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1.
J Radiol Prot ; 38(2): 716-730, 2018 Jun.
Article in English | MEDLINE | ID: mdl-29532785

ABSTRACT

This work describes the radiation characterisation and dosimetric measurements performed on the low-energy micromachining station of the femtosecond STELA (Santiago TErawatt LAser) at the University of Santiago de Compostela (Spain). For this aim, ionisation chambers, solid state detectors, and radiochromic films were used. The results show the emission of pulsed x-ray produced by laser-accelerated electrons from the ablated material exhibiting both bremsstrahlung and characteristic radiation. Although this radiation was produced unintentionally, a high superficial dose rate can be achieved. This radiation can be successfully stopped using small shielding to protect personnel from its effects. Based on the results of this work, the yearly dose equivalent after installing the shielding was negligible.


Subject(s)
Laser Therapy/methods , Radiometry/methods
2.
Opt Express ; 25(12): 13372-13381, 2017 Jun 12.
Article in English | MEDLINE | ID: mdl-28788874

ABSTRACT

We present the isolation of single attosecond pulses for multi-cycle and few-cycle laser pulses from high harmonic generation in overdense plasmas, calculated with particle-in-cell simulations. By the combination of two laser pulses of equal amplitude and a small frequency shift between them, we demonstrate that it is possible to shorten the region in which the laser pulse is most intense, therefore restricting the generation of high harmonic orders in the form of attosecond pulses to a narrower time window. The creation of this window is achieved due to the combination of the laser pulse envelope and the slow oscillating wave obtained from the coherent sum of the two pulses. A parametric scan, performed with particle-in-cell simulations, reveals how the pulse isolation behaves for different input laser pulse lengths and which are the optimal frequency shifts between the two laser pulses in each case, giving the conditions for having a good isolation of an attosecond pulse when working with laser-plasma interaction in overdense targets.

3.
Opt Express ; 25(13): 14974-14985, 2017 Jun 26.
Article in English | MEDLINE | ID: mdl-28788933

ABSTRACT

Plasmon resonances are known to amplify the electromagnetic fields near metallic nanostructures, providing a promising scheme to generate extreme-ultraviolet harmonics using low power drivings. During high-order harmonic generation (HHG), the driving and harmonic fields accumulate a phase difference as they propagate through the target. In a typical set-up -a laser focused into a gas jet- the propagation distances amount to several wavelengths, and the cumulative phase-mismatch affects strongly the efficiency and properties of the harmonic emission. In contrast, HHG in metallic nanostructures is considered to overcome these limitations, as the common sources of phase mismatch -optical density and focusing geometry- are negligible for subwavelength propagation distances. We demonstrate that phase matching still plays a relevant role in HHG from nanostructures due to the non-perturbative character of HHG, that links the harmonic phase to the intensity distribution of the driving field. Our computations show that widely used applications of phase matching control, such as quantum path selection and the increase of contrast in attosecond pulse generation, are also feasible at the nanoscale.

4.
Biofabrication ; 9(2): 025033, 2017 Jun 07.
Article in English | MEDLINE | ID: mdl-28393759

ABSTRACT

In this work a method for fabricating functionalized preclinical devices is presented. The manufacturing process combines a laser indirect writing technique to fabricate a soda-lime glass master and soft-lithography methods to obtain the final structure in polydimethylsiloxane (PDMS). The roughness of the device is modified in a controlled manner by applying a post-thermal treatment to the master, and thus devices with different roughness values are created. The PDMS devices are fully covered with human umbilical vein cells in a two-step process. In order to determine the most suitable device to perform bioassays, the cell attachment to the channel is evaluated with regards to the walls roughness when flow experiments are carried out.


Subject(s)
Biomedical Research , Lasers , Models, Cardiovascular , Tissue Engineering , Biocompatible Materials , Biomedical Research/instrumentation , Biomedical Research/methods , Calcium Compounds , Cells, Cultured , Equipment Design , Human Umbilical Vein Endothelial Cells , Humans , Oxides , Sodium Hydroxide , Tissue Engineering/instrumentation , Tissue Engineering/methods
6.
Opt Express ; 14(19): 8765-71, 2006 Sep 18.
Article in English | MEDLINE | ID: mdl-19529258

ABSTRACT

We report the use of laser ablation of metal targets onto a glass substrate as a way of producing waveguiding devices. In the geometry employed, the nanosecond pulses used for the ablation pass through the glass substrate, and are focused on the metal surface, which is located in close proximity with the substrate. We present measurements of the refractive index profile obtained with this technique, and present a discussion of the physical mechanisms that produce the profiles measured.

7.
Opt Lett ; 27(23): 2064-6, 2002 Dec 02.
Article in English | MEDLINE | ID: mdl-18033442

ABSTRACT

The fractional Talbot effect is demonstrated inside a standard 0.25-pitch Selfoc gradient-index lens under uniform illumination. Comparisons with theoretical expressions of positions and magnification of fractional Talbot images are given.

8.
J Opt Soc Am A Opt Image Sci Vis ; 18(11): 2707-16, 2001 Nov.
Article in English | MEDLINE | ID: mdl-11688861

ABSTRACT

An interpretation of the Talbot effect in a tapered gradient-index medium by number theory as the output/input relationship between the integer and the noninteger difference of position and the slope of rays is presented. Unit cell and transverse magnification for Talbot images are evaluated, and two criteria for angular magnification are defined. The study is particularized to a finite set of diffracted rays.

9.
Appl Opt ; 39(13): 2145-51, 2000 May 01.
Article in English | MEDLINE | ID: mdl-18345119

ABSTRACT

Nonparaxial diffraction-limited propagation of light with amplitude distribution in hyperbolic functions through an inhomogeneous planar medium with a hyperbolic secant refractive-index profile is studied by means of the stationary phase method. The irradiance distribution at geometrical shadow, edge of shadow, and a geometrically illuminated region is analyzed for a particular case.

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