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1.
BMJ Case Rep ; 13(2)2020 Feb 28.
Article in English | MEDLINE | ID: mdl-32114496

ABSTRACT

A 43-year-old man with Austrian syndrome, the triad of infective endocarditis (IE), pneumonia and meningitis caused by Streptococcus pneumoniae, underwent emergency aortic and mitral valve replacement and closure of an aortic root abscess. Postoperatively, he required mechanical circulatory support with veno-arterial extracorporeal membrane oxygenation and an intra-aortic balloon pump. Several days after surgery, new mitral and aortic paraprosthetic leaks (PPLs) developed. These were managed conservatively, initially, but eventually required percutaneous closure 6 weeks after the initial operation. This has enabled the patient to recover to independent mobility, 20 weeks after the operation. This case illustrates a rare clinical syndrome and the devastating impact of IE. Moreover, it illustrates the successful application of extracorporeal membrane oxygenation in postcardiotomy cardiac failure and the successful treatment of PPL in a patient unfit for redo surgery.


Subject(s)
Endocarditis/microbiology , Endocarditis/therapy , Extracorporeal Membrane Oxygenation , Meningitis/microbiology , Meningitis/therapy , Pneumonia, Bacterial/therapy , Adult , Anti-Bacterial Agents/therapeutic use , Antibiotics, Antitubercular/therapeutic use , Heart Valve Prosthesis , Humans , Intra-Aortic Balloon Pumping , Male , Streptococcus pneumoniae , Syndrome
2.
BMJ Case Rep ; 20182018 Sep 15.
Article in English | MEDLINE | ID: mdl-30219782

ABSTRACT

We present the case of a 23-year-old woman with a long-standing history of recurrent left-sided pleural effusion unrelated to her menstrual cycle. At her last presentation, non-contrast-enhanced chest CT showed a pleural effusion and a lower left hemithorax mass, both large enough to cause complete collapse of the lower lobe and partial collapse of the upper lobe. Thoracoscopic surgery revealed a multilobulated mass originating from the dome of the diaphragm with pleural deposits. Histopathology diagnosed this as a calcifying fibrous tumour of the pleura, a rare benign tumour with excellent prognosis when completely excised.


Subject(s)
Neoplasms, Fibrous Tissue/pathology , Solitary Fibrous Tumor, Pleural/pathology , Adult , Biopsy , Female , Humans , Neoplasms, Fibrous Tissue/diagnostic imaging , Neoplasms, Fibrous Tissue/surgery , Pleural Effusion/complications , Pleural Effusion/diagnostic imaging , Pneumothorax , Solitary Fibrous Tumor, Pleural/surgery , Tomography, X-Ray Computed
5.
F1000Prime Rep ; 6: 27, 2014.
Article in English | MEDLINE | ID: mdl-24904750

ABSTRACT

Heart failure (HF) is a growing cause of morbidity and mortality globally. All clinical therapies that reduce mortality have been shown to induce reverse remodeling. In this article, we discuss a conceptual approach to the evolving treatment of HF using emerging treatment modalities for the drug-refractory patient. This approach is based on the combinatorial, integrated application of therapies shown to influence reverse remodeling in the laboratory.

6.
J Thorac Cardiovasc Surg ; 146(6): 1321-6, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24094917

ABSTRACT

BACKGROUND: The clinical environment is becoming increasingly dominated by information technology, most recently the smartphone with its applications (apps) of a multitude of uses. There are already tens of thousands of medical apps available for download, to educate both patients and trainees, and many more are being designed to facilitate delivery of care. The rapid development of this technology has outgrown its quality evaluation and regulation, both urgently required to maintain patient safety, protect sensitive data, and ensure dissemination of accurate information. We review medical apps themed towards cardiothoracic surgery in terms of medical professional involvement in their content and design. METHODS: iTunes and Play Store were searched for cardiothoracic surgery-themed medical apps, using the terms cardiothoracic, thoracic, cardiac, heart, lung, surgery, and variations thereof and including the term medical. RESULTS: A focused search yielded 379 apps, of which 6% were associated with a named medical professional, 15% with a publisher or professional society, and 63% with a user rating. CONCLUSIONS: The findings suggest inadequate input from the medical profession. The article discusses the pressing issues regarding quality evaluation, regulation, and information security, required for smartphones and handheld devices to become an integral and safe part of delivery of care.


Subject(s)
Audiovisual Aids , Cardiac Surgical Procedures/education , Cell Phone , Computer-Assisted Instruction/instrumentation , Computers, Handheld , Education, Medical, Graduate/methods , Mobile Applications , Thoracic Surgical Procedures/education , Access to Information , Audiovisual Aids/standards , Cardiac Surgical Procedures/standards , Cell Phone/standards , Computer Security , Computer-Assisted Instruction/standards , Computers, Handheld/standards , Curriculum , Diffusion of Innovation , Education, Medical, Graduate/standards , Humans , Mobile Applications/standards , Practice Guidelines as Topic , Quality Control , Thoracic Surgical Procedures/standards
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