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Ann Nucl Med ; 28(8): 824-8, 2014 Oct.
Article in English | MEDLINE | ID: mdl-24777651

ABSTRACT

BACKGROUND: The beta and gamma absorbed fractions in organs and tissues are the important key factors of radionuclide internal dosimetry based on Medical Internal Radiation Dose (MIRD) approach. OBJECTIVES: The aim of this study is to find suitable analytical functions for beta and gamma absorbed fractions in spherical and ellipsoidal volumes with a uniform distribution of iodine-131 radionuclide. METHODS: MCNPX code has been used to calculate the energy absorption from beta and gamma rays of iodine-131 uniformly distributed inside different ellipsoids and spheres, and then the absorbed fractions have been evaluated. RESULTS: We have found the fit parameters of a suitable analytical function for the beta absorbed fraction, depending on a generalized radius for ellipsoid based on the radius of sphere, and a linear fit function for the gamma absorbed fraction. CONCLUSION: The analytical functions that we obtained from fitting process in Monte Carlo data can be used for obtaining the absorbed fractions of iodine-131 beta and gamma rays for any volume of the thyroid lobe. Moreover, our results for the spheres are in good agreement with the results of MIRD and other scientific literatures.


Subject(s)
Iodine Radioisotopes , Prostate/diagnostic imaging , Radiometry/methods , Thyroid Gland/diagnostic imaging , Beta Particles , Computer Simulation , Gamma Rays , Humans , Iodine Radioisotopes/chemistry , Male , Monte Carlo Method , Phantoms, Imaging , Radiation Dosage , Radionuclide Imaging , Radiopharmaceuticals , Tissue Distribution
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