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1.
Diabetes Metab Syndr Obes ; 17: 825-832, 2024.
Article in English | MEDLINE | ID: mdl-38380274

ABSTRACT

Background: Diabetes is a global health challenge with escalating prevalence rates. Cardiovascular complications represent the leading cause of mortality among individuals with diabetes. Notably, dyslipidemia stands as a prominent risk factor for cardiovascular disease in Type 2 diabetes mellitus (T2DM) patients. Timely detection and management of dyslipidemia in these patients hold the potential to deter its progression and substantially reduce the risk of cardiovascular-related morbidity and mortality. This study was aimed at assessing the burden of dyslipidemia and determinant factors among T2DM patients who were being followed at the Endocrinology clinic of Hawassa University Comprehensive Specialized Hospital (HUCSH). Methodology: An Institutional- based retrospective cross-sectional study was conducted, and samples of 228 patients were selected using a systematic random sampling technique. Data were collected through structured face-to-face interviews using a questionnaire. Bivariate logistic analysis was utilized, and variables with a p-value < 0.25 in this analysis were considered candidates for multivariate logistic analysis. Multivariate logistic regression was employed to identify factors associated with the prevalence of dyslipidemia, with a significance threshold set at p < 0.05. Results: The research revealed an overall prevalence of dyslipidemia among the study participants at 75.9%. The specific manifestations of dyslipidemia were observed as follows: hypertriglyceridemia in 43%, hypercholesterolemia in 25%, elevated low-density lipoprotein in 59.2%, and reduced high-density lipoprotein in 33.3% of the study participants. Factors significantly associated with dyslipidemia included longer diabetes duration, poor physical activity, elevated HbA1C, and obesity. Conclusion: This study underscores a notably high prevalence of dyslipidemia among T2DM patients. The findings highlight the advocate for clinicians to prioritize routine screening, and effective treatment concerning dyslipidemia and its associated risk factors among individuals with T2DM. It is worth mentioning that this study was conducted in a specific hospital setting and limited time, and hence the findings, and generalizability to other healthcare facilities should be taken cautiously.

2.
Reprod Health ; 20(1): 39, 2023 Mar 08.
Article in English | MEDLINE | ID: mdl-36890509

ABSTRACT

BACKGROUND: Immediate postpartum intra-uterine contraceptive device (IPPIUCD) placement within 10 min after the expulsion of the placenta following vaginal delivery is a safe and effective method when provided after comprehensive counseling. Studies on its acceptance and utilization are scarce in the study area. This study aims to assess the acceptance and utilization of IPPIUCD. METHODS: A cross-sectional study was conducted from January 1st up to February 31st, 2020, among 392 mothers who delivered at public health facilities in Hawassa city. EPI-Data version 7.2 was used for data entry and STATA 14 for analysis. Data were collected using an interviewer administered structured questionnaire. A binary logistic regression and a multivariable logistic regression model were used to assess association. Statistical significance was determined at a p-value of less than 0.05 with a 95% confidence interval. RESULTS: Of the 392 mothers enrolled, 16.3% (95% CI: 12.7-20.0) of them accepted immediate post-partum IUCD. However, only 10% (95%CI: 7.0, 12.9) utilized immediate post-partum IUCD. Counseling about IPPIUCD, Attitude, plan to have another child, and birth intervals were associated with acceptance of immediate PPIUCD while husband support for family planning use, delivery time, and the number of children had a significant association with utilization of immediate PPIUCD. CONCLUSIONS: The study found a relatively low proportion of acceptors and utilizers of immediate post-partum IUCD in the study area. To improve the acceptance and utilization of immediate PPIUCD among mothers, all stakeholders concerned with family planning need to mitigate and promote the challenges and facilitating factors, respectively.


Immediate post-partum intrauterine contraceptive device (IPPIUCD) is a safe and effecti ve family planning method to prevent unintended pregnancy for a long time, by making the mother protected immediately after delivery before she leaves the postnatal room. Since it was a newly initiated program in Ethiopia, the proportion of mothers accepting and utilizing IPPIUCD and what factors should be the factors to acceptance and utilization were not well known. Previous studies were either from sole facility data or focused on postnatal family planning in general. This study was intended to assess acceptance, utilization, and related factors about IPPIUCD in 392 women delivered in five public health facilities. The facilities range from health centers to general and referral hospitals, providing immediate post-partum IUCD, free of charge without the need of returning for family planning methods. The proportion of women who accepted and utilized IPPIUCD was very low. Receiving information about IPPIUCD through counseling and a favorable attitude about IUCD resulted in better acceptance of PPICD than not being counseled and having an unfavorable attitude. Additionally, mothers with short birth intervals, due to fear of early pregnancy and wanting to limit pregnancy due to having a sufficient number of children were better acceptance than their counterparts. More utilization was observed among women who gave birth in the daytime, having satisfied the demand for childbirth and husband support for family planning use. To increase acceptance and utilization of IPPIUCD health professionals should provide counseling about IPPIUCD for all women, including their husbands. We have to consider family planning equally in daytime and nighttime services.


