored platelets' ability to stimulate IFN-γ production by CD4+ T cells. Our study suggests that platelets might contribute to disease progression in COVID-19 not only by promoting thrombotic and inflammatory events, but also by affecting CD4+ T cells functionality.

Associations between occupation, leprosy disability and other sociodemographic factors in an endemic area of Brazil.

BACKGROUND: In Brazil, new leprosy cases with grade-2 disability (G2D) have been increasing. Physical disability has been associated with experienced stigmatization, psychological distress, and social restriction. OBJECTIVES: To identify factors associated with leprosy disability in an endemic area of Brazil focusing on occupational and other sociodemographic factors. METHODS: Between July and December 2015, adult patients with multibacillary leprosy who attended a clinic in Belo Horizonte, Brazil were enrolled. Social, clinical, and demographic factors were collected from an administered questionnaire and medical charts. Occupations were categorized as manual vs non-manual. Descriptive statistics and multivariable logistic regression were performed to study associated factors with disability (Grade 1 disability (G1D) and G2D combined). FINDINGS: Seventy-three patients were enrolled with 48 (65.8%) presenting with either G1D or G2D at the time of enrollment. Twenty-nine (39.7%) had G2D. About half of the patients (n = 36, 49%) reported a manual labor occupation and reactions were common (n = 53, 73%). On univariate analyses, older age (p = 0.048) and low education (p = 0.007) were associated with disability. On multivariable analyses, only low education (primary or less) was associated with disability (OR = 6.34, 95% CI 1.37, 29.26). Greater distance from clinic, income, smoking, marital status, and occupation were not associated. MAIN CONCLUSIONS: Low education was associated with leprosy disability, consistent with prior studies, and therefore should be a focus for disability reduction programs. While the sample size of this study may have limited detection of associations between disability and social determinants tested, half of the patients reported a manual job, highlighting the need for more extensive studies on associations between occupation, disability, and related injuries.

Técnica de All-on-4 como opción terapéutica en la rehabilitación mandibular completa: complicaciones técnicas, biológicas e índice de satisfacción de los pacientes / All-on-4 technique as a therapeutic option in the complete mandibular rehabilitation: technical and biological complications and patient satisfaction index

Introducción: Las rehabilitaciones completas se han visto limitadas por los accidentes anatómicos de los maxilares, por lo que diversas técnicas han surgido durante los años para la colocación de los implantes necesarios. Entre ellas, el concepto de All-On-4 permite la rehabilitación de una arcada completa con cuatro implantes, que serán colocados cerca de estructuras anatómicas en pacientes con reabsorciones óseas severas, evitando así cirugías adicionales. Materiales y métodos: El tipo de estudio fue un estudio observacional descriptivo, retrospectivo y transversal en el que se seleccionaron un total de 12 pacientes: 6 pacientes rehabilitados mediante el protocolo de All-on-four (Grupo 1) y 6 pacientes rehabilitados con una prótesis híbrida sobre seis implantes (Grupo 2). Se analizó: Tipo de tratamiento; Nivel de inflamación gingival; Pérdida ósea marginal; Nivel de satisfacción; Complicaciones biológicas y mecánicas; Sexo; Edad. Resultados: En las variables más importantes, se observó que el índice de sangrado fue ligeramente mayor para el Grupo 1. La pérdida ósea marginal fue mayor para el grupo 2. Los pacientes se sentían a gusto con ambos tratamientos, pero el valor es más alto para el Grupo 1. Conclusiones: El índice de satisfacción global analizado resulta alto en ambos grupos y permite valorar de forma muy positiva las dos planificaciones de tratamiento. No hay relación entre las variables sexo, edad o tipo de tratamiento y el nivel de satisfacción. No se puede determinar una relación entre el tipo de tratamiento y el índice de sangrado o pérdida ósea marginal. (AU)

