Primping, performing, and policing: Social media use and self-sexualization among U.S. White, Black, and Asian-American adolescent girls.

Objectification theorists argue that routine sexual objectification, experienced interpersonally and via the media, encourages women and adolescent girls to value their external appearance and sexiness above other bodily experiences and competencies. Commonly, tests of this theory have linked exposure to sexualizing media content (i.e., TV, music videos, social media) to self-objectification and subsequently to consequences such as disordered eating among predominantly White samples. Do these analyses extend to U.S. girls of color and to broader well-being consequences? Using structural equation modeling, we tested theorized connections among 884 adolescent girls aged 13-18, including 391 White girls, 248 Black girls, and 245 Asian American girls. Participants completed surveys assessing their use of several social media platforms, social media engagement, self-sexualization, mental health symptoms, self-esteem, and body shame. We also examined age, racial identity, and racial composition of peer group as moderators. The model worked as expected for the full sample, with social media use and engagement predicting greater self-sexualization, which in turn was associated with diminished well-being. However, the model fit was worse for the White girls than for girls of color, and some constructs operated differently. Implications for future research with girls and possible media interventions are discussed.

Petting Zoos as an Unsuspected Source of Pediatric Infections.

Children are at risk for infection following animal exposure at petting zoos owing to suboptimal hand hygiene and frequent hand-to-mucosal surface contact. Public health surveillance is limited, and infectious risk is likely underrecognized. Most reported infections are enteric. Here, we describe two children with unusual, nonenteric infections following petting zoo exposure.

Self-objectification: Implications for physical activity in middle-aged women and men.

Self-objectification (i.e., valuing the body primarily for its attractiveness to others) is negatively related to physical health, including physical activity (PA) attitudes and behaviors. Given the low levels of PA among middle-aged adults in the US, self-objectification may be a novel correlate of PA in this population. The present study examined self-objectification and PA variables in a cross-sectional Western U.S. community sample of women (n = 215) and men (n = 134), aged 45-64, including gender as a moderator of these relations. Data were collected via survey, including measures of self-objectification, PA enjoyment, PA perceived benefits and barriers, and self-reported levels of PA. Women and men in our sample did not differ in levels of self-objectification. Results of regression analyses indicated that self-objectification predicted less PA enjoyment. In addition, men higher in self-objectification reported higher levels of PA. The findings implicate self-objectification as a potentially novel determinant of PA attitudes and behaviors in middle-aged adults.

Variation in ampicillin dosing for lower respiratory tract infections and neonatal bacterial infections in US children's hospitals.

Objective: We examined ampicillin dosing in pediatric patients across 3 conditions: (1) bacterial lower respiratory tract infections (LRTIs) in infants and children >3 months, (2) neonates with suspected or proven sepsis, and (3) neonates with suspected central nervous system (CNS) infections. We compared our findings to dosing guidance for these specific indications. Design: Retrospective cohort study. Setting: The study included data from 32 children's hospitals in the United States. Methods: We reviewed prescriptions from the SHARPS study of antimicrobials, a survey of antibiotic prescribing from July 2016 to December 2017. Prescriptions were analyzed for indication, total daily dose per kilogram, and presence of antimicrobial stewardship program (ASP) review. LRTI prescriptions were compared to IDSA recommendations for community-acquired pneumonia. Neonatal prescriptions were compared to recommendations from the American Academy of Pediatrics (AAP). Prescriptions were categorized as "optimal" (80%-120% of recommended dosing), "suboptimal" (<80% of recommended dosing), or "excessive" (>120% of recommended dosing). Results: Among 1,038 ampicillin prescriptions, we analyzed 88 prescriptions for LRTI, 499 prescriptions for neonatal sepsis, and 27 prescriptions for neonatal CNS infection. Of the LRTI prescriptions, 77.3%were optimal. Of prescriptions for neonatal sepsis, 81.6% were excessive compared to AAP bacteremia recommendations but 78.8% were suboptimal compared to AAP meningitis guidelines. Also, 48.1% of prescriptions for neonatal CNS infection were suboptimal, and 50.6% of prescriptions were not reviewed by the ASP. Conclusions: LRTI dosing is generally within the IDSA-recommended range. However, dosing for neonatal sepsis often exceeds the recommendation for bacteremia but is below the recommendation for meningitis. This variability points to an important opportunity for future antimicrobial stewardship efforts.

"Intermission!" A short-term social media fast reduces self-objectification among pre-teen and teen dancers.

