ABSTRACT
The aim of this study was to evaluate and compare the efficacy of antiplaque mouthwashes. Plaque levels were determined by applying a plaque-disclosing solution using the Turesky et al modification of the Quigley Hein plaque index. The control group (n = 6) brushed twice per day with fluoride toothpaste for one minute and rinsed with water, while the study groups (n = 6) brushed once per day with fluoride toothpaste for one minute, followed by rinsing with 5.0 mL of mouthwash diluted with 10.0 mL of water for 30 seconds. The control group brushed and rinsed with water twice per day. The results indicated that cetylpyridinium chloride in combination with sodium fluoride offered maximum plaque inhibition, followed by chlorhexidine gluconate and sodium monofluorophosphate, while plaque levels increased in the control group and with the combination of chlorhexidine gluconate and sodium fluoride. The only antiplaque agents to demonstrate a statistically significant difference from the control were cetylpyridinium chloride in combination with sodium fluoride, and chlorhexidine gluconate. Increasing the fluoride concentration had no impact on antiplaque activity.
Subject(s)
Anti-Infective Agents, Local/therapeutic use , Cariostatic Agents/therapeutic use , Dental Plaque/prevention & control , Mouthwashes/therapeutic use , Adolescent , Adult , Anti-Infective Agents, Local/administration & dosage , Cariostatic Agents/administration & dosage , Cetylpyridinium/administration & dosage , Cetylpyridinium/therapeutic use , Chlorhexidine/administration & dosage , Chlorhexidine/analogs & derivatives , Chlorhexidine/therapeutic use , Coloring Agents , Dental Plaque/classification , Dental Plaque Index , Fluorides/administration & dosage , Fluorides/therapeutic use , Follow-Up Studies , Humans , Middle Aged , Phosphates/administration & dosage , Phosphates/therapeutic use , Sodium Fluoride/administration & dosage , Sodium Fluoride/therapeutic use , Toothpastes/therapeutic use , Treatment Outcome , Young AdultABSTRACT
OBJECTIVE: To establish the presence and quantify Ethanol in commercially available mouthwashes. METHODS: Samples from twelve commercially available mouthwashes were tested for the presence of Ethanol followed by the estimation of percentage of Ethanol in five brands in Pakistan Council of Scientific and Industrial Research (P.C.S.I.R) and Husein Ebrahim Jamal (H.E.J.) labs, Karachi. RESULTS: Ten out of twelve brands of mouthwashes were found to be Ethanol positive. CONCLUSION: Alcohol (Ethanol) in the mouthwashes does not contribute to any therapeutic action. It is alarming to find the presence of alcohol in the mouthwashes which claim to contain no alcohol.