Introduction: Full-arch rehabilitations are limited by the anatomical structures of the maxillas, so different techniques have been proposed for the placement of implants. The All-On-4 concept allows for full-arch rehabilitation with four implants, which will be placed near anatomical structures in patients with severe bone resorption, avoiding additional surgeries. Material and methods: The study design is an observational, descriptive, retrospective and transversal study, which gathered 12 patients: 6 patients treated with the All-On-4 protocol (Group 1) and 6 patients with a hybrid prostheses supported by 6 implants (Group 2). The variables analyzed were: Treatment type; Bleeding on probing; Marginal bone loss; Grade of satisfaction; Biological complications and mechanical complications; Gender; Age. Results: The most important variables showed that Bleeding on probing was slightly higher for Group 1. Marginal bone loss was higher for Group 2. Patients were all satisfied with both treatment options, but the results were higher for Group 1. Conclusions: The global satisfaction index is high in both groups, which rates both treatment options as very positive. There is no relation between gender, age or treatment option and the level of satisfaction. A correlation cannot be made between the treatment option and marginal bone loss or bleeding on probing. (AU)

Design and analysis of a mechanical ventilation system based on cams.

Low-cost mechanical ventilators have been developed in order to deal with the shortage of traditional ventilators whose quantity is not sufficient in an emergency context in Perú. Protofy, a company from Spain, designed one of the first low-cost mechanical ventilation systems OxyGEN which was approved by a medicine agency in its country in special context of COVID 19. Therefore, as main of this article, a redesign of this system named OxygenIP.PE was carried out according to local requirements and available technology, but maintaining its working concept based on compression mechanism by cams. Sensors were added and a control algorithm of the respiratory rate was developed. Ventilation curves monitoring over time was implemented; in this sense, a mathematical model of the whole system was developed. OxygenIP.PE was redesigned, fabricated, and tested measuring its ventilation curves over time. Results indicate that this redesign provides a sturdy equipment able to work during a longer lifetime than the original. The replicability of the ventilation curves behavior is ensured, while the mechanism dimensions are adapted for a particular airbag resuscitator. The mathematical model of the whole system can satisfactorily determine the ventilation curves over time and is used to show the air pressure, volume, and flow as a function of the compression arm's angular position and differential pressure through the breathing circuit measurement, furthermore the algorithms designed as a consequence of the mathematical model were implemented for Raspberry and ARDUINO microcontrollers. There were obtained parameters of pressure 10-65 cmH2O, airflow 50-65 l/m, volume 0-0.5 l, at two values of beat per minute (BPM) 15 and 25.

Hydroxychloroquine / azithromycin in COVID-19: The association between time to treatment and case fatality rate.

BACKGROUND: Currently, there is no formally accepted pharmacological treatment for COVID-19. MATERIALS AND METHODS: We included COVID-19 outpatients of a Peruvian primary care center from Lima, Peru, who were treated between April 30 - September 30, 2020, with hydroxychloroquine and azithromycin. Logistic regression was applied to determine factors associated with case-fatality rate. RESULTS: A total of 1265 COVID-19 patients with an average age of 44.5 years were studied. Women represented 50.1% of patients, with an overall 5.9 symptom days, SpO2 97%, temperature of 37.3 °C, 41% with at least one comorbidity and 96.1% one symptom or sign. No patient treated within the first 72 h of illness died. The factors associated with higher case fatality rate were age (OR = 1.06; 95% CI 1.01-1.11, p = 0.021), SpO2 (OR = 0.87; 95% CI 0.79-0.96, p = 0.005) and treatment onset (OR = 1.16; 95% CI 1.06-1.27, p = 0.002), being the latter the only associated in the multivariate analysis (OR = 1.18; 95% CI 1.05-1.32, p = 0.005). 0.6% of our patients died. CONCLUSIONS: The case fatality rate in COVID-19 outpatients treated with hydroxychloroquine/azithromycin was associated with the number of days of illness on which treatment was started.