Social media use is pervasive among youth and is associated with body image disturbance and self-objectification. The present study investigated whether a 3-day social media fast in a sample for whom social media is especially salient, female adolescent dancers, can mitigate such negative effects. Through an online survey, 65 pre-teen and teen girls, aged 10-19, completed measures of self-objectification (body surveillance and body shame), self-esteem and self-compassion both prior to and following three days of abstaining from all social media. During the fast, girls reflected on their experiences in group messages on the messaging app, WhatsApp. Overall, the fast had positive effects on participants, for whom body surveillance and body shame was significantly reduced after the fast. Self-compassion significantly mediated the change in both body surveillance and body shame, and self-esteem was a significant mediator of improvements in body shame. The content of girls' group messages revealed a number of themes, such as more positive mental states during the fast. Future research should continue to examine the potential of brief social media fasts as a means to alleviate appearance pressures adolescent girls face on these platforms in daily life.

An examination of preadolescent girls' social media use and body image: Type of engagement may matter most.

Research continues to accumulate suggesting that social media use presents a risk to youths' body image, yet the majority of this research has examined late adolescents and emerging adults. This study examined 151 preadolescent girls' (M age = 12.06, SD = 1.22) social media use and associations with both positive and negative body image at two time points separated by approximately five months. Girls completed an online survey that included several body image measures and items that queried girls about the social media platforms they used and the activities they engaged in on these platforms. Findings suggest that girls who use social media do not differ significantly from girls who do not use social media in terms of their body image. However, among girls who use social media, their type of engagement (appearance-focused versus communication-focused use) is important; only girls who engage in appearance-focused social media use seem to experience negative body image concerns.

Becoming an object: A review of self-objectification in girls.

Objectification theory (Fredrickson & Roberts, 1997) provides a framework for understanding how cultural pressure on women's appearance (i.e., sexual objectification) impacts their psychological and physical well-being. Although objectification theory proposes that objectification processes commence with the onset of puberty, much of the existing research on self-objectification has been conducted with adult women. Thus, less is known about how self-objectification operates with younger girls and adolescent girls. In this paper, we provide a comprehensive review of self-objectification research on girls under the age of 18 including the prevalence, predictors, and outcomes of self-objectification as well as protective factors (n = 66 studies). In addition, we discuss how development is relevant to objectification theory and self-objectification. Finally, we call for a program of research that addresses methodological and conceptual concerns in existing research, fills gaps in the research literature, and pays further attention to developmental processes in self-objectification. An especially notable pattern we identified is that self-objectification is strongly related to age, such that older girls experience higher levels of self-objectification compared to younger girls. The aim of this paper is to provoke deeper considerations of development and the inclusion of girls in future research on self-objectification.

Exposure to thin-ideal media affect most, but not all, women: Results from the Perceived Effects of Media Exposure Scale and open-ended responses.

Findings conflict as to whether thin-ideal media affect women's body satisfaction. Meta-analyses of experimental studies reveal small or null effects, but many women endorse appearance-related media pressure in surveys. Using a novel approach, two samples of women (Ns=656, 770) were exposed to bikini models, fashion models, or control conditions and reported the effects of the images their body image. Many women reported the fashion/bikini models made them feel worse about their stomachs (57%, 64%), weight (50%, 56%), waist (50%, 56%), overall appearance (50%, 56%), muscle tone (46%, 52%), legs (45%, 48%), thighs (40%, 49%), buttocks (40%, 43%), and hips (40%, 46%). In contrast, few women (1-6%) reported negative effects of control images. In open-ended responses, approximately one-third of women explicitly described negative media effects on their body image. Findings revealed that many women perceive negative effects of thin-ideal media in the immediate aftermath of exposures in experimental settings.

Grooming ten-year-olds with gender stereotypes? A content analysis of preteen and teen girl magazines.

Extensive research shows a strong body focus in media aimed at teen girls and adult women; less is known about the content of media aimed at preteen girls. The present study investigated differences in the content of preteen versus teen girl magazines. Additionally, the content of independent compared to mainstream magazines was examined. Media frames, which are dominant themes present in media stories, used in content about the body were examined. Finally, the prevalence of appearance-focused versus non-appearance-focused content was assessed. Advertisements and general stories were analyzed. Results indicate that teen and mainstream magazines contained more appearance content than preteen and independent magazines. Appearance media frames were more common in teen than preteen magazines. Finally, teen and mainstream magazines contained more appearance-focused than non-appearance-focused content, whereas the opposite was true for preteen and independent magazines. Findings are discussed in terms of objectification theory and gender socialization practices.

