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1.
PNAS Nexus ; 2(8): pgad246, 2023 Aug.
Article in English | MEDLINE | ID: mdl-37564362

ABSTRACT

The COVID-19 pandemic brought upon a massive wave of disinformation, exacerbating polarization in the increasingly divided landscape of online discourse. In this context, popular social media users play a major role, as they have the ability to broadcast messages to large audiences and influence public opinion. In this article, we make use of openly available data to study the behavior of popular users discussing the pandemic on Twitter. We tackle the issue from a network perspective, considering users as nodes and following relationships as directed edges. The resulting network structure is modeled by embedding the actors in a latent social space, where users closer to one another have a higher probability of following each other. The results suggest the existence of two distinct communities, which can be interpreted as "generally pro" and "generally against" vaccine mandates, corroborating existing evidence on the pervasiveness of echo chambers on the platform. By focusing on a number of notable users, such as politicians, activists, and news outlets, we further show that the two groups are not entirely homogeneous, and that not just the two poles are represented. To the contrary, the latent space captures an entire spectrum of beliefs between the two extremes, demonstrating that polarization, while present, is not the only driver of the network, and that more moderate, "central" users are key players in the discussion.

2.
Adv Stat Anal ; 106(3): 407-426, 2022.
Article in English | MEDLINE | ID: mdl-35069920

ABSTRACT

Governments around the world continue to act to contain and mitigate the spread of COVID-19. The rapidly evolving situation compels officials and executives to continuously adapt policies and social distancing measures depending on the current state of the spread of the disease. In this context, it is crucial for policymakers to have a firm grasp on what the current state of the pandemic is, and to envision how the number of infections is going to evolve over the next days. However, as in many other situations involving compulsory registration of sensitive data, cases are reported with delay to a central register, with this delay deferring an up-to-date view of the state of things. We provide a stable tool for monitoring current infection levels as well as predicting infection numbers in the immediate future at the regional level. We accomplish this through nowcasting of cases that have not yet been reported as well as through predictions of future infections. We apply our model to German data, for which our focus lies in predicting and explain infectious behavior by district. Supplementary Information: The online version contains supplementary material available at 10.1007/s10182-021-00433-5.

3.
Biom J ; 63(8): 1623-1632, 2021 12.
Article in English | MEDLINE | ID: mdl-34378235

ABSTRACT

The case detection ratio of coronavirus disease 2019 (COVID-19) infections varies over time due to changing testing capacities, different testing strategies, and the evolving underlying number of infections itself. This note shows a way of quantifying these dynamics by jointly modeling the reported number of detected COVID-19 infections with nonfatal and fatal outcomes. The proposed methodology also allows to explore the temporal development of the actual number of infections, both detected and undetected, thereby shedding light on the infection dynamics. We exemplify our approach by analyzing German data from 2020, making only use of data available since the beginning of the pandemic. Our modeling approach can be used to quantify the effect of different testing strategies, visualize the dynamics in the case detection ratio over time, and obtain information about the underlying true infection numbers, thus enabling us to get a clearer picture of the course of the COVID-19 pandemic in 2020.


Subject(s)
COVID-19 , Pandemics , Humans , Models, Statistical , SARS-CoV-2
4.
Biom J ; 63(3): 471-489, 2021 03.
Article in English | MEDLINE | ID: mdl-33215765

ABSTRACT

We analyse the temporal and regional structure in mortality rates related to COVID-19 infections, making use of the openly available data on registered cases in Germany published by the Robert Koch Institute on a daily basis. Estimates for the number of present-day infections that will, at a later date, prove to be fatal are derived through a nowcasting model, which relates the day of death of each deceased patient to the corresponding day of registration of the infection. Our district-level modelling approach for fatal infections disentangles spatial variation into a global pattern for Germany, district-specific long-term effects and short-term dynamics, while also taking the age and gender structure of the regional population into account. This enables to highlight areas with unexpectedly high disease activity. The analysis of death counts contributes to a better understanding of the spread of the disease while being, to some extent, less dependent on testing strategy and capacity in comparison to infection counts. The proposed approach and the presented results thus provide reliable insight into the state and the dynamics of the pandemic during the early phases of the infection wave in spring 2020 in Germany, when little was known about the disease and limited data were available.


Subject(s)
COVID-19/mortality , Adult , Aged , Aged, 80 and over , Female , Germany/epidemiology , Humans , Male , Middle Aged , Pandemics/statistics & numerical data , Spatio-Temporal Analysis
5.
Brain Sci ; 10(12)2020 Nov 27.
Article in English | MEDLINE | ID: mdl-33260987

ABSTRACT

On 11 March 2020, a national lockdown was imposed by the Italian government to contain the spread of COVID19 disease. This is an observational longitudinal study conducted at Fondazione Stella Maris (FSM), Italy to investigate lockdown-related emotional and behavioural changes in paediatric neuropsychiatric population. Families having children (1.5-18 years) with neuropsychiatric disorders referred to FSM have been contacted and proposed to fulfil two online questionnaires (General questionnaire and Child Behaviour Check List (CBCL)) to (i) compare (paired two-sample t-tests) the CBCL scores during lockdown with previous ones, and (ii) investigate the influence (multiple linear regression models) of variables such as age, diagnosis grouping (neurological, neurodevelopmental, emotional, and behavioural disorders) and financial hardship. One hundred and forty-one parents fulfilled the questionnaires. Anxiety and somatic problems increased in 1.5-5 years subpopulation, while obsessive-compulsive, post-traumatic and thought problems increased in 6-18 years subpopulation. In the regression models, younger age in the 1.5-5 years subpopulation resulted as "protective" while financial hardship experienced by families during lockdown was related to psychiatric symptoms increasing in the 6-18 years subpopulation. Some considerations, based on first clinical impressions, are provided in text together with comments in relation to previous and emerging literature on the topic.

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