Análisis multivariado HJ-Biplot de la ocurrencia de Helicobacter pylori como riesgo para cáncer gástrico, en la ciudadela el Cristo de Consuelo, Milagro Ecuador / HJ-Biplot multivariate analysis of the occurrence of Helicobacter pylori as a risk for gastric cancer, in the citadel of El Cristo de Consuelo, Milagro Ecuador

El Helicobacter pylori, es el causante del mayor número de úlceras y cáncer gástrico a nivel mundial. Población de 15 a 20 años, de escasos recursos y con mayor precariedad en el funcionamiento de los servicios públicos como es el agua potable son altamente vulnerables. Por lo que se planteó como objetivo, realizar un análisis multivariado HJ-Biplot de la ocurrencia de H. pylori como riesgo para cáncer gástrico, en la ciudadela el Cristo de Consuelo, Milagro Ecuador. Estudio epidemiológico transversal, descriptiva y de tipo observacional, contó con una población finita de 230 personas. Técnicas de recolección de datos: la encuesta, la observación directa y la detección de H. pylori en las muestras de heces. El análisis de las muestras biológicas se realizó mediante el método de Elisa en muestras de suero y heces. A los datos obtenidos se les aplicó el método de análisis multivariado bidireccional llamado HJ-Biplot, reflejándose en las variables las relaciones de las composiciones químicas, físicas y biológicas. Los resultados conforman dos grupos de puntos de muestra que coinciden satisfactoriamente con las estaciones de la región. Con este estudio se demuestra que los métodos estadísticos multivariantes son valiosos para interpretar conjuntos de datos complejos, concretamente, para la red de prevalencia de cáncer gástrico causado por el bacilo H. pylori, ha ido en aumento en los últimos años tanto en el Ecuador como en el resto del mundo. Es necesario que se establezcan los mecanismos de control de los agentes causantes de la propagación de este bacilo lo que incidirá en la disminución en la tasa de crecimiento del cáncer gástrico(AU)

Helicobacter pylori is the cause of the highest number of ulcers and gastric cancer worldwide. Population aged 15 to 20 years, with limited resources and with greater precariousness in the operation of public services such as drinking water, are highly vulnerable. Therefore, the objective was to carry out a multivariate HJ-Biplot analysis of the occurrence of H. pylori as a risk for gastric cancer, in the citadel of Cristo de Consuelo, Milagro Ecuador. Cross-sectional, descriptive and observational epidemiological study, had a finite population of 230 people. Data collection techniques: survey, direct observation and detection of H. pylori in stool samples. Analysis of biological samples was performed using the Elisa method in samples of serum and feces. The obtained data were applied the method of bi-directional multivariate analysis called HJ-Biplot, reflecting in the variables the relationships of the chemical, physical and biological compositions. The results form two groups of sample points that successfully coincide with the stations in the region. This study shows that multivariate statistical methods are valuable for interpreting complex data sets, specifically for the prevalence network of gastric cancer caused by the H. pylori bacillus, which has been increasing in recent years both in Ecuador and in the rest of the world. it is necessary to establish the control mechanisms of the agents that cause the spread of this bacillus, which will affect the decrease in the growth rate of gastric cáncer(AU)

Resistencia a insecticidas en Aedes aegypti y Aedes albopictus (Diptera: Culicidae) de Tapachula, Chiapas, México / Insecticide resistance in Aedes aegypti and Ae. albopictus (Diptera: Culicidae) populations from Tapachula, Chiapas, Mexico

Resumen: Objetivo: Determinar la resistencia a insecticidas en Ae. aegypti y Ae. albopictus de Tapachula, Chiapas, México. Material y métodos: Se utilizaron ovitrampas para obtener huevos de mosquitos Aedes y se realizaron pruebas de susceptibilidad (CDC) y ensayos enzimáticos con la primera generación. Resultados: Aedes aegypti mostró resistencia a deltametrina, permetrina, malatión, clorpirifos, temefos y a bendiocarb (CARB), mientras que Aedes albopictus a malatión y en menor grado a cloripirifos, temefos, permetrina y deltametrina. Ambas especies mostraron altos niveles de enzimas como citocomo P450 y glutatión S-tranferasa, mientras que los niveles de esterasas variaron por especie y sitio muestreado. Se detectó acetilcolinesterasa insensible a insecticidas en ambas especies. Conclusión: En un hábitat urbano de Tapachula, Chiapas, México donde se aplica control con insecticidas Ae. aegypti y Ae. albopictus sólo son susceptibles al propoxur.