Subject(s)
Intrauterine Devices , Mothers , Pregnancy , Female , Child , Humans , Ethiopia , Cross-Sectional Studies , Postpartum Period , Family Planning Services , Health Facilities
3.
PLoS One ; 18(3): e0282478, 2023.
Article in English | MEDLINE | ID: mdl-36857375

ABSTRACT

INTRODUCTION: Since COVID-19 was announced as a worldwide pandemic, the world has been struggling with this disease. In Ethiopia, there is some information on the epidemiological characteristics of the disease and treatment outcomes of COVID-19 patients. But, there is limited evidence related to predictors of death in COVID-19 patients. OBJECTIVE: To assess the predictor of death among severely ill COVID-19 patients admitted in Hawassa city COVID-19 treatment centers. METHODS: An institution-based unmatched case-control study was conducted at Hawassa city COVID-19 treatment centers from May 2021 to June 2021. All severe COVID-19-related deaths from May 2020 to May 2021 were included in the case group whereas randomly selected discharged severe COVID-19 patients were included in the control group. Extracted information was entered into Epi-data 4.6 and exported to SPSS 25 for analysis. Multivariable binary logistic regression was run to assess predictors. The result was presented as an adjusted odds ratio with a 95% confidence interval. Variables with a 95% confidence interval which not included one were considered statistically significant. RESULT: A total of 372 (124 cases and 248 controls) patients were included in the study. Multivariable analysis revealed age ≥ 65 years (AOR = 2.62, 95% CI = 1.33-5.14), having shortness of breath (AOR = 1.87, 95% CI = 1.02-3.44), fatigue (AOR 1.78, 95% CI = 1.09-2.90), altered consciousness (AOR 3.02, 95% CI = 1.40, 6.49), diabetic Mellitus (AOR = 2.79, 95% CI = 1.16-6.73), chronic cerebrovascular disease (AOR = 2.1, 95% CI = 1.23, 3.88) were found to be predictors of death. CONCLUSION: Older age, shortness of breath, fatigue, altered consciousness, and comorbidity were predictors of death in Severe COVID-19 patients.


Subject(s)
COVID-19 Drug Treatment , COVID-19 , Humans , Aged , Case-Control Studies , Ethiopia , Dyspnea , Fatigue
4.
Ital J Pediatr ; 46(1): 70, 2020 May 24.
Article in English | MEDLINE | ID: mdl-32448252

ABSTRACT

BACKGROUND: Human Immunodeficiency Virus (HIV) infection and low birth weight (LBW) continue to be significant public health concerns in many low-income countries including Ethiopia. Yet the effect of maternal HIV infection on birth weight has not been thoroughly explored and the existing studies reported opposing findings. We examined the association between maternal HIV infection and LBW in a tertiary hospital in Southern Ethiopia. METHODS: A retrospective cohort study was conducted based on the medical records of 277 HIV-negative and 252 HIV-positive mothers who gave singleton live birth between September 2014 to August 2017 in Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia. The recodes were identified using systematic sampling approach and relevant information were extracted by using pretested extraction form. Multivariable binary logit model was fitted to examine the relationship between the exposure and outcome while adjusting for potential confounders. Adjusted odds ratio (AOR) and 95% confidence intervals (CI) is used for summarizing the findings of the analysis. RESULTS: The mean (± standard deviation) birth weight of infants born to HIV-negative women (3.1 ± 0.7 kg) was significantly higher than those born to HIV-positive counterparts (3.0 ± 0.6 kg) (p = 0.020). The prevalence of LBW was also significantly higher in the HIV-exposed group (22.2%) than the non-exposed group (13.7%) (p = 0.011). In the logit model adjusted for multiple covariates, HIV-positive women had four times increased odds than HIV-negative women to give birth to LBW infant(AOR = 4.03, 95% CI: 2.01-8.06). Other significant predictors of LBW were rural place of residence (AOR = 2.04, 95% CI: 1.16-3.60), prenatal anemia (AOR = 3.17, 95% CI: 1.71-5.90), chronic hypertension (AOR = 3.68, 95% CI: 1.10-12.46) and preeclampsia (AOR = 6.80, 95% CI: 3.00-15.38). CONCLUSION: Maternal HIV infection is associated with increased odds of LBW. HIV prevention activities are also likely to contribute for the reduction of LBW.


Subject(s)
Birth Weight , HIV Infections/complications , Pregnancy Complications, Infectious/virology , Adolescent , Adult , Ethiopia , Female , Humans , Infant, Low Birth Weight , Infant, Newborn , Logistic Models , Male , Odds Ratio , Pregnancy , Pregnancy Complications, Infectious/epidemiology , Prenatal Care , Retrospective Studies , Socioeconomic Factors , Tertiary Care Centers , Young Adult
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