ABSTRACT
Gardnerella vaginalis is an anaerobic gram variable organism, which commonly causes bacterial vaginosis in women. It is uncommon for this organism to cause a urinary tract infection in males. We present a case of G. vaginalis bacteremia in the setting of urolithiasis in an otherwise immunocompetent elderly male. He was treated with metronidazole alone for a 10-day course with resolution of symptoms and negative repeat blood cultures. It is important for health care professionals to acknowledge this rare cause of infection in males and adequately treat to prevent increased morbidity and mortality.
ABSTRACT
BACKGROUND Mucormycosis is a serious, potentially fatal fungal infection caused by species in the Mucorales order. Together with candidiasis and aspergillosis, it is one of the most significant fungal infection that carries a high rate of mortality. Early detection and initiation of antifungal therapy with adequate surgical debridement improves the clinical outcome. CASE REPORT We describe a case of mucormycosis in a patient with acute myeloid leukemia who developed disseminated lung disease with muscular involvement without any cutaneous manifestation. Successful treatment was achieved with surgical debridement, amphotericin B lipid-complex and posaconazole step-down therapy. CONCLUSIONS Mucormycosis can present in various clinical scenarios. Key to diagnosis depends on tissues diagnosis from the affected system, as was done with lung and muscle biopsy in our patient. Clinicians should maintain high suspicion for early diagnosis and prompt treatment.
Subject(s)
Leukemia, Myeloid, Acute/complications , Lung Diseases, Fungal/microbiology , Mucormycosis/diagnosis , Muscular Diseases/microbiology , Amphotericin B/therapeutic use , Antifungal Agents/therapeutic use , Female , Humans , Lung Diseases, Fungal/drug therapy , Middle Aged , Mucormycosis/drug therapy , Muscular Diseases/drug therapy , Opportunistic Infections/drug therapy , Opportunistic Infections/microbiologyABSTRACT
BACKGROUND Varicella zoster virus (VZV) is a common viral infection, with primary infection presenting as fevers and pruritic vesicular rash. After staying dormant in the dorsal root ganglia, reactivation can lead to secondary infection. Meningitis is a rare a complication of VZV infection. CASE REPORT We report a case of a 44-year-old woman with no past medical history, presenting with severe frontal headache without meningeal signs or fevers, found to have VZV meningitis. CSF analysis revealed hypoglycorrhachia and she was treated successfully with combination of intravenous acyclovir and oral valacyclovir. CONCLUSIONS VZV meningitis can present with subtle clinical signs and symptoms and should be considered as a possible etiology for headaches without identifiable cause.