Abstract: Objective: To determine the insecticide resistance status of Ae. aegypti and Ae. albopictus from Tapachula, México. Materials and methods: Mosquito eggs were collected with the use of ovitraps and CDC susceptibility bioassays and biochemical assays were conducted to determine resistance levels and resistance mechanisms, respectively. Results: Ae. aegypti showed resistance to deltamethrin and permethrin (PYRs), malathion, chlorpyrifos and temephos (OP), and to bendiocarb (CARB), while Ae. albopictus showed resistance to malathion and to a lesser intensity to chlorypirifos, temephos, permethrin and deltamethrin. Both species showed high levels of P450 and GSTs, while levels of esterases varied by species and collection site. Altered acethilcholinesterase was detected in both species. Conclusion: In an urban habitat from Tapachula, Chiapas, Mexico where vector control using insecticides takes place, Ae. aegypti and Ae. albopictus are only susceptible to propoxur.

[Insecticide resistance in Aedes aegypti and Ae. albopictus (Diptera: Culicidae) populations from Tapachula, Chiapas, Mexico]. / Resistencia a insecticidas en Aedes aegypti y Aedes albopictus (Diptera: Culicidae) de Tapachula, Chiapas, México.

OBJECTIVE: To determine the insecticide resistance status of Ae. aegypti and Ae. albopictus from Tapachula, México. MATERIALS AND METHODS: Mosquito eggs were collected with the use of ovitraps and CDC susceptibility bioassays and biochemical assays were conducted to determine resistance levels and resistance mechanisms, respectively. RESULTS: Ae. aegypti showed resistance to deltamethrin and permethrin (PYRs), malathion, chlorpyrifos and temephos (OP), and to bendiocarb (CARB), while Ae. albopictus showed resistance to malathion and to a lesser intensity to chlorypirifos, temephos, permethrin and deltamethrin. Both species showed high levels of P450 and GSTs, while levels of esterases varied by species and collection site. Altered acethilcholinesterase was detected in both species. CONCLUSIONS: In an urban habitat from Tapachula, Chiapas, Mexico where vector control using insecticides takes place, Ae. aegypti and Ae. albopictus are only susceptible to propoxur.

OBJETIVO: Determinar la resistencia a insecticidas en Ae. aegypti y Ae. albopictus de Tapachula, Chiapas, México. MATERIAL Y MÉTODOS: Se utilizaron ovitrampas para obtener huevos de mosquitos Aedes y se realizaron pruebas de susceptibilidad (CDC) y ensayos enzimáticos con la primera generación. RESULTADOS: Aedes aegypti mostró resistencia a deltametrina, permetrina, malatión, clorpirifos, temefos y a bendiocarb (CARB), mientras que Aedes albopictus a malatión y en menor grado a cloripirifos, temefos, permetrina y deltametrina. Ambas especies mostraron altos niveles de enzimas como citocomo P450 y glutatión S-tranferasa, mientras que los niveles de esterasas variaron por especie y sitio muestreado. Se detectó acetilcolinesterasa insensible a insecticidas en ambas especies. CONCLUSIONES: En un hábitat urbano de Tapachula, Chiapas, México donde se aplica control con insecticidas Ae. aegypti y Ae. albopictus sólo son susceptibles al propoxur.

Captorhinid reptiles from the lower Permian Pedra de Fogo Formation, Piauí, Brazil: the earliest herbivorous tetrapods in Gondwana.

