ABSTRACT
Granular cell tumors (GCTs) are rare, indolent neoplasms classically characterized by eosinophilic granular cytoplasm, infiltrations of polygonal cells in the collagenous stroma, and pustulo-ovoid bodies of Milian. We describe a case of a 10-year-old female presenting with a GCT of the upper arm, remarkable for positive Melan-A expression without additional melanocytic features. The differentiation between granular cells versus melanocytic neoplasms carries significant implications for clinical management, and such diagnoses should be considered carefully in the setting of unusual immunophenotypes.
Subject(s)
Granular Cell Tumor , MART-1 Antigen , Skin Neoplasms , Humans , Female , Skin Neoplasms/pathology , Skin Neoplasms/metabolism , Child , Granular Cell Tumor/pathology , Granular Cell Tumor/metabolism , Granular Cell Tumor/diagnosis , MART-1 Antigen/metabolism , Biomarkers, Tumor/metabolismABSTRACT
This procedural report details the case of a 10-year-old boy with oral Crohn's disease successfully treated with intralesional corticosteroid injections. The intervention used topical anesthesia with a eutectic mixture of lidocaine 2.5%/prilocaine 2.5% cream followed by intralesional triamcinolone acetonide. This approach safely and effectively reduced patient discomfort while allowing for an acceptable and durable clinical outcome.