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Korean J Gastroenterol ; 83(6): 247-252, 2024 Jun 25.
Article in English | MEDLINE | ID: mdl-38918038

ABSTRACT

Toxocariasis, a zoonotic infection transmitted by Toxocara canis (from dogs) and Toxocara cati (from cats) larvae, poses rare but severe risks to humans. We present a case of hepatic visceral larva migrans (VLM) caused by Toxocara canis in a 21-year-old male with a history of close contact with a pet dog. Initial symptoms and imaging findings mimicked a pyogenic liver abscess. The initial laboratory investigations revealed neutrophilia and elevated levels of IgE. Despite broad-spectrum antibiotics, persistent fever prompted further investigation. Subsequent serological testing for Toxocara antibodies and histopathological analysis of liver tissue demonstrating eosinophil infiltrates and Charcot-Leyden crystals led to a confirmed diagnosis of a liver abscess caused by Toxocara canis. Serological testing for Toxocara antibodies and histopathological analysis of liver tissue confirmed a Toxocara canis-induced liver abscess. Albendazole treatment yielded significant clinical improvement. This case highlights the necessity of considering toxocariasis in liver abscess differentials, particularly in high-seroprevalence regions like Vietnam. Relying solely on serological tests may be insufficient, emphasizing the need for corroborative evidence, including invasive procedures like liver biopsy, for accurate hepatic toxocariasis diagnosis.


Subject(s)
Albendazole , Larva Migrans, Visceral , Tomography, X-Ray Computed , Toxocara canis , Humans , Toxocara canis/isolation & purification , Larva Migrans, Visceral/diagnosis , Larva Migrans, Visceral/drug therapy , Male , Animals , Young Adult , Albendazole/therapeutic use , Dogs , Liver/parasitology , Liver/pathology , Antibodies, Helminth/blood , Ultrasonography , Liver Abscess/diagnosis , Liver Abscess/parasitology , Liver Abscess/drug therapy , Toxocariasis/diagnosis , Toxocariasis/drug therapy , Immunoglobulin E/blood , Anthelmintics/therapeutic use
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