The Pedra de Fogo Formation in the Parnaíba Basin of northeastern Brazil hosts a recently discovered lacustrine fauna and provides the only known record of the Captorhinidae in South America. Here, new captorhinid remains from this unit are described. Two partial mandibles, including one formerly ascribed to the genus Captorhinus, are here referred to Captorhinikos sp. a genus previously described from North America. The natural mould of a large mandible probably represents a new taxon within the captorhinid subclade Moradisaurinae, and a small skull roof is regarded as Captorhinidae indet. Captorhinids are generally considered to have been herbivores or omnivores. The Pedra de Fogo captorhinids likely played an important ecological role as primary consumers in the palaeoenvironment of this geological unit, which is also known for its extensive record of petrified forests. The new finds reinforce the close relationships between the continental faunas of palaeotropical western Gondwana and palaeoequatorial North America during the Cisuralian.

Neumonía grave en la comunidad: ¿cuándo pensar en SAMR-AC? / Severe community pneumonia: when to think about CA-MRSA

ntroducción: Aunque la incidencia de neumonía adquirida en la comunidad (NAC) por Staphylococcus aureus meticilino-resistente adquirido en la comunidad (SAMR-AC) es inferior al 10%, por su elevada mortalidad debe considerarse en los pacientes graves.Objetivo: Identificar factores de riesgo asociados con SAMR-AC en pacientes con NAC grave. Material y métodos: Estudio observacional, retrospectivo, que analizó pacientes con NAC con diagnóstico etiológico ingresados en terapia intensiva en un hospital público entre 2006 y 2017.Resultados: Se incluyeron 250 episodios de NAC, 53 por SAMR-AC y 197 por otros agentes. Los pacientes con SAMR fueron más jóvenes (35,6±13,4 vs 43,1±12,4, p<0,001) y mostraron mayores tasas de infecciones de piel y estructuras relacionadas (IPER) (58,4% vs 2,0%, p<0,001), empiema (15,9% vs 5,0%, p=0,006), compromiso radiológico bilateral (81,1% vs 36,0%, p<0,001), promedio de score APACHE II basal (16,7±3,8 vs 13,2±4,3, p<0,001) y requerimiento de ventilación mecánica (VM) (33,9 vs 17,6 p=0,009). La tasa de mortalidad fue significativamente mayor para los pacientes con SAMR-AC (35,8% vs 11,1%, p<0,001). Las variables que se asociaron con SAMR-AC fueron IPER (OR 67,99, IC 5% 21,94-210,65), compromiso radiológico bilateral (OR 7,63, IC 95% 3,67-16,11), scoreAPACHE II ≥ 15 (OR 4,37, IC 95% 2,08-9,16), edad ≤ 35 años RESUMENTRABAJO COMPLETO(OR 3,60, IC 95% 1,77-7,29), empiema (OR 3,32, IC 95% 1,24-8,10) y VM (OR 2,85, IC 95% 1,36-5,86). Conclusión: En pacientes con NAC grave, la presencia de IPER, compromiso radiológico bilateral, score APACHE II ≥ 15, edad ≤ 35 años, empiema y VM se asociaron significativamente con mayor probabilidad de infección por SAMR-AC

ntroduction: Despite the incidence of community-acquired pneumonia (CAP) due to community acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) being less than 10%, its presence should be considered in critical patients because of its high rate of mortality.Objectives: To identify risk factors associated with CA-MRSA in patients with severe CAP.Materials and method: A retrospective, observational study analysed episodes of etiological diagnosis in patients admitted in Intensive Care Unit in a public hospital between 2006 and 2017.Results: 250 episodes of NAC were included, among which 53 were caused by SAMR-AC and 197 by other agents. Patients with MRSA were the youngest (35.6±13.4 vs 43.1±12.4, p<0.001), and showed higher rates of skin and skin-structure infections (SSSI) (58.4% vs 2.0%, p<0.001), empyema (15.9% vs 5.0%, p=0.006), bilateral radiological compromise (81.1% vs 36.0%, p<0.001), average base-line APACHE II score (16.7±3.8 vs 13.2±4.3, p<0.001) and mechanical ventilation requirement rate (MV) (33.9 vs 17.6 p=0.009). The mortality rate was significantly higher than the one in CA-MRSA patients (35.8% vs 11.1%, p<0.001). The variables associated with CA-MRSA were SSSI (OR 67.99, IC 5% 21.94-210.65), bilateral radiological compromise (OR 7.63, IC 95% 3.67-16.11), APACHE II score ≥ 15 (OR 4.37, IC 95% 2.08-9.16), age ≤35 years (OR 3.60, IC 95% 1.77-7,29), empyema (OR 3.32, IC 95% 1.24-8.10) and MV (OR 2.85, IC 95% 1.36-5.86).Conclusion: The presence of SSSI, bilateral radiological compromise, APACHE II score ≥ 15, age ≤35 years, empyema and MV in patients with severe CAP was largely associated with higher probability of CA-MRSA infection

Herbivore-Induced Volatiles from Maize Plants Attract Chelonus insularis, an Egg-Larval Parasitoid of the Fall Armyworm.

Chelonus insularis (Hymenoptera: Braconidae) is an egg-larval endoparasitoid that attacks several lepidopteran species, including the fall armyworm (FAW), Spodoptera frugiperda, as one of its main hosts. In this study, we identified the volatiles emitted by maize plants undamaged and damaged by S. frugiperda larvae that were attractive to virgin C. insularis females. In a Y-glass tube olfactometer, parasitoid females were more attracted to activated charcoal extracts than Porapak Q maize extracts. Chemical analysis of activated charcoal extracts from maize plants damaged by S. frugiperda larvae by gas chromatography coupled with electroantennography (GC-EAD) showed that the antennae of virgin female wasps consistently responded to three compounds, identified by gas chromatography-mass spectrometry (GC-MS) as α-pinene, α-longipinene and α-copaene. These compounds are constitutively released by maize plants but induction via herbivory affects their emissions. α-Longipinene and α-copaene were more abundant in damaged maize plants than in healthy ones, whereas α-pinene was produced in higher amounts in healthy maize plants than in damaged ones. Female parasitoids were not attracted to EAD-active compounds when evaluated singly; however, they were attracted to the binary blend α-pinene + α-copaene, which was the most attractive blend, even more attractive than the tertiary blend (α-pinene + α-longipinene + α-copaene) and the damaged maize plant extracts. We conclude that C. insularis is attracted to a blend of herbivore-induced volatiles emitted by maize plants.

Análisis factorial exploratorio como método multivariante para validación de datos académicos en plataformas virtuales / Exploratory factorial analysis as a multivariate method for the validation of academic data in virtual platforms / Análise fatorial exploratória como método multivariado para a validação de dados acadêmicos em plataformas virtuais

Resumen Introducción: El trabajo se establece como un resultado de investigación en el cual se realiza una revisión bibliográfica sobre la temática planteada. Objetivo: Caracterizar los materiales de clase que utiliza dos universidades una pública y una privad para la identificación de tipos de tecnologías. Materiales y Método: Se considera que el estudio es no-experimental y se espera la participaron todos los estudiantes matriculados en el primer semestre 2017, se cumple con los criterios de inclusión: a) edad mínima de 18 años; b) matriculados en sus respectivas universidades; La muestra aleatoria piloto contenía 98 participantes de un total de 2150 estudiantes de las dos universidades. Resultados: Mediante la aplicación de varias técnicas estadísticas como el análisis: Factorial Exploratorio, alfa de Cronbach clásico. Se analizó el comportamiento de las respuestas al cuestionario de 21 ítems, que tiene un formato de escala tipo Likert, definidas en 4 dimensiones. Se comprobó la inexistencia de diferencias estadísticamente significativas, en tres ítems del estudio. Conclusiones: Se ha analizado la validez y fiabilidad de dicho cuestionario a través de un análisis factorial de componentes principales con rotación Varimax. Se concluye que bastaría con introducir adaptaciones en la relación de dimensiones propuestas en este cuestionario que tuviera en cuenta las especificidades de cada material de estudio.

Abstract Introduction: The work is established as a result of research in which a bibliographic review is made on the subject matter proposed. Objective: Characterize the class materials used by two universities, one public and one private for the identification of types of technologies. Materials and Method: The study is considered non-experimental and it is expected that all students enrolled in the first semester of 2017 will participate, complying with the inclusion criteria: a) minimum age of 18; b) enrolled in their respective universities; The pilot random sample contained 98 participants out of a total of 2150 students from the two universities. Results: Through the application of several statistical techniques such as the analysis: Exploratory Factorial, classic Cronbach's alpha. The behavior of the responses to the 21-item questionnaire, which has a Likert-type scale format, was analyzed, defined in 4 dimensions. The absence of statistically significant differences was verified in three items of the study. Conclusions: The validity and reliability of this questionnaire was analyzed through a factorial analysis of principal components with Varimax rotation. It is concluded that it would be enough to introduce adaptations in the list of dimensions proposed in this questionnaire that took into account the specificities of each study material.

Resumo Introdução: O trabalho é estabelecido como resultado de uma pesquisa em que é feita uma revisão bibliográfica sobre o assunto proposto. Objetivo: caracterizando os materiais de aula utilizados por duas universidades, uma pública e outra privada para a identificação de tipos de tecnologias. Materiais e Método: O estudo é considerado não experimental e espera-se que todos os alunos matriculados no primeiro semestre de 2017 participem, obedecendo aos critérios de inclusão: a) idade mínima de 18 anos; b) matriculados em suas respectivas universidades; A amostra aleatória piloto continha 98 participantes de um total de 2150 estudantes das duas universidades. Resultados: Através da aplicação de diversas técnicas estatísticas, como a análise: Fatorial Exploratório, clássico Alfa de Cronbach. Analisou-se o comportamento das respostas ao questionário de 21 itens, que possui formato de escala tipo Likert, definido em 4 dimensões. A ausência de diferenças estatisticamente significantes foi verificada em três itens do estudo. Conclusão: A validade e confiabilidade deste questionário foram analisadas através de uma análise fatorial de componentes principais com rotação Varimax. Conclui-se que seria suficiente introduzir adaptações na lista de dimensões proposta neste questionário que levasse em consideração as especificidades de cada material de estudo.

Life quality protection rights for elderly people. communities of posorja and puna / Protección de los derechos de calidad de vida para adultos mayores. comunidades de posorja y puna / Proteção dos direitos à qualidade de vida para idosos. as comunidades de posorja e puna

Abstract Background: The present article aims to measure the extent to which the physical and recreational needs of elderly persons in the communities of Posorja and Puna are being met. Nowadays, it is known that physical activity is beneficial for the elderly, as it helps to diminish illness and all kinds of diseases. Method: The population in this study is comprised on 378 elderly persons between 65 and 90 years of age: 200 belong to the community of Posorja and 178, to the community of Puna in Guayas Province. The tools used for this research include, among others, the ADL Test (Activities of Daily Living), which evaluates the degree of self-care and mobility; the Lawton and Brody Scale, which is an appropriate instrument to evaluate the level of independence and skills; and the MMT (Mini Mental Test), which evaluates cognitive functions such as memory, language, praxis and attention. They all are essential to detecting and diagnosing Alzheimer´s disease. Results: Various statistical techniques were used to obtain the results, such as descriptive analysis, contingency tables and main components. Conclusions: The population between 65 and 90 years of age was analyzed and it accounted for 35.9% of the total population back in 2010, which means there was a variation. Nowadays, it represents 56.6% of the obtained sample. This generational group refers to the elderly, who should be favored by public policies that are intended to improve health programs, generate recreational areas, and create senior care centers. Generally, the demographic dynamics of Posorja show a structured pyramid, with an expanding population, a large amount of young people and adults who contribute to the economic dynamics and productivity of the area. The questionnaire could be adapted and contain the specifications required to suit the true dimensions of this population.