"I am not a skinny toothpick and proud of it": Latina adolescents' ethnic identity and responses to mainstream media images.

Using a quasi-experimental design, 118 Latina girls, ages 13-18, viewed five color photographs of White women. Girls viewed either images of sexualized women or images of non-sexualized women. After viewing the images, girls were asked to complete the sentence stem, "I am…" 20 times. Thirty percent of girls spontaneously described their ethnicity in one of their sentence completions. Spontaneous use of ethnicity was taken as an indicator of the salience of ethnic identity. Among girls who viewed sexualized, thin-ideal White media images, spontaneously using an ethnic descriptor was related to more positive descriptions of one's own body and appearance. Analyses supported the premise that ethnic identity may act as a protective factor, buffering Latina girls from the negative effects of viewing sexualized, thin-ideal White media images.

Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer.

Etiologic factors for pancreatic cancer, the 4th deadliest malignant neoplasm in the United States, include obesity and abnormal glucose metabolism. Calorie restriction (CR) and rapamycin each affect energy metabolism and cell survival pathways via inhibition of mammalian target of rapamycin (mTOR) signaling. By using a Panc02 murine pancreatic cancer cell transplant model in 45 male C57BL/6 mice, we tested the hypothesis that rapamycin mimics the effects of CR on pancreatic tumor growth. A chronic regimen of CR, relative to an ad libitum-fed control diet, produced global metabolic effects such as reduced body weight (20.6 ± 1.6 g vs. 29.3 ± 2.3 g; P < 0.0001), improved glucose responsiveness, and decreased circulating levels of insulin-like growth factor (IGF)-1 (126 ± 8 ng/mL vs. 199 ± 11 ng/mL; P = 0.0006) and leptin (1.14 ± 0.2 ng/mL vs. 5.05 ± 1.2 ng/mL; P = 0.01). In contrast, rapamycin treatment (2.5 mg/kg intraperitoneal every other day, initiated in mice following 20 weeks of ad libitum control diet consumption), relative to control diet, produced no significant change in body weight, IGF-1 or leptin levels, but decreased glucose responsiveness. Pancreatic tumor volume was significantly reduced in the CR group (221 ± 107 mm(3); P < 0.001) and, to a lesser extent, the rapamycin group (374 ± 206 mm(3); P = 0.04) relative to controls (550 ± 147 mm(3)), and this differential inhibition correlated with expression of the proliferation marker Ki-67. Both CR and rapamycin decreased phosphorylation of mTOR, p70/S6K, and S6 ribosomal protein, but only CR decreased phosphorylation of Akt, GSK-3ß, extracellular signal regulated kinase/mitogen-activated protein kinase, and STAT3(TYR705). These findings suggest that rapamycin partially mimics the anticancer effects of CR on tumor growth in a murine model of pancreatic cancer.

Genetic reduction of insulin-like growth factor-1 mimics the anticancer effects of calorie restriction on cyclooxygenase-2-driven pancreatic neoplasia.

Risk of pancreatic cancer, the fourth deadliest cancer in the United States, is increased by obesity. Calorie restriction (CR) prevents obesity, suppresses carcinogenesis in many models, and reduces serum levels of IGF-1. In the present study, we examined the impact of CR on a model of inflammation-associated pancreatitis and pancreatic dysplasia, with a focus on the mechanistic contribution of systemic IGF-1. Administration of a 30% CR diet for 14 weeks decreased serum IGF-1 levels and hindered pancreatic ductal lesion formation and dysplastic severity, relative to a higher calorie control diet, in transgenic mice overexpressing COX-2 [bovine keratin-5 promoter (BK5.COX-2)]. These findings in CR mice correlated with reductions in Ki-67-positive cells, vascular luminal size, VEGF expression, and phosphorylation and total expression of downstream mediators of the IGF-1 pathway. Cell lines derived from BK5.COX-2 ductal lesions (JC101 cells) formed pancreatic tumors in wild-type FVB mice that were significantly reduced in size by a 14-week CR regimen, relative to the control diet. To further understand the impact of circulating levels of IGF-1 on tumor growth in this model, we orthotopically injected JC101 cells into liver-specific IGF-1-deficient (LID) mice. The approximate 65% reduction of serum IGF-1 levels in LID mice resulted in significantly decreased burden of JC101 tumors, despite modestly elevated levels of circulating insulin and leptin. These data show that CR prevents development of dysplasia and growth of pancreatic cancer through alterations in IGF-1, suggesting that modulation of this pathway with dietary and/or pharmacologic interventions is a promising pancreatic cancer prevention strategy.