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1.
PLoS One ; 18(10): e0290433, 2023.
Article in English | MEDLINE | ID: mdl-37851629

ABSTRACT

Kawaii, which is a Japanese word that means cute, lovely, and adorable, is an essential factor in promoting positive emotions in people. The characteristics of a target's appearance that induce such feelings of kawaii have been thoroughly investigated around the notion of Konrad Lorenz's famous baby schema. Such knowledge has been exploited to design the appearance of commercial products to increase their social acceptance and commercial appeal. However, the effects of the number of targets and showing their mutual relationships (like friendship) have not been investigated in the context of kawaii. Therefore, in this study, we conducted three web-based experiments and focused on how such factors contribute to feelings of kawaii toward social robots. In Experiment 1, the feelings of kawaii toward static images of targets were compared when they appeared alone or with another target: persons (twin boys/girls), non-human objects (cherries), and social robots. The results showed that the feeling of kawaii was stronger for two targets that displayed a mutual relationship (e.g., looking at each other and/or making physical contact) than for one target alone and for two-independent targets. In Experiment 2, these findings were replicated using video clips of robots. Two-related targets were rated as more kawaii than two-independent targets or a single target. These two experiments consistently show the advantage of multiple robots that display their mutual relationship for enhancing the viewer's feeling of kawaii. Experiment 3 examined the effect of the number of robots (from one to ten) and found that two robots induced the strongest feeling of kawaii. These results indicate that not only the physical characteristics of a target itself but also the number of targets and their perceived relationships affect feelings of kawaii.


Subject(s)
Robotics , Humans , Robotics/methods , Social Interaction , Emotions , Friends , Physical Examination
2.
Int J Mol Sci ; 25(1)2023 Dec 21.
Article in English | MEDLINE | ID: mdl-38203320

ABSTRACT

In this study, we applied argon plasma treatment to titanium surfaces with nanostructures deposited by concentrated alkali treatment and investigated the effects on the surface of the material and the tissue surrounding an implant site. The results showed that the treatment with argon plasma removed carbon contaminants and increased the surface energy of the material while the nanoscale network structure deposited on the titanium surface remained in place. Reactive oxygen species reduced the oxidative stress of bone marrow cells on the treated titanium surface, creating a favorable environment for cell proliferation. Good results were observed in vitro evaluations using rat bone marrow cells. The group treated with argon plasma exhibited the highest apatite formation in experiments using simulated body fluids. The results of in vivo evaluation using rat femurs revealed that the treatment improved the amount of new bone formation around an implant. Thus, the results demonstrate that argon plasma treatment enhances the ability of nanostructured titanium surfaces to induce hard tissue differentiation and supports new bone formation around an implant site.


Subject(s)
Nanostructures , Plasma Gases , Animals , Rats , Argon/pharmacology , Titanium/pharmacology , Plasma Gases/pharmacology , Plasma
3.
Int J Mol Sci ; 22(14)2021 Jul 16.
Article in English | MEDLINE | ID: mdl-34299241

ABSTRACT

In this paper, we suggest that the atmospheric pressure plasma treatment of pure titanium metal may be useful for improving the ability of rat bone marrow cells (RBMCs) to induce hard tissue differentiation. Previous studies have reported that the use of argon gas induces a higher degree of hard tissue formation. Therefore, this study compares the effects of plasma treatment with argon gas on the initial adhesion ability and hard tissue differentiation-inducing ability of RBMCs. A commercially available titanium metal plate was used as the experimental material. A plate polished using water-resistant abrasive paper #1500 was used as the control, and a plate irradiated with argon mixed with atmospheric pressure plasma was used as the experimental plate. No structural change was observed on the surface of the titanium metal plate in the scanning electron microscopy results, and no change in the surface roughness was observed via scanning probe microscopy. X-ray photoelectron spectroscopy showed a decrease in the carbon peak and the formation of hydroxide in the experimental group. In the distilled water drop test, a significant decrease in the contact angle was observed for the experimental group, and the results indicated superhydrophilicity. Furthermore, the bovine serum albumin adsorption, initial adhesion of RBMCs, alkaline phosphatase activity, calcium deposition, and genetic marker expression of rat bone marrow cells were higher in the experimental group than those in the control group at all time points. Rat distal femur model are used as in vivo model. Additionally, microcomputed tomography analysis showed significantly higher results for the experimental group, indicating a large amount of the formed hard tissue. Histopathological evaluation also confirmed the presence of a prominent newly formed bone seen in the images of the experimental group. These results indicate that the atmospheric pressure plasma treatment with argon gas imparts superhydrophilicity, without changing the properties of the pure titanium plate surface. It was also clarified that it affects the initial adhesion of bone marrow cells and the induction of hard tissue differentiation.


Subject(s)
Argon/pharmacology , Osseointegration/drug effects , Plasma Gases/chemistry , Animals , Argon/chemistry , Atmospheric Pressure , Bone Marrow Cells/drug effects , Cell Adhesion/drug effects , Male , Microscopy, Electron, Scanning/methods , Osseointegration/physiology , Osteogenesis/drug effects , Photoelectron Spectroscopy/methods , Plasma Gases/pharmacology , Rats , Rats, Sprague-Dawley , Surface Properties , Titanium/chemistry , X-Ray Microtomography/methods
4.
J Patient Saf ; 16(1): 98-105, 2020 03.
Article in English | MEDLINE | ID: mdl-29140886

ABSTRACT

OBJECTIVE: The aim of the present observational study was to identify safe and suitable venipuncture sites for nursing in the clinical setting using ultrasonography to measure the depth and cross-sectional area of each superficial vein before and after tourniquet application as well as the distance between each superficial vein and the median nerve or brachial artery. METHODS AND RESULTS: Twenty healthy volunteers (21.8 [0.6] y) were recruited. The visible rate of each superficial vein before and after tourniquet application was 65% for the basilic vein, 90% to 95% for the median cubital vein, and 65% to 80% for the cephalic vein. The cross-sectional area of the median cubital vein after tourniquet application was significantly larger than that of the basilic vein and cephalic vein. The distance between the basilic vein or median cubital vein and median nerve was significantly smaller than that between the cephalic vein and median nerve. The distance between the basilic vein or median cubital vein and brachial artery was significantly smaller than that between the cephalic vein and brachial artery. CONCLUSIONS: These results demonstrated that the cephalic vein at the cubital fossa is a relatively safe venipuncture site because of its distance from the median nerve and brachial artery. When puncturing the cephalic vein is difficult because it is not visible, the median cubital vein at the cubital fossa may be selected for venipuncture due to its cross-sectional area and visibility; however, care is needed to avoid penetrating the vein because the median nerve and brachial artery are located underneath.


Subject(s)
Forearm/blood supply , Phlebotomy/methods , Ultrasonography/methods , Adult , Female , Healthy Volunteers , Humans , Male , Young Adult
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