Resumen Antecedentes: este artículo tiene como propósito medir el grado en que se satisfacen las necesidades físicas y recreativas de los adultos mayores en las comunidades de Posorja y Puna. Hoy en día, se sabe que la actividad física es beneficiosa para los ancianos, ya que ayuda para disminuir dolencias y todo tipo de enfermedades. Método: La población en este estudio está compuesta por 378 personas mayores entre 65 y 90 años de edad: 200 pertenecen a la comunidad de Posorja y 178 a la comunidad de Puna en la provincia de Guayas. Las herramientas utilizadas para esta investigación se incluyen, entre otros, la Prueba ADL (Actividades de la vida diaria), que evalúa el grado de autocuidado y movilidad; la Escala de Lawton y Brody, que es un instrumento apropiado para evaluar el nivel de independencia y habilidades; y la MMT (Mini prueba mental), que evalúa las funciones cognitivas, como la memoria, el lenguaje, la praxis y la atención. Todos son esenciales para detectar y diagnosticar la enfermedad de Alzheimer. Resultados: Se utilizaron diversas técnicas estadísticas para obtener los resultados, como el análisis descriptivo, tablas de contingencia y componentes principales. Conclusiones: Se analizó la población entre 65 y 90 años de edad que representó el 35.9% de la población total en 2010, lo que significa que hubo una variación. Hoy en día, representa el 56.6% de la muestra obtenida. Este grupo generacional se refiere a las personas mayores, que deberían ser favorecidos por las políticas públicas que se pretenden para mejorar los programas de salud, generar áreas recreativas y crear centros de cuidado para adultos mayores. En general, la dinámica demográfica de Posorja muestra una pirámide estructurada, con una población en expansión, una gran cantidad de jóvenes y adultos que contribuyen a la dinámica económica y productividad del área. El cuestionario podría modificarse y contener las especificaciones requeridas para adaptarse a las verdaderas dimensiones de esta población.

Resumo Contexto: O presente artigo visa analisar em que medida as necessidades físicas e recreacionais dos idosos das comunidades de Posorja e Puna, no Equador, estão sendo atendidas. Atualmente, sabe-se que a atividade física é benéfica para os idosos, já que ajuda a diminuir enfermidades e todos os tipos de doenças. Metodologia: Neste estudo, a população é composta por 378 pessoas idosas com idades entre 65 e 90 anos - 200 pertencem à comunidade de Posorja e 178 à comunidade de Puna, na província de Gayas. As ferramentas utilizadas nesta pesquisa incluem, entre outras, o Teste ADL (Activities of Daily Living), que avalia o grau de autocuidado e mobilidade; a Escala de Lawton e Brody, que é um instrumento apropriado para avaliar o nível de independência e as habilidades; e o MEEM (Miniexame do Estado Mental), que avalia funções cognitivas, como a memória, a linguagem, a práxis e a atenção. Todas elas são essenciais para detectar e diagnosticar a Doença de Alzheimer. Resultados: Várias técnicas estatísticas foram usadas para obter os resultados, tais como análise descritiva, tabelas de contingência e principais componentes. Conclusões: A população entre 65 e 90 anos foi analisada e somava 35,9% da população total em 2010, o que significa que houve uma variação. Atualmente, essa população representa 56,6% da amostra obtida. Esse grupo geracional se refere aos idosos, que deveriam ser favorecidos por políticas públicas que visam melhorar programas de saúde, gerar espaços recreacionais e abrir centros especializados no cuidado de idosos. Em geral, as dinâmicas demográficas de Posorja mostram uma pirâmide estruturada com uma população em expansão, uma grande quantidade de jovens e adultos que contribuem para as dinâmicas econômicas e para a produtividade da região. O questionário poderia ser adaptado para conter as especificações requeridas para adequar-se às verdadeiras dimensões